Class information for:
Level 1: HYDROXYPYRIDINONE//3 HYDROXY 4 PYRIDINONES//3 HYDROXYPYRIDIN 4 ONE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
16711 640 33.0 61%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
332 3       ERYTHROPOIETIN//ANEMIA//FERRITIN 37752
210 2             IRON OVERLOAD//HEPCIDIN//HEMOCHROMATOSIS 20783
16711 1                   HYDROXYPYRIDINONE//3 HYDROXY 4 PYRIDINONES//3 HYDROXYPYRIDIN 4 ONE 640

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HYDROXYPYRIDINONE authKW 1351141 7% 60% 47
2 3 HYDROXY 4 PYRIDINONES authKW 574501 3% 71% 17
3 3 HYDROXYPYRIDIN 4 ONE authKW 477102 2% 100% 10
4 IRON CHELATOR authKW 270649 8% 11% 53
5 HEXADENTATE authKW 238541 2% 50% 10
6 41H PYRIDINONES authKW 190841 1% 100% 4
7 HYDROXYPYRIDINONATE COMPLEXES authKW 190841 1% 100% 4
8 PFE3 VALUE authKW 190841 1% 100% 4
9 AL CHELATORS authKW 143131 0% 100% 3
10 OXIDATION MICHAEL ADDITION authKW 143131 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Inorganic & Nuclear 3523 27% 0% 171
2 Chemistry, Medicinal 904 12% 0% 75
3 Chemistry, Multidisciplinary 503 20% 0% 130
4 Crystallography 441 8% 0% 49
5 Chemistry, Organic 353 12% 0% 77
6 Pharmacology & Pharmacy 139 11% 0% 71
7 Biochemistry & Molecular Biology 59 13% 0% 81
8 Chemistry, Analytical 58 6% 0% 36
9 Hematology 23 3% 0% 17
10 Spectroscopy 6 2% 0% 10

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 REQUIMTE UCIBIO 56790 1% 24% 5
2 BIOCHEM NUTIENT 47710 0% 100% 1
3 CENT MANCHESTER NHS HOSP FDN TRUST 47710 0% 100% 1
4 CHIM COMPOSTI METALLORG 47710 0% 100% 1
5 CIQ UP QUIM BIOQUIM CIENCIASIBMC 47710 0% 100% 1
6 CNRSLG2AUMR 7378 47710 0% 100% 1
7 DIPARITMENTO CITOMORFOL 47710 0% 100% 1
8 DRUG CONTROL CENT 47710 0% 100% 1
9 FARM PROD STORAGE F H KEEPING 47710 0% 100% 1
10 GULHANE PHARMACOL 47710 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FINNISH CHEMICAL LETTERS 13784 1% 3% 9
2 JOURNAL OF INORGANIC BIOCHEMISTRY 8659 5% 1% 32
3 DALTON TRANSACTIONS 1478 4% 0% 24
4 JOURNAL OF MEDICINAL CHEMISTRY 949 3% 0% 21
5 INORGANICA CHIMICA ACTA 790 3% 0% 17
6 TRANSITION METAL CHEMISTRY 756 1% 0% 9
7 METALLOMICS 740 1% 0% 4
8 JOURNAL OF PHARMACY AND PHARMACOLOGY 704 2% 0% 11
9 POLYHEDRON 634 2% 0% 15
10 ANNALI DI CHIMICA 606 1% 0% 5

