Class information for:
Level 1: TWEAK//FN14//STWEAK

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
21324 424 47.9 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
10 3       IMMUNOLOGY//JOURNAL OF IMMUNOLOGY//IMMUNOL 134299
854 2             CD40//BAFF//CD40 LIGAND 11643
21324 1                   TWEAK//FN14//STWEAK 424

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TWEAK authKW 7227275 31% 77% 131
2 FN14 authKW 5562150 21% 89% 87
3 STWEAK authKW 1440329 5% 100% 20
4 TUMOR NECROSIS FACTOR LIKE WEAK INDUCER OF APOPTOSIS authKW 610015 3% 71% 12
5 FIBROBLAST GROWTH FACTOR INDUCIBLE 14 authKW 504115 2% 100% 7
6 FIBROBLAST GROWTH FACTOR INDUCIBLE 14 FN14 authKW 432099 1% 100% 6
7 TUMOR NECROSIS FACTOR LIKE WEAK INDUCER OF APOPTOSIS TWEAK authKW 360082 1% 100% 5
8 TWEAKR authKW 360082 1% 100% 5
9 UNIT DETECT TREATMENT ATHEROTHROMBOT DIS address 216049 1% 100% 3
10 TNF LIKE WEAK INDUCER OF APOPTOSIS authKW 162036 1% 75% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 855 23% 0% 96
2 Urology & Nephrology 499 11% 0% 45
3 Cell Biology 438 18% 0% 76
4 Biochemistry & Molecular Biology 226 23% 0% 96
5 Oncology 139 11% 0% 48
6 Medicine, Research & Experimental 117 7% 0% 31
7 Rheumatology 99 3% 0% 13
8 Peripheral Vascular Diseases 78 5% 0% 20
9 Pathology 59 4% 0% 17
10 Cardiac & Cardiovascular System 52 6% 0% 24

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UNIT DETECT TREATMENT ATHEROTHROMBOT DIS 216049 1% 100% 3
2 VASC INFLAMMATORY DIS 149709 6% 9% 24
3 OTOLARYNGOL DIS GRP HJ23 144033 0% 100% 2
4 VASC EACH 144033 0% 100% 2
5 PULM PHARMACOTHER Y 108022 1% 50% 3
6 EXPLORATORY SCI 99706 1% 23% 6
7 BIOMED NETWORK DIABET ASSOCIATED METAB 96021 0% 67% 2
8 SKELETAL MUSCLE PHYSIOL NEUROBIOL 96021 0% 67% 2
9 ANETESIOL REANIMAT 72016 0% 100% 1
10 AUTOIMMUN DRUG DISCOVERY 72016 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FRONTIERS IN IMMUNOLOGY 3556 3% 0% 12
2 CYTOKINE 2332 3% 0% 12
3 MOLECULAR CANCER RESEARCH 956 1% 0% 5
4 BMC NEPHROLOGY 891 1% 0% 4
5 CYTOKINE & GROWTH FACTOR REVIEWS 804 1% 0% 3
6 CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 640 1% 0% 5
7 EUROPEAN JOURNAL OF INFLAMMATION 578 0% 0% 2
8 FRONTIERS IN BIOSCIENCE-LANDMARK 495 1% 0% 5
9 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 475 2% 0% 7
10 ARTHRITIS RESEARCH 394 0% 1% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TWEAK 7227275 31% 77% 131 Search TWEAK Search TWEAK
2 FN14 5562150 21% 89% 87 Search FN14 Search FN14
3 STWEAK 1440329 5% 100% 20 Search STWEAK Search STWEAK
4 TUMOR NECROSIS FACTOR LIKE WEAK INDUCER OF APOPTOSIS 610015 3% 71% 12 Search TUMOR+NECROSIS+FACTOR+LIKE+WEAK+INDUCER+OF+APOPTOSIS Search TUMOR+NECROSIS+FACTOR+LIKE+WEAK+INDUCER+OF+APOPTOSIS
5 FIBROBLAST GROWTH FACTOR INDUCIBLE 14 504115 2% 100% 7 Search FIBROBLAST+GROWTH+FACTOR+INDUCIBLE+14 Search FIBROBLAST+GROWTH+FACTOR+INDUCIBLE+14
6 FIBROBLAST GROWTH FACTOR INDUCIBLE 14 FN14 432099 1% 100% 6 Search FIBROBLAST+GROWTH+FACTOR+INDUCIBLE+14+FN14 Search FIBROBLAST+GROWTH+FACTOR+INDUCIBLE+14+FN14
7 TUMOR NECROSIS FACTOR LIKE WEAK INDUCER OF APOPTOSIS TWEAK 360082 1% 100% 5 Search TUMOR+NECROSIS+FACTOR+LIKE+WEAK+INDUCER+OF+APOPTOSIS+TWEAK Search TUMOR+NECROSIS+FACTOR+LIKE+WEAK+INDUCER+OF+APOPTOSIS+TWEAK
8 TWEAKR 360082 1% 100% 5 Search TWEAKR Search TWEAKR
9 TNF LIKE WEAK INDUCER OF APOPTOSIS 162036 1% 75% 3 Search TNF+LIKE+WEAK+INDUCER+OF+APOPTOSIS Search TNF+LIKE+WEAK+INDUCER+OF+APOPTOSIS
10 14 FN14 144033 0% 100% 2 Search 14+FN14 Search 14+FN14

