Class information for:
Level 1: PHARMACEUT PROTE//TNFR2//TNF DEFICIENCY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
24952 296 50.9 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
10 3       IMMUNOLOGY//JOURNAL OF IMMUNOLOGY//IMMUNOL 134299
854 2             CD40//BAFF//CD40 LIGAND 11643
24952 1                   PHARMACEUT PROTE//TNFR2//TNF DEFICIENCY 296

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACEUT PROTE address 362300 4% 29% 12
2 TNFR2 authKW 217388 5% 15% 14
3 TNF DEFICIENCY authKW 206319 1% 100% 2
4 TNFR1 SELECTIVE ANTAGONIST authKW 206319 1% 100% 2
5 XENP1595 authKW 206319 1% 100% 2
6 BACILLUS CALMETTE GUERIN address 137545 1% 67% 2
7 PRE LIGAND BINDING ASSEMBLY DOMAIN PLAD authKW 137545 1% 67% 2
8 6 CHLOROEMODIC ACID authKW 103160 0% 100% 1
9 A1 MODULE authKW 103160 0% 100% 1
10 AFFINITY MALDI authKW 103160 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 1840 38% 0% 113
2 Cell Biology 292 18% 0% 52
3 Biochemistry & Molecular Biology 264 28% 0% 82
4 Rheumatology 206 5% 0% 15
5 Medicine, Research & Experimental 105 8% 0% 24
6 Chemistry, Medicinal 53 5% 0% 14
7 Pathology 20 3% 0% 9
8 Infectious Diseases 17 3% 0% 9
9 Neurosciences 12 6% 0% 19
10 Biophysics 11 3% 0% 10

