Class information for:
Level 1: CHIMERIC ANTIGEN RECEPTOR//ADOPTIVE CELL THERAPY//SURG BRANCH

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2862 2128 53.3 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
10 3       IMMUNOLOGY//JOURNAL OF IMMUNOLOGY//IMMUNOL 134299
140 2             IMMUNOTHERAPY//DENDRITIC CELLS//CANCER IMMUNOLOGY IMMUNOTHERAPY 23462
2862 1                   CHIMERIC ANTIGEN RECEPTOR//ADOPTIVE CELL THERAPY//SURG BRANCH 2128

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHIMERIC ANTIGEN RECEPTOR authKW 2194625 10% 71% 216
2 ADOPTIVE CELL THERAPY authKW 486916 3% 46% 73
3 SURG BRANCH address 414993 8% 17% 174
4 ADOPTIVE T CELL THERAPY authKW 364486 3% 43% 59
5 ADOPTIVE IMMUNOTHERAPY authKW 306210 5% 18% 117
6 CELL GENE THER Y address 274644 8% 12% 166
7 ADOPTIVE CELL TRANSFER authKW 197409 2% 40% 34
8 CELLULAR IMMUNOTHER IES address 188467 1% 77% 17
9 CHIMERIC IMMUNE RECEPTOR authKW 173193 1% 93% 13
10 CHIMERIC ANTIGEN RECEPTOR T CELLS authKW 161646 1% 87% 13

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Medicine, Research & Experimental 14953 32% 0% 672
2 Immunology 9787 33% 0% 705
3 Oncology 8692 34% 0% 720
4 Hematology 7088 18% 0% 385
5 Biotechnology & Applied Microbiology 3959 19% 0% 409
6 Genetics & Heredity 2122 14% 0% 303
7 Cell & Tissue Engineering 1667 3% 0% 57
8 Cell Biology 313 8% 0% 175
9 Transplantation 75 2% 0% 35
10 Multidisciplinary Sciences 49 1% 0% 23

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SURG BRANCH 414993 8% 17% 174
2 CELL GENE THER Y 274644 8% 12% 166
3 CELLULAR IMMUNOTHER IES 188467 1% 77% 17
4 CLIN EXPT IMMUNOTHER Y GRP 157823 1% 100% 11
5 EXPT TUMOR IMMUNOL 140598 1% 70% 14
6 THER EUT IMMUNOMOL 89817 1% 52% 12
7 TUMORGENET 89665 0% 63% 10
8 EXPT HEMATOL UNIT 75366 1% 31% 17
9 RIC MATILDE TETTAMANTI 73786 0% 86% 6
10 UNIT 907 63907 0% 64% 7

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF IMMUNOTHERAPY 63000 4% 5% 86
2 CANCER IMMUNOLOGY RESEARCH 28703 1% 7% 30
3 HUMAN GENE THERAPY 26760 4% 2% 79
4 ONCOIMMUNOLOGY 22776 2% 4% 39
5 MOLECULAR THERAPY 22677 4% 2% 75
6 IMMUNOTHERAPY 21638 2% 5% 33
7 CYTOTHERAPY 17693 2% 3% 45
8 GENE THERAPY 14928 3% 2% 64
9 MOLECULAR THERAPY-ONCOLYTICS 14561 0% 13% 8
10 CANCER IMMUNOLOGY IMMUNOTHERAPY 13875 3% 2% 65

