Class information for:
Level 1: NEUTROPHIL ELASTASE INHIBITOR//SIVELESTAT//NEUTROPHIL ELASTASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
24005 326 34.9 83%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
111 3       THROMBOSIS RESEARCH//THROMBOSIS AND HAEMOSTASIS//HEMATOLOGY 71244
1906 2             ALPHA 1 ANTITRYPSIN DEFICIENCY//ALPHA 1 ANTITRYPSIN//ALPHA1 ANTITRYPSIN DEFICIENCY 5908
24005 1                   NEUTROPHIL ELASTASE INHIBITOR//SIVELESTAT//NEUTROPHIL ELASTASE 326

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUTROPHIL ELASTASE INHIBITOR authKW 1835840 9% 70% 28
2 SIVELESTAT authKW 1720376 9% 61% 30
3 NEUTROPHIL ELASTASE authKW 697886 17% 13% 57
4 SIVELESTAT SODIUM HYDRATE authKW 544962 2% 73% 8
5 ONO 5046 authKW 499548 2% 67% 8
6 BIODEF MED address 407233 3% 43% 10
7 CAPSAICIN SENSITIVE SENSORY NEURONS authKW 306538 2% 55% 6
8 SIVELESTAT SODIUM authKW 249774 1% 67% 4
9 NEUTROPHIL ELASTASE ACTIVITY authKW 187332 1% 100% 2
10 REPROD ENGN address 105902 3% 10% 11

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Respiratory System 1121 16% 0% 51
2 Critical Care Medicine 939 11% 0% 35
3 Surgery 426 21% 0% 68
4 Gastroenterology & Hepatology 188 8% 0% 26
5 Pharmacology & Pharmacy 149 15% 0% 48
6 Hematology 113 6% 0% 21
7 Medicine, Research & Experimental 111 8% 0% 26
8 Peripheral Vascular Diseases 99 6% 0% 19
9 Transplantation 67 3% 0% 11
10 Cell Biology 60 9% 0% 29

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIODEF MED 407233 3% 43% 10
2 REPROD ENGN 105902 3% 10% 11
3 ALLERGY RHEUTMATOL 93666 0% 100% 1
4 ANATOM PATHOL PATHOL SCI 93666 0% 100% 1
5 BIOL DEV PROGRAM 93666 0% 100% 1
6 CLIN CHEM HAEMATOL MURINE 93666 0% 100% 1
7 ERIC BYWATERS MED 93666 0% 100% 1
8 INFLAMMAT IMMUN P EPITHELIUM GRP 93666 0% 100% 1
9 INFLAMMAT IMMUN P EPITHELIUM GRPINSERMU111 93666 0% 100% 1
10 INTERDISCIPLINARY ONCOO 93666 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GROWTH HORMONE & IGF RESEARCH 3012 2% 1% 6
2 TRANSLATIONAL RESEARCH 2442 2% 1% 5
3 SHOCK 2367 3% 0% 10
4 PULMONARY PHARMACOLOGY & THERAPEUTICS 2276 2% 0% 6
5 RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY 1798 1% 0% 4
6 EXPERIMENTAL LUNG RESEARCH 1319 2% 0% 5
7 JOURNAL OF INFLAMMATION 1184 0% 1% 1
8 JOURNAL OF ANESTHESIA 1044 1% 0% 4
9 JOURNAL OF INFLAMMATION-LONDON 967 1% 1% 2
10 CRITICAL CARE MEDICINE 956 3% 0% 11