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACEUT PROTE 362300 4% 29% 12
2 BACILLUS CALMETTE GUERIN 137545 1% 67% 2
3 BIOL FUNCT MED CONTROL 103160 0% 100% 1
4 CLIN IMMUNOPATHOLFED STATE BUDGETARY R 103160 0% 100% 1
5 EXPT MOL IMMUNOL NEUROGENET UMR7355 103160 0% 100% 1
6 IEM MOL IMMUNOL EMBRYOL 103160 0% 100% 1
7 IMMUNL CELL BIOL 103160 0% 100% 1
8 INSERM CNRS U1043 103160 0% 100% 1
9 IRCBC 103160 0% 100% 1
10 PHYSIOPATHOL CELLULAIRE MOL RETINA 103160 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYTOKINE & GROWTH FACTOR REVIEWS 3214 2% 1% 5
2 BIOMEDICINE 1662 0% 2% 1
3 JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS 1282 1% 1% 2
4 JOURNAL OF IMMUNOLOGY 1181 8% 0% 25
5 EUROPEAN JOURNAL OF IMMUNOLOGY 1116 4% 0% 12
6 SCIENCE SIGNALING 596 1% 0% 3
7 ARTHRITIS RESEARCH & THERAPY 499 1% 0% 4
8 FUTURE MEDICINAL CHEMISTRY 448 1% 0% 2
9 ENDOSKOPIE HEUTE 423 0% 0% 1
10 EUROPEAN CYTOKINE NETWORK 416 1% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TNFR2 217388 5% 15% 14 Search TNFR2 Search TNFR2
2 TNF DEFICIENCY 206319 1% 100% 2 Search TNF+DEFICIENCY Search TNF+DEFICIENCY
3 TNFR1 SELECTIVE ANTAGONIST 206319 1% 100% 2 Search TNFR1+SELECTIVE+ANTAGONIST Search TNFR1+SELECTIVE+ANTAGONIST
4 XENP1595 206319 1% 100% 2 Search XENP1595 Search XENP1595
5 PRE LIGAND BINDING ASSEMBLY DOMAIN PLAD 137545 1% 67% 2 Search PRE+LIGAND+BINDING+ASSEMBLY+DOMAIN+PLAD Search PRE+LIGAND+BINDING+ASSEMBLY+DOMAIN+PLAD
6 6 CHLOROEMODIC ACID 103160 0% 100% 1 Search 6+CHLOROEMODIC+ACID Search 6+CHLOROEMODIC+ACID
7 A1 MODULE 103160 0% 100% 1 Search A1+MODULE Search A1+MODULE
8 AFFINITY MALDI 103160 0% 100% 1 Search AFFINITY+MALDI Search AFFINITY+MALDI
9 AMINOPEPTIDASE P3 103160 0% 100% 1 Search AMINOPEPTIDASE+P3 Search AMINOPEPTIDASE+P3
10 ANTI ENDOTHELIAL RESPONSE 103160 0% 100% 1 Search ANTI+ENDOTHELIAL+RESPONSE Search ANTI+ENDOTHELIAL+RESPONSE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 VAN HAUWERMEIREN, F , VANDENBROUCKE, RE , LIBERT, C , (2011) TREATMENT OF TNF MEDIATED DISEASES BY SELECTIVE INHIBITION OF SOLUBLE TNF OR TNFR1.CYTOKINE & GROWTH FACTOR REVIEWS. VOL. 22. ISSUE 5-6. P. 311 -319 33 31% 44
2 RICHTER, F , LIEBIG, T , GUENZI, E , HERRMANN, A , SCHEURICH, P , PFIZENMAIER, K , KONTERMANN, RE , (2013) ANTAGONISTIC TNF RECEPTOR ONE-SPECIFIC ANTIBODY (ATROSAB): RECEPTOR BINDING AND IN VITRO BIOACTIVITY.PLOS ONE. VOL. 8. ISSUE 8. P. - 22 36% 6
3 RICHTER, C , MESSERSCHMIDT, S , HOLEITER, G , TEPPERINK, J , OSSWALD, S , ZAPPE, A , BRANSCHADEL, M , BOSCHERT, V , MANN, DA , SCHEURICH, P , ET AL (2012) THE TUMOR NECROSIS FACTOR RECEPTOR STALK REGIONS DEFINE RESPONSIVENESS TO SOLUBLE VERSUS MEMBRANE-BOUND LIGAND.MOLECULAR AND CELLULAR BIOLOGY. VOL. 32. ISSUE 13. P. 2515 -2529 25 32% 9
4 BRAMBILLA, R , ASHBAUGH, JJ , MAGLIOZZI, R , DELLAROLE, A , KARMALLY, S , SZYMKOWSKI, DE , BETHEA, JR , (2011) INHIBITION OF SOLUBLE TUMOUR NECROSIS FACTOR IS THERAPEUTIC IN EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS AND PROMOTES AXON PRESERVATION AND REMYELINATION.BRAIN. VOL. 134. ISSUE . P. 2736 -2754 21 35% 43
5 OLLEROS, ML , CHAVEZ-GALAN, L , SEGUENI, N , BOURIGAULT, ML , VESIN, D , GARCIA, I , NEDOSPASOV, SA , QUESNIAUX, VFJ , RYFFEL, B , ERARD, F , ET AL (2015) CONTROL OF MYCOBACTERIAL INFECTIONS IN MICE EXPRESSING HUMAN TUMOR NECROSIS FACTOR (TNF) BUT NOT MOUSE TNF.INFECTION AND IMMUNITY. VOL. 83. ISSUE 9. P. 3612 -3623 17 43% 0
6 MUKAI, Y , NAKAMURA, T , YOSHIKAWA, M , YOSHIOKA, Y , TSUNODA, S , NAKAGAWA, S , YAMAGATA, Y , TSUTSUMI, Y , (2010) SOLUTION OF THE STRUCTURE OF THE TNF-TNFR2 COMPLEX.SCIENCE SIGNALING. VOL. 3. ISSUE 148. P. - 22 32% 42
7 PROBERT, L , (2015) TNF AND ITS RECEPTORS IN THE CNS: THE ESSENTIAL, THE DESIRABLE AND THE DELETERIOUS EFFECTS.NEUROSCIENCE. VOL. 302. ISSUE . P. 2 -22 31 14% 30
8 WILLIAMS, SK , MAIER, O , FISCHER, R , FAIRLESS, R , HOCHMEISTER, S , STOJIC, A , PICK, L , HAAR, D , MUSIOL, S , STORCH, MK , ET AL (2014) ANTIBODY-MEDIATED INHIBITION OF TNFR1 ATTENUATES DISEASE IN A MOUSE MODEL OF MULTIPLE SCLEROSIS.PLOS ONE. VOL. 9. ISSUE 2. P. - 17 36% 6
9 OLLEROS, ML , VESIN, D , BISIG, R , SANTIAGO-RABER, ML , SCHUEPBACH-MALLEPELL, S , KOLLIAS, G , GAIDE, O , GARCIA, I , (2012) MEMBRANE-BOUND TNF INDUCES PROTECTIVE IMMUNE RESPONSES TO M. BOVIS BCG INFECTION: REGULATION OF MEMTNF AND TNF RECEPTORS COMPARING TWO MEMTNF MOLECULES.PLOS ONE. VOL. 7. ISSUE 5. P. - 14 45% 9
10 PERRIER, C , DE HERTOGH, G , CREMER, J , VERMEIRE, S , RUTGEERTS, P , VAN ASSCHE, G , SZYMKOWSKI, DE , CEUPPENS, JL , (2013) NEUTRALIZATION OF MEMBRANE TNF, BUT NOT SOLUBLE TNF, IS CRUCIAL FOR THE TREATMENT OF EXPERIMENTAL COLITIS.INFLAMMATORY BOWEL DISEASES. VOL. 19. ISSUE 2. P. 246-253 14 40% 18

Classes with closest relation at Level 1


Rank Class id link
1 645 TUMOR NECROSIS FACTOR//TNF RECEPTOR//MORRIS HEPATOMA 5123
2 26875 APO 1 ANTIBODY//APO I FAS APOPTOSIS//APOPTOSIS CYTOKINES
3 22707 MULTIPLE SCLEROSIS//SOLUBLE VASCULAR CELL ADHESION MOLECULES//GRP MULTIPLE SCLEROSIS NEUROIMMUNOL
4 16155 INFLIXIMAB//DRUG INDUCED LUPUS//ADALIMUMAB
5 10449 LYMPHOTOXIN//BTLA//TERTIARY LYMPHOID ORGANS
6 17952 TRAF4//TRAF6//TRAF2
7 22230 DCR3//DECOY RECEPTOR 3//TL1A
8 31640 ANGIOTENSIN II VACCINE//EA4222//KINOID
9 17059 CONCANAVALIN A//D GALACTOSAMINE//D GALN LPS
10 10004 NECROPTOSIS//RIP3//RIP1

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