Class information for:
Level 1: NICORANDIL//KRN2391//CAS 65141 46 0

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15756 693 27.5 71%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
11 3       ATRIAL FIBRILLATION//CARDIAC & CARDIOVASCULAR SYSTEM//CATHETER ABLATION 130936
1189 2             NICORANDIL//ISCHEMIC PRECONDITIONING//K ATP CHANNEL 9282
15756 1                   NICORANDIL//KRN2391//CAS 65141 46 0 693

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NICORANDIL authKW 6554991 39% 55% 270
2 KRN2391 authKW 769056 3% 73% 24
3 CAS 65141 46 0 authKW 132184 0% 100% 3
4 K ATP CHANNEL ACTIVATION authKW 132184 0% 100% 3
5 POTASSIUM CHANNEL OPENERS authKW 96242 4% 9% 25
6 CYCLIC GMP HYPERPOLARIZATION authKW 88122 0% 100% 2
7 KI3315 authKW 88122 0% 100% 2
8 N K HYBRID authKW 88122 0% 100% 2
9 NICORANDIL CLINICAL STUDIES authKW 88122 0% 100% 2
10 ORAL NICORANDIL AND RATS authKW 88122 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cardiac & Cardiovascular System 6913 39% 0% 273
2 Pharmacology & Pharmacy 6026 54% 0% 375
3 Dance 54 0% 0% 1
4 Dermatology 51 3% 0% 18
5 Peripheral Vascular Diseases 41 3% 0% 21
6 Anesthesiology 23 1% 0% 10
7 Chemistry, Medicinal 18 2% 0% 16
8 Physiology 11 2% 0% 17
9 Toxicology 8 2% 0% 13
10 Surgery 8 4% 0% 30

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BEIJING CHAO YAN HOSP 44061 0% 100% 1
2 CARDIAC SURG CARDIOVASC PHARMACOL 44061 0% 100% 1
3 CARDIOVASC MED MED BIOREGULAT 44061 0% 100% 1
4 CONSULTAT ONCOL STOMATOL MED 44061 0% 100% 1
5 EAR NOSE THROAT REG HEAD NECK CANC 44061 0% 100% 1
6 INSERMGRP ELE OPHYSIOL MOL 44061 0% 100% 1
7 INT ELDERLY PROBLEMS ZDOROVOE DOLGOLETIE 44061 0% 100% 1
8 INTEGRAT HUMAN CARDIOVASC PHYSIOL FUNCT GE 44061 0% 100% 1
9 KTEDA INT CARDIOVASC HOSP 44061 0% 100% 1
10 PATHOLINFLAMMAT UNIT 44061 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 33221 13% 1% 91
2 CARDIOVASCULAR DRUGS AND THERAPY 15350 4% 1% 26
3 JAPANESE JOURNAL OF PHARMACOLOGY 5767 3% 1% 24
4 ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE 4369 2% 1% 15
5 GENERAL PHARMACOLOGY-THE VASCULAR SYSTEM 3826 2% 1% 15
6 CIRCULATION JOURNAL 2429 2% 0% 16
7 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 1839 2% 0% 16
8 PHARMACOLOGY 1607 2% 0% 11
9 JAPANESE HEART JOURNAL 1318 1% 0% 8
10 BRITISH JOURNAL OF PHARMACOLOGY 1171 3% 0% 22