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NEUTROPHIL ELASTASE INHIBITOR 1835840 9% 70% 28 Search NEUTROPHIL+ELASTASE+INHIBITOR Search NEUTROPHIL+ELASTASE+INHIBITOR
2 SIVELESTAT 1720376 9% 61% 30 Search SIVELESTAT Search SIVELESTAT
3 NEUTROPHIL ELASTASE 697886 17% 13% 57 Search NEUTROPHIL+ELASTASE Search NEUTROPHIL+ELASTASE
4 SIVELESTAT SODIUM HYDRATE 544962 2% 73% 8 Search SIVELESTAT+SODIUM+HYDRATE Search SIVELESTAT+SODIUM+HYDRATE
5 ONO 5046 499548 2% 67% 8 Search ONO+5046 Search ONO+5046
6 CAPSAICIN SENSITIVE SENSORY NEURONS 306538 2% 55% 6 Search CAPSAICIN+SENSITIVE+SENSORY+NEURONS Search CAPSAICIN+SENSITIVE+SENSORY+NEURONS
7 SIVELESTAT SODIUM 249774 1% 67% 4 Search SIVELESTAT+SODIUM Search SIVELESTAT+SODIUM
8 NEUTROPHIL ELASTASE ACTIVITY 187332 1% 100% 2 Search NEUTROPHIL+ELASTASE+ACTIVITY Search NEUTROPHIL+ELASTASE+ACTIVITY
9 ALPHA D GLUCOSYLGLYCEROL CALCITONIN GENE RELATED PEPTIDE 93666 0% 100% 1 Search ALPHA+D+GLUCOSYLGLYCEROL+CALCITONIN+GENE+RELATED+PEPTIDE Search ALPHA+D+GLUCOSYLGLYCEROL+CALCITONIN+GENE+RELATED+PEPTIDE
10 ANTIINFLAMMATORY AND ANYTIENZYMES DRUGS 93666 0% 100% 1 Search ANTIINFLAMMATORY+AND+ANYTIENZYMES+DRUGS Search ANTIINFLAMMATORY+AND+ANYTIENZYMES+DRUGS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 AIKAWA, N , KAWASAKI, Y , (2014) CLINICAL UTILITY OF THE NEUTROPHIL ELASTASE INHIBITOR SIVELESTAT FOR THE TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME.THERAPEUTICS AND CLINICAL RISK MANAGEMENT. VOL. 10. ISSUE . P. 621 -629 21 53% 9
2 TAO, W , MIAO, QB , ZHU, YB , SHU, YS , (2012) INHALED NEUTROPHIL ELASTASE INHIBITOR REDUCES OLEIC ACID-INDUCED ACUTE LUNG INJURY IN RATS.PULMONARY PHARMACOLOGY & THERAPEUTICS. VOL. 25. ISSUE 1. P. 99-103 16 67% 4
3 YAMAZAKI, S , TAKAYAMA, T , MORIGUCHI, M , HAYASHI, Y , MITSUKA, Y , YOSHIDA, N , HIGAKI, T , (2015) NEUTROPHIL ELASTASE INHIBITOR FOLLOWING LIVER RESECTION: A MATCHED COHORT STUDY.HEPATITIS MONTHLY. VOL. 15. ISSUE 11. P. - 15 65% 0
4 KAWAHARA, Y , NINOMIYA, I , FUJIMURA, T , FUNAKI, H , NAKAGAWARA, H , TAKAMURA, H , OYAMA, K , TAJIMA, H , FUSHIDA, S , INABA, H , ET AL (2010) PROSPECTIVE RANDOMIZED CONTROLLED STUDY ON THE EFFECTS OF PERIOPERATIVE ADMINISTRATION OF A NEUTROPHIL ELASTASE INHIBITOR TO PATIENTS UNDERGOING VIDEO-ASSISTED THORACOSCOPIC SURGERY FOR THORACIC ESOPHAGEAL CANCER.DISEASES OF THE ESOPHAGUS. VOL. 23. ISSUE 4. P. 329 -339 16 57% 18
5 NAGAI, Y , WATANABE, M , BABA, Y , IWATSUKI, M , HIRASHIMA, K , KARASHIMA, R , KURASHIGE, J , KINOSHITA, K , BABA, H , (2013) PREVENTIVE EFFECT OF SIVELESTAT ON POSTOPERATIVE RESPIRATORY DISORDERS AFTER THORACIC ESOPHAGECTOMY.SURGERY TODAY. VOL. 43. ISSUE 4. P. 361-366 13 62% 4
6 YAMAGUCHI, K , SUGASAWA, Y , TAKEUCHI, K , KUGIMIYA, T , KUMAKURA, S , IWANUMA, Y , KAJIYAMA, Y , TSURUMARU, M , NAGAOKA, I , INADA, E , (2011) EFFECTS OF SIVELESTAT ON BRONCHIAL INFLAMMATORY RESPONSES AFTER ESOPHAGECTOMY.INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. VOL. 28. ISSUE 2. P. 187-192 16 48% 5
7 WANG, ZQ , CHEN, LQ , YUAN, Y , WANG, WP , NIU, ZX , YANG, YS , CAI, J , (2015) EFFECTS OF NEUTROPHIL ELASTASE INHIBITOR IN PATIENTS UNDERGOING ESOPHAGECTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS.WORLD JOURNAL OF GASTROENTEROLOGY. VOL. 21. ISSUE 12. P. 3720 -3730 15 44% 1
8 ZEIHER, BG , MATSUOKA, S , KAWABATA, K , REPINE, JE , (2002) NEUTROPHIL ELASTASE AND ACUTE LUNG INJURY: PROSPECTS FOR SIVELESTAT AND OTHER NEUTROPHIL ELASTASE INHIBITORS AS THERAPEUTICS.CRITICAL CARE MEDICINE. VOL. 30. ISSUE 5. P. S281 -S287 18 47% 69
9 KIM, DH , CHUNG, JH , SON, BS , KIM, YJ , LEE, SG , (2014) EFFECT OF A NEUTROPHIL ELASTASE INHIBITOR ON VENTILATOR-INDUCED LUNG INJURY IN RATS.JOURNAL OF THORACIC DISEASE. VOL. 6. ISSUE 12. P. 1681 -1689 16 42% 1
10 PARK, JS , PARK, KH , KIM, H , CHOI, SY , (2014) EFFECTS OF SIVELESTAT TREATMENT ON ACUTE LUNG INJURY IN PARAQUAT-INTOXICATED RATS.DRUG AND CHEMICAL TOXICOLOGY. VOL. 37. ISSUE 1. P. 114-120 13 46% 3

