Class information for:
Level 1: SERINE BIOSYNTHESIS//SERINE DEFICIENCY//3 PHOSPHOGLYCERATE DEHYDROGENASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
28022 215 32.0 72%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
278 3       CORYNEBACTERIUM GLUTAMICUM//ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY//BIOCHEMISTRY & MOLECULAR BIOLOGY 43163
1584 2             D AMINO ACID OXIDASE//D SERINE//SERINE RACEMASE 7221
28022 1                   SERINE BIOSYNTHESIS//SERINE DEFICIENCY//3 PHOSPHOGLYCERATE DEHYDROGENASE 215

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SERINE BIOSYNTHESIS authKW 718994 4% 56% 9
2 SERINE DEFICIENCY authKW 710125 2% 100% 5
3 3 PHOSPHOGLYCERATE DEHYDROGENASE authKW 535319 3% 54% 7
4 ASCT1 authKW 535319 3% 54% 7
5 PHOSPHOSERINE AMINOTRANSFERASE authKW 497081 3% 50% 7
6 PHOSPHORYLATED PATHWAY authKW 454479 2% 80% 4
7 ASPARAGINE SYNTHETASE DEFICIENCY authKW 426075 1% 100% 3
8 3 PGDH DEFICIENCY authKW 284050 1% 100% 2
9 3 PHOSPHOSERINE PHOSPHATASE authKW 284050 1% 100% 2
10 HOMOLOGOUS ALIGNMENT authKW 284050 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 813 51% 0% 110
2 Genetics & Heredity 308 17% 0% 36
3 Biophysics 142 10% 0% 22
4 Neurosciences 60 12% 0% 26
5 Pediatrics 38 6% 0% 12
6 Medicine, Research & Experimental 37 6% 0% 13
7 Clinical Neurology 34 7% 0% 15
8 Endocrinology & Metabolism 27 6% 0% 12
9 Cell Biology 20 7% 0% 15
10 Parasitiology 6 1% 0% 3

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 METAB ARCHITECTURE DESIGN 189365 1% 67% 2
2 BEHAB GENET 142025 0% 100% 1
3 BIOTECHNOL MED OURCES 142025 0% 100% 1
4 CLIN NEUROPHYISOL 142025 0% 100% 1
5 EXPT COMPLEX 142025 0% 100% 1
6 MED INAGE KU 142025 0% 100% 1
7 NEONATOL NEOPEDIAT INBORN ERROS METAB 142025 0% 100% 1
8 SERV BIOCHIM SPECIALISEEHOP NECKER ENFANTS MALAD 142025 0% 100% 1
9 SERV NEUROPEDIAT EXPLORAT FONCT 142025 0% 100% 1
10 WILD SILKMOTH LIAONING PROV 142025 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF INHERITED METABOLIC DISEASE 1528 3% 0% 7
2 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 1191 6% 0% 12
3 NEUROPEDIATRICS 1114 2% 0% 4
4 NEUROSCIENCE RESEARCH 627 2% 0% 4
5 ENTOMOLOGICAL RESEARCH 571 0% 0% 1
6 JOURNAL OF BIOLOGICAL CHEMISTRY 515 11% 0% 24
7 ARCHIVES OF HISTOLOGY AND CYTOLOGY 514 1% 0% 2
8 MOLECULAR GENETICS AND METABOLISM 405 1% 0% 3
9 CYTOGENETICS AND CELL GENETICS 373 1% 0% 3
10 AMINO ACIDS 353 1% 0% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SERINE BIOSYNTHESIS 718994 4% 56% 9 Search SERINE+BIOSYNTHESIS Search SERINE+BIOSYNTHESIS
2 SERINE DEFICIENCY 710125 2% 100% 5 Search SERINE+DEFICIENCY Search SERINE+DEFICIENCY
3 3 PHOSPHOGLYCERATE DEHYDROGENASE 535319 3% 54% 7 Search 3+PHOSPHOGLYCERATE+DEHYDROGENASE Search 3+PHOSPHOGLYCERATE+DEHYDROGENASE
4 ASCT1 535319 3% 54% 7 Search ASCT1 Search ASCT1
5 PHOSPHOSERINE AMINOTRANSFERASE 497081 3% 50% 7 Search PHOSPHOSERINE+AMINOTRANSFERASE Search PHOSPHOSERINE+AMINOTRANSFERASE
6 PHOSPHORYLATED PATHWAY 454479 2% 80% 4 Search PHOSPHORYLATED+PATHWAY Search PHOSPHORYLATED+PATHWAY
7 ASPARAGINE SYNTHETASE DEFICIENCY 426075 1% 100% 3 Search ASPARAGINE+SYNTHETASE+DEFICIENCY Search ASPARAGINE+SYNTHETASE+DEFICIENCY
8 3 PGDH DEFICIENCY 284050 1% 100% 2 Search 3+PGDH+DEFICIENCY Search 3+PGDH+DEFICIENCY
9 3 PHOSPHOSERINE PHOSPHATASE 284050 1% 100% 2 Search 3+PHOSPHOSERINE+PHOSPHATASE Search 3+PHOSPHOSERINE+PHOSPHATASE
10 HOMOLOGOUS ALIGNMENT 284050 1% 100% 2 Search HOMOLOGOUS+ALIGNMENT Search HOMOLOGOUS+ALIGNMENT

