Class information for:
Level 1: ASYMMETRIC DIMETHYLARGININE//ADMA//DIMETHYLARGININE DIMETHYLAMINOHYDROLASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4743 1734 41.1 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
630 3       HEPATIC ENCEPHALOPATHY//ASYMMETRIC DIMETHYLARGININE//HYPERAMMONEMIA 13067
2078 2             ASYMMETRIC DIMETHYLARGININE//ARGINASE//ADMA 5239
4743 1                   ASYMMETRIC DIMETHYLARGININE//ADMA//DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1734

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ASYMMETRIC DIMETHYLARGININE authKW 5658576 28% 66% 488
2 ADMA authKW 3382667 16% 68% 281
3 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE authKW 1679931 6% 89% 107
4 SYMMETRIC DIMETHYLARGININE authKW 846173 3% 83% 58
5 ASYMMETRIC DIMETHYLARGININE ADMA authKW 802363 3% 76% 60
6 DIMETHYLARGININE authKW 686931 3% 74% 53
7 DDAH authKW 636702 3% 80% 45
8 ASYMMETRICAL DIMETHYLARGININE authKW 418436 2% 61% 39
9 SDMA authKW 400539 3% 39% 59
10 METHYLARGININES authKW 331767 2% 61% 31

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Peripheral Vascular Diseases 5320 17% 0% 290
2 Urology & Nephrology 2655 12% 0% 208
3 Cardiac & Cardiovascular System 2094 15% 0% 254
4 Medical Laboratory Technology 997 4% 0% 73
5 Endocrinology & Metabolism 558 8% 0% 140
6 Medicine, Research & Experimental 454 7% 0% 124
7 Pharmacology & Pharmacy 295 10% 0% 176
8 Transplantation 215 3% 0% 47
9 Biochemistry & Molecular Biology 195 13% 0% 232
10 Physiology 190 5% 0% 80

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NITR OXIDE SIGNALLING GRP 90554 0% 86% 6
2 UNIV VASC MED 88762 1% 46% 11
3 EXPT CLIN PHARMACOLCLIN PHARMACOL UNIT 70432 0% 100% 4
4 IDEXX BIOTECHNOL GRP 52824 0% 100% 3
5 TRANSLAT BIOMED SCI 48144 1% 11% 26
6 ARBEITSGRP KLIN PHARMAKOL 46952 0% 67% 4
7 BIOSYST REGULATCHIYODA KU 46952 0% 67% 4
8 HLTH PROMOT FAMILY CARE 42252 0% 40% 6
9 MED CELLULAR MOLEC SCI 39617 0% 75% 3
10 SCI MENTAL HLTH ADVERS UNIT 39617 0% 75% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 VASCULAR MEDICINE 9440 1% 3% 21
2 AMINO ACIDS 7073 2% 1% 38
3 ATHEROSCLEROSIS SUPPLEMENTS 5132 1% 3% 9
4 NITRIC OXIDE-BIOLOGY AND CHEMISTRY 4637 1% 1% 19
5 ATHEROSCLEROSIS 2463 2% 0% 39
6 VASCULAR PHARMACOLOGY 1867 1% 1% 11
7 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 1803 2% 0% 28
8 NEPHROLOGY DIALYSIS TRANSPLANTATION 1592 2% 0% 34
9 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 1451 2% 0% 32
10 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1415 2% 0% 28

