Class information for:
Level 1: P73//P63//EEC SYNDROME

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4381 1795 44.4 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
304 3       P53//RETINOBLASTOMA//MDM2 40663
936 2             P53//MDM2//P73 10991
4381 1                   P73//P63//EEC SYNDROME 1795

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 P73 authKW 3933311 21% 61% 382
2 P63 authKW 2703908 22% 41% 387
3 EEC SYNDROME authKW 604777 2% 89% 40
4 P53 FAMILY authKW 489838 3% 60% 48
5 TP63 authKW 370447 2% 66% 33
6 TAP73 authKW 322139 1% 76% 25
7 DELTA NP73 authKW 316634 1% 85% 22
8 RAPP HODGKIN SYNDROME authKW 255144 1% 100% 15
9 DELTA NP63 authKW 243112 2% 53% 27
10 DNP73 authKW 170096 1% 100% 10

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 8036 35% 0% 624
2 Oncology 6224 31% 0% 563
3 Genetics & Heredity 2429 16% 0% 293
4 Biochemistry & Molecular Biology 2110 31% 0% 556
5 Dermatology 841 6% 0% 102
6 Pathology 691 6% 0% 111
7 Developmental Biology 297 3% 0% 53
8 Biophysics 209 5% 0% 90
9 Medicine, Research & Experimental 85 4% 0% 68
10 Pediatrics 44 3% 0% 50

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IDI IRCCS 149297 1% 34% 26
2 TOXICOL UNIT 143104 6% 7% 116
3 BIOCHEM IDI IRCCS 103419 1% 41% 15
4 INSERTECH 64028 0% 47% 8
5 BIOCHEM IDI IRCC 60746 0% 71% 5
6 EXPT MED SURG 57226 2% 8% 41
7 CANC CANC THER Y 54421 0% 40% 8
8 MOL TUMOR BIOL GRP 51029 0% 100% 3
9 IDIBIOCHEM 42519 0% 50% 5
10 INTERNAL MED HEPATOL GASTROENTEROL 4 42519 0% 50% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 22556 5% 2% 81
2 CELL DEATH AND DIFFERENTIATION 13918 3% 2% 51
3 ONCOGENE 9889 6% 1% 103
4 CELL DEATH & DISEASE 3779 1% 1% 23
5 AGING-US 2255 1% 1% 11
6 PEDIATRIC DERMATOLOGY 2193 1% 1% 22
7 AMERICAN JOURNAL OF MEDICAL GENETICS PART A 1950 1% 0% 26
8 CANCER RESEARCH 1530 3% 0% 61
9 ONCOTARGET 1456 2% 0% 33
10 CELL CYCLE 920 0% 1% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 P73 3933311 21% 61% 382 Search P73 Search P73
2 P63 2703908 22% 41% 387 Search P63 Search P63
3 EEC SYNDROME 604777 2% 89% 40 Search EEC+SYNDROME Search EEC+SYNDROME
4 P53 FAMILY 489838 3% 60% 48 Search P53+FAMILY Search P53+FAMILY
5 TP63 370447 2% 66% 33 Search TP63 Search TP63
6 TAP73 322139 1% 76% 25 Search TAP73 Search TAP73
7 DELTA NP73 316634 1% 85% 22 Search DELTA+NP73 Search DELTA+NP73
8 RAPP HODGKIN SYNDROME 255144 1% 100% 15 Search RAPP+HODGKIN+SYNDROME Search RAPP+HODGKIN+SYNDROME
9 DELTA NP63 243112 2% 53% 27 Search DELTA+NP63 Search DELTA+NP63
10 DNP73 170096 1% 100% 10 Search DNP73 Search DNP73

