Class information for:
Level 1: MATRIPTASE//CORIN//HEPSIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15913 684 42.0 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
427 3       JOURNAL OF THE INSTITUTE OF BREWING//KERATINASE//CYSTATIN 27946
1549 2             CYCLOTIDES//BOWMAN BIRK INHIBITOR//TRYPSIN INHIBITOR 7414
15913 1                   MATRIPTASE//CORIN//HEPSIN 684

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MATRIPTASE authKW 2928867 12% 81% 81
2 CORIN authKW 1157075 5% 72% 36
3 HEPSIN authKW 1153064 5% 70% 37
4 HAI 1 authKW 1033353 4% 93% 25
5 TYPE II TRANSMEMBRANE SERINE PROTEASE authKW 1005904 4% 87% 26
6 TMPRSS4 authKW 811651 3% 91% 20
7 HEPATOCYTE GROWTH FACTOR ACTIVATOR INHIBITOR 1 authKW 535692 2% 100% 12
8 HAI 2 authKW 405826 1% 91% 10
9 PROSTASIN authKW 361572 3% 45% 18
10 PROTEASES TISSUE REMODELING UNIT address 330782 2% 44% 17

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 1394 39% 0% 267
2 Oncology 1194 23% 0% 157
3 Cell Biology 866 20% 0% 134
4 Pathology 170 5% 0% 35
5 Chemistry, Medicinal 139 5% 0% 34
6 Biophysics 104 6% 0% 38
7 Urology & Nephrology 75 4% 0% 26
8 Physiology 71 5% 0% 31
9 Peripheral Vascular Diseases 60 4% 0% 24
10 Developmental Biology 32 2% 0% 12

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROTEASES TISSUE REMODELING UNIT 330782 2% 44% 17
2 PROTEASES TISSUE REMODELING SECT 301697 2% 48% 14
3 SECT ONCOPATHOL REGENERAT BIOL 234545 2% 31% 17
4 ENZYME CHEMSAKYO KU 229581 1% 86% 6
5 LOMBARDI CANC COMPREHENS 133923 0% 100% 3
6 ORAL PHARYNGEAL CANC BRANCH 104296 5% 7% 35
7 KIADB IND AREA 39 40 89282 0% 100% 2
8 LAMBARDI COMPREHENS CANC 89282 0% 100% 2
9 MOL CARDIOL NEPHROL HYPERTENS 89282 0% 100% 2
10 CYRUS TANG HEMATOL 77468 3% 8% 21

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUMAN CELL 5833 1% 3% 5
2 PROSTATE 1396 2% 0% 12
3 JOURNAL OF BIOLOGICAL CHEMISTRY 1206 10% 0% 66
4 BIOLOGICAL CHEMISTRY 1116 1% 0% 9
5 FRONTIERS IN BIOSCIENCE-LANDMARK 997 1% 0% 9
6 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 876 2% 0% 12
7 AMERICAN JOURNAL OF PATHOLOGY 671 2% 0% 14
8 CANCER SCIENCE 609 1% 0% 7
9 JACC-HEART FAILURE 597 0% 1% 2
10 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 581 1% 0% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MATRIPTASE 2928867 12% 81% 81 Search MATRIPTASE Search MATRIPTASE
2 CORIN 1157075 5% 72% 36 Search CORIN Search CORIN
3 HEPSIN 1153064 5% 70% 37 Search HEPSIN Search HEPSIN
4 HAI 1 1033353 4% 93% 25 Search HAI+1 Search HAI+1
5 TYPE II TRANSMEMBRANE SERINE PROTEASE 1005904 4% 87% 26 Search TYPE+II+TRANSMEMBRANE+SERINE+PROTEASE Search TYPE+II+TRANSMEMBRANE+SERINE+PROTEASE
6 TMPRSS4 811651 3% 91% 20 Search TMPRSS4 Search TMPRSS4
7 HEPATOCYTE GROWTH FACTOR ACTIVATOR INHIBITOR 1 535692 2% 100% 12 Search HEPATOCYTE+GROWTH+FACTOR+ACTIVATOR+INHIBITOR+1 Search HEPATOCYTE+GROWTH+FACTOR+ACTIVATOR+INHIBITOR+1
8 HAI 2 405826 1% 91% 10 Search HAI+2 Search HAI+2
9 PROSTASIN 361572 3% 45% 18 Search PROSTASIN Search PROSTASIN
10 TTSP 312487 1% 100% 7 Search TTSP Search TTSP

