Class information for:
Level 1: LYSYL HYDROXYLASE//EHLERS DANLOS SYNDROME TYPE VI//AGEN UNIT

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
17301 607 35.6 63%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
593 3       JOURNAL OF THE AMERICAN LEATHER CHEMISTS ASSOCIATION//OSTEOGENESIS IMPERFECTA//JOURNAL OF THE SOCIETY OF LEATHER TECHNOLOGISTS AND CHEMISTS 14947
797 2             OSTEOGENESIS IMPERFECTA//EHLERS DANLOS SYNDROME//COLLAGEN 12085
17301 1                   LYSYL HYDROXYLASE//EHLERS DANLOS SYNDROME TYPE VI//AGEN UNIT 607

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LYSYL HYDROXYLASE authKW 1303863 6% 72% 36
2 EHLERS DANLOS SYNDROME TYPE VI authKW 419198 2% 83% 10
3 AGEN UNIT address 389127 7% 18% 42
4 PROLYL 4 HYDROXYLASE authKW 311938 4% 24% 26
5 LYSYL HYDROXYLASE DEFICIENCY authKW 251521 1% 100% 5
6 LYSINE HYDROXYLATION authKW 226366 1% 75% 6
7 2 OXOGLUTARATE 5 DIOXYGENASE authKW 201217 1% 100% 4
8 PROCOLLAGEN LYSINE authKW 201217 1% 100% 4
9 PROLYL 4 HYDROXYLASE ALPHA 1 authKW 201217 1% 100% 4
10 HYDROXYLYSINE authKW 168443 2% 28% 12

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 2138 50% 0% 301
2 Biophysics 475 11% 0% 67
3 Cell Biology 332 14% 0% 83
4 Dermatology 178 5% 0% 28
5 Genetics & Heredity 101 7% 0% 41
6 Medicine, Research & Experimental 79 5% 0% 33
7 Orthopedics 67 3% 0% 21
8 Clinical Neurology 47 5% 0% 33
9 Endocrinology & Metabolism 37 4% 0% 26
10 Biochemical Research Methods 33 3% 0% 21

