Class information for:
Level 1: RUNX3//AML1 ETO//RUNX1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4828 1718 43.2 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
51 3       HEMATOLOGY//BONE MARROW TRANSPLANTATION//BLOOD 91443
56 2             MYELODYSPLASTIC SYNDROME//HEMATOLOGY//ACUTE MYELOID LEUKEMIA 29625
4828 1                   RUNX3//AML1 ETO//RUNX1 1718

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RUNX3 authKW 1346360 8% 57% 134
2 AML1 ETO authKW 916481 4% 68% 76
3 RUNX1 authKW 894285 7% 43% 117
4 AML1 authKW 696603 4% 56% 70
5 RUNX authKW 539586 3% 53% 57
6 T821 authKW 360300 2% 48% 42
7 T8 21 authKW 313492 1% 84% 21
8 INV16 authKW 244991 2% 48% 29
9 CBF BETA MYH11 authKW 223301 1% 74% 17
10 CBF BETA authKW 206944 1% 61% 19

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Hematology 18314 32% 0% 544
2 Oncology 8426 37% 0% 633
3 Cell Biology 4021 26% 0% 443
4 Genetics & Heredity 3780 20% 0% 350
5 Biochemistry & Molecular Biology 1355 26% 0% 453
6 Developmental Biology 449 4% 0% 62
7 Pathology 68 3% 0% 43
8 Cell & Tissue Engineering 49 1% 0% 10
9 Medicine, Research & Experimental 34 3% 0% 50
10 Biophysics 23 3% 0% 43

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOGENESIS DEV SECT 74139 1% 38% 11
2 BIOCHEM MOL BIOL F7 26 35544 0% 100% 2
3 ORAL SCI DENTYONSEI BIOTECHNOL 35544 0% 100% 2
4 SURG PHYSIOL DIGEST SYSTKAMIGYO KU 35544 0% 100% 2
5 VIRAL ONCOL 30137 1% 7% 25
6 CELL REGULATSAKYO KU 26655 0% 50% 3
7 MOL ASPECTS HEMATOPOIESIS 25583 0% 24% 6
8 HEMATOL MALIGNANCY TREATMENT 23695 0% 67% 2
9 IL RI EDUC 23695 0% 67% 2
10 UVA HLTH SCI 23695 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER GENETICS AND CYTOGENETICS 30849 6% 2% 103
2 LEUKEMIA 14989 5% 1% 80
3 BLOOD 12963 9% 0% 159
4 ONCOGENE 8783 6% 1% 95
5 BLOOD CELLS MOLECULES AND DISEASES 5730 1% 1% 24
6 GENES CHROMOSOMES & CANCER 5696 2% 1% 32
7 CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION 3698 1% 2% 10
8 MOLECULAR AND CELLULAR BIOLOGY 3182 4% 0% 64
9 INTERNATIONAL JOURNAL OF HEMATOLOGY 3146 2% 1% 26
10 LEUKEMIA RESEARCH 2962 2% 1% 32

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 RUNX3 1346360 8% 57% 134 Search RUNX3 Search RUNX3
2 AML1 ETO 916481 4% 68% 76 Search AML1+ETO Search AML1+ETO
3 RUNX1 894285 7% 43% 117 Search RUNX1 Search RUNX1
4 AML1 696603 4% 56% 70 Search AML1 Search AML1
5 RUNX 539586 3% 53% 57 Search RUNX Search RUNX
6 T821 360300 2% 48% 42 Search T821 Search T821
7 T8 21 313492 1% 84% 21 Search T8+21 Search T8+21
8 INV16 244991 2% 48% 29 Search INV16 Search INV16
9 CBF BETA MYH11 223301 1% 74% 17 Search CBF+BETA+MYH11 Search CBF+BETA+MYH11
10 CBF BETA 206944 1% 61% 19 Search CBF+BETA Search CBF+BETA