Classes with closest relation at Level 1


Rank Class id link
1 13510 ELASTASE INHIBITOR//PROTEINASE K INHIBITOR//HUMAN LEUKOCYTE ELASTASE
2 7218 ELAFIN//SLPI//SECRETORY LEUKOCYTE PROTEASE INHIBITOR
3 34429 ACID ASPIRATION//GASTRIC ASPIRATION PNEUMONIA//PARTICULATE ASPIRATION
4 34661 INTEGRAT PHYSIOL CLIN SCI//MED SCI INTEGRAT PHYSIOL CLIN SCI//FU JEN CATHOLIC MED
5 36922 FR167653//BRAIN KOREA PROJECT TEAM NANOBIOMAT CELL BASED IM//CYTOKINE SUPPRESSANT
6 32913 TRANSEPITHELIAL MIGRATION//ALLERGY INFLAMMAT INFECT INFLAMMAT IMMUN//APICAL BASOLATERAL PLASMA MEMBRANES
7 4286 CIRCULATORY SHOCK//LUNG LYMPH FISTULA//OXYGEN DERIVED METABOLITES
8 9644 DISSEMINATED INTRAVASCULAR COAGULATION//DIC//SOLUBLE FIBRIN
9 21472 NEUTROPHIL MARGINATION//PULMONARY MICROCIRCULATION//BRONCHIAL TEMPERATURE
10 34371 H 1 SPIN LATTICE RELAXATION RATE//AFFINITY INDEX//LIGAND MACROMOLECULES INTERACTION

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