Class information for:
Level 1: PROTEIN KINASE C//PHORBOL ESTER//COW MAMMARY GLAND

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3210 2038 34.8 74%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
328 3       PHOSPHOLIPASE D//STIM1//REGUCALCIN 38118
1486 2             PROTEIN KINASE C//BRYOSTATIN//BRYOSTATIN 1 7631
3210 1                   PROTEIN KINASE C//PHORBOL ESTER//COW MAMMARY GLAND 2038

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROTEIN KINASE C authKW 101065 12% 3% 251
2 PHORBOL ESTER authKW 31737 3% 3% 61
3 COW MAMMARY GLAND authKW 29962 0% 100% 2
4 GAMMA SUBSPECIES authKW 29962 0% 100% 2
5 MINIST PUBL HLTH GLYCOCONJUGATES address 29962 0% 100% 2
6 PHORBOL ESTER RECEPTOR authKW 22469 0% 50% 3
7 PROTEIN KINASE C ISOZYMES authKW 18653 0% 14% 9
8 1 5 ISOQUINOLINYLSULPHONYL 2 METHYLPIPERAZINEH7 authKW 14981 0% 100% 1
9 1 OMEGA F 18FLUOROACYL 2 ACYLGLYCEROL authKW 14981 0% 100% 1
10 12 0 TETRA DECANOYL PHORBOL 13 ACETATE authKW 14981 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 7790 51% 0% 1048
2 Biophysics 6197 21% 0% 419
3 Cell Biology 1470 15% 0% 313
4 Neurosciences 791 14% 0% 280
5 Oncology 585 11% 0% 219
6 Pharmacology & Pharmacy 246 9% 0% 184
7 CYTOLOGY & HISTOLOGY 112 0% 0% 8
8 Developmental Biology 65 2% 0% 31
9 Biology 59 2% 0% 46
10 Medicine, Research & Experimental 21 2% 0% 50

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MINIST PUBL HLTH GLYCOCONJUGATES 29962 0% 100% 2
2 ALBERT B CHANDLER MED NEUROL 14981 0% 100% 1
3 BIOQUIM GRP BIOMED CSIC UNIDAD ASOCIADA 14981 0% 100% 1
4 COOPER DR 127 NEUROL 14981 0% 100% 1
5 GENET ADRIAN BLDG UNIV RD 14981 0% 100% 1
6 HAEMATOL MOLEC BIOL 14981 0% 100% 1
7 HLTH SCI BIOCHEM 1200 MAIN ST W 14981 0% 100% 1
8 INSERM UNITE 35 14981 0% 100% 1
9 INTERNAL MED 3200 HENRY AVE 14981 0% 100% 1
10 MACROPHAGE BIOL 1 GUTHRIE SQ 14981 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 7425 9% 0% 185
2 FEBS LETTERS 4406 5% 0% 111
3 CANCER RESEARCH 2403 4% 0% 81
4 ADVANCES IN SECOND MESSENGER AND PHOSPHOPROTEIN RESEARCH 2264 0% 3% 6
5 SECOND MESSENGERS AND PHOSPHOPROTEINS 2241 0% 5% 3
6 ADVANCES IN CYCLIC NUCLEOTIDE AND PROTEIN PHOSPHORYLATION RESEARCH 1755 0% 3% 4
7 JOURNAL OF BIOLOGICAL CHEMISTRY 1589 7% 0% 134
8 BIOCHIMICA ET BIOPHYSICA ACTA 1437 3% 0% 54
9 CELLULAR SIGNALLING 1341 1% 0% 20
10 CARCINOGENESIS 1189 2% 0% 31

