Class information for:
Level 1: ALKYLPHOSPHOCHOLINES//HEXADECYLPHOSPHOCHOLINE//EDELFOSINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6043 1539 34.0 63%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
429 3       SPHINGOSINE 1 PHOSPHATE//CERAMIDE//SPHINGOLIPIDS 27734
1114 2             PHOSPHOLIPASE A2//PLASMALOGEN//LIPIDOMICS 9711
6043 1                   ALKYLPHOSPHOCHOLINES//HEXADECYLPHOSPHOCHOLINE//EDELFOSINE 1539

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ALKYLPHOSPHOCHOLINES authKW 972100 4% 78% 63
2 HEXADECYLPHOSPHOCHOLINE authKW 905050 4% 72% 63
3 EDELFOSINE authKW 830448 4% 70% 60
4 ALKYL LYSOPHOSPHOLIPIDS authKW 676622 2% 95% 36
5 PERIFOSINE authKW 609566 3% 59% 52
6 ALKYLPHOSPHOLIPIDS authKW 533341 2% 79% 34
7 ET 18 OCH3 authKW 463458 2% 81% 29
8 ERUFOSINE authKW 301763 1% 89% 17
9 ERUCYLPHOSPHOCHOLINE authKW 243028 1% 88% 14
10 ETHER LIPIDS authKW 230591 3% 25% 46

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 3899 27% 0% 418
2 Chemistry, Organic 1972 17% 0% 267
3 Biochemistry & Molecular Biology 1641 30% 0% 458
4 Biophysics 1372 12% 0% 180
5 Chemistry, Medicinal 889 8% 0% 120
6 Pharmacology & Pharmacy 594 14% 0% 212
7 Nutrition & Dietetics 367 5% 0% 72
8 Chemistry, Multidisciplinary 111 9% 0% 133
9 Hematology 81 3% 0% 47
10 Cell Biology 56 5% 0% 81

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHEM POLYMERS TECHNOL 99197 0% 100% 5
2 BIOL MOL CELULAR CANC 98146 3% 11% 45
3 INVEST CANC 62372 3% 7% 44
4 TOXICOL CHEMOTHER Y UNIT 48374 1% 24% 10
5 UNIT TOXICOL CHEMOTHER Y 41316 1% 21% 10
6 SCI ST JEROME D12 26451 0% 67% 2
7 AG TOXICOL CHEMOTHER IE 0426 19839 0% 100% 1
8 BIOL CYTOL HISTOL EMBRYOL 19839 0% 100% 1
9 BIOPHYS INSERM U201 19839 0% 100% 1
10 BOSTON VET ADM VA HEALTHCARE SYST 19839 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHEMISTRY AND PHYSICS OF LIPIDS 57748 6% 3% 97
2 PROGRESS IN EXPERIMENTAL TUMOR RESEARCH 21128 1% 7% 15
3 LIPIDS 14164 4% 1% 65
4 BIOORGANICHESKAYA KHIMIYA 13388 3% 1% 47
5 JOURNAL OF LIPID MEDIATORS AND CELL SIGNALLING 3496 0% 3% 7
6 ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY 2661 1% 1% 12
7 CANCER CHEMOTHERAPY AND PHARMACOLOGY 2550 2% 0% 31
8 DRUGS OF TODAY 1767 1% 1% 12
9 ONKOLOGIE 1477 1% 1% 14
10 RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY 1370 1% 1% 10

