Class information for:
Level 1: BENZARONE//BENZBROMARONE METABOLISM//FULMINANT HEPATITIS CIRRHOSIS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
35437 97 21.4 33%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
14 4 ORTHOPEDICS//DENTISTRY, ORAL SURGERY & MEDICINE//SPORT SCIENCES 808941
580 3       ACUPUNCTURE//INTEGRATIVE & COMPLEMENTARY MEDICINE//COMPLEMENTARY AND ALTERNATIVE MEDICINE 16156
3254 2             PLACEBO EFFECT//PLACEBO//NOCEBO 1973
35437 1                   BENZARONE//BENZBROMARONE METABOLISM//FULMINANT HEPATITIS CIRRHOSIS 97

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BENZARONE authKW 629601 2% 100% 2
2 BENZBROMARONE METABOLISM authKW 314800 1% 100% 1
3 FULMINANT HEPATITIS CIRRHOSIS authKW 314800 1% 100% 1
4 SLOW ELIMINATION PHENOTYPES authKW 314800 1% 100% 1
5 BENZBROMARONE authKW 296627 7% 13% 7
6 BIO CHEMOTHERAPY authKW 78699 1% 25% 1
7 WUYA INNOVAT address 78699 1% 25% 1
8 DEV THER EUTSEATTLE CHILDRENS address 52465 1% 17% 1
9 PHARMACEUT GUIZHOU PROV address 44970 1% 14% 1
10 URICOSURIC EFFECT authKW 44970 1% 14% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 234 30% 0% 29
2 Chemistry, Medicinal 128 11% 0% 11
3 Toxicology 102 10% 0% 10
4 Medicine, General & Internal 92 15% 0% 15
5 Urology & Nephrology 85 9% 0% 9
6 Pathology 37 6% 0% 6
7 Peripheral Vascular Diseases 34 6% 0% 6
8 Radiology, Nuclear Medicine & Medical Imaging 23 7% 0% 7
9 Gastroenterology & Hepatology 20 5% 0% 5
10 Chemistry, Analytical 17 7% 0% 7

