Class information for:
Level 1: SARPOGRELATE//5 HT1 LIKE RECEPTORS//KETANSERIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3791 1906 31.2 66%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
76 3       NEUROSCIENCES//DOPAMINE//SEROTONIN 81359
218 2             SEROTONIN//5 HT1A RECEPTOR//5 HT2A RECEPTOR 20633
3791 1                   SARPOGRELATE//5 HT1 LIKE RECEPTORS//KETANSERIN 1906

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SARPOGRELATE authKW 830525 3% 81% 64
2 5 HT1 LIKE RECEPTORS authKW 328134 1% 79% 26
3 KETANSERIN authKW 267153 4% 20% 85
4 SB224289 authKW 142476 1% 68% 13
5 SUMATRIPTAN authKW 132458 4% 11% 78
6 GR127935 authKW 128119 1% 33% 24
7 5 HYDROXYTRYPTAMINE authKW 107321 6% 6% 106
8 BRL15572 authKW 102518 0% 80% 8
9 SARPOGRELATE HYDROCHLORIDE authKW 102006 1% 58% 11
10 DUTCH MIGRAINE GRP address 87211 0% 78% 7

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Pharmacology & Pharmacy 22846 63% 0% 1201
2 Cardiac & Cardiovascular System 3640 18% 0% 344
3 Peripheral Vascular Diseases 2139 10% 0% 199
4 Physiology 370 6% 0% 110
5 Medicine, Research & Experimental 187 5% 0% 93
6 Chemistry, Medicinal 127 3% 0% 61
7 Hematology 100 3% 0% 58
8 Toxicology 51 2% 0% 45
9 Anesthesiology 39 1% 0% 23
10 CYTOLOGY & HISTOLOGY 27 0% 0% 4

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DUTCH MIGRAINE GRP 87211 0% 78% 7
2 FARMACOGNOSIA FARMACOL 84262 1% 48% 11
3 SECC TER EUT EXPT 50045 1% 31% 10
4 ENCB FISIOL 32038 0% 100% 2
5 ESM FISIOL FARMACOL 32038 0% 100% 2
6 MED HLTH SCI PHARMACOL POB 1738 32038 0% 100% 2
7 CARDIOVASC COEUR 17722 1% 9% 12
8 BASIC ALLIED SCI 16019 0% 100% 1
9 BETH ISRAEL DEACONESS MED LIFE SCIMED SC 16019 0% 100% 1
10 BIOL RECEPTOR PHARMACOL GRP 16019 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 52010 10% 2% 189
2 BRITISH JOURNAL OF PHARMACOLOGY 12684 6% 1% 119
3 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 11442 3% 1% 66
4 EUROPEAN JOURNAL OF PHARMACOLOGY 11210 7% 1% 141
5 ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE 10188 2% 2% 38
6 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 9256 6% 1% 111
7 JOURNAL OF AUTONOMIC PHARMACOLOGY 4856 1% 2% 16
8 JOURNAL OF HYPERTENSION 4409 3% 1% 52
9 CLINICAL PHYSIOLOGY AND BIOCHEMISTRY 3219 0% 3% 8
10 BLOOD VESSELS 3218 0% 2% 9

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SARPOGRELATE 830525 3% 81% 64 Search SARPOGRELATE Search SARPOGRELATE
2 5 HT1 LIKE RECEPTORS 328134 1% 79% 26 Search 5+HT1+LIKE+RECEPTORS Search 5+HT1+LIKE+RECEPTORS
3 KETANSERIN 267153 4% 20% 85 Search KETANSERIN Search KETANSERIN
4 SB224289 142476 1% 68% 13 Search SB224289 Search SB224289
5 SUMATRIPTAN 132458 4% 11% 78 Search SUMATRIPTAN Search SUMATRIPTAN
6 GR127935 128119 1% 33% 24 Search GR127935 Search GR127935
7 5 HYDROXYTRYPTAMINE 107321 6% 6% 106 Search 5+HYDROXYTRYPTAMINE Search 5+HYDROXYTRYPTAMINE
8 BRL15572 102518 0% 80% 8 Search BRL15572 Search BRL15572
9 SARPOGRELATE HYDROCHLORIDE 102006 1% 58% 11 Search SARPOGRELATE+HYDROCHLORIDE Search SARPOGRELATE+HYDROCHLORIDE
10 AT 1015 80094 0% 100% 5 Search AT+1015 Search AT+1015