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 TABATABAIE, L , KLOMP, LW , BERGER, R , DE KONING, TJ , (2010) L-SERINE SYNTHESIS IN THE CENTRAL NERVOUS SYSTEM: A REVIEW ON SERINE DEFICIENCY DISORDERS.MOLECULAR GENETICS AND METABOLISM. VOL. 99. ISSUE 3. P. 256-262 46 56% 45
2 GRANT, GA , (2012) CONTRASTING CATALYTIC AND ALLOSTERIC MECHANISMS FOR PHOSPHOGLYCERATE DEHYDROGENASES.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 519. ISSUE 2. P. 175 -185 25 89% 9
3 EL-HATTAB, AW , (2016) SERINE BIOSYNTHESIS AND TRANSPORT DEFECTS.MOLECULAR GENETICS AND METABOLISM. VOL. 118. ISSUE 3. P. 153 -159 26 68% 2
4 BRASSIER, A , VALAYANNOPOULOS, V , BAHI-BUISSON, N , WIAME, E , HUBERT, L , BODDAERT, N , KAMINSKA, A , HABAROU, F , DESGUERRE, I , VAN SCHAFTINGEN, E , ET AL (2016) TWO NEW CASES OF SERINE DEFICIENCY DISORDERS TREATED WITH L-SERINE.EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY. VOL. 20. ISSUE 1. P. 53 -60 17 94% 1
5 TABATABAIE, L , DE KONING, TJ , GEBOERS, AJJM , VAN DEN BERG, IET , BERGER, R , KLOMP, LWJ , (2009) NOVEL MUTATIONS IN 3-PHOSPHOGLYCERATE DEHYDROGENASE (PHGDH) ARE DISTRIBUTED THROUGHOUT THE PROTEIN AND RESULT IN ALTERED ENZYME KINETICS.HUMAN MUTATION. VOL. 30. ISSUE 5. P. 749-756 24 77% 14
6 VAN DER CRABBEN, SN , VERHOEVEN-DUIF, NM , BRILSTRA, EH , VAN MALDERGEM, L , COSKUN, T , RUBIO-GOZALBO, E , BERGER, R , DE KONING, TJ , (2013) AN UPDATE ON SERINE DEFICIENCY DISORDERS.JOURNAL OF INHERITED METABOLIC DISEASE. VOL. 36. ISSUE 4. P. 613-619 16 89% 24
7 EL-HATTAB, AW , SHAHEEN, R , HERTECANT, J , GALADARI, HI , ALBAQAWI, BS , NABIL, A , ALKURAYA, FS , (2016) ON THE PHENOTYPIC SPECTRUM OF SERINE BIOSYNTHESIS DEFECTS.JOURNAL OF INHERITED METABOLIC DISEASE. VOL. 39. ISSUE 3. P. 373 -381 25 61% 0
8 KRAOUA, I , WIAME, E , KRAOUA, L , NASRALLAH, F , BENRHOUMA, H , ROUISSI, A , TURKI, I , CHAABOUNI, H , BRIAND, G , KAABACHI, N , ET AL (2013) 3-PHOSPHOGLYCERATE DEHYDROGENASE DEFICIENCY: DESCRIPTION OF TWO NEW CASES IN TUNISIA AND REVIEW OF THE LITERATURE.NEUROPEDIATRICS. VOL. 44. ISSUE 5. P. 281-285 14 100% 1
9 BURTON, RL , CHEN, SW , XU, XL , GRANT, GA , (2009) TRANSIENT KINETIC ANALYSIS OF THE INTERACTION OF L-SERINE WITH ESCHERICHIA COLI D-3-PHOSPHOGLYCERATE DEHYDROGENASE REVEALS THE MECHANISM OF V-TYPE REGULATION AND THE ORDER OF EFFECTOR BINDING.BIOCHEMISTRY. VOL. 48. ISSUE 51. P. 12242 -12251 19 79% 6
10 PIND, S , SLOMINSKI, E , MAUTHE, J , PEARLMAN, K , SWOBODA, KJ , WILKINS, JA , SAUDER, P , NATOWICZ, MR , (2002) V490M, A COMMON MUTATION IN 3-PHOSPHOGLYCERATE DEHYDROGENASE DEFICIENCY, CAUSES ENZYME DEFICIENCY BY DECREASING THE YIELD OF MATURE ENZYME.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 277. ISSUE 9. P. 7136-7143 25 57% 22

Classes with closest relation at Level 1


Rank Class id link
1 22226 THREONINE DEHYDROGENASE//L THREONINE DEHYDROGENASE//TDC OPERON
2 21684 NONKETOTIC HYPERGLYCINEMIA//GLYCINE CLEAVAGE SYSTEM//NKH
3 23719 UDP SUGAR HYDROLASE//SUGAR PHOSPHATASES//HAD SUPERFAMILY
4 5858 D AMINO ACID OXIDASE//D SERINE//SERINE RACEMASE
5 16904 PHOTORESPIRATION//GLYCOLATE OXIDASE//SERINE GLYOXYLATE AMINOTRANSFERASE
6 23151 SOCIAL SEPARATION STRESS//NEONATAL CHICK//REGULAT METAB BEHAV
7 13841 SERINE HYDROXYMETHYLTRANSFERASE//THREONINE ALDOLASE//SHMT
8 20804 PYRIDOXINE DEPENDENT EPILEPSY//PYRIDOXINE DEPENDENT SEIZURES//ALDH7A1
9 14399 MALATE DEHYDROGENASE//D LACTATE DEHYDROGENASE//D 2 HYDROXYACID DEHYDROGENASE
10 24624 APPARENT EQUILIBRIUM CONSTANTS//TRANSFORMED THERMODYNAMIC PROPERTIES//TRANSFORMED GIBBS ENERGY

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