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AGEN UNIT 389127 7% 18% 42
2 SANATORIUM CHIBA 100608 0% 100% 2
3 NC ORAL HLTH 90539 1% 30% 6
4 NORTH CAROLINA ORAL HLTH 80482 1% 40% 4
5 DENT CB 7455 67071 0% 67% 2
6 EPIGENET EDITING GRP 67071 0% 67% 2
7 MATRIX GRP 67071 0% 67% 2
8 CONNECT TISSUE UNIT 67063 1% 22% 6
9 231 BETHESDA AVEML 527 50304 0% 100% 1
10 ANTIBODIES FC RECEPTORS CLIN PONSES TEAM 50304 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MATRIX BIOLOGY 16489 3% 2% 21
2 CONNECTIVE TISSUE RESEARCH 7244 3% 1% 16
3 COLLAGEN AND RELATED RESEARCH 3983 1% 2% 5
4 PROCEEDINGS OF THE ASSOCIATION OF AMERICAN PHYSICIANS 1880 0% 1% 3
5 BIOCHEMICAL JOURNAL 1619 5% 0% 31
6 JOURNAL OF BIOLOGICAL CHEMISTRY 1509 11% 0% 69
7 BIOCHIMICA ET BIOPHYSICA ACTA 1338 5% 0% 28
8 MUTATION RESEARCH-GENOMICS 1288 0% 3% 1
9 JOURNAL OF INVESTIGATIVE DERMATOLOGY 1052 2% 0% 15
10 EXPERIMENTELLE PATHOLOGIE 851 0% 2% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LYSYL HYDROXYLASE 1303863 6% 72% 36 Search LYSYL+HYDROXYLASE Search LYSYL+HYDROXYLASE
2 EHLERS DANLOS SYNDROME TYPE VI 419198 2% 83% 10 Search EHLERS+DANLOS+SYNDROME+TYPE+VI Search EHLERS+DANLOS+SYNDROME+TYPE+VI
3 PROLYL 4 HYDROXYLASE 311938 4% 24% 26 Search PROLYL+4+HYDROXYLASE Search PROLYL+4+HYDROXYLASE
4 LYSYL HYDROXYLASE DEFICIENCY 251521 1% 100% 5 Search LYSYL+HYDROXYLASE+DEFICIENCY Search LYSYL+HYDROXYLASE+DEFICIENCY
5 LYSINE HYDROXYLATION 226366 1% 75% 6 Search LYSINE+HYDROXYLATION Search LYSINE+HYDROXYLATION
6 2 OXOGLUTARATE 5 DIOXYGENASE 201217 1% 100% 4 Search 2+OXOGLUTARATE+5+DIOXYGENASE Search 2+OXOGLUTARATE+5+DIOXYGENASE
7 PROCOLLAGEN LYSINE 201217 1% 100% 4 Search PROCOLLAGEN+LYSINE Search PROCOLLAGEN+LYSINE
8 PROLYL 4 HYDROXYLASE ALPHA 1 201217 1% 100% 4 Search PROLYL+4+HYDROXYLASE+ALPHA+1 Search PROLYL+4+HYDROXYLASE+ALPHA+1
9 HYDROXYLYSINE 168443 2% 28% 12 Search HYDROXYLYSINE Search HYDROXYLYSINE
10 COLLAGEN BIOSYNTHESIS 154551 2% 24% 13 Search COLLAGEN+BIOSYNTHESIS Search COLLAGEN+BIOSYNTHESIS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 MYLLYHARJU, J , (2005) INTRACELLULAR POST-TRANSLATIONAL MODIFICATIONS OF COLLAGENS.COLLAGEN. VOL. 247. ISSUE . P. 115 -147 84 57% 28
2 GJALTEMA, RAF , BANK, RA , (2017) MOLECULAR INSIGHTS INTO PROLYL AND LYSYL HYDROXYLATION OF FIBRILLAR COLLAGENS IN HEALTH AND DISEASE.CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 52. ISSUE 1. P. 74 -95 69 41% 0
3 KIVIRIKKO, KI , PIHLAJANIEMI, T , (1998) COLLAGEN HYDROXYLASES AND THE PROTEIN DISULFIDE ISOMERASE SUBUNIT OF PROLYL 4-HYDROXYLASES.ADVANCES IN ENZYMOLOGY, VOL 72. VOL. 72. ISSUE . P. 325 -+ 90 39% 187
4 MYLLYLA, R , WANG, CG , HEIKKINEN, J , JUFFER, A , LAMPELA, O , RISTELI, M , RUOTSALAINEN, H , SALO, A , SIPILA, L , (2007) EXPANDING THE LYSYL HYDROXYLASE TOOLBOX: NEW INSIGHTS INTO THE LOCALIZATION AND ACTIVITIES OF LYSYL HYDROXYLASE 3 (LH3).JOURNAL OF CELLULAR PHYSIOLOGY. VOL. 212. ISSUE 2. P. 323-329 34 81% 41
5 HYRY, M , LANTTO, J , MYLLYHARJU, J , (2009) MISSENSE MUTATIONS THAT CAUSE BRUCK SYNDROME AFFECT ENZYMATIC ACTIVITY, FOLDING, AND OLIGOMERIZATION OF LYSYL HYDROXYLASE 2.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 284. ISSUE 45. P. 30917 -30924 31 82% 12
6 YARNAUCHI, M , SRICHOLPECH, M , (2012) LYSINE POST-TRANSLATIONAL MODIFICATIONS OF COLLAGEN.LYSINE-BASED POST-TRANSLATIONAL MODIFICATION OF PROTEINS. VOL. 52. ISSUE . P. 113-133 44 52% 1
7 TAKALUOMA, K , LANTTO, J , MYLLYHARJU, J , (2007) LYSYL HYDROXYLASE 2 IS A SPECIFIC TELOPEPTIDE HYDROXYLASE, WHILE ALL THREE ISOENZYMES HYDROXYLATE COLLAGENOUS SEQUENCES.MATRIX BIOLOGY. VOL. 26. ISSUE 5. P. 396 -403 31 70% 23
8 SALO, AM , SIPILA, L , SORMUNEN, R , RUOTSALAINEN, H , VAINIO, S , MYLLYLA, R , (2006) THE LYSYL HYDROXYLASE ISOFORMS ARE WIDELY EXPRESSED DURING MOUSE EMBRYOGENESIS, BUT OBTAIN TISSUE- AND CELL-SPECIFIC PATTERNS IN THE ADULT.MATRIX BIOLOGY. VOL. 25. ISSUE 8. P. 475-483 29 74% 11
9 HEIKKINEN, J , RISTELI, M , LAMPELA, O , ALAVESA, P , KARPPINEN, M , JUFFER, AH , MYLLYLA, R , (2011) DIMERIZATION OF HUMAN LYSYL HYDROXYLASE 3 (LH3) IS MEDIATED BY THE AMINO ACIDS 541-547.MATRIX BIOLOGY. VOL. 30. ISSUE 1. P. 27 -33 26 70% 7
10 SRICHOLPECH, M , PERDIVARA, I , NAGAOKA, H , YOKOYAMA, M , TOMER, KB , YAMAUCHI, M , (2011) LYSYL HYDROXYLASE 3 GLUCOSYLATES GALACTOSYLHYDROXYLYSINE RESIDUES IN TYPE I COLLAGEN IN OSTEOBLAST CULTURE.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 286. ISSUE 11. P. 8846 -8856 32 53% 10

Classes with closest relation at Level 1


Rank Class id link
1 7695 PROTEIN DISULFIDE ISOMERASE//PROTEIN DISULPHIDE ISOMERASE//ERP29
2 27780 CUTICLIN//NEMATODE CUTICLE//CUT 1 LIKE PROTEINS
3 11104 LARP6//COLLAGEN GENES//ALPHA 2I COLLAGEN
4 31577 PROLINE 3 HYDROXYLASE//PROLINE 4 HYDROXYLASE//ALPHA KETOGLUTARATE DEPENDENT IRONII OXYGENASES
5 3041 OSTEOGENESIS IMPERFECTA//BONE EXTRACELLULAR MATRIX BRANCH//BRUCK SYNDROME
6 9510 TRIPLE HELIX//COLLAGEN LIKE PEPTIDE//FLUOROPROLINE
7 7639 EHLERS DANLOS SYNDROME//JOINT HYPERMOBILITY//HYPERMOBILITY
8 8944 TYPE V COLLAGEN//COLLAGEN XII//TYPE XI COLLAGEN
9 3879 PYRIDINOLINE//DEOXYPYRIDINOLINE//OSTEOCALCIN
10 24934 HSP47//HEAT SHOCK PROTEIN 47//UMB GREENEBAUM CANC

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