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 VANHOUTTE, P , AMERY, A , BIRKENHAGER, W , BRECKENRIDGE, A , BUHLER, F , DISTLER, A , DORMANDY, J , DOYLE, A , FROHLICH, E , HANSSON, L , ET AL (1988) SEROTONINERGIC MECHANISMS IN HYPERTENSION - FOCUS ON THE EFFECTS OF KETANSERIN.HYPERTENSION. VOL. 11. ISSUE 2. P. 111-133 182 84% 99
2 FRISHMAN, WH , HUBERFELD, S , OKIN, S , WANG, YH , KUMAR, A , SHAREEF, B , (1995) SEROTONIN AND SEROTONIN ANTAGONISM IN CARDIOVASCULAR AND NON-CARDIOVASCULAR DISEASE.JOURNAL OF CLINICAL PHARMACOLOGY. VOL. 35. ISSUE 6. P. 541-572 132 84% 65
3 WATTS, SW , MORRISON, SF , DAVIS, RP , BARMAN, SM , (2012) SEROTONIN AND BLOOD PRESSURE REGULATION.PHARMACOLOGICAL REVIEWS. VOL. 64. ISSUE 2. P. 359 -388 148 38% 60
4 BROGDEN, RN , SORKIN, EM , (1990) KETANSERIN - A REVIEW OF ITS PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES, AND THERAPEUTIC POTENTIAL IN HYPERTENSION AND PERIPHERAL VASCULAR-DISEASE.DRUGS. VOL. 40. ISSUE 6. P. 903 -949 174 75% 56
5 FRISHMAN, WH , GREWALL, P , (2000) SEROTONIN AND THE HEART.ANNALS OF MEDICINE. VOL. 32. ISSUE 3. P. 195 -209 83 72% 70
6 DISTLER, A , (1990) CLINICAL ASPECTS DURING THERAPY WITH THE SEROTONIN ANTAGONIST KETANSERIN.CLINICAL PHYSIOLOGY AND BIOCHEMISTRY. VOL. 8. ISSUE . P. 64-80 92 96% 4
7 VILLALON, CM , CENTURION, D , (2007) CARDIOVASCULAR RESPONSES PRODUCED BY 5-HYDROXYTRIPTAMINE: A PHARMACOLOGICAL UPDATE ON THE RECEPTORS/MECHANISMS INVOLVED AND THERAPEUTIC IMPLICATIONS.NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. VOL. 376. ISSUE 1-2. P. 45-63 73 51% 90
8 MARTIN, GR , (1994) VASCULAR RECEPTORS FOR 5-HYDROXYTRYPTAMINE - DISTRIBUTION, FUNCTION AND CLASSIFICATION.PHARMACOLOGY & THERAPEUTICS. VOL. 62. ISSUE 3. P. 283-324 90 58% 128
9 FRISHMAN, WH , OKIN, S , HUBERFELD, S , (1988) SEROTONIN ANTAGONISM IN THE TREATMENT OF SYSTEMIC HYPERTENSION - THE ROLE OF KETANSERIN.MEDICAL CLINICS OF NORTH AMERICA. VOL. 72. ISSUE 2. P. 501-522 82 100% 8
10 SAINI, HK , TAKEDA, N , GOYAL, RK , KUMAMOTO, H , ARNEJA, AS , DHALLA, NS , (2004) THERAPEUTIC POTENTIALS OF SARPOGRELATE IN CARDIOVASCULAR DISEASE.CARDIOVASCULAR DRUG REVIEWS. VOL. 22. ISSUE 1. P. 27-54 68 50% 45

Classes with closest relation at Level 1


Rank Class id link
1 20134 URAPIDIL//PHARMACOLOGY URAPIDIL//URAPIDIL HYDROCHLORIDE
2 11921 5 HT1B RECEPTOR//5 HT MODULINE//UNITE PHARMACOL NEUROIMMUNOENDOCRINIENNE
3 3578 5 HT2C RECEPTOR//5 HT2A RECEPTOR//5 HT2C
4 26532 AGONIST AFFINITY//ANTAGONIST DISSOCIATION CONSTANTS//IRREVERSIBLE RECEPTOR INACTIVATION METHOD
5 17506 5 6 TRANS PROSTAGLANDIN E2//IN VITRO THROMBOLYSIS//REOCCLUSION AFTER THROMBOLYSIS
6 5208 JOURNAL OF AUTONOMIC PHARMACOLOGY//POSTJUNCTIONAL ALPHA 2 ADRENOCEPTORS//POSTJUNCTIONAL ALPHA 1 ADRENOCEPTORS
7 27114 BLEEDING ABNORMALITIES//SELECTIVE SEROTONIN REUPTAKE INHIBITORS//ANTICOAGULATION MEDICATION
8 2928 TRIPTANS//SUMATRIPTAN//MIGRAINE
9 28636 COLD INDUCED HYPERTENSION//AT1 RECEPTOR ANTISENSE//HYPERTENSION 2K1C
10 3828 ENDOTHELIUM DERIVED RELAXING FACTOR//EDRF//N G NITRO L ARGININE

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