Class information for:
Level 1: LIGHT CHAIN AMYLOIDOSIS//GLYCOSYLATED IMMUNOGLOBULIN LIGHT CHAIN//IMMUNOLOGICAL SIGNAL

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
25915 268 39.9 70%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
482 3       MULTIPLE MYELOMA//AMYLOIDOSIS//TRANSTHYRETIN 23544
967 2             AMYLOIDOSIS//TRANSTHYRETIN//AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS 10681
25915 1                   LIGHT CHAIN AMYLOIDOSIS//GLYCOSYLATED IMMUNOGLOBULIN LIGHT CHAIN//IMMUNOLOGICAL SIGNAL 268

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LIGHT CHAIN AMYLOIDOSIS authKW 894141 7% 41% 19
2 GLYCOSYLATED IMMUNOGLOBULIN LIGHT CHAIN authKW 455751 1% 100% 4
3 IMMUNOLOGICAL SIGNAL authKW 341813 1% 100% 3
4 PROT CRYSTALLOG PROGRAM address 341813 1% 100% 3
5 BENCE JONES PROTEIN authKW 275630 6% 16% 15
6 IMMUNOGLOBULIN LIGHT CHAIN authKW 272316 5% 17% 14
7 BIOINFORMAT TELEMED address 262703 5% 16% 14
8 HUMAN IMMUNOL CANC PROGRAM address 260409 4% 19% 12
9 BIOQUIM ONANCIA MAGNET NUCL address 256358 1% 75% 3
10 ANTIBODY AMYLOID authKW 227875 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 2031 70% 0% 188
2 Biophysics 607 18% 0% 48
3 Biochemical Research Methods 145 9% 0% 23
4 Immunology 134 12% 0% 33
5 Medicine, Research & Experimental 88 8% 0% 21
6 Medicine, General & Internal 32 7% 0% 18
7 Architecture 13 0% 0% 1
8 Literary Reviews 11 0% 0% 1
9 Crystallography 9 2% 0% 6
10 Pathology 8 2% 0% 6

