Class information for:
Level 1: NABUMETONE//6 METHOXY 2 NAPHTHYLACETIC ACID//NAPROXEN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
20630 451 23.0 51%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
275 3       NSAIDS//CYCLOOXYGENASE//CYCLOOXYGENASE 2 43399
466 2             NSAIDS//NON STEROIDAL ANTI INFLAMMATORY DRUGS//COX 2 INHIBITORS 15930
20630 1                   NABUMETONE//6 METHOXY 2 NAPHTHYLACETIC ACID//NAPROXEN 451

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NABUMETONE authKW 1794741 12% 49% 54
2 6 METHOXY 2 NAPHTHYLACETIC ACID authKW 498551 2% 82% 9
3 NAPROXEN authKW 289056 14% 7% 64
4 CAS 26159 34 2 authKW 203115 1% 100% 3
5 6MNA authKW 135410 0% 100% 2
6 APRENINR authKW 135410 0% 100% 2
7 CAS 104124 26 7 authKW 135410 0% 100% 2
8 LIQUID CAPSULES authKW 135410 0% 100% 2
9 S NAPROXEN BETAINATE SODIUM SALT MONOHYDRATE authKW 135410 0% 100% 2
10 NAPROXEN DETERMINATION authKW 121866 1% 60% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 2621 45% 0% 202
2 Rheumatology 2431 14% 0% 61
3 Chemistry, Analytical 845 20% 0% 88
4 Medicine, General & Internal 302 13% 0% 60
5 Toxicology 139 6% 0% 27
6 Medicine, Research & Experimental 125 7% 0% 33
7 Biochemical Research Methods 114 6% 0% 28
8 Chemistry, Medicinal 40 4% 0% 16
9 Electrochemistry 11 2% 0% 9
10 Geriatrics & Gerontology 6 1% 0% 4