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 DEYOUNG, MP , ELLISEN, LW , (2007) P63 AND P73 IN HUMAN CANCER: DEFINING THE NETWORK.ONCOGENE. VOL. 26. ISSUE 36. P. 5169-5183 128 84% 141
2 MOLL, UM , SLADE, N , (2004) P63 AND P73: ROLES IN DEVELOPMENT AND TUMOR FORMATION.MOLECULAR CANCER RESEARCH. VOL. 2. ISSUE 7. P. 371-386 131 79% 312
3 ORZOL, P , HOLCAKOVA, J , NEKULOVA, M , NENUTIL, R , VOJTESEK, B , COATES, PJ , (2015) THE DIVERSE ONCOGENIC AND TUMOUR SUPPRESSOR ROLES OF P63 AND P73 IN CANCER: A REVIEW BY CANCER SITE.HISTOLOGY AND HISTOPATHOLOGY. VOL. 30. ISSUE 5. P. 503 -521 147 65% 4
4 COSTANZO, A , PEDICONI, N , NARCISI, A , GUERRIERI, F , BELLONI, L , FAUSTI, F , BOTTI, E , LEVRERO, M , (2014) TP63 AND TP73 IN CANCER, AN UNRESOLVED "FAMILY" PUZZLE OF COMPLEXITY, REDUNDANCY AND HIERARCHY.FEBS LETTERS. VOL. 588. ISSUE 16. P. 2590 -2599 121 71% 12
5 MELINO, G , (2011) P63 IS A SUPPRESSOR OF TUMORIGENESIS AND METASTASIS INTERACTING WITH MUTANT P53.CELL DEATH AND DIFFERENTIATION. VOL. 18. ISSUE 9. P. 1487 -1499 91 78% 98
6 VILGELM, A , EL-RIFAI, W , ZAIKA, A , (2008) THERAPEUTIC PROSPECTS FOR P73 AND P63: RISING FROM THE SHADOW OF P53.DRUG RESISTANCE UPDATES. VOL. 11. ISSUE 4-5. P. 152-163 113 81% 41
7 MELINO, G , DE LAURENZI, V , VOUSDEN, KH , (2002) P73: FRIEND OR FOE IN TUMORIGENESIS.NATURE REVIEWS CANCER. VOL. 2. ISSUE 8. P. 605-615 97 80% 385
8 MULLER, M , SCHLEITHOFF, ES , STREMMEL, W , MELINO, G , KRAMMER, PH , SCHILLING, T , (2006) ONE, TWO, THREE - P53, P63, P73 AND CHEMOSENSITIVITY.DRUG RESISTANCE UPDATES. VOL. 9. ISSUE 6. P. 288 -306 126 71% 68
9 CANDI, E , AGOSTINI, M , MELINO, G , BERNASSOLA, F , (2014) HOW THE TP53 FAMILY PROTEINS TP63 AND TP73 CONTRIBUTE TO TUMORIGENESIS: REGULATORS AND EFFECTORS.HUMAN MUTATION. VOL. 35. ISSUE 6. P. 702 -714 99 66% 29
10 SLADE, N , HORVAT, A , (2011) TARGETING P73-A POTENTIAL APPROACH IN CANCER TREATMENT.CURRENT PHARMACEUTICAL DESIGN. VOL. 17. ISSUE 6. P. 591-602 108 78% 3

Classes with closest relation at Level 1


Rank Class id link
1 8010 MUTANT P53//PRIMA 1//CP 31398
2 31291 IASPP//ASPP2//53BP2
3 1860 MDM2//MDMX//MDM4
4 12934 ECTRODACTYLY//ROBERTS SYNDROME//TIBIAL HEMIMELIA
5 30791 PUMA//PUMA GENE//P53 UPREGULATED MODULATOR OF APOPTOSIS PUMA
6 9053 P53 POLYMORPHISM//P53 CODON 72//CODON 72
7 27524 DISSEMINATED NEOPLASIA//HAEMIC NEOPLASIA//MYA ARENARIA
8 22610 WWP1//WW DOMAIN//CKIP 1
9 5756 HYPODONTIA//ECTODERMAL DYSPLASIA//OLIGODONTIA
10 1581 P53//P53 GENE//ONCOGENE

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