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PROTEIN KINASE C 101065 12% 3% 251 Search PROTEIN+KINASE+C Search PROTEIN+KINASE+C
2 PHORBOL ESTER 31737 3% 3% 61 Search PHORBOL+ESTER Search PHORBOL+ESTER
3 COW MAMMARY GLAND 29962 0% 100% 2 Search COW+MAMMARY+GLAND Search COW+MAMMARY+GLAND
4 GAMMA SUBSPECIES 29962 0% 100% 2 Search GAMMA+SUBSPECIES Search GAMMA+SUBSPECIES
5 PHORBOL ESTER RECEPTOR 22469 0% 50% 3 Search PHORBOL+ESTER+RECEPTOR Search PHORBOL+ESTER+RECEPTOR
6 PROTEIN KINASE C ISOZYMES 18653 0% 14% 9 Search PROTEIN+KINASE+C+ISOZYMES Search PROTEIN+KINASE+C+ISOZYMES
7 1 5 ISOQUINOLINYLSULPHONYL 2 METHYLPIPERAZINEH7 14981 0% 100% 1 Search 1+5+ISOQUINOLINYLSULPHONYL+2+METHYLPIPERAZINEH7 Search 1+5+ISOQUINOLINYLSULPHONYL+2+METHYLPIPERAZINEH7
8 1 OMEGA F 18FLUOROACYL 2 ACYLGLYCEROL 14981 0% 100% 1 Search 1+OMEGA+F+18FLUOROACYL+2+ACYLGLYCEROL Search 1+OMEGA+F+18FLUOROACYL+2+ACYLGLYCEROL
9 12 0 TETRA DECANOYL PHORBOL 13 ACETATE 14981 0% 100% 1 Search 12+0+TETRA+DECANOYL+PHORBOL+13+ACETATE Search 12+0+TETRA+DECANOYL+PHORBOL+13+ACETATE
10 17K MR PROTEIN 14981 0% 100% 1 Search 17K+MR+PROTEIN Search 17K+MR+PROTEIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 NISHIZUKA, Y , (1988) THE MOLECULAR HETEROGENEITY OF PROTEIN KINASE-C AND ITS IMPLICATIONS FOR CELLULAR-REGULATION.NATURE. VOL. 334. ISSUE 6184. P. 661-665 42 75% 4284
2 KIKKAWA, U , KISHIMOTO, A , NISHIZUKA, Y , (1989) THE PROTEIN KINASE-C FAMILY - HETEROGENEITY AND ITS IMPLICATIONS.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 58. ISSUE . P. 31-44 77 77% 744
3 SANDO, JJ , MAURER, MC , BOLEN, EJ , GRISHAM, CM , (1992) ROLE OF COFACTORS IN PROTEIN-KINASE-C ACTIVATION.CELLULAR SIGNALLING. VOL. 4. ISSUE 6. P. 595-609 96 63% 47
4 NELSESTUEN, GL , BAZZI, MD , (1991) ACTIVATION AND REGULATION OF PROTEIN-KINASE-C ENZYMES.JOURNAL OF BIOENERGETICS AND BIOMEMBRANES. VOL. 23. ISSUE 1. P. 43-61 74 72% 103
5 NISHIZUKA, Y , (1986) STUDIES AND PERSPECTIVES OF PROTEIN-KINASE-C.SCIENCE. VOL. 233. ISSUE 4761. P. 305-312 67 25% 5282
6 ASHENDEL, CL , (1985) THE PHORBOL ESTER RECEPTOR - A PHOSPHOLIPID-REGULATED PROTEIN-KINASE.BIOCHIMICA ET BIOPHYSICA ACTA. VOL. 822. ISSUE 2. P. 219-242 88 50% 549
7 ZIDOVETZKI, R , LESTER, DS , (1992) THE MECHANISM OF ACTIVATION OF PROTEIN-KINASE-C - A BIOPHYSICAL PERSPECTIVE.BIOCHIMICA ET BIOPHYSICA ACTA. VOL. 1134. ISSUE 3. P. 261-272 65 63% 88
8 BELL, RM , BURNS, DJ , (1991) LIPID ACTIVATION OF PROTEIN-KINASE-C.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 266. ISSUE 8. P. 4661-4664 42 62% 573
9 NISHIZUKA, Y , (1984) THE ROLE OF PROTEIN KINASE-C IN CELL-SURFACE SIGNAL TRANSDUCTION AND TUMOR PROMOTION.NATURE. VOL. 308. ISSUE 5961. P. 693-698 24 49% 7885
10 SHEARMAN, MS , SEKIGUCHI, K , NISHIZUKA, Y , (1989) MODULATION OF ION CHANNEL ACTIVITY - A KEY FUNCTION OF THE PROTEIN KINASE-C ENZYME FAMILY.PHARMACOLOGICAL REVIEWS. VOL. 41. ISSUE 2. P. 211-237 88 36% 323

Classes with closest relation at Level 1


Rank Class id link
1 1767 PROTEIN KINASE C//PKC DELTA//CELLULAR CARCINOGENESIS TUMOR PROMOT
2 32412 1 2 OLEOYLACETYLGLYCEROL OAG//BETA IPKC//BIBLICAL TRAGEDY
3 21004 TELEOCIDIN//TUMOR PROMOTER//PENDOLMYCIN
4 19607 MARCKS//MYRISTOYLATED ALANINE RICH C KINASE SUBSTRATE//MARCKS RELATED PROTEIN
5 7370 CARCINOGENESIS//HYDROPEROXIDE PRODUCTION//PROTECT MAN ECOSYST
6 17826 BRYOSTATIN//BRYOSTATIN 1//APLYSIATOXIN
7 11603 BRAIN CORTICAL SLICES//PHOSPHOINOSITIDE BREAKDOWN//CMP PHOSPHATIDATE
8 34592 BALANOL//3 AMINO 4 HYDROXYHEXAHYDROAZEPINE//OPHIOCORDIN
9 5623 HUMAN PLATELETS//SIGNAL TRANSDUCTION DEFECTS//CNRS UNITE 646
10 14767 CELL TRANSFORMATION ASSAY//BHAS 42 CELLS//BALB C 3T3 CELL LINE

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