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ANTALIS, TM , BUGGE, TH , WU, QY , (2011) MEMBRANE-ANCHORED SERINE PROTEASES IN HEALTH AND DISEASE.PROTEASES IN HEALTH AND DISEASE. VOL. 99. ISSUE . P. 1 -50 165 62% 20
2 MURRAY, AS , VARELA, FA , LIST, K , (2016) TYPE II TRANSMEMBRANE SERINE PROTEASES AS POTENTIAL TARGETS FOR CANCER THERAPY.BIOLOGICAL CHEMISTRY. VOL. 397. ISSUE 9. P. 815 -826 101 86% 0
3 ANTALIS, TM , BUZZA, MS , HODGE, KM , HOOPER, JD , NETZEL-ARNETT, S , (2010) THE CUTTING EDGE: MEMBRANE-ANCHORED SERINE PROTEASE ACTIVITIES IN THE PERICELLULAR MICROENVIRONMENT.BIOCHEMICAL JOURNAL. VOL. 428. ISSUE . P. 325-346 128 56% 39
4 SZABO, R , BUGGE, TH , (2008) TYPE II TRANSMEMBRANE SERINE PROTEASES IN DEVELOPMENT AND DISEASE.INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. VOL. 40. ISSUE 6-7. P. 1297-1316 106 66% 84
5 LIST, K , (2009) MATRIPTASE: A CULPRIT IN CANCER?.FUTURE ONCOLOGY. VOL. 5. ISSUE 1. P. 97-104 56 93% 33
6 WEBB, SL , SANDERS, AJ , MASON, MD , JIANG, WG , (2011) TYPE II TRANSMEMBRANE SERINE PROTEASE (TTSP) DEREGULATION IN CANCER.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 16. ISSUE . P. 539 -552 75 65% 18
7 FRIIS, S , SALES, KU , SCHAFER, JM , VOGEL, LK , KATAOKA, H , BUGGE, TH , (2014) THE PROTEASE INHIBITOR HAI-2, BUT NOT HAI-1, REGULATES MATRIPTASE ACTIVATION AND SHEDDING THROUGH PROSTASIN.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 289. ISSUE 32. P. 22319 -22332 47 87% 5
8 BERGUM, C , LIST, K , (2010) LOSS OF THE MATRIPTASE INHIBITOR HAI-2 DURING PROSTATE CANCER PROGRESSION.PROSTATE. VOL. 70. ISSUE 13. P. 1422-1428 40 95% 11
9 CHU, LL , XU, Y , YANG, JR , HU, YA , CHANG, HH , LAI, HY , TSENG, CC , WANG, HY , JOHNSON, MD , WANG, JK , ET AL (2014) HUMAN CANCER CELLS RETAIN MODEST LEVELS OF ENZYMATICALLY ACTIVE MATRIPTASE ONLY IN EXTRACELLULAR MILIEU FOLLOWING INDUCTION OF ZYMOGEN ACTIVATION.PLOS ONE. VOL. 9. ISSUE 3. P. - 40 87% 2
10 SZABO, R , KOSA, P , LIST, K , BUGGE, TH , (2009) LOSS OF MATRIPTASE SUPPRESSION UNDERLIES SPINT1 MUTATION-ASSOCIATED ICHTHYOSIS AND POSTNATAL LETHALITY.AMERICAN JOURNAL OF PATHOLOGY. VOL. 174. ISSUE 6. P. 2015-2022 40 93% 23

Classes with closest relation at Level 1


Rank Class id link
1 29611 ENTEROPEPTIDASE//DUODENASE//ENTEROKINASE
2 25646 DEV MODEL//NEW YORK EXCELLENCE INFLUENZA SURVEILLA//MINI PLASMIN
3 23172 RON//MACROPHAGE STIMULATING PROTEIN//RON RECEPTOR
4 10262 NETHERTON SYNDROME//KALLIKREIN//KALLIKREIN RELATED PEPTIDASES
5 303 HEPATOCYTE GROWTH FACTOR//C MET//HGF
6 34709 CDCP1//CUB DOMAIN CONTAINING PROTEIN 1//TRASK
7 23215 DEGRADOMICS//LIFE SCI 4 401//N TERMINOMICS
8 2208 ENAC//EPITHELIAL SODIUM CHANNEL//LIDDLES SYNDROME
9 16343 CYCLOTIDES//KALATA B1//CIRCULAR PROTEINS
10 30859 GRHL2//GRAINYHEAD//LATE SV40 FACTOR

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