Class information for:
Level 1: ALPHA AMINOADIPATE PATHWAY//HOMOCITRATE SYNTHASE//ALPHA AMINOADIPATE REDUCTASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
28290 210 30.6 57%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
278 3       CORYNEBACTERIUM GLUTAMICUM//ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY//BIOCHEMISTRY & MOLECULAR BIOLOGY 43163
1967 2             GLUTAMATE DEHYDROGENASE//3 ISOPROPYLMALATE DEHYDROGENASE//ISOCITRATE DEHYDROGENASE 5642
28290 1                   ALPHA AMINOADIPATE PATHWAY//HOMOCITRATE SYNTHASE//ALPHA AMINOADIPATE REDUCTASE 210

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ALPHA AMINOADIPATE PATHWAY authKW 1118508 5% 77% 10
2 HOMOCITRATE SYNTHASE authKW 1038614 5% 71% 10
3 ALPHA AMINOADIPATE REDUCTASE authKW 775497 4% 67% 8
4 LYSINE BIOSYNTHESIS authKW 661043 10% 22% 21
5 SACCHAROPINE REDUCTASE authKW 465300 2% 80% 4
6 LYS2 authKW 403903 2% 56% 5
7 SACCHAROPINE DEHYDROGENASE authKW 357913 4% 31% 8
8 ALPHA AMINOADIPATE REDUCTASE AAR authKW 290813 1% 100% 2
9 HOMOISOCITRATE authKW 290813 1% 100% 2
10 CITRAMALATE SYNTHASE authKW 261730 1% 60% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 1111 60% 0% 125
2 Microbiology 845 27% 0% 57
3 Mycology 471 6% 0% 13
4 Biophysics 195 12% 0% 25
5 Genetics & Heredity 139 12% 0% 25
6 Biotechnology & Applied Microbiology 88 10% 0% 21
7 Evolutionary Biology 29 3% 0% 6
8 Biochemical Research Methods 28 5% 0% 10
9 Mathematical & Computational Biology 16 2% 0% 4
10 Agronomy 9 2% 0% 5

