Class information for:
Level 1: ENDOTOXIN TOLERANCE//LPS TOLERANCE//IRAK M

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
16857 631 44.1 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
449 3       FAMILIAL MEDITERRANEAN FEVER//TOLL LIKE RECEPTORS//INFLAMMASOME 25887
543 2             TOLL LIKE RECEPTORS//INNATE IMMUNITY//CPG ODN 14712
16857 1                   ENDOTOXIN TOLERANCE//LPS TOLERANCE//IRAK M 631

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ENDOTOXIN TOLERANCE authKW 995388 10% 34% 60
2 LPS TOLERANCE authKW 290333 2% 50% 12
3 IRAK M authKW 126428 1% 29% 9
4 INVEST DERMATOL IMMUNODEFICIENCY address 96782 0% 100% 2
5 SEVERE SYSTEMIC INFLAMMATION authKW 96782 0% 100% 2
6 SERV P DIS address 72583 0% 50% 3
7 ENDOTOXIN PRETREATMENT authKW 64520 0% 67% 2
8 JOURNAL OF ENDOTOXIN RESEARCH journal 63972 4% 5% 27
9 ABDOMINAL SURGICAL OPERATION authKW 48391 0% 100% 1
10 AGCY SCI TECHNOL IMMUNOS address 48391 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 5881 46% 0% 292
2 Critical Care Medicine 2630 13% 0% 81
3 Hematology 1211 14% 0% 88
4 Infectious Diseases 460 9% 0% 55
5 Surgery 456 16% 0% 102
6 Cell Biology 434 15% 0% 95
7 Peripheral Vascular Diseases 386 8% 0% 50
8 Microbiology 243 10% 0% 60
9 Medicine, Research & Experimental 115 6% 0% 39
10 Biochemistry & Molecular Biology 72 13% 0% 85

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INVEST DERMATOL IMMUNODEFICIENCY 96782 0% 100% 2
2 SERV P DIS 72583 0% 50% 3
3 AGCY SCI TECHNOL IMMUNOS 48391 0% 100% 1
4 BIOL SCI INFLAMMAT BIOL IMMUNOBIOL 48391 0% 100% 1
5 BIOL SCI PATHOBIOL BIOMED SCI 48391 0% 100% 1
6 BRISTOL ROYAL INFIRMBHI 48391 0% 100% 1
7 CLEVELAND CITYWIDE PEDIAT INFECT DIS PROGRAM 48391 0% 100% 1
8 CLIN GRP SHOCK MULTI ORGAN FAILURE DFG 48391 0% 100% 1
9 CORILLON MED 48391 0% 100% 1
10 EA CYTOKINE INFLAMMAT 3806 48391 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF ENDOTOXIN RESEARCH 63972 4% 5% 27
2 SHOCK 21671 7% 1% 42
3 JOURNAL OF LEUKOCYTE BIOLOGY 5818 5% 0% 29
4 JOURNAL OF INFLAMMATION 5507 0% 4% 3
5 JOURNAL OF IMMUNOLOGY 3773 10% 0% 65
6 INNATE IMMUNITY 3397 1% 1% 6
7 PROGRESS IN CLINICAL AND BIOLOGICAL RESEARCH 2386 0% 2% 2
8 JOURNAL OF SURGICAL RESEARCH 1648 3% 0% 19
9 INFECTION AND IMMUNITY 1494 5% 0% 29
10 CRITICAL CARE MEDICINE 1173 3% 0% 17