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 WUYA INNOVAT 78699 1% 25% 1
2 DEV THER EUTSEATTLE CHILDRENS 52465 1% 17% 1
3 PHARMACEUT GUIZHOU PROV 44970 1% 14% 1
4 NAT PHARMACEUT CHEM 28616 1% 9% 1
5 HEMATOL MED ONCOL L A SERAGNOLI 11657 1% 4% 1
6 IMMUNOTHER Y UNIT 7153 1% 2% 1
7 POLICLIN ST ORSOLA MALPIGHI 2860 1% 1% 1
8 STRUCT BASED DRUG DESIGN DISCOVERY 2091 2% 0% 2
9 SECT 1 916 1% 0% 1
10 PHARMACOKINET 340 1% 0% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ACTA RADIOLOGICA-DIAGNOSIS 8103 4% 1% 4
2 ACTA PATHOLOGICA MICROBIOLOGICA ET IMMUNOLOGICA SCANDINAVICA SECTION A-PATHOLOGY 7610 3% 1% 3
3 ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH 3507 7% 0% 7
4 FUNKTIONELLE BIOLOGIE & MEDIZIN 3146 1% 1% 1
5 KLINISCHE WOCHENSCHRIFT 1963 4% 0% 4
6 DRUG METABOLISM AND PHARMACOKINETICS 1742 2% 0% 2
7 EXPERIMENTAL PATHOLOGY 1702 2% 0% 2
8 ADVANCES IN INTERNAL MEDICINE 1621 1% 1% 1
9 INNERE MEDIZIN 1379 1% 0% 1
10 PERITONEAL DIALYSIS BULLETIN 1233 1% 0% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BENZARONE 629601 2% 100% 2 Search BENZARONE Search BENZARONE
2 BENZBROMARONE METABOLISM 314800 1% 100% 1 Search BENZBROMARONE+METABOLISM Search BENZBROMARONE+METABOLISM
3 FULMINANT HEPATITIS CIRRHOSIS 314800 1% 100% 1 Search FULMINANT+HEPATITIS+CIRRHOSIS Search FULMINANT+HEPATITIS+CIRRHOSIS
4 SLOW ELIMINATION PHENOTYPES 314800 1% 100% 1 Search SLOW+ELIMINATION+PHENOTYPES Search SLOW+ELIMINATION+PHENOTYPES
5 BENZBROMARONE 296627 7% 13% 7 Search BENZBROMARONE Search BENZBROMARONE
6 BIO CHEMOTHERAPY 78699 1% 25% 1 Search BIO+CHEMOTHERAPY Search BIO+CHEMOTHERAPY
7 URICOSURIC EFFECT 44970 1% 14% 1 Search URICOSURIC+EFFECT Search URICOSURIC+EFFECT
8 DRUG INDUCED HEPATIC INJURY 39348 1% 13% 1 Search DRUG+INDUCED+HEPATIC+INJURY Search DRUG+INDUCED+HEPATIC+INJURY
9 DRUG INDUCED LIVER TOXICITY 28616 1% 9% 1 Search DRUG+INDUCED+LIVER+TOXICITY Search DRUG+INDUCED+LIVER+TOXICITY
10 HPLC QTOF MS 17487 1% 6% 1 Search HPLC+QTOF+MS Search HPLC+QTOF+MS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 WU, HQ , PENG, Y , WANG, SJ , WANG, K , ZHAO, XC , JIANG, F , (2012) METABOLISM STUDIES OF BENZBROMARONE IN RATS BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRY.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 911. ISSUE . P. 122-132 8 62% 2
2 DEVRIES, JX , WALTERSACK, I , ITTENSOHN, A , WEBER, E , EMPL, H , GRESSER, U , ZOLLNER, N , (1993) BENZBROMARONE HYDROXYLATION IN MAN - DEFECTIVE FORMATION OF THE 6-HYDROXYBENZBROMARONE METABOLITE.CLINICAL INVESTIGATOR. VOL. 71. ISSUE 11. P. 947-952 8 89% 4
3 WALTERSACK, I , DEVRIES, JX , ITTENSOHN, A , WEBER, E , (1990) RAPID AND SLOW BENZBROMARONE ELIMINATION PHENOTYPES IN MAN - BENZBROMARONE AND METABOLITE PROFILES.EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. VOL. 39. ISSUE 6. P. 577-581 8 89% 10
4 KOBAYASHI, K , CHIBA, K , OKA, H , ISHIKAWA, M , KAJIWARA, E , (2012) IDENTIFICATION OF CYP ISOZYMES INVOLVED IN BENZBROMARONE METABOLISM IN HUMAN LIVER MICROSOMES.BIOPHARMACEUTICS & DRUG DISPOSITION. VOL. 33. ISSUE 8. P. 466 -473 6 55% 7
5 TVEDEGAARD, E , (1987) ARTERIAL-DISEASE IN CHRONIC-RENAL-FAILURE - AN EXPERIMENTAL-STUDY IN THE RABBIT.ACTA PATHOLOGICA MICROBIOLOGICA ET IMMUNOLOGICA SCANDINAVICA SECTION A-PATHOLOGY. VOL. 95. ISSUE . P. 1-& 14 58% 1
6 VANDERKLAUW, MM , HOUTMAN, PM , STRICKER, BHC , SPOELSTRA, P , (1994) HEPATIC-INJURY CAUSED BY BENZBROMARONE.JOURNAL OF HEPATOLOGY. VOL. 20. ISSUE 3. P. 376-379 7 78% 31
7 DEVRIES, JX , WALTERSACK, I , VOSS, A , FORSTER, W , PONS, PI , STOETZER, F , SPRAUL, M , ACKERMANN, M , MOYNA, G , (1993) METABOLISM OF BENZBROMARONE IN MAN - STRUCTURES OF NEW OXIDATIVE METABOLITES, 6-HYDROXY-BENZBROMARONE AND 1'-OXO-BENZBROMARONE, AND THE ENANTIOSELECTIVE FORMATION AND ELIMINATION OF 1'-HYDROXYBENZBROMARONE.XENOBIOTICA. VOL. 23. ISSUE 12. P. 1435-1450 7 78% 10
8 GUMIENICZEK, A , PRZYBOROWSKI, L , (1994) DETERMINATION OF BENZBROMARONE AND BENZARONE IN PHARMACEUTICALS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY.JOURNAL OF LIQUID CHROMATOGRAPHY. VOL. 17. ISSUE 16. P. 3411-3419 5 100% 1
9 ARNOLD, PJ , GUSERLE, R , LUCKOW, V , HEMMER, R , GROTE, H , (1991) LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY IN METABOLIC RESEARCH .1. METABOLITES OF BENZBROMARONE IN HUMAN PLASMA AND URINE.JOURNAL OF CHROMATOGRAPHY. VOL. 554. ISSUE 1-2. P. 267-280 5 100% 3
10 KOBAYASHI, K , KAJIWARA, E , ISHIKAWA, M , MIMURA, H , OKA, H , EJIRI, Y , HOSODA, M , CHIBA, K , (2013) CYTOTOXIC EFFECTS OF BENZBROMARONE AND ITS 1 '-HYDROXY METABOLITE IN HUMAN HEPATOCARCINOMA FLC4 CELLS CULTURED ON MICRO-SPACE CELL CULTURE PLATES.DRUG METABOLISM AND PHARMACOKINETICS. VOL. 28. ISSUE 3. P. 265-268 5 36% 4

Classes with closest relation at Level 1


Rank Class id link
1 37600 PSYCHONEUROENDOCRINOL KRAEPEL R 10//MAGNESIUM-BULLETIN//ENDOCRINE NEOPLASIA
2 32386 ERYTHROCYTE DERIVED DEPRESSING FACTOR//NITRERGIC INNERVATION//ADENYLATE CYCLASE CYCLIC AMP SYSTEM
3 28818 HEPARG CELLS//HEPARG//NEOHEPATOCYTES
4 33058 VALUE COMMUNICATION//ABT NORMBILDUNG UMWELT//ARBEITBEREICH QUAL BILDUNGS SOZIALFOR UNG
5 29015 DIAGNOST COORDINATING//AGE SEX REGISTER//AMARINA MOTTA CLIN
6 31820 ALVERINE//THERAPIE//ASSOC FRANCAISE REGIONAUX PHARMACOVIGILANCE
7 1775 GOUT//FEBUXOSTAT//HYPERURICEMIA
8 18852 ACIDIC PH INDUCED CONTRACTION//CYTOSOLIC ALKALOSIS//RYANODINE SENSITIVE CALCIUM STORE
9 29518 ACEMETACIN//1 1 DIOXO 1 2 THIAZINE 6 CARBALDEHYDES//ACEMETACIN ACE
10 34055 BRAIN INJURY DERIVED NEUROTROPHIC PEPTIDE//MODIFIED RECALCIFICATION TIME TEST//NEURONS MYOTUBES

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