Class information for:
Level 1: ACUTE MYELOID LEUKEMIA//FLT3//FLT3 ITD

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
552 3317 42.4 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
51 3       HEMATOLOGY//BONE MARROW TRANSPLANTATION//BLOOD 91443
56 2             MYELODYSPLASTIC SYNDROME//HEMATOLOGY//ACUTE MYELOID LEUKEMIA 29625
552 1                   ACUTE MYELOID LEUKEMIA//FLT3//FLT3 ITD 3317

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ACUTE MYELOID LEUKEMIA authKW 1726468 27% 21% 899
2 FLT3 authKW 1562480 8% 66% 256
3 FLT3 ITD authKW 846282 4% 77% 119
4 AML authKW 631985 12% 17% 393
5 NPM1 authKW 403395 2% 62% 71
6 ACUTE MYELOID LEUKAEMIA authKW 330839 5% 22% 166
7 FLT3 MUTATIONS authKW 269193 1% 75% 39
8 NPM1 MUTATION authKW 263754 1% 87% 33
9 LEUKEMIA DIAGNOST address 249646 1% 59% 46
10 INTERNAL TANDEM DUPLICATION authKW 227652 1% 85% 29

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Hematology 130017 60% 1% 1987
2 Oncology 22898 43% 0% 1435
3 Transplantation 833 4% 0% 122
4 Medical Laboratory Technology 314 2% 0% 62
5 Pathology 257 3% 0% 106
6 Genetics & Heredity 106 4% 0% 128
7 Medicine, Research & Experimental 67 3% 0% 97
8 Immunology 66 4% 0% 137
9 Medicine, General & Internal 62 4% 0% 127
10 Cell Biology 58 4% 0% 145

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LEUKEMIA DIAGNOST 249646 1% 59% 46
2 HEMATOL 112860 23% 2% 777
3 MICROBIOL VIROL IMMUNOL MED GENET 82829 0% 75% 12
4 LEUKEMIA 78011 4% 6% 144
5 CLIN COOPERAT GRP LEUKEMIA 69723 1% 32% 24
6 ALLIANCE CLIN TRIALS ONCOL STAT DATA 62122 0% 75% 9
7 STEM CELL TRANSPLANTAT UNIT 51214 1% 19% 29
8 CLIN COOPERAT GRP ACUTE LEUKEMIAS 46019 0% 100% 5
9 LEUKEMIA SERV 42806 1% 12% 38
10 HEMATOL ONCOL 42768 13% 1% 440

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LEUKEMIA 55196 6% 3% 213
2 BLOOD 46253 13% 1% 416
3 BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY 42104 2% 7% 62
4 LEUKEMIA RESEARCH 34131 5% 2% 150
5 CURRENT OPINION IN HEMATOLOGY 18461 1% 4% 48
6 HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 15840 2% 3% 55
7 BLOOD CANCER JOURNAL 15060 1% 7% 22
8 CLINICAL LYMPHOMA MYELOMA & LEUKEMIA 14749 1% 5% 35
9 LEUKEMIA & LYMPHOMA 14527 3% 1% 110
10 CURRENT HEMATOLOGIC MALIGNANCY REPORTS 14191 1% 7% 22