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ALKYLPHOSPHOCHOLINES 972100 4% 78% 63 Search ALKYLPHOSPHOCHOLINES Search ALKYLPHOSPHOCHOLINES
2 HEXADECYLPHOSPHOCHOLINE 905050 4% 72% 63 Search HEXADECYLPHOSPHOCHOLINE Search HEXADECYLPHOSPHOCHOLINE
3 EDELFOSINE 830448 4% 70% 60 Search EDELFOSINE Search EDELFOSINE
4 ALKYL LYSOPHOSPHOLIPIDS 676622 2% 95% 36 Search ALKYL+LYSOPHOSPHOLIPIDS Search ALKYL+LYSOPHOSPHOLIPIDS
5 PERIFOSINE 609566 3% 59% 52 Search PERIFOSINE Search PERIFOSINE
6 ALKYLPHOSPHOLIPIDS 533341 2% 79% 34 Search ALKYLPHOSPHOLIPIDS Search ALKYLPHOSPHOLIPIDS
7 ET 18 OCH3 463458 2% 81% 29 Search ET+18+OCH3 Search ET+18+OCH3
8 ERUFOSINE 301763 1% 89% 17 Search ERUFOSINE Search ERUFOSINE
9 ERUCYLPHOSPHOCHOLINE 243028 1% 88% 14 Search ERUCYLPHOSPHOCHOLINE Search ERUCYLPHOSPHOCHOLINE
10 ETHER LIPIDS 230591 3% 25% 46 Search ETHER+LIPIDS Search ETHER+LIPIDS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BRACHWITZ, H , VOLLGRAF, C , (1995) ANALOGS OF ALKYLLYSOPHOSPHOLIPIDS - CHEMISTRY, EFFECTS ON THE MOLECULAR-LEVEL AND THEIR CONSEQUENCES FOR NORMAL AND MALIGNANT-CELLS.PHARMACOLOGY & THERAPEUTICS. VOL. 66. ISSUE 1. P. 39-82 227 87% 85
2 HOULIHAN, WJ , LOHMEYER, M , WORKMAN, P , CHEON, SH , (1995) PHOSPHOLIPID ANTITUMOR AGENTS.MEDICINAL RESEARCH REVIEWS. VOL. 15. ISSUE 3. P. 157-223 202 79% 108
3 VAN BLITTERSWIJK, WJ , VERHEIJ, M , (2013) ANTICANCER MECHANISMS AND CLINICAL APPLICATION OF ALKYLPHOSPHOLIPIDS.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1831. ISSUE 3. P. 663-674 118 65% 52
4 JAFFRES, PA , GAJATE, C , BOUCHET, AM , COUTHON-GOURVES, H , CHANTOME, A , POTIER-CARTEREAU, M , BESSON, P , BOUGNOUX, P , MOLLINEDO, F , VANDIER, C , (2016) ALKYL ETHER LIPIDS, ION CHANNELS AND LIPID RAFT REORGANIZATION IN CANCER THERAPY.PHARMACOLOGY & THERAPEUTICS. VOL. 165. ISSUE . P. 114 -131 123 67% 1
5 KOSTADINOVA, A , TOPOUZOVA-HRISTOVA, T , MOMCHILOVA, A , TZONEVA, R , BERGER, MR , (2015) ANTITUMOR LIPIDS-STRUCTURE, FUNCTIONS, AND MEDICAL APPLICATIONS.ADVANCES IN PROTEIN CHEMISTRY AND STRUCTURAL BIOLOGY, VOL 101. VOL. 101. ISSUE . P. 27 -66 113 75% 0
6 GAJATE, C , MOLLINEDO, F , (2002) BIOLOGICAL ACTIVITIES, MECHANISMS OF ACTION AND BIOMEDICAL PROSPECT OF THE ANTITUMOR ETHER PHOSPHOLIPID ET-18-OCH3 (EDELFOSINE), A PROAPOPTOTIC AGENT IN TUMOR CELLS.CURRENT DRUG METABOLISM. VOL. 3. ISSUE 5. P. 491-525 188 53% 112
7 VERHEIJ, M , MOOLENAAR, WH , VAN BLITTERSWIJK, WJ , (2014) COMBINING ANTI-TUMOR ALKYL-PHOSPHOLIPID ANALOGS AND RADIOTHERAPY: RATIONALE AND CLINICAL OUTLOOK.ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. VOL. 14. ISSUE 4. P. 618 -628 81 77% 3
8 MOLLINEDO, F , (2007) ANTITUMOUR ETHER LIQUIDS: PROAPOPTOTIC AGENTS WITH MULTIPLE THERAPEUTIC INDICATIONS.EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 17. ISSUE 4. P. 385-405 101 72% 21
9 PRINCIPE, P , BRAQUET, P , (1995) ADVANCES IN ETHER PHOSPHOLIPIDS TREATMENT OF CANCER.CRITICAL REVIEWS IN ONCOLOGY/HEMATOLOGY. VOL. 18. ISSUE 3. P. 155-178 112 89% 24
10 VAN BLITTERSWIJK, WJ , VERHEIJ, M , (2008) ANTICANCER ALKYLPHOSPHOLIPIDS: MECHANISMS OF ACTION, CELLULAR SENSITIVITY AND RESISTANCE, AND CLINICAL PROSPECTS.CURRENT PHARMACEUTICAL DESIGN. VOL. 14. ISSUE 21. P. 2061-2074 94 57% 92

Classes with closest relation at Level 1


Rank Class id link
1 18029 TRANSPHOSPHATIDYLATION//ENZYMATIC DEGUMMING//STRUCTURED PHOSPHOLIPIDS
2 32337 FLUORESCENT LIPID PROBES//3 PERYLENOYL//3 PERYLENYL DERIVATIVES
3 35358 SPHINGOPHOSPHONOLIPIDS//2 ACYLOXYETHANEPHOSPHONATE//2 HYDROXYETHANEPHOSPHONATE
4 18442 ZHURNAL OBSHCHEI KHIMII//1 3 2 OXAZAPHOSPHINANES//TRIALKYLTRITHIOPHOSPHITE
5 36585 LIVISTONA CHINENSIS//RUELLIA PRAETERMISSA//DROSOPHILA FRUIT FLIES
6 37538 HETEROCYCLIC TRIOXIRANES//TEROXIRONE//HUMAN NON SMALL CELL LUNG CANCER CELLS
7 3390 LEISHMANIA//MILTEFOSINE//ANTIMONY RESISTANCE
8 278 PLATELET ACTIVATING FACTOR//PAF//PAF ANTAGONIST
9 19665 PLASMALOGEN//ALPHA HYDROXYALDEHYDES//PHOSPHATIDYLETHANOLAMINE PLASMALOGEN
10 12489 PRONUCLEOTIDES//PHOSPHORAMIDATE//PROTIDE

Go to start page