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CHIMERIC ANTIGEN RECEPTOR 2194625 10% 71% 216 Search CHIMERIC+ANTIGEN+RECEPTOR Search CHIMERIC+ANTIGEN+RECEPTOR
2 ADOPTIVE CELL THERAPY 486916 3% 46% 73 Search ADOPTIVE+CELL+THERAPY Search ADOPTIVE+CELL+THERAPY
3 ADOPTIVE T CELL THERAPY 364486 3% 43% 59 Search ADOPTIVE+T+CELL+THERAPY Search ADOPTIVE+T+CELL+THERAPY
4 ADOPTIVE IMMUNOTHERAPY 306210 5% 18% 117 Search ADOPTIVE+IMMUNOTHERAPY Search ADOPTIVE+IMMUNOTHERAPY
5 ADOPTIVE CELL TRANSFER 197409 2% 40% 34 Search ADOPTIVE+CELL+TRANSFER Search ADOPTIVE+CELL+TRANSFER
6 CHIMERIC IMMUNE RECEPTOR 173193 1% 93% 13 Search CHIMERIC+IMMUNE+RECEPTOR Search CHIMERIC+IMMUNE+RECEPTOR
7 CHIMERIC ANTIGEN RECEPTOR T CELLS 161646 1% 87% 13 Search CHIMERIC+ANTIGEN+RECEPTOR+T+CELLS Search CHIMERIC+ANTIGEN+RECEPTOR+T+CELLS
8 TCR GENE TRANSFER 161646 1% 87% 13 Search TCR+GENE+TRANSFER Search TCR+GENE+TRANSFER
9 CHIMERIC T CELL RECEPTOR 147571 1% 86% 12 Search CHIMERIC+T+CELL+RECEPTOR Search CHIMERIC+T+CELL+RECEPTOR
10 TCR GENE THERAPY 133539 1% 85% 11 Search TCR+GENE+THERAPY Search TCR+GENE+THERAPY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KERSHAW, MH , WESTWOOD, JA , DARCY, PK , (2013) GENE-ENGINEERED T CELLS FOR CANCER THERAPY.NATURE REVIEWS CANCER. VOL. 13. ISSUE 8. P. 525-541 152 85% 107
2 DAI, HR , WANG, Y , LU, XC , HAN, WD , (2016) CHIMERIC ANTIGEN RECEPTORS MODIFIED T-CELLS FOR CANCER THERAPY.JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. VOL. 108. ISSUE 7. P. - 127 82% 9
3 ANURATHAPAN, U , LEEN, AM , BRENNER, MK , VERA, JF , (2014) ENGINEERED T CELLS FOR CANCER TREATMENT.CYTOTHERAPY. VOL. 16. ISSUE 6. P. 713-733 177 83% 11
4 GILL, S , JUNE, CH , (2015) GOING VIRAL: CHIMERIC ANTIGEN RECEPTOR T-CELL THERAPY FOR HEMATOLOGICAL MALIGNANCIES.IMMUNOLOGICAL REVIEWS. VOL. 263. ISSUE 1. P. 68 -89 112 69% 74
5 GROSS, G , ESHHAR, Z , (2016) THERAPEUTIC POTENTIAL OF T CELL CHIMERIC ANTIGEN RECEPTORS (CARS) IN CANCER TREATMENT: COUNTERACTING OFF-TUMOR TOXICITIES FOR SAFE CAR T CELL THERAPY.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 56. VOL. 56. ISSUE . P. 59 -+ 108 82% 10
6 DOTTI, G , GOTTSCHALK, S , SAVOLDO, B , BRENNER, MK , (2014) DESIGN AND DEVELOPMENT OF THERAPIES USING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING T CELLS.IMMUNOLOGICAL REVIEWS. VOL. 257. ISSUE 1. P. 107 -126 138 74% 57
7 RUELLA, M , KALOS, M , (2014) ADOPTIVE IMMUNOTHERAPY FOR CANCER.IMMUNOLOGICAL REVIEWS. VOL. 257. ISSUE 1. P. 14 -38 198 60% 24
8 ROSENBERG, SA , RESTIFO, NP , (2015) ADOPTIVE CELL TRANSFER AS PERSONALIZED IMMUNOTHERAPY FOR HUMAN CANCER.SCIENCE. VOL. 348. ISSUE 6230. P. 62 -68 60 67% 203
9 ALMASBAK, H , AARVAK, T , VEMURI, MC , (2016) CAR T CELL THERAPY: A GAME CHANGER IN CANCER TREATMENT.JOURNAL OF IMMUNOLOGY RESEARCH. VOL. . ISSUE . P. - 100 90% 4
10 SPEAR, TT , NAGATO, K , NISHIMURA, MI , (2016) STRATEGIES TO GENETICALLY ENGINEER T CELLS FOR CANCER IMMUNOTHERAPY.CANCER IMMUNOLOGY IMMUNOTHERAPY. VOL. 65. ISSUE 6. P. 631 -649 145 80% 0

Classes with closest relation at Level 1


Rank Class id link
1 33425 ARTIFICIAL ANTIGEN PRESENTING CELLS//ANTIGEN SPECIFIC CD8T CELLS//HLA A2 IG
2 24733 TUMOR IMMUN TOLERANCE SECT//SV40 T ANTIGEN TRANSGENIC MICE//CCDC134
3 20004 CYTOKINE INDUCED KILLER CELLS//CIK CELLS//CIK
4 13833 PROT CRYSTALLOG UNIT//T CELL RECEPTOR//PEPTIDE MHC
5 1375 CANCER TESTIS ANTIGEN//NY ESO 1//MAGE
6 30077 2A PEPTIDE//FMDV 2A//2A
7 2246 LENTIVIRAL VECTOR//EXPT HEMATOL//RETROVIRAL VECTOR
8 15248 MINOR HISTOCOMPATIBILITY ANTIGENS//HA 1//HY ANTIGENS
9 721 PD L1//PD 1//IPILIMUMAB
10 15817 PRAME//LEUKEMIA ASSOCIATED ANTIGENS//PREFERENTIALLY EXPRESSED ANTIGEN OF MELANOMA

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