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ACUTE MYELOID LEUKEMIA 1726468 27% 21% 899 Search ACUTE+MYELOID+LEUKEMIA Search ACUTE+MYELOID+LEUKEMIA
2 FLT3 1562480 8% 66% 256 Search FLT3 Search FLT3
3 FLT3 ITD 846282 4% 77% 119 Search FLT3+ITD Search FLT3+ITD
4 AML 631985 12% 17% 393 Search AML Search AML
5 NPM1 403395 2% 62% 71 Search NPM1 Search NPM1
6 ACUTE MYELOID LEUKAEMIA 330839 5% 22% 166 Search ACUTE+MYELOID+LEUKAEMIA Search ACUTE+MYELOID+LEUKAEMIA
7 FLT3 MUTATIONS 269193 1% 75% 39 Search FLT3+MUTATIONS Search FLT3+MUTATIONS
8 NPM1 MUTATION 263754 1% 87% 33 Search NPM1+MUTATION Search NPM1+MUTATION
9 INTERNAL TANDEM DUPLICATION 227652 1% 85% 29 Search INTERNAL+TANDEM+DUPLICATION Search INTERNAL+TANDEM+DUPLICATION
10 NORMAL KARYOTYPE 181768 1% 51% 39 Search NORMAL+KARYOTYPE Search NORMAL+KARYOTYPE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 DOHNER, H , ESTEY, EH , AMADORI, S , APPELBAUM, FR , BUCHNER, T , BURNETT, AK , DOMBRET, H , FENAUX, P , GRIMWADE, D , LARSON, RA , ET AL (2010) DIAGNOSIS AND MANAGEMENT OF ACUTE MYELOID LEUKEMIA IN ADULTS: RECOMMENDATIONS FROM AN INTERNATIONAL EXPERT PANEL, ON BEHALF OF THE EUROPEAN LEUKEMIANET.BLOOD. VOL. 115. ISSUE 3. P. 453 -474 148 50% 1005
2 LIERSCH, R , MULLER-TIDOW, C , BERDEL, WE , KRUG, U , (2014) PROGNOSTIC FACTORS FOR ACUTE MYELOID LEUKAEMIA IN ADULTS - BIOLOGICAL SIGNIFICANCE AND CLINICAL USE.BRITISH JOURNAL OF HAEMATOLOGY. VOL. 165. ISSUE 1. P. 17 -38 152 73% 17
3 DOMBRET, H , GARDIN, C , (2016) AN UPDATE OF CURRENT TREATMENTS FOR ADULT ACUTE MYELOID LEUKEMIA.BLOOD. VOL. 127. ISSUE 1. P. 53 -61 66 84% 14
4 KINDLER, T , LIPKA, DB , FISCHER, T , (2010) FLT3 AS A THERAPEUTIC TARGET IN AML: STILL CHALLENGING AFTER ALL THESE YEARS.BLOOD. VOL. 116. ISSUE 24. P. 5089-5102 99 80% 155
5 FERRARA, F , SCHIFFER, CA , (2013) ACUTE MYELOID LEUKAEMIA IN ADULTS.LANCET. VOL. 381. ISSUE 9865. P. 484-495 92 72% 110
6 LEUNG, AYH , MAN, CH , KWONG, YL , (2013) FLT3 INHIBITION: A MOVING AND EVOLVING TARGET IN ACUTE MYELOID LEUKAEMIA.LEUKEMIA. VOL. 27. ISSUE 2. P. 260-268 89 82% 37
7 BUCCISANO, F , MAURILLO, L , DEL PRINCIPE, MI , DEL POETA, G , SCONOCCHIA, G , LO-COCO, F , ARCESE, W , AMADORI, S , VENDITTI, A , (2012) PROGNOSTIC AND THERAPEUTIC IMPLICATIONS OF MINIMAL RESIDUAL DISEASE DETECTION IN ACUTE MYELOID LEUKEMIA.BLOOD. VOL. 119. ISSUE 2. P. 332-341 76 84% 99
8 TAMAMYAN, G , KADIA, T , RAVANDI, F , BORTHAKUR, G , CORTES, J , JABBOUR, E , DAVER, N , OHANIAN, M , KANTARJIAN, H , KONOPLEVA, M , (2017) FRONTLINE TREATMENT OF ACUTE MYELOID LEUKEMIA IN ADULTS.CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. VOL. 110. ISSUE . P. 20 -34 122 65% 0
9 KADIA, TM , RAVANDI, F , O'BRIEN, S , CORTES, J , KANTARJIAN, HM , (2015) PROGRESS IN ACUTE MYELOID LEUKEMIA.CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. VOL. 15. ISSUE 3. P. 139 -151 89 77% 10
10 BHUDIA, N , IVEY, A , HILLS, RK , SIMPSON, MA , JOVANOVIC, JV , GILKES, A , GRECH, A , PATEL, Y , FARAH, H , MASON, J , ET AL (2016) ASSESSMENT OF MINIMAL RESIDUAL DISEASE IN STANDARD-RISK AML.NEW ENGLAND JOURNAL OF MEDICINE. VOL. 374. ISSUE 5. P. 422 -433 31 89% 39

Classes with closest relation at Level 1


Rank Class id link
1 25496 AML IN CHILDREN//BFM AML GRP//HONG KONG PAEDIAT HAEMATOL ONCOL STUDY GRP
2 25493 LEUKEMIA STEM CELLS//LEUKEMIC STEM CELLS//CD123
3 3806 CYTOSINE ARABINOSIDE//ARA CTP//CYTARABINE
4 37469 AML CELL DEATH//ARSENIC TRIOXIDE 1//ATPASE BINDING CASSETTE ABC TRANSPORTERS
5 1137 MYELODYSPLASTIC SYNDROME//AZACITIDINE//MDS
6 4828 RUNX3//AML1 ETO//RUNX1
7 16782 MIR 196B//MICRORNA//KEY STATE MED MOL BIOL
8 11281 ANTIBODY DRUG CONJUGATE//GEMTUZUMAB OZOGAMICIN//MYLOTARG
9 28007 ACUTE ERYTHROLEUKEMIA//PURE ERYTHROID LEUKEMIA//ACUTE ERYTHROID LEUKEMIA
10 5973 MLL//MLL GENE//11Q23

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