Class information for:
Level 1: IROFULVEN//ILLUDINS//MGI 114

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
29495 185 38.4 73%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
17 4 REPRODUCTIVE BIOLOGY//OBSTETRICS & GYNECOLOGY//VETERINARY SCIENCES 563730
256 3       VETERINARY SCIENCES//DOG//JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION 44961
3360 2             PTERIDIUM AQUILINUM//BRACKEN//EQUINE SARCOID 1696
29495 1                   IROFULVEN//ILLUDINS//MGI 114 185

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IROFULVEN authKW 4694934 17% 89% 32
2 ILLUDINS authKW 3760185 15% 84% 27
3 MGI 114 authKW 2979268 10% 95% 19
4 HMAF authKW 2156737 8% 93% 14
5 6 HYDROXYMETHYLACYLFULVENE authKW 1320452 4% 100% 8
6 ACYLFULVENE authKW 1320452 4% 100% 8
7 ALKENAL ONE OXIDOREDUCTASE authKW 330113 1% 100% 2
8 DIFFERENTIAL APOPTOSIS authKW 330113 1% 100% 2
9 HYDROXYMETHYLACYLFULVENE authKW 330113 1% 100% 2
10 ILLUDIN M authKW 330113 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 1113 41% 0% 75
2 Pharmacology & Pharmacy 495 31% 0% 58
3 Chemistry, Medicinal 451 15% 0% 28
4 Chemistry, Organic 147 14% 0% 26
5 Toxicology 132 9% 0% 16
6 Mycology 24 2% 0% 3
7 Plant Sciences 14 5% 0% 10
8 Chemistry, Multidisciplinary 13 9% 0% 16
9 Biochemistry & Molecular Biology 9 11% 0% 20
10 Hematology 3 2% 0% 4

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PATHOL 8320 330113 1% 100% 2
2 CORE IL PROTE STRUCT BIOL 165057 1% 100% 1
3 DR JACQUES POUYSSEGUR 165057 1% 100% 1
4 GENITOURY ONCOL SERV 165057 1% 100% 1
5 MAY BABB RANDOLPH CANC 165057 1% 100% 1
6 NORDAN COLON DRUG DEV 165057 1% 100% 1
7 SIGNAL TRANSDUCT CELLULAR FUNCT DIABET DI 165057 1% 100% 1
8 UNITE 524 INSERM 165057 1% 100% 1
9 GRP BIOL PHARMACOGENET HUMAN TUMORS 132043 1% 40% 2
10 CANC CELL BIOL BRANCH 110035 1% 33% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INVESTIGATIONAL NEW DRUGS 7819 6% 0% 11
2 CANCER CHEMOTHERAPY AND PHARMACOLOGY 2713 6% 0% 11
3 CHEMICAL RESEARCH IN TOXICOLOGY 1135 3% 0% 6
4 METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY 1008 2% 0% 4
5 ANTI-CANCER DRUGS 803 2% 0% 4
6 XENOBIOTICA 676 2% 0% 4
7 JOURNAL OF NATURAL PRODUCTS 487 3% 0% 6
8 BIOCHEMICAL PHARMACOLOGY 428 4% 0% 7
9 CLINICAL CANCER RESEARCH 392 3% 0% 6
10 AUSTRALIAN JOURNAL OF CROP SCIENCE 370 1% 0% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 IROFULVEN 4694934 17% 89% 32 Search IROFULVEN Search IROFULVEN
2 ILLUDINS 3760185 15% 84% 27 Search ILLUDINS Search ILLUDINS
3 MGI 114 2979268 10% 95% 19 Search MGI+114 Search MGI+114
4 HMAF 2156737 8% 93% 14 Search HMAF Search HMAF
5 6 HYDROXYMETHYLACYLFULVENE 1320452 4% 100% 8 Search 6+HYDROXYMETHYLACYLFULVENE Search 6+HYDROXYMETHYLACYLFULVENE
6 ACYLFULVENE 1320452 4% 100% 8 Search ACYLFULVENE Search ACYLFULVENE
7 ALKENAL ONE OXIDOREDUCTASE 330113 1% 100% 2 Search ALKENAL+ONE+OXIDOREDUCTASE Search ALKENAL+ONE+OXIDOREDUCTASE
8 DIFFERENTIAL APOPTOSIS 330113 1% 100% 2 Search DIFFERENTIAL+APOPTOSIS Search DIFFERENTIAL+APOPTOSIS
9 HYDROXYMETHYLACYLFULVENE 330113 1% 100% 2 Search HYDROXYMETHYLACYLFULVENE Search HYDROXYMETHYLACYLFULVENE
10 ILLUDIN M 330113 1% 100% 2 Search ILLUDIN+M Search ILLUDIN+M