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ASYMMETRIC DIMETHYLARGININE 5658576 28% 66% 488 Search ASYMMETRIC+DIMETHYLARGININE Search ASYMMETRIC+DIMETHYLARGININE
2 ADMA 3382667 16% 68% 281 Search ADMA Search ADMA
3 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1679931 6% 89% 107 Search DIMETHYLARGININE+DIMETHYLAMINOHYDROLASE Search DIMETHYLARGININE+DIMETHYLAMINOHYDROLASE
4 SYMMETRIC DIMETHYLARGININE 846173 3% 83% 58 Search SYMMETRIC+DIMETHYLARGININE Search SYMMETRIC+DIMETHYLARGININE
5 ASYMMETRIC DIMETHYLARGININE ADMA 802363 3% 76% 60 Search ASYMMETRIC+DIMETHYLARGININE+ADMA Search ASYMMETRIC+DIMETHYLARGININE+ADMA
6 DIMETHYLARGININE 686931 3% 74% 53 Search DIMETHYLARGININE Search DIMETHYLARGININE
7 DDAH 636702 3% 80% 45 Search DDAH Search DDAH
8 ASYMMETRICAL DIMETHYLARGININE 418436 2% 61% 39 Search ASYMMETRICAL+DIMETHYLARGININE Search ASYMMETRICAL+DIMETHYLARGININE
9 SDMA 400539 3% 39% 59 Search SDMA Search SDMA
10 METHYLARGININES 331767 2% 61% 31 Search METHYLARGININES Search METHYLARGININES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 TOUSOULIS, D , GEORGAKIS, MK , OIKONOMOU, E , PAPAGEORGIOU, N , ZAROMITIDOU, M , LATSIOS, G , PAPAIOANNOU, S , SIASOS, G , (2015) ASYMMETRIC DIMETHYLARGININE: CLINICAL SIGNIFICANCE AND NOVEL THERAPEUTIC APPROACHES.CURRENT MEDICINAL CHEMISTRY. VOL. 22. ISSUE 24. P. 2871 -2901 217 63% 1
2 BOURAS, G , DEFTEREOS, S , TOUSOULIS, D , GIANNOPOULOS, G , CHATZIS, G , TSOUNIS, D , CLEMAN, MW , STEFANADIS, C , (2013) ASYMMETRIC DIMETHYLARGININE (ADMA): A PROMISING BIOMARKER FOR CARDIOVASCULAR DISEASE?.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 13. ISSUE 2. P. 180-200 149 76% 29
3 CAPLIN, B , LEIPER, J , (2012) ENDOGENOUS NITRIC OXIDE SYNTHASE INHIBITORS IN THE BIOLOGY OF DISEASE MARKERS, MEDIATORS, AND REGULATORS?.ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. VOL. 32. ISSUE 6. P. 1343 -+ 128 77% 37
4 SCHWEDHELM, E , BOGER, RH , (2011) THE ROLE OF ASYMMETRIC AND SYMMETRIC DIMETHYLARGININES IN RENAL DISEASE.NATURE REVIEWS NEPHROLOGY. VOL. 7. ISSUE 5. P. 275-285 104 87% 81
5 BLACKWELL, S , (2010) THE BIOCHEMISTRY, MEASUREMENT AND CURRENT CLINICAL SIGNIFICANCE OF ASYMMETRIC DIMETHYLARGININE.ANNALS OF CLINICAL BIOCHEMISTRY. VOL. 47. ISSUE . P. 17-28 110 90% 33
6 PALM, F , ONOZATO, ML , LUO, ZM , WILCOX, CS , (2007) DIMETHYLARGININE DIMETHYLAMINOHYDROLASE (DDAH): EXPRESSION, REGULATION, AND FUNCTION IN THE CARDIOVASCULAR AND RENAL SYSTEMS.AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. VOL. 293. ISSUE 6. P. H3227-H3245 131 62% 145
7 BELTOWSKI, J , KEDRA, A , (2006) ASYMMETRIC DIMETHYLARGININE (ADMA) AS A TARGET FOR PHARMACOTHERAPY.PHARMACOLOGICAL REPORTS. VOL. 58. ISSUE 2. P. 159-178 117 77% 86
8 CHEN, SF , LI, N , DEB-CHATTERJI, M , DONG, Q , KIELSTEIN, JT , WEISSENBORN, K , WORTHMANN, H , (2012) ASYMMETRIC DIMETHYARGININE AS MARKER AND MEDIATOR IN ISCHEMIC STROKE.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. VOL. 13. ISSUE 12. P. 15983-16004 97 83% 24
9 LEIPER, J , NANDI, M , (2011) THE THERAPEUTIC POTENTIAL OF TARGETING ENDOGENOUS INHIBITORS OF NITRIC OXIDE SYNTHESIS.NATURE REVIEWS DRUG DISCOVERY. VOL. 10. ISSUE 4. P. 277 -291 118 63% 66
10 ARRIGONI, F , AHMETAJ, B , LEIPER, J , (2010) THE BIOLOGY AND THERAPEUTIC POTENTIAL OF THE DDAH/ADMA PATHWAY.CURRENT PHARMACEUTICAL DESIGN. VOL. 16. ISSUE 37. P. 4089 -4102 125 59% 16

Classes with closest relation at Level 1


Rank Class id link
1 32976 ALANYA HASTANESI//BACKGROUND DISEASE//BAXTER NOVUM RENAL DIS
2 7582 L ARGININE//HYPERCHOLESTEROLEMIA//REGENERATED ENDOTHELIUM
3 7846 ARGINASE//ARGINASE II//ARGINASE INHIBITORS
4 10658 CITRULLINE//HUBEI ANIM NUTR FEED SCI//SUBTROP AGR
5 21473 GUANIDINO COMPOUNDS//METHYLGUANIDINE//GUANIDINOSUCCINIC ACID
6 4838 NORMAL PATHOL PHYSIOL//NITRIC OXIDE//L NAME
7 4046 FLOW MEDIATED DILATION//ENDOTHELIAL FUNCTION//FLOW MEDIATED DILATATION
8 20336 NEBIVOLOL//NEBIVOLOL HYDROCHLORIDE//THIRD GENERATION BETA BLOCKERS
9 5481 ARGININE METHYLATION//PROTEIN ARGININE METHYLTRANSFERASE//PRMT
10 23814 ARGININE DEIMINASE//ARGININE DEPRIVATION//ARGININOSUCCINATE SYNTHETASE

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