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LICHT, JD , (2001) AML1 AND THE AML1-ETO FUSION PROTEIN IN THE PATHOGENESIS OF T(8;21) AML.ONCOGENE. VOL. 20. ISSUE 40. P. 5660-5679 163 80% 95
2 LAM, K , ZHANG, DE , (2012) RUNX1 AND RUNX1-ETO: ROLES IN HEMATOPOIESIS AND LEUKEMOGENESIS.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 17. ISSUE . P. 1120-1139 120 70% 43
3 ITO, Y , BAE, SC , CHUANG, LSH , (2015) THE RUNX FAMILY: DEVELOPMENTAL REGULATORS IN CANCER.NATURE REVIEWS CANCER. VOL. 15. ISSUE 2. P. 81 -95 97 51% 37
4 DE BRAEKELEER, E , DOUET-GUILBERT, N , MOREL, F , LE BRIS, MJ , FEREC, C , DE BRAEKELEER, M , (2011) RUNX1 TRANSLOCATIONS AND FUSION GENES IN MALIGNANT HEMOPATHIES.FUTURE ONCOLOGY. VOL. 7. ISSUE 1. P. 77-91 93 74% 24
5 PETERSON, LF , ZHANG, DE , (2004) THE 8; 21 TRANSLOCATION IN LEUKEMOGENESIS.ONCOGENE. VOL. 23. ISSUE 24. P. 4255-4262 88 80% 174
6 MARKOVA, EN , PETROVA, NV , RAZIN, SV , KANTIDZE, OL , (2012) TRANSCRIPTION FACTOR RUNX1.MOLECULAR BIOLOGY. VOL. 46. ISSUE 6. P. 755-767 92 73% 0
7 ASOU, N , (2003) THE ROLE OF A RUNT DOMAIN TRANSCRIPTION FACTOR AML1/RUNX1 IN LEUKEMOGENESIS AND ITS CLINICAL IMPLICATIONS.CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. VOL. 45. ISSUE 2. P. 129-150 142 54% 35
8 BLYTH, K , CAMERON, ER , NEIL, JC , (2005) THE RUNX GENES: GAIN OR LOSS OF FUNCTION IN CANCER.NATURE REVIEWS CANCER. VOL. 5. ISSUE 5. P. 376-387 95 53% 264
9 DOWNING, JR , (1999) THE AML1-ETO CHIMAERIC TRANSCRIPTION FACTOR IN ACUTE MYELOID LEUKAEMIA: BIOLOGY AND CLINICAL SIGNIFICANCE.BRITISH JOURNAL OF HAEMATOLOGY. VOL. 106. ISSUE 2. P. 296-308 91 72% 128
10 ICHIKAWA, M , YOSHIMI, A , NAKAGAWA, M , NISHIMOTO, N , WATANABE-OKOCHI, N , KUROKAWA, M , (2013) A ROLE FOR RUNX1 IN HEMATOPOIESIS AND MYELOID LEUKEMIA.INTERNATIONAL JOURNAL OF HEMATOLOGY. VOL. 97. ISSUE 6. P. 726-734 58 78% 26

Classes with closest relation at Level 1


Rank Class id link
1 7164 RUNX2//CLEIDOCRANIAL DYSPLASIA//CBFA1
2 7627 TEL AML1//TEL//ETV6
3 16735 EVI1//EVI 1//RIZ1
4 552 ACUTE MYELOID LEUKEMIA//FLT3//FLT3 ITD
5 31489 TRISOMY 4//ACUTE MYELOID LEUKAEMIA LYMPHOPROLIFERATIVE DISORDERS//B L V
6 5973 MLL//MLL GENE//11Q23
7 19585 PU1//SFPI1 PU1//RADIATION INDUCED AML
8 4109 HEMANGIOBLAST//HEMOGENIC ENDOTHELIUM//HEMATOPOIESIS
9 30554 GFI1B//GFI1//ZELLBIOL TUMORFOR
10 27965 PRH//GROUCHO//PROLINE RICH HOMEODOMAIN PRH

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