Class information for:
Level 1: CARBAMAZEPINE 10 11 EPOXIDE//CARBAMAZEPINE//THERAPEUTIC DRUG MONITORING

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6145 1522 28.2 49%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
143 3       EPILEPSY//EPILEPSIA//EPILEPSY & BEHAVIOR 64226
230 2             ANTIEPILEPTIC DRUGS//LEVETIRACETAM//EPILEPSY 20331
6145 1                   CARBAMAZEPINE 10 11 EPOXIDE//CARBAMAZEPINE//THERAPEUTIC DRUG MONITORING 1522

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARBAMAZEPINE 10 11 EPOXIDE authKW 391423 2% 51% 38
2 CARBAMAZEPINE authKW 374130 14% 9% 215
3 THERAPEUTIC DRUG MONITORING journal 255530 14% 6% 218
4 PHENYTOIN authKW 202359 8% 8% 120
5 FREE PHENYTOIN authKW 180543 1% 75% 12
6 CARBAMAZEPINE EPOXIDE authKW 65525 0% 47% 7
7 CARBAMAZEPINE 10 11 DIOL authKW 60183 0% 100% 3
8 FREE DIGITOXIN authKW 60183 0% 100% 3
9 FREE VALPROIC ACID authKW 60183 0% 100% 3
10 SHEINER TOZER EQUATION authKW 60183 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Medical Laboratory Technology 19197 19% 0% 285
2 Pharmacology & Pharmacy 14148 56% 0% 850
3 Toxicology 4430 17% 0% 253
4 Clinical Neurology 2045 17% 0% 260
5 Chemistry, Analytical 560 10% 0% 146
6 Medicine, General & Internal 133 6% 0% 92
7 Biochemical Research Methods 81 3% 0% 52
8 Psychiatry 71 4% 0% 55
9 Pediatrics 53 3% 0% 47
10 Chemistry, Medicinal 35 2% 0% 34

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HORMONOL THER EUT DRUG MONITORING 26747 0% 67% 2
2 ACUTE CARE STREAM 20061 0% 100% 1
3 ASSURANCE QUAL S ANAL BIOL MED 20061 0% 100% 1
4 BIOCHIM PHARMACOL TOXICOL TRACES 20061 0% 100% 1
5 CATEDRA TOXICOL BIOQUIM 20061 0% 100% 1
6 CENT MED BIOCHEM 20061 0% 100% 1
7 CHEM EVORA CQE 20061 0% 100% 1
8 CHEM TECHNOL ANALYTI CHEM 20061 0% 100% 1
9 CLIN CLIN PHARMACOLTOYAMA CHO 1 20061 0% 100% 1
10 CLIN PHARMACOKINET CONSULTAT SERV 20061 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 THERAPEUTIC DRUG MONITORING 255530 14% 6% 218
2 CLINICAL PHARMACOKINETICS 21244 3% 2% 50
3 EPILEPSIA 13272 5% 1% 77
4 JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS 9532 2% 1% 32
5 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 7413 4% 1% 55
6 CLINICAL PHARMACY 5863 1% 2% 15
7 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 3040 2% 0% 33
8 INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS 2928 2% 1% 24
9 CLINICAL PHARMACOLOGY & THERAPEUTICS 2468 2% 0% 27
10 BIOPHARMACEUTICS & DRUG DISPOSITION 2318 1% 1% 15