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROT CRYSTALLOG PROGRAM 341813 1% 100% 3
2 BIOINFORMAT TELEMED 262703 5% 16% 14
3 HUMAN IMMUNOL CANC PROGRAM 260409 4% 19% 12
4 BIOQUIM ONANCIA MAGNET NUCL 256358 1% 75% 3
5 GERRY AMYLOID 227875 1% 100% 2
6 AMYLOID TREATMENT MED 113938 0% 100% 1
7 BIOL CHEMDOE 113938 0% 100% 1
8 BIOTECHNOL OLSO 113938 0% 100% 1
9 CHAIR METROL ELECT AGH 113938 0% 100% 1
10 CHEM BIOCHEMDOE 113938 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS 41967 6% 2% 17
2 CELL SURFACE REVIEWS 8137 0% 7% 1
3 VIA 7119 0% 6% 1
4 BIOLOGICAL CHEMISTRY HOPPE-SEYLER 3654 3% 0% 7
5 FOLIA HISTOCHEMICA ET CYTOBIOLOGICA 1606 2% 0% 5
6 BIOMOLECULAR NMR ASSIGNMENTS 1463 1% 0% 3
7 PROTEIN SCIENCE 1459 3% 0% 9
8 SEPARATION AND PURIFICATION METHODS 972 0% 1% 1
9 BIOCHEMISTRY 833 7% 0% 20
10 SCANDINAVIAN JOURNAL OF IMMUNOLOGY 723 2% 0% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LIGHT CHAIN AMYLOIDOSIS 894141 7% 41% 19 Search LIGHT+CHAIN+AMYLOIDOSIS Search LIGHT+CHAIN+AMYLOIDOSIS
2 GLYCOSYLATED IMMUNOGLOBULIN LIGHT CHAIN 455751 1% 100% 4 Search GLYCOSYLATED+IMMUNOGLOBULIN+LIGHT+CHAIN Search GLYCOSYLATED+IMMUNOGLOBULIN+LIGHT+CHAIN
3 IMMUNOLOGICAL SIGNAL 341813 1% 100% 3 Search IMMUNOLOGICAL+SIGNAL Search IMMUNOLOGICAL+SIGNAL
4 BENCE JONES PROTEIN 275630 6% 16% 15 Search BENCE+JONES+PROTEIN Search BENCE+JONES+PROTEIN
5 IMMUNOGLOBULIN LIGHT CHAIN 272316 5% 17% 14 Search IMMUNOGLOBULIN+LIGHT+CHAIN Search IMMUNOGLOBULIN+LIGHT+CHAIN
6 ANTIBODY AMYLOID 227875 1% 100% 2 Search ANTIBODY+AMYLOID Search ANTIBODY+AMYLOID
7 C L C L INTERDOMAIN INTERACTION 227875 1% 100% 2 Search C+L+C+L+INTERDOMAIN+INTERACTION Search C+L+C+L+INTERDOMAIN+INTERACTION
8 IMMUNOGLOBULIN LIGHT CHAIN LAMBDA 227875 1% 100% 2 Search IMMUNOGLOBULIN+LIGHT+CHAIN+LAMBDA Search IMMUNOGLOBULIN+LIGHT+CHAIN+LAMBDA
9 MDX 1097 227875 1% 100% 2 Search MDX+1097 Search MDX+1097
10 PROTEIN FOLDING AND AGGREGATION DISEASE 227875 1% 100% 2 Search PROTEIN+FOLDING+AND+AGGREGATION+DISEASE Search PROTEIN+FOLDING+AND+AGGREGATION+DISEASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 BADEN, EM , SIKKINK, LA , RAMIREZ-ALVARADO, M , (2009) LIGHT CHAIN AMYLOIDOSIS - CURRENT FINDINGS AND FUTURE PROSPECTS.CURRENT PROTEIN & PEPTIDE SCIENCE. VOL. 10. ISSUE 5. P. 500-508 44 58% 11
2 RAMIREZ-ALVARADO, M , (2012) AMYLOID FORMATION IN LIGHT CHAIN AMYLOIDOSIS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 12. ISSUE 22. P. 2523-2533 38 49% 7
3 BLANCAS-MEJIA, LM , HAMMERNIK, J , MARIN-ARGANY, M , RAMIREZ-ALVARADO, M , (2015) DIFFERENTIAL EFFECTS ON LIGHT CHAIN AMYLOID FORMATION DEPEND ON MUTATIONS AND TYPE OF GLYCOSAMINOGLYCANS.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 290. ISSUE 8. P. 4953 -4965 26 54% 3
4 BLANCAS-MEJIA, LM , TISCHER, A , THOMPSON, JR , TAI, J , WANG, L , AUTON, M , RAMIREZ-ALVARADO, M , (2014) KINETIC CONTROL IN PROTEIN FOLDING FOR LIGHT CHAIN AMYLOIDOSIS AND THE DIFFERENTIAL EFFECTS OF SOMATIC MUTATIONS.JOURNAL OF MOLECULAR BIOLOGY. VOL. 426. ISSUE 2. P. 347-361 25 58% 3
5 MORGAN, GJ , KELLY, JW , (2016) THE KINETIC STABILITY OF A FULL-LENGTH ANTIBODY LIGHT CHAIN DIMER DETERMINES WHETHER ENDOPROTEOLYSIS CAN RELEASE AMYLOIDOGENIC VARIABLE DOMAINS.JOURNAL OF MOLECULAR BIOLOGY. VOL. 428. ISSUE 21. P. 4280 -4297 23 47% 0
6 NOKWE, CN , HORA, M , ZACHARIAS, M , YAGI, H , PESCHEK, J , REIF, B , GOTO, Y , BUCHNER, J , (2016) A STABLE MUTANT PREDISPOSES ANTIBODY DOMAINS TO AMYLOID FORMATION THROUGH SPECIFIC NON-NATIVE INTERACTIONS.JOURNAL OF MOLECULAR BIOLOGY. VOL. 428. ISSUE 6. P. 1315 -1332 28 37% 0
7 STOPA, B , JAGUSIAK, A , KONIECZNY, L , PIEKARSKA, B , RYBARSKA, J , ZEMANEK, G , KROL, M , PIWOWAR, P , ROTERMAN, I , (2013) THE USE OF SUPRAMOLECULAR STRUCTURES AS PROTEIN LIGANDS.JOURNAL OF MOLECULAR MODELING. VOL. 19. ISSUE 11. P. 4731-4740 23 47% 1
8 BLANCAS-MEJIA, LM , RAMIREZ-ALVARADO, M , (2013) SYSTEMIC AMYLOIDOSES.ANNUAL REVIEW OF BIOCHEMISTRY, VOL 82. VOL. 82. ISSUE . P. 745-774 30 27% 41
9 MARIN-ARGANY, M , GUELL-BOSCH, J , BLANCAS-MEJIA, LM , VILLEGAS, S , RAMIREZ-ALVARADO, M , (2015) MUTATIONS CAN CAUSE LIGHT CHAINS TO BE TOO STABLE OR TOO UNSTABLE TO FORM AMYLOID FIBRILS.PROTEIN SCIENCE. VOL. 24. ISSUE 11. P. 1829 -1840 19 49% 0
10 RANDLES, EG , THOMPSON, JR , MARTIN, DJ , RAMIREZ-ALVARADO, M , (2009) STRUCTURAL ALTERATIONS WITHIN NATIVE AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS.JOURNAL OF MOLECULAR BIOLOGY. VOL. 389. ISSUE 1. P. 199-210 19 54% 12

Classes with closest relation at Level 1


Rank Class id link
1 7421 LIGHT CHAIN DEPOSITION DISEASE//FIBRILLARY GLOMERULONEPHRITIS//IMMUNOTACTOID GLOMERULOPATHY
2 403 AMYLOIDOSIS//AL AMYLOIDOSIS//CARDIAC AMYLOIDOSIS
3 2153 AMYLOID FIBRILS//AMYLOID//DIALYSIS RELATED AMYLOIDOSIS
4 8251 CANONICAL STRUCTURES//ANTIBODY MODELING//HUMANIZATION
5 5626 SERUM AMYLOID A//AMYLOID ENHANCING FACTOR//SAA
6 30760 ACIDIC OLIGOSACCHARIDE SUGAR CHAIN//HEPARIN DERIVED OLIGOSACCHARIDE//NEUROPATHOL S
7 6059 V H GENE//IMMUNOGLOBULIN GENES//CROSS REACTIVE IDIOTYPE
8 26217 ALPHA HEAVY CHAIN DISEASE//HEAVY CHAIN DISEASE//IMMUNOPROLIFERATIVE SMALL INTESTINAL DISEASE
9 4824 AGALACTOSYL IGG//MABS//PROT ANALYT CHEM
10 37475 ANTIBODY VARIABLE REGION//TRANSGENE SELECTION//COMMUNICATION DISTANCE

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