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 SCHOBERT, R , KNAUER, S , SEIBT, S , BIERSACK, B , (2011) ANTICANCER ACTIVE ILLUDINS: RECENT DEVELOPMENTS OF A POTENT ALKYLATING COMPOUND CLASS.CURRENT MEDICINAL CHEMISTRY. VOL. 18. ISSUE 6. P. 790 -807 61 80% 20
2 TANASOVA, M , STURLA, SJ , (2012) CHEMISTRY AND BIOLOGY OF ACYLFULVENES: SESQUITERPENE-DERIVED ANTITUMOR AGENTS.CHEMICAL REVIEWS. VOL. 112. ISSUE 6. P. 3578-3610 89 40% 14
3 KELNER, MJ , MCMORRIS, TC , ROJAS, RJ , ESTES, LA , SUTHIPINIJTHAM, P , (2008) SYNERGY OF IROFULVEN IN COMBINATION WITH VARIOUS ANTI-METABOLITES, ENZYME INHIBITORS, AND MISCELLANEOUS AGENTS IN MV522 LUNG CARCINOMA CELLS: MARKED INTERACTION WITH GEMCITABINE AND 5-FLUOROURACIL.INVESTIGATIONAL NEW DRUGS. VOL. 26. ISSUE 5. P. 407 -415 40 71% 5
4 BOMGAARS, LR , MEGASON, GC , PULLEN, J , LANGEVIN, AM , WEITMAN, SD , HERSHON, L , KUHN, JG , BERNSTEIN, M , BLANEY, SM , (2006) PHASE I TRIAL OF IROFULVEN (MGI 114) IN PEDIATRIC PATIENTS WITH SOLID TUMORS.PEDIATRIC BLOOD & CANCER. VOL. 47. ISSUE 2. P. 163-168 27 100% 2
5 KELNER, MJ , MCMORRIS, TC , ROJAS, RJ , ESTES, LA , SUTHIPINIJTHAM, P , (2008) SYNERGY OF IROFULVEN IN COMBINATION WITH OTHER DNA DAMAGING AGENTS: SYNERGISTIC INTERACTION WITH ALTRETAMINE, ALKYLATING, AND PLATINUM-DERIVED AGENTS IN THE MV522 LUNG TUMOR MODEL.CANCER CHEMOTHERAPY AND PHARMACOLOGY. VOL. 63. ISSUE 1. P. 19 -26 27 75% 8
6 MCMORRIS, TC , YU, J , LIRA, R , DAWE, R , MACDONALD, JR , WATERS, SJ , ESTES, LA , KELNER, MJ , (2001) STRUCTURE-ACTIVITY STUDIES OF ANTITUMOR AGENT IROFULVEN (HYDROXYMETHYLACYLFULVENE) AND ANALOGUES.JOURNAL OF ORGANIC CHEMISTRY. VOL. 66. ISSUE 18. P. 6158-6163 24 96% 18
7 PIETSCH, KE , VAN MIDWOUD, PM , VILLALTA, PW , STURLA, SJ , (2013) QUANTIFICATION OF ACYLFULVENE- AND ILLUDIN S-DNA ADDUCTS IN CELLS WITH VARIABLE BIOACTIVATION CAPACITIES.CHEMICAL RESEARCH IN TOXICOLOGY. VOL. 26. ISSUE 1. P. 146-155 21 75% 3
8 GLATT, H , PIETSCH, KE , STURLA, SJ , MEINL, W , (2014) SULFOTRANSFERASE-INDEPENDENT GENOTOXICITY OF ILLUDIN S AND ITS ACYLFULVENE DERIVATIVES IN BACTERIAL AND MAMMALIAN CELLS.ARCHIVES OF TOXICOLOGY. VOL. 88. ISSUE 1. P. 161-169 24 65% 0
9 KELNER, MJ , MCMORRIS, TC , ROJAS, RJ , TRANI, NA , VELASCO, TR , ESTES, LA , SUTHIPINIJTHAM, P , (2002) ENHANCED ANTITUMOR ACTIVITY OF IROFULVEN IN COMBINATION WITH ANTIMITOTIC AGENTS.INVESTIGATIONAL NEW DRUGS. VOL. 20. ISSUE 3. P. 271-279 21 84% 13
10 WOO, MH , PETERSON, JK , BILLUPS, C , LIANG, H , BJORNSTI, MA , HOUGHTON, PJ , (2005) ENHANCED ANTITUMOR ACTIVITY OF IROFULVEN IN COMBINATION WITH IRINOTECAN IN PEDIATRIC SOLID TUMOR XENOGRAFT MODELS.CANCER CHEMOTHERAPY AND PHARMACOLOGY. VOL. 55. ISSUE 5. P. 411 -419 21 72% 17

Classes with closest relation at Level 1


Rank Class id link
1 13615 PROTOILLUDANE//LACTARIUS VELLEREUS//BOREOSTEREUM VIBRANS
2 34043 LOXOPROFEN//CS 670//PELUBIPROFEN
3 20170 BRACKEN//PTAQUILOSIDE//PTERIDIUM AQUILINUM
4 34019 ANGINEX//ENDOTOXIN NEUTRALIZING//TUMOR ANGIOGENESIS
5 12060 METHYLENECYCLOPROPANE//BICYCLOPROPYLIDENE//VINYLIDENECYCLOPROPANES
6 17114 DUOCARMYCIN//CC 1065//ADOZELESIN
7 25991 15 HYDROXYPROSTAGLANDIN DEHYDROGENASE//15 PGDH//15 HYDROXYPROSTAGLANDIN DEHYDROGENASE 15 PGDH
8 28135 CYCLOALKYLIDENEPYRAZOLINONES//IMINO PIPERIDINE//SPIROHETEROCYCLES
9 36486 SORDARIN//SORDARICIN//ZOFIMARIN
10 25189 GRIFOLIN//CURTISIAN//THELEPHORA AURANTIOTINCTA

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