Class information for:
Level 1: BURNS TRAUMA CRIT CARE//MEROPENEM//AUGMENTED RENAL CLEARANCE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8152 1286 34.1 79%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
233 3       JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY//ANTIMICROBIAL AGENTS AND CHEMOTHERAPY//FLUOROQUINOLONES 48717
451 2             JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY//ANTIMICROBIAL AGENTS AND CHEMOTHERAPY//CHEMOTHERAPY-TOKYO 16125
8152 1                   BURNS TRAUMA CRIT CARE//MEROPENEM//AUGMENTED RENAL CLEARANCE 1286

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BURNS TRAUMA CRIT CARE address 1152656 11% 33% 146
2 MEROPENEM authKW 405586 7% 19% 90
3 AUGMENTED RENAL CLEARANCE authKW 343079 1% 85% 17
4 ANTIINFECT DEV address 315362 5% 23% 59
5 PIPERACILLIN authKW 313096 4% 25% 52
6 EXTENDED INFUSION authKW 290846 1% 88% 14
7 CLIN PHARMACOTHER Y address 260554 2% 37% 30
8 TAZOBACTAM authKW 257341 3% 31% 35
9 CONTINUOUS INFUSION authKW 238299 6% 14% 71
10 PROLONGED INFUSION authKW 220965 2% 42% 22

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 12952 58% 0% 746
2 Infectious Diseases 10787 28% 0% 354
3 Microbiology 8241 34% 0% 435
4 Critical Care Medicine 4520 12% 0% 152
5 Urology & Nephrology 372 6% 0% 73
6 Transplantation 130 2% 0% 32
7 Anesthesiology 121 2% 0% 28
8 Medical Laboratory Technology 88 2% 0% 21
9 Toxicology 18 2% 0% 25
10 Biochemical Research Methods 18 2% 0% 29

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BURNS TRAUMA CRIT CARE 1152656 11% 33% 146
2 ANTIINFECT DEV 315362 5% 23% 59
3 CLIN PHARMACOTHER Y 260554 2% 37% 30
4 ANTI INFECT DEV 119158 1% 31% 16
5 BASIL HETZEL TRANSLAT HLTH 87649 1% 31% 12
6 PHARMACOCINET TOXICOL CLIN 60775 1% 20% 13
7 HYPERBAR INTENS CARE MED 53420 0% 75% 3
8 EPE PRACETA PROF MOTA PINTO 47486 0% 100% 2
9 PRINCETON CORP 47486 0% 100% 2
10 INTENS CARE MED 45627 7% 2% 85

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 46961 7% 2% 87
2 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 25997 13% 1% 161
3 JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 17831 8% 1% 97
4 PHARMACOTHERAPY 10076 3% 1% 44
5 JOURNAL OF INFECTION AND CHEMOTHERAPY 9225 2% 2% 21
6 ANNALS OF PHARMACOTHERAPY 3931 2% 1% 30
7 INTENSIVE CARE MEDICINE 3682 2% 1% 31
8 CLINICAL PHARMACOKINETICS 3610 1% 1% 19
9 CLINICAL THERAPEUTICS 2956 2% 1% 25
10 CRITICAL CARE 2951 2% 1% 22

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MEROPENEM 405586 7% 19% 90 Search MEROPENEM Search MEROPENEM
2 AUGMENTED RENAL CLEARANCE 343079 1% 85% 17 Search AUGMENTED+RENAL+CLEARANCE Search AUGMENTED+RENAL+CLEARANCE
3 PIPERACILLIN 313096 4% 25% 52 Search PIPERACILLIN Search PIPERACILLIN
4 EXTENDED INFUSION 290846 1% 88% 14 Search EXTENDED+INFUSION Search EXTENDED+INFUSION
5 TAZOBACTAM 257341 3% 31% 35 Search TAZOBACTAM Search TAZOBACTAM
6 CONTINUOUS INFUSION 238299 6% 14% 71 Search CONTINUOUS+INFUSION Search CONTINUOUS+INFUSION
7 PROLONGED INFUSION 220965 2% 42% 22 Search PROLONGED+INFUSION Search PROLONGED+INFUSION
8 PHARMACODYNAMICS 204186 16% 4% 201 Search PHARMACODYNAMICS Search PHARMACODYNAMICS
9 PIPERACILLIN TAZOBACTAM 157740 3% 18% 36 Search PIPERACILLIN+TAZOBACTAM Search PIPERACILLIN+TAZOBACTAM
10 PROBABILITY OF TARGET ATTAINMENT 105758 1% 64% 7 Search PROBABILITY+OF+TARGET+ATTAINMENT Search PROBABILITY+OF+TARGET+ATTAINMENT