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ETH DRUGS 67705 0% 100% 1
2 OUTCOMES W2E 50 67705 0% 100% 1
3 PDEA 67705 0% 100% 1
4 RUMENT DEV OURCES 67705 0% 100% 1
5 SHOUNAN HIRATUKA PHARM 67705 0% 100% 1
6 ACCELERA UNIT 33851 0% 50% 1
7 CABRINI HOSP PUBL HLTH PREVENT MED 33851 0% 50% 1
8 ESTUDIOS CIENT CLIN PHARMA 33851 0% 50% 1
9 INTERNAL MED RHEUMATOL MED 22567 0% 33% 1
10 POND ST 22567 0% 33% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 REVISTA BRASILEIRA DE MEDICINA 33839 2% 7% 7
2 EUROPEAN JOURNAL OF RHEUMATOLOGY AND INFLAMMATION 15222 1% 4% 6
3 INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS 5005 4% 0% 17
4 DRUGS 4811 4% 0% 20
5 RHEUMATOLOGY AND REHABILITATION 4681 1% 2% 3
6 CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL 4067 4% 0% 17
7 PHARMATHERAPEUTICA 3431 1% 1% 4
8 AMERICAN JOURNAL OF MEDICINE 3183 5% 0% 23
9 INVESTIGACION MEDICA INTERNACIONAL 3039 0% 2% 2
10 BAILLIERES CLINICAL RHEUMATOLOGY 2399 1% 1% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NABUMETONE 1794741 12% 49% 54 Search NABUMETONE Search NABUMETONE
2 6 METHOXY 2 NAPHTHYLACETIC ACID 498551 2% 82% 9 Search 6+METHOXY+2+NAPHTHYLACETIC+ACID Search 6+METHOXY+2+NAPHTHYLACETIC+ACID
3 NAPROXEN 289056 14% 7% 64 Search NAPROXEN Search NAPROXEN
4 CAS 26159 34 2 203115 1% 100% 3 Search CAS+26159+34+2 Search CAS+26159+34+2
5 6MNA 135410 0% 100% 2 Search 6MNA Search 6MNA
6 APRENINR 135410 0% 100% 2 Search APRENINR Search APRENINR
7 CAS 104124 26 7 135410 0% 100% 2 Search CAS+104124+26+7 Search CAS+104124+26+7
8 LIQUID CAPSULES 135410 0% 100% 2 Search LIQUID+CAPSULES Search LIQUID+CAPSULES
9 S NAPROXEN BETAINATE SODIUM SALT MONOHYDRATE 135410 0% 100% 2 Search S+NAPROXEN+BETAINATE+SODIUM+SALT+MONOHYDRATE Search S+NAPROXEN+BETAINATE+SODIUM+SALT+MONOHYDRATE
10 NAPROXEN DETERMINATION 121866 1% 60% 3 Search NAPROXEN+DETERMINATION Search NAPROXEN+DETERMINATION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 FRIEDEL, HA , TODD, PA , (1988) NABUMETONE - A PRELIMINARY REVIEW OF ITS PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES, AND THERAPEUTIC EFFICACY IN RHEUMATIC DISEASES.DRUGS. VOL. 35. ISSUE 5. P. 504-524 40 100% 36
2 FRIEDEL, HA , LANGTRY, HD , BUCKLEY, MM , (1993) NABUMETONE - A REAPPRAISAL OF ITS PHARMACOLOGY AND THERAPEUTIC USE IN RHEUMATIC DISEASES.DRUGS. VOL. 45. ISSUE 1. P. 131-156 35 80% 38
3 ELSINGHORST, PW , KINZIG, M , RODAMER, M , HOLZGRABE, U , SORGEL, F , (2011) AN LC-MS/MS PROCEDURE FOR THE QUANTIFICATION OF NAPROXEN IN HUMAN PLASMA: DEVELOPMENT, VALIDATION, COMPARISON WITH OTHER METHODS, AND APPLICATION TO A PHARMACOKINETIC STUDY.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 879. ISSUE 19. P. 1686 -1696 27 53% 19
4 ALIZADEH, N , KEYHANIAN, F , (2015) SIMPLE, SENSITIVE AND SELECTIVE SPECTROPHOTOMETRIC ASSAY OF NAPROXEN IN PURE, PHARMACEUTICAL PREPARATION AND HUMAN SERUM SAMPLES.ACTA POLONIAE PHARMACEUTICA. VOL. 72. ISSUE 5. P. 867 -875 18 69% 0
5 DAVIES, NM , ANDERSON, KE , (1997) CLINICAL PHARMACOKINETICS OF NAPROXEN.CLINICAL PHARMACOKINETICS. VOL. 32. ISSUE 4. P. 268-293 39 44% 50
6 TODD, PA , CLISSOLD, SP , (1990) NAPROXEN - A REAPPRAISAL OF ITS PHARMACOLOGY, AND THERAPEUTIC USE IN RHEUMATIC DISEASES AND PAIN STATES.DRUGS. VOL. 40. ISSUE 1. P. 91-137 71 26% 116
7 NOBILIS, M , MIKUSEK, J , SZOTAKOVA, B , JIRASKO, R , HOLCAPEK, M , CHAMSEDDIN, C , JIRA, T , KUCERA, R , KUNES, J , POUR, M , (2013) ANALYTICAL POWER OF LLE-HPLC-PDA-MS/MS IN DRUG METABOLISM STUDIES: IDENTIFICATION OF NEW NABUMETONE METABOLITES.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. VOL. 80. ISSUE . P. 164-172 14 70% 6
8 SOMA, LR , UBOH, CE , RUDY, JA , SMITH, MS , (1996) DISPOSITION AND EXCRETION OF 6-METHOXY-2-NAPHTHYLACETIC ACID, THE ACTIVE METABOLITE OF NABUMETONE IN HORSES.AMERICAN JOURNAL OF VETERINARY RESEARCH. VOL. 57. ISSUE 4. P. 517-521 20 83% 4
9 NOBILIS, M , KOPECKY, J , KVETINA, J , SVOBODA, Z , POUR, M , KUNES, J , HOLCAPEK, M , KOLAROVA, L , (2003) COMPARATIVE BIOTRANSFORMATION AND DISPOSITION STUDIES OF NABUMETONE IN HUMANS AND MINIPIGS USING HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY WITH ULTRAVIOLET, FLUORESCENCE AND MASS SPECTROMETRIC DETECTION.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. VOL. 32. ISSUE 4-5. P. 641-656 14 88% 34
10 SVETLIK, S , STICHA, M , MATOUSKOVA, O , NESPESNA, L , SKLENAR, Z , BARTUNEK, A , PERLIK, F , SLANAR, O , (2016) NABUMETONE AND 6-MNA PHARMACOKINETICS, ASSESSMENT OF INTRASUBJECT VARIABILITY AND GENDER EFFECT.AMERICAN JOURNAL OF THERAPEUTICS. VOL. 23. ISSUE 6. P. E1498 -E1503 12 75% 0

Classes with closest relation at Level 1


Rank Class id link
1 17116 ETODOLAC//EUROPEAN JOURNAL OF RHEUMATOLOGY AND INFLAMMATION//CAS 41340 25 4
2 25566 OXAPROZIN//4 5 DIARYLOXAZOLE//4 ACETAMIDOPHENYL 2 5 P TOLUYL 1 METHYLPYRROLEACETATE PHARMACOKINETICS
3 7453 CHIRAL INVERSION//DEXIBUPROFEN//IBUPROFEN
4 13403 ACECLOFENAC//ETHAMSYLATE//MEFENAMIC ACID
5 15959 MELOXICAM//TENOXICAM//PIROXICAM
6 33459 CHONDROITIN SULFATE B CSB//HBS GENE//SERV CLIN MALAD INFECT
7 1326 NSAIDS//NON STEROIDAL ANTI INFLAMMATORY DRUGS//LOW DOSE ASPIRIN
8 34996 ACTIVE CENTER ANALOGS OF SUPEROXIDE DISMUTASE//COFPLATON//COFPROPAMINE
9 9386 PAIN NUFFIELD ANAESTHET//THIRD MOLAR SURGERY//DENTAL PAIN
10 34344 BEHAVIORAL RATER TRAINING//INFANT BEHAVIOR CODING//TRAIT THEORY

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