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ENDOTOXIN TOLERANCE 995388 10% 34% 60 Search ENDOTOXIN+TOLERANCE Search ENDOTOXIN+TOLERANCE
2 LPS TOLERANCE 290333 2% 50% 12 Search LPS+TOLERANCE Search LPS+TOLERANCE
3 IRAK M 126428 1% 29% 9 Search IRAK+M Search IRAK+M
4 SEVERE SYSTEMIC INFLAMMATION 96782 0% 100% 2 Search SEVERE+SYSTEMIC+INFLAMMATION Search SEVERE+SYSTEMIC+INFLAMMATION
5 ENDOTOXIN PRETREATMENT 64520 0% 67% 2 Search ENDOTOXIN+PRETREATMENT Search ENDOTOXIN+PRETREATMENT
6 ABDOMINAL SURGICAL OPERATION 48391 0% 100% 1 Search ABDOMINAL+SURGICAL+OPERATION Search ABDOMINAL+SURGICAL+OPERATION
7 ALLOMRMUNE RESPONSE 48391 0% 100% 1 Search ALLOMRMUNE+RESPONSE Search ALLOMRMUNE+RESPONSE
8 ANTI IGM ANTIBODIES 48391 0% 100% 1 Search ANTI+IGM+ANTIBODIES Search ANTI+IGM+ANTIBODIES
9 ANTI TLR2 ANTIBODY 48391 0% 100% 1 Search ANTI+TLR2+ANTIBODY Search ANTI+TLR2+ANTIBODY
10 BRONCHIAL INSTILLATION 48391 0% 100% 1 Search BRONCHIAL+INSTILLATION Search BRONCHIAL+INSTILLATION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CROSS, AS , (2002) ENDOTOXIN TOLERANCE - CURRENT CONCEPTS IN HISTORICAL PERSPECTIVE.JOURNAL OF ENDOTOXIN RESEARCH. VOL. 8. ISSUE 2. P. 83 -98 81 71% 62
2 WEST, MA , HEAGY, W , (2002) ENDOTOXIN TOLERANCE: A REVIEW.CRITICAL CARE MEDICINE. VOL. 30. ISSUE 1. P. S64-S73 72 62% 245
3 LEHNER, MD , HARTUNG, T , (2002) ENDOTOXIN TOLERANCE - MECHANISMS AND BENEFICIAL EFFECTS IN BACTERIAL INFECTION.REVIEWS OF PHYSIOLOGY BIOCHEMISTRY AND PHARMACOLOGY, VOL 144. VOL. 144. ISSUE . P. 95 -141 107 51% 28
4 NAHID, MA , SATOH, M , CHAN, EKL , (2011) MICRORNA IN TLR SIGNALING AND ENDOTOXIN TOLERANCE.CELLULAR & MOLECULAR IMMUNOLOGY. VOL. 8. ISSUE 5. P. 388 -403 83 36% 101
5 FAN, HK , COOK, JA , (2004) MOLECULAR MECHANISMS OF ENDOTOXIN TOLERANCE.JOURNAL OF ENDOTOXIN RESEARCH. VOL. 10. ISSUE 2. P. 71-84 61 49% 265
6 CAVAILLON, JM , ADRIE, C , FITTING, C , ADIB-CONQUY, M , (2003) ENDOTOXIN TOLERANCE: IS THERE A CLINICAL RELEVANCE?.JOURNAL OF ENDOTOXIN RESEARCH. VOL. 9. ISSUE 2. P. 101 -107 40 67% 124
7 BISWAS, SK , LOPEZ-COLLAZO, E , (2009) ENDOTOXIN TOLERANCE: NEW MECHANISMS, MOLECULES AND CLINICAL SIGNIFICANCE.TRENDS IN IMMUNOLOGY. VOL. 30. ISSUE 10. P. 475 -487 35 32% 436
8 WEST, MA , KOONS, A , (2008) ENDOTOXIN TOLERANCE IN SEPSIS: CONCENTRATION-DEPENDENT AUGMENTATION OR INHIBITION OF LPS-STIMULATED MACROPHAGE TNF SECRETION BY LPS PRETREATMENT.JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE. VOL. 65. ISSUE 4. P. 893-898 24 77% 19
9 COLE, TS , ZHANG, M , STANDIFORD, TJ , NEWSTEAD, M , LUTHER, J , ZHANG, JJ , CHEN, CC , KAO, JY , (2012) IRAK-M MODULATES EXPRESSION OF IL-10 AND CELL SURFACE MARKERS CD80 AND MHC II AFTER BACTERIAL RE-STIMULATION OF TOLERIZED DENDRITIC CELLS.IMMUNOLOGY LETTERS. VOL. 144. ISSUE 1-2. P. 49-59 31 53% 10
10 COLLINS, PE , CARMODY, RJ , (2015) THE REGULATION OF ENDOTOXIN TOLERANCE AND ITS IMPACT ON MACROPHAGE ACTIVATION.CRITICAL REVIEWS IN IMMUNOLOGY. VOL. 35. ISSUE 4. P. 293 -323 57 27% 3

Classes with closest relation at Level 1


Rank Class id link
1 7878 IMMUNOPARALYSIS//SEPSIS//CECAL LIGATION AND PUNCTURE
2 13288 IRAK 4//TIR DOMAIN//IRAK
3 2866 CD14//MD 2//LIPOPOLYSACCHARIDE BINDING PROTEIN
4 27984 A TUMEFACIENS AND ECOLI//ANTIBODY RESPONSE TO POLYSACCHARIDE ANTIGENS//DETP IMMUNOL CELL BIOL
5 33294 METHYL PALMITATE//HEPATOCELLULAR NECROSIS FOCAL//LIVER ENDOTOXIN TOXICITY
6 34857 LIPOPOLYSACCHARIDE INDUCED TNF ALPHA FACTOR//LITAF//LPS INDUCED TNF ALPHA FACTOR
7 34706 BURSAL DISEASE VIRUS BDV//VIRUS VACCINE THERAPY//ACTA MICROBIOLOGICA HUNGARICA
8 27223 CONTROL INNATE IMMUN//INTEGRATED HOLIST IMMUNOL//ONO 4007
9 36082 FAILURE OF NEUTROPHIL MIGRATION//NEUTROPHIL MIGRATION FAILURE//NEUTROPHIL MIGRATION INHIBITION
10 25523 EXPT LUNG//LUNG INFLAMMAT INFECT//PULM CRIT CARE MED INFECT DIS

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