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CARBAMAZEPINE 10 11 EPOXIDE 391423 2% 51% 38 Search CARBAMAZEPINE+10+11+EPOXIDE Search CARBAMAZEPINE+10+11+EPOXIDE
2 CARBAMAZEPINE 374130 14% 9% 215 Search CARBAMAZEPINE Search CARBAMAZEPINE
3 PHENYTOIN 202359 8% 8% 120 Search PHENYTOIN Search PHENYTOIN
4 FREE PHENYTOIN 180543 1% 75% 12 Search FREE+PHENYTOIN Search FREE+PHENYTOIN
5 CARBAMAZEPINE EPOXIDE 65525 0% 47% 7 Search CARBAMAZEPINE+EPOXIDE Search CARBAMAZEPINE+EPOXIDE
6 CARBAMAZEPINE 10 11 DIOL 60183 0% 100% 3 Search CARBAMAZEPINE+10+11+DIOL Search CARBAMAZEPINE+10+11+DIOL
7 FREE DIGITOXIN 60183 0% 100% 3 Search FREE+DIGITOXIN Search FREE+DIGITOXIN
8 FREE VALPROIC ACID 60183 0% 100% 3 Search FREE+VALPROIC+ACID Search FREE+VALPROIC+ACID
9 SHEINER TOZER EQUATION 60183 0% 100% 3 Search SHEINER+TOZER+EQUATION Search SHEINER+TOZER+EQUATION
10 CARBAMAZEPINE DIOL 45136 0% 75% 3 Search CARBAMAZEPINE+DIOL Search CARBAMAZEPINE+DIOL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KONG, ST , LIM, SH , CHAN, E , HO, PC , (2014) ESTIMATION AND COMPARISON OF CARBAMAZEPINE POPULATION PHARMACOKINETICS USING DRIED BLOOD SPOT AND PLASMA CONCENTRATIONS FROM PEOPLE WITH EPILEPSY: THE CLINICAL IMPLICATION.JOURNAL OF CLINICAL PHARMACOLOGY. VOL. 54. ISSUE 2. P. 225-233 30 79% 7
2 BATTINO, D , ESTIENNE, M , AVANZINI, G , (1995) CLINICAL PHARMACOKINETICS OF ANTIEPILEPTIC DRUGS IN PEDIATRIC-PATIENTS .2. PHENYTOIN, CARBAMAZEPINE, SULTHIAME, LAMOTRIGINE, VIGABATRIN, OXCARBAZEPINE AND FELBAMATE.CLINICAL PHARMACOKINETICS. VOL. 29. ISSUE 5. P. 341-369 58 67% 55
3 RIVA, R , ALBANI, F , CONTIN, M , BARUZZI, A , (1996) PHARMACOKINETIC INTERACTIONS BETWEEN ANTIEPILEPTIC DRUGS - CLINICAL CONSIDERATIONS.CLINICAL PHARMACOKINETICS. VOL. 31. ISSUE 6. P. 470-493 68 48% 112
4 LEVINE, M , CHANG, T , (1990) THERAPEUTIC DRUG-MONITORING OF PHENYTOIN - RATIONALE AND CURRENT STATUS.CLINICAL PHARMACOKINETICS. VOL. 19. ISSUE 5. P. 341-358 59 78% 41
5 YUKAWA, E , (1996) OPTIMISATION OF ANTIEPILEPTIC DRUG THERAPY - THE IMPORTANCE OF SERUM DRUG CONCENTRATION MONITORING.CLINICAL PHARMACOKINETICS. VOL. 31. ISSUE 2. P. 120-130 47 75% 29
6 KIANG, TKL , ENSOM, MHH , (2016) A COMPREHENSIVE REVIEW ON THE PREDICTIVE PERFORMANCE OF THE SHEINER-TOZER AND DERIVATIVE EQUATIONS FOR THE CORRECTION OF PHENYTOIN CONCENTRATIONS.ANNALS OF PHARMACOTHERAPY. VOL. 50. ISSUE 4. P. 311 -325 21 88% 0
7 PATSALOS, PN , BERRY, DJ , BOURGEOIS, BFD , CLOYD, JC , GLAUSER, TA , JOHANNESSEN, SI , LEPPIK, IE , TOMSON, T , PERUCCA, E , (2008) ANTIEPILEPTIC DRUGS - BEST PRACTICE GUIDELINES FOR THERAPEUTIC DRUG MONITORING: A POSITION PAPER BY THE SUBCOMMISSION ON THERAPEUTIC DRUG MONITORING, ILAE COMMISSION ON THERAPEUTIC STRATEGIES.EPILEPSIA. VOL. 49. ISSUE 7. P. 1239 -1276 71 21% 249
8 POWELL, G , SAUNDERS, M , RIGBY, A , MARSON, AG , (2014) IMMEDIATE-RELEASE VERSUS CONTROLLED-RELEASE CARBAMAZEPINE IN THE TREATMENT OF EPILEPSY.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 12. P. - 19 95% 0
9 BERTILSSON, L , TOMSON, T , (1986) CLINICAL PHARMACOKINETICS AND PHARMACOLOGICAL EFFECTS OF CARBAMAZEPINE AND CARBAMAZEPINE-10,11-EPOXIDE - AN UPDATE.CLINICAL PHARMACOKINETICS. VOL. 11. ISSUE 3. P. 177-198 50 72% 212
10 JIAO, Z , SHI, XJ , ZHAO, ZG , ZHONG, MK , (2004) POPULATION PHARMACOKINETIC MODELING OF STEADY STATE CLEARANCE OF CARBAMAZEPINE AND ITS EPOXIDE METABOLITE FROM SPARSE ROUTINE CLINICAL DATA.JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS. VOL. 29. ISSUE 3. P. 247-256 25 89% 16

Classes with closest relation at Level 1


Rank Class id link
1 27814 FOSPHENYTOIN//PURPLE GLOVE SYNDROME//PHENYTOIN
2 22924 BROMATOL NUTR DIETET//INSTRUMENTAL PLANAR CHROMATOGRAPHY//10 11 DIHYDRO 10 HYDROXYCARBAMAZEPINE MHD
3 3055 LAMOTRIGINE//FELBAMATE//OXCARBAZEPINE
4 27035 CHEMICAL REACTION INTERFACE MASS SPECTROMETRY//PHARMACOL RE6640//SPP301
5 3625 VALPROIC ACID//VALPROATE//VALNOCTAMIDE
6 20462 VERDUN HOSP//CHARCOAL HEMOPERFUSION//HEMOPERFUSION
7 22976 DIGOXIN ASSAY//VISUAL MEMBRANE IMMUNOASSAY//ALKALINE PHOSPHATASE LABEL
8 24335 ANTIBODIES IMMOBILISED ON A SOLID PHASE//ASSAY THEOPHYLLINE//CENT BIOCHEM BIOPHYS
9 19737 SEMI MICROCOLUMN LIQUID CHROMATOGRAPHY//RESTRICTED ACCESS MEDIA//MIXED FUNCTIONAL PHASE
10 23464 TABLET SPLITTING//SCORED TABLETS//SCORE LINE

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