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 GRUPPER, M , KUTI, JL , NICOLAU, DP , (2016) CONTINUOUS AND PROLONGED INTRAVENOUS BETA-LACTAM DOSING: IMPLICATIONS FOR THE CLINICAL LABORATORY.CLINICAL MICROBIOLOGY REVIEWS. VOL. 29. ISSUE 4. P. 759 -772 91 81% 0
2 SIME, FB , ROBERTS, MS , PEAKE, SL , LIPMAN, J , ROBERTS, JA , (2012) DOES BETA-LACTAM PHARMACOKINETIC VARIABILITY IN CRITICALLY ILL PATIENTS JUSTIFY THERAPEUTIC DRUG MONITORING? A SYSTEMATIC REVIEW.ANNALS OF INTENSIVE CARE. VOL. 2. ISSUE . P. - 83 77% 33
3 SINNOLLAREDDY, MG , ROBERTS, MS , LIPMAN, J , ROBERTS, JA , (2012) BETA-LACTAM PHARMACOKINETICS AND PHARMACODYNAMICS IN CRITICALLY ILL PATIENTS AND STRATEGIES FOR DOSE OPTIMIZATION: A STRUCTURED REVIEW.CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY. VOL. 39. ISSUE 6. P. 489 -496 71 77% 13
4 UDY, AA , ROBERTS, JA , LIPMAN, J , (2013) CLINICAL IMPLICATIONS OF ANTIBIOTIC PHARMACOKINETIC PRINCIPLES IN THE CRITICALLY ILL.INTENSIVE CARE MEDICINE. VOL. 39. ISSUE 12. P. 2070-2082 71 61% 40
5 OSTHOFF, M , SIEGEMUND, M , BALESTRA, G , ABDUL-AZIZ, MH , ROBERTS, JA , (2016) PROLONGED ADMINISTRATION OF BETA-LACTAM ANTIBIOTICS - A COMPREHENSIVE REVIEW AND CRITICAL APPRAISAL.SWISS MEDICAL WEEKLY. VOL. 146. ISSUE . P. - 60 80% 0
6 CHOI, G , GOMERSALL, CD , TIAN, Q , JOYNT, GM , FREEBAIRN, R , LIPMAN, J , (2009) PRINCIPLES OF ANTIBACTERIAL DOSING IN CONTINUOUS RENAL REPLACEMENT THERAPY.CRITICAL CARE MEDICINE. VOL. 37. ISSUE 7. P. 2268 -2282 69 66% 62
7 ROBERTS, JA , ABDUL-AZIZ, MH , LIPMAN, J , MOUTON, JW , VINKS, AA , FELTON, TW , HOPE, WW , FARKAS, A , NEELY, MN , SCHENTAG, JJ , ET AL (2014) INDIVIDUALISED ANTIBIOTIC DOSING FOR PATIENTS WHO ARE CRITICALLY ILL: CHALLENGES AND POTENTIAL SOLUTIONS.LANCET INFECTIOUS DISEASES. VOL. 14. ISSUE 6. P. 498-509 65 47% 63
8 ABDUL-AZIZ, MH , DULHUNTY, JM , BELLOMO, R , LIPMAN, J , ROBERTS, JA , (2012) CONTINUOUS BETA-LACTAM INFUSION IN CRITICALLY ILL PATIENTS: THE CLINICAL EVIDENCE.ANNALS OF INTENSIVE CARE. VOL. 2. ISSUE . P. - 64 68% 20
9 ABDUL-AZIZ, MH , LIPMAN, J , AKOVA, M , BASSETTI, M , DE WAELE, JJ , DIMOPOULOS, G , DULHUNTY, J , KAUKONEN, KM , KOULENTI, D , MARTIN, C , ET AL (2016) IS PROLONGED INFUSION OF PIPERACILLIN/TAZOBACTAM AND MEROPENEM IN CRITICALLY ILL PATIENTS ASSOCIATED WITH IMPROVED PHARMACOKINETIC/PHARMACODYNAMIC AND PATIENT OUTCOMES? AN OBSERVATION FROM THE DEFINING ANTIBIOTIC LEVELS IN INTENSIVE CARE UNIT PATIENTS (DALI) COHORT.JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. VOL. 71. ISSUE 1. P. 196 -207 40 87% 3
10 GONCALVES-PEREIRA, J , POVOA, P , (2011) ANTIBIOTICS IN CRITICALLY ILL PATIENTS: A SYSTEMATIC REVIEW OF THE PHARMACOKINETICS OF BETA-LACTAMS.CRITICAL CARE. VOL. 15. ISSUE 5. P. - 56 65% 87

Classes with closest relation at Level 1


Rank Class id link
1 7351 DORIPENEM//ERTAPENEM//MEROPENEM
2 5153 AMINOGLYCOSIDES//GENTAMICIN//AMIKACIN
3 5145 VANCOMYCIN//TEICOPLANIN//RED MAN SYNDROME
4 15846 CEFEPIME//CEFPIROME//CEFPIROME SULFATE
5 22341 AVIBACTAM//CEFTOLOZANE TAZOBACTAM//CEFTAZIDIME AVIBACTAM
6 16319 POSTANTIBIOTIC EFFECT//POSTANTIBIOTIC SUB MIC EFFECT//POST ANTIBIOTIC EFFECT PAE
7 3327 GEMIFLOXACIN//CEFDITOREN//GEMIFLOXACIN MESYLATE
8 19495 MEZLOCILLIN//ANTIBACTERIALS ALTERNATIVE SCREENING METHOD//BILIARY PHARMACOKINETICS
9 11826 SULBACTAM//SULTAMICILLIN//AMPICILLIN SULBACTAM
10 3292 CONTINUOUS RENAL REPLACEMENT THERAPY//HEMOFILTRATION//REGIONAL CITRATE ANTICOAGULATION

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