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MICROBIAL MOL PHYSIOL 218107 1% 50% 3
2 BIOTECHNOL AGRO INDINRACNRS 145407 0% 100% 1
3 FISICOQUIM INGN PROTEINAS 145407 0% 100% 1
4 SHANGHAI INT TRAVEL HEALTHCARE 145407 0% 100% 1
5 ECOL NAT SYST 116319 2% 20% 4
6 MICROBIAL TECHNOL PROC DEV 72702 0% 50% 1
7 BIOCHEM ANALBUNKYO KU 72700 1% 25% 2
8 GENET MOL CELL 48468 0% 33% 1
9 NAT SYST ECOL 36350 0% 25% 1
10 STRUCTUROME PROJECT 24233 0% 17% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 YEAST 5118 5% 0% 10
2 JOURNAL OF BASIC MICROBIOLOGY 2222 3% 0% 6
3 CURRENT GENETICS 1929 3% 0% 7
4 CRC CRITICAL REVIEWS IN MICROBIOLOGY 1438 0% 1% 1
5 BIOCHEMISTRY 1303 10% 0% 22
6 JOURNAL OF BACTERIOLOGY 1106 8% 0% 16
7 MSPHERE 994 0% 1% 1
8 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 537 4% 0% 8
9 AGRICULTURAL AND BIOLOGICAL CHEMISTRY 514 2% 0% 5
10 FEMS MICROBIOLOGY LETTERS 439 3% 0% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ALPHA AMINOADIPATE PATHWAY 1118508 5% 77% 10 Search ALPHA+AMINOADIPATE+PATHWAY Search ALPHA+AMINOADIPATE+PATHWAY
2 HOMOCITRATE SYNTHASE 1038614 5% 71% 10 Search HOMOCITRATE+SYNTHASE Search HOMOCITRATE+SYNTHASE
3 ALPHA AMINOADIPATE REDUCTASE 775497 4% 67% 8 Search ALPHA+AMINOADIPATE+REDUCTASE Search ALPHA+AMINOADIPATE+REDUCTASE
4 LYSINE BIOSYNTHESIS 661043 10% 22% 21 Search LYSINE+BIOSYNTHESIS Search LYSINE+BIOSYNTHESIS
5 SACCHAROPINE REDUCTASE 465300 2% 80% 4 Search SACCHAROPINE+REDUCTASE Search SACCHAROPINE+REDUCTASE
6 LYS2 403903 2% 56% 5 Search LYS2 Search LYS2
7 SACCHAROPINE DEHYDROGENASE 357913 4% 31% 8 Search SACCHAROPINE+DEHYDROGENASE Search SACCHAROPINE+DEHYDROGENASE
8 ALPHA AMINOADIPATE REDUCTASE AAR 290813 1% 100% 2 Search ALPHA+AMINOADIPATE+REDUCTASE+AAR Search ALPHA+AMINOADIPATE+REDUCTASE+AAR
9 HOMOISOCITRATE 290813 1% 100% 2 Search HOMOISOCITRATE Search HOMOISOCITRATE
10 CITRAMALATE SYNTHASE 261730 1% 60% 3 Search CITRAMALATE+SYNTHASE Search CITRAMALATE+SYNTHASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 XU, HY , ANDI, B , QIAN, JH , WEST, AH , COOK, PF , (2006) THE ALPHA-AMINOADIPATE PATHWAY FOR LYSINE BIOSYNTHESIS IN FUNGI.CELL BIOCHEMISTRY AND BIOPHYSICS. VOL. 46. ISSUE 1. P. 43-64 41 48% 70
2 GABRIEL, I , MILEWSKI, S , (2016) CHARACTERIZATION OF RECOMBINANT HOMOCITRATE SYNTHASE FROM CANDIDA ALBICANS.PROTEIN EXPRESSION AND PURIFICATION. VOL. 125. ISSUE . P. 7 -18 21 81% 0
3 ZABRISKIE, TM , JACKSON, MD , (2000) LYSINE BIOSYNTHESIS AND METABOLISM IN FUNGI.NATURAL PRODUCT REPORTS. VOL. 17. ISSUE 1. P. 85 -97 45 45% 85
4 OKADA, T , TOMITA, T , WULANDARI, AP , KUZUYAMA, T , NISHIYAMA, M , (2010) MECHANISM OF SUBSTRATE RECOGNITION AND INSIGHT INTO FEEDBACK INHIBITION OF HOMOCITRATE SYNTHASE FROM THERMUS THERMOPHILUS.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 285. ISSUE 6. P. 4195-4205 22 59% 10
5 BULFER, SL , SCOTT, EM , PILLUS, L , TRIEVEL, RC , (2010) STRUCTURAL BASIS FOR L-LYSINE FEEDBACK INHIBITION OF HOMOCITRATE SYNTHASE.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 285. ISSUE 14. P. 10446 -10453 18 62% 10
6 HUNTER, MFC , PARKER, EJ , (2014) MODIFYING THE DETERMINANTS OF ALPHA-KETOACID SUBSTRATE SELECTIVITY IN MYCOBACTERIUM TUBERCULOSIS ALPHA-ISOPROPYLMALATE SYNTHASE.FEBS LETTERS. VOL. 588. ISSUE 9. P. 1603-1607 13 72% 1
7 EKANAYAKE, DK , WEST, AH , COOK, PF , (2011) CONTRIBUTION OF K99 AND D319 TO SUBSTRATE BINDING AND CATALYSIS IN THE SACCHAROPINE DEHYDROGENASE REACTION.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 514. ISSUE 1-2. P. 8-15 11 92% 1
8 KUMAR, VP , WEST, AH , COOK, PF , (2012) SUPPORTING ROLE OF LYSINE 13 AND GLUTAMATE 16 IN THE ACID-BASE MECHANISM OF SACCHAROPINE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 522. ISSUE 1. P. 57-61 10 91% 2
9 EKANAYAKE, DK , ANDI, B , BOBYK, KD , WEST, AH , COOK, PF , (2010) GLUTAMATES 78 AND 122 IN THE ACTIVE SITE OF SACCHAROPINE DEHYDROGENASE CONTRIBUTE TO REACTANT BINDING AND MODULATE THE BASICITY OF THE ACID-BASE CATALYSTS.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 285. ISSUE 27. P. 20756-20768 11 85% 2
10 ZHANG, ZL , WU, J , LIN, W , WANG, J , YAN, H , ZHAO, W , MA, J , DING, JP , ZHANG, P , ZHAO, GP , (2014) SUBDOMAIN II OF ALPHA-ISOPROPYLMALATE SYNTHASE IS ESSENTIAL FOR ACTIVITY INFERRING A MECHANISM OF FEEDBACK INHIBITION.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 289. ISSUE 40. P. 27966 -27978 15 54% 1

Classes with closest relation at Level 1


Rank Class id link
1 24162 THERMUS//MEIOTHERMUS//THERMUS SPP
2 14942 3 ISOPROPYLMALATE DEHYDROGENASE//ISOCITRATE DEHYDROGENASE//ISOPROPYLMALATE DEHYDROGENASE
3 36009 ARXULA ADENINIVORANS//AUXOTROPHIC SELECTION MARKER//APHO1
4 6404 STREPTOMYCES CLAVULIGERUS//ACREMONIUM CHRYSOGENUM//CEPHALOSPORIUM ACREMONIUM
5 10704 DIHYDRODIPICOLINATE SYNTHASE//ASPARTATE KINASE//LYSINE BIOSYNTHESIS
6 18362 L AMINO ACID OXIDASE//L LYSINE ALPHA OXIDASE//LYSINE OXIDASE
7 20877 PHENYLALANINE DEHYDROGENASE//LEUCINE DEHYDROGENASE//VALINE DEHYDROGENASE
8 22069 ARGININE REPRESSOR//ARGININE REPRESSOR PROTEIN//ARGR
9 25090 2 METHYLCITRIC ACID CYCLE//PROPIONATE METABOLISM//2 METHYLCITRATE SYNTHASE
10 11310 GAL80//GAL4P//GAL4

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