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 WAJANT, H , (2013) THE TWEAK-FN14 SYSTEM AS A POTENTIAL DRUG TARGET.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 170. ISSUE 4. P. 748-764 101 82% 20
2 CHENG, E , ARMSTRONG, CL , GALISTEO, R , WINKLES, JA , (2013) TWEAK/FN14 AXIS-TARGETED THERAPEUTICS: MOVING BASIC SCIENCE DISCOVERIES TO THE CLINIC.FRONTIERS IN IMMUNOLOGY. VOL. 4. ISSUE . P. - 88 68% 11
3 SANZ, AB , SANCHEZ-NINO, MD , ORTIZ, A , (2011) TWEAK, A MULTIFUNCTIONAL CYTOKINE IN KIDNEY INJURY.KIDNEY INTERNATIONAL. VOL. 80. ISSUE 7. P. 708 -718 81 76% 25
4 BURKLY, LC , MICHAELSON, JS , ZHENG, TS , (2011) TWEAK/FN14 PATHWAY: AN IMMUNOLOGICAL SWITCH FOR SHAPING TISSUE RESPONSES.IMMUNOLOGICAL REVIEWS. VOL. 244. ISSUE . P. 99-114 67 78% 72
5 WINKLES, JA , (2008) THE TWEAK - FN14 CYTOKINE-RECEPTOR AXIS: DISCOVERY, BIOLOGY AND THERAPEUTIC TARGETING.NATURE REVIEWS DRUG DISCOVERY. VOL. 7. ISSUE 5. P. 411 -425 74 59% 254
6 SANZ, AB , IZQUIERDO, MC , SANCHEZ-NINO, MD , UCERO, AC , EGIDO, J , RUIZ-ORTEGA, M , RAMOS, AM , PUTTERMAN, C , ORTIZ, A , (2014) TWEAK AND THE PROGRESSION OF RENAL DISEASE: CLINICAL TRANSLATION.NEPHROLOGY DIALYSIS TRANSPLANTATION. VOL. 29. ISSUE . P. I54-I62 55 80% 13
7 ARMSTRONG, CL , GALISTEO, R , BROWN, SAN , WINKLES, JA , (2016) TWEAK ACTIVATION OF THE NON-CANONICAL NF-KAPPA B SIGNALING PATHWAY DIFFERENTIALLY REGULATES MELANOMA AND PROSTATE CANCER CELL INVASION.ONCOTARGET. VOL. 7. ISSUE 49. P. 81474 -81492 58 81% 0
8 DOHI, T , BURKLY, LC , (2012) THE TWEAK/FN14 PATHWAY AS AN AGGRAVATING AND PERPETUATING FACTOR IN INFLAMMATORY DISEASES; FOCUS ON INFLAMMATORY BOWEL DISEASES.JOURNAL OF LEUKOCYTE BIOLOGY. VOL. 92. ISSUE 2. P. 265 -279 67 63% 26
9 SHARIF, MN , CAMPANHOLLE, G , NAGIEC, EE , WANG, J , SYED, J , O'NEIL, SP , ZHAN, YT , BRENNEMAN, K , HOMER, B , NEUBERT, H , ET AL (2016) SOLUBLE FN14 IS DETECTED AND ELEVATED IN MOUSE AND HUMAN KIDNEY DISEASE.PLOS ONE. VOL. 11. ISSUE 5. P. - 51 76% 0
10 ORTIZ, A , SANZ, AB , GARCIA, BM , MORENO, JA , NINO, MDS , MARTIN-VENTURA, JL , EGIDO, J , BLANCO-COLIO, LM , (2009) CONSIDERING TWEAK AS A TARGET FOR THERAPY IN RENAL AND VASCULAR INJURY.CYTOKINE & GROWTH FACTOR REVIEWS. VOL. 20. ISSUE 3. P. 251-258 58 72% 27

Classes with closest relation at Level 1


Rank Class id link
1 22230 DCR3//DECOY RECEPTOR 3//TL1A
2 10318 HAPTOGLOBIN//CD163//HAPTOGLOBIN PHENOTYPE
3 8273 BAFF//APRIL//BLYS
4 8433 MURF1//ATROGIN 1//MUSCLE WASTING
5 24952 PHARMACEUT PROTE//TNFR2//TNF DEFICIENCY
6 17952 TRAF4//TRAF6//TRAF2
7 36251 CELL RECOGNIT PONSE//I KAPPA B ZETA//I KAPPA B XI
8 28577 CXCL16//CXCR6//SR PSOX
9 7566 GLOMERULONEPHRITIS//INFLAMMATORY DIS//NEPHROTOXIC NEPHRITIS
10 10004 NECROPTOSIS//RIP3//RIP1

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