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HYDROXYPYRIDINONE 1351141 7% 60% 47 Search HYDROXYPYRIDINONE Search HYDROXYPYRIDINONE
2 3 HYDROXY 4 PYRIDINONES 574501 3% 71% 17 Search 3+HYDROXY+4+PYRIDINONES Search 3+HYDROXY+4+PYRIDINONES
3 3 HYDROXYPYRIDIN 4 ONE 477102 2% 100% 10 Search 3+HYDROXYPYRIDIN+4+ONE Search 3+HYDROXYPYRIDIN+4+ONE
4 IRON CHELATOR 270649 8% 11% 53 Search IRON+CHELATOR Search IRON+CHELATOR
5 HEXADENTATE 238541 2% 50% 10 Search HEXADENTATE Search HEXADENTATE
6 41H PYRIDINONES 190841 1% 100% 4 Search 41H+PYRIDINONES Search 41H+PYRIDINONES
7 HYDROXYPYRIDINONATE COMPLEXES 190841 1% 100% 4 Search HYDROXYPYRIDINONATE+COMPLEXES Search HYDROXYPYRIDINONATE+COMPLEXES
8 PFE3 VALUE 190841 1% 100% 4 Search PFE3+VALUE Search PFE3+VALUE
9 AL CHELATORS 143131 0% 100% 3 Search AL+CHELATORS Search AL+CHELATORS
10 OXIDATION MICHAEL ADDITION 143131 0% 100% 3 Search OXIDATION+MICHAEL+ADDITION Search OXIDATION+MICHAEL+ADDITION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BURGESS, J , RANGEL, M , (2008) HYDROXYPYRANONES, HYDROXYPYRIDINONES, AND THEIR COMPLEXES.ADVANCES IN INORGANIC CHEMISTRY, VOL 60. VOL. 60. ISSUE . P. 167 -243 135 44% 8
2 SANTOS, MA , MARQUES, SM , CHAVES, S , (2012) HYDROXYPYRIDINONES AS "PRIVILEGED" CHELATING STRUCTURES FOR THE DESIGN OF MEDICINAL DRUGS.COORDINATION CHEMISTRY REVIEWS. VOL. 256. ISSUE 1-2. P. 240 -259 60 33% 44
3 THOMPSON, KH , BARTA, CA , ORVIG, C , (2006) METAL COMPLEXES OF MALTOL AND CLOSE ANALOGUES IN MEDICINAL INORGANIC CHEMISTRY.CHEMICAL SOCIETY REVIEWS. VOL. 35. ISSUE 6. P. 545-556 59 40% 72
4 SANTOS, MA , CHAVES, S , (2015) 3-HYDROXYPYRIDINONE DERIVATIVES AS METAL-SEQUESTERING AGENTS FOR THERAPEUTIC USE.FUTURE MEDICINAL CHEMISTRY. VOL. 7. ISSUE 3. P. 383 -410 58 35% 2
5 HIDER, RC , LIU, ZD , (2003) EMERGING UNDERSTANDING OF THE ADVANTAGE OF SMALL MOLECULES SUCH AS HYDROXYPYRIDINONES IN THE TREATMENT OF IRON OVERLOAD.CURRENT MEDICINAL CHEMISTRY. VOL. 10. ISSUE 12. P. 1051 -1064 31 76% 43
6 CHAVES, S , SANTOS, MA , ESTEVES, MA , (2012) HYDROXYPYRI(MI)DINE-BASED CHELATORS AS ANTIDOTES OF TOXICITY DUE TO ALUMINUM AND ACTINIDES.CURRENT MEDICINAL CHEMISTRY. VOL. 19. ISSUE 17. P. 2773 -2793 46 38% 4
7 ZHOU, T , HIDER, RC , KONG, XL , (2015) MODE OF IRON(III) CHELATION BY HEXADENTATE HYDROXYPYRIDINONES.CHEMICAL COMMUNICATIONS. VOL. 51. ISSUE 26. P. 5614 -5617 18 90% 1
8 LACHOWICZ, JI , NURCHI, VM , CRISPONI, G , JARAQUEMADA-PELAEZ, MG , ARCA, M , PINTUS, A , SANTOS, MA , QUINTANOVA, C , GANO, L , SZEWCZUK, Z , ET AL (2016) HYDROXYPYRIDINONES WITH ENHANCED IRON CHELATING PROPERTIES. SYNTHESIS, CHARACTERIZATION AND IN VIVO TESTS OF 5-HYDROXY-2-(HYDROXYMETHYL) PYRIDINE-4(1H)-ONE.DALTON TRANSACTIONS. VOL. 45. ISSUE 15. P. 6517 -6528 21 55% 1
9 NURCHI, VM , CRISPONI, G , LACHOWICZ, JI , MEDICI, S , PEAN, M , ZORODDU, MA , (2016) CHEMICAL FEATURES OF IN USE AND IN PROGRESS CHELATORS FOR IRON OVERLOAD.JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. VOL. 38. ISSUE . P. 10 -18 25 44% 1
10 LIU, ZD , HIDER, RC , (2002) DESIGN OF IRON CHELATORS WITH THERAPEUTIC APPLICATION.COORDINATION CHEMISTRY REVIEWS. VOL. 232. ISSUE 1-2. P. 151 -171 36 38% 168

Classes with closest relation at Level 1


Rank Class id link
1 27518 CHIMIOSENSIBIL PALUDISME//MULTIDENTATE AMINOTHIOLS//MEROZOITE RELEASE
2 928 IRON OVERLOAD//DEFERASIROX//THALASSEMIA
3 5568 SIDEROPHORE//ENTEROBACTIN//AMPHIPHILIC SIDEROPHORES
4 37087 4 2 1 ETHYLAMINO 2 METHYLPROPYLPHENYL 3 4 METHYPHENYL 1 PHENYLPYRAZOLE//MIXED LIGAND IRONIII COMPLEX//N N BIS4 METHOXY BENZYLIDENE 1 4 BIS3 AMINOPROPYLPIPERAZINE
5 12918 IRON METAB CHELAT PROGRAM//PYRIDOXAL ISONICOTINOYL HYDRAZONE//MOL PHARMACOL PATHOL PROGRAM
6 33096 CHRONOVOLTAMMETRY//14 MEMBERED RINGS//4 CHLORO AND 4 AMINO PICOLINIC ACID N OXIDE
7 15430 STATE COORDINAT CHEM CHINA//MOE LIFE SCI//AL 30
8 25259 UNIDADE RIO DE JANEIRO//EGYPTIAN ORG BIOL PROD VACCINES//POINT BY POINT ANALYSIS
9 7357 TYROSINASE INHIBITOR//MUSHROOM TYROSINASE//TYROSINASE
10 22972 ANTIANEMIC DRUGS//IRON PROTEIN SUCCINYLATE//MALTOFER R

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