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NICORANDIL 6554991 39% 55% 270 Search NICORANDIL Search NICORANDIL
2 KRN2391 769056 3% 73% 24 Search KRN2391 Search KRN2391
3 CAS 65141 46 0 132184 0% 100% 3 Search CAS+65141+46+0 Search CAS+65141+46+0
4 K ATP CHANNEL ACTIVATION 132184 0% 100% 3 Search K+ATP+CHANNEL+ACTIVATION Search K+ATP+CHANNEL+ACTIVATION
5 POTASSIUM CHANNEL OPENERS 96242 4% 9% 25 Search POTASSIUM+CHANNEL+OPENERS Search POTASSIUM+CHANNEL+OPENERS
6 CYCLIC GMP HYPERPOLARIZATION 88122 0% 100% 2 Search CYCLIC+GMP+HYPERPOLARIZATION Search CYCLIC+GMP+HYPERPOLARIZATION
7 KI3315 88122 0% 100% 2 Search KI3315 Search KI3315
8 N K HYBRID 88122 0% 100% 2 Search N+K+HYBRID Search N+K+HYBRID
9 NICORANDIL CLINICAL STUDIES 88122 0% 100% 2 Search NICORANDIL+CLINICAL+STUDIES Search NICORANDIL+CLINICAL+STUDIES
10 ORAL NICORANDIL AND RATS 88122 0% 100% 2 Search ORAL+NICORANDIL+AND+RATS Search ORAL+NICORANDIL+AND+RATS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 PISANO, U , DEOSARAN, J , LESLIE, SJ , RUSHWORTH, GF , STEWART, D , FORD, I , WATSON, AJM , (2016) NICORANDIL, GASTROINTESTINAL ADVERSE DRUG REACTIONS AND ULCERATIONS: A SYSTEMATIC REVIEW.ADVANCES IN THERAPY. VOL. 33. ISSUE 3. P. 320 -344 60 78% 1
2 SIMPSON, D , WELLINGTON, K , (2004) NICORANDIL - A REVIEW OF ITS USE IN THE MANAGEMENT OF STABLE ANGINA PECTORIS, INCLUDING HIGH-RISK PATIENTS.DRUGS. VOL. 64. ISSUE 17. P. 1941-1955 57 77% 27
3 HORINAKA, S , (2011) USE OF NICORANDIL IN CARDIOVASCULAR DISEASE AND ITS OPTIMIZATION.DRUGS. VOL. 71. ISSUE 9. P. 1105 -1119 61 57% 21
4 MARKHAM, A , PLOSKER, GL , GOA, KL , (2000) NICORANDIL - AN UPDATED REVIEW OF ITS USE IN ISCHAEMIC HEART DISEASE WITH EMPHASIS ON ITS CARDIOPROTECTIVE EFFECTS.DRUGS. VOL. 60. ISSUE 4. P. 955 -974 45 78% 64
5 LEE, MTG , LIN, HY , LEE, SH , LEE, SH , CHANG, SS , CHEN, SC , LEE, CC , (2015) RISK OF SKIN ULCERATIONS ASSOCIATED WITH ORAL NICORANDIL THERAPY: A POPULATION-BASED STUDY.BRITISH JOURNAL OF DERMATOLOGY. VOL. 173. ISSUE 2. P. 498 -509 27 79% 3
6 SAKAI, K , (1989) NICORANDIL - ANIMAL PHARMACOLOGY.AMERICAN JOURNAL OF CARDIOLOGY. VOL. 63. ISSUE 21. P. J2-J10 59 79% 23
7 FRAMPTON, J , BUCKLEY, MM , FITTON, A , (1992) NICORANDIL - A REVIEW OF ITS PHARMACOLOGY AND THERAPEUTIC EFFICACY IN ANGINA-PECTORIS.DRUGS. VOL. 44. ISSUE 4. P. 625-655 54 68% 70
8 ZHAO, FJ , CHAUGAI, S , CHEN, P , WANG, Y , WANG, DW , (2014) EFFECT OF NICORANDIL IN PATIENTS WITH HEART FAILURE: A SYSTEMATIC REVIEW AND META-ANALYSIS.CARDIOVASCULAR THERAPEUTICS. VOL. 32. ISSUE 6. P. 283 -296 28 68% 5
9 GOLDSCHMIDT, M , LANDZBERG, BR , FRISHMAN, WH , (1996) NICORANDIL A POTASSIUM CHANNEL OPENING DRUG FOR TREATMENT OF ISCHEMIC HEART DISEASE.JOURNAL OF CLINICAL PHARMACOLOGY. VOL. 36. ISSUE 7. P. 559-572 45 68% 19
10 LEE, CC , CHANG, SS , LEE, SH , CHEN, YS , HSU, WT , LEE, MTG , (2015) USE OF NICORANDIL IS ASSOCIATED WITH INCREASED RISK FOR GASTROINTESTINAL ULCERATION AND PERFORATION- A NATIONALLY REPRESENTATIVE POPULATION- BASED STUDY.SCIENTIFIC REPORTS. VOL. 5. ISSUE . P. - 26 65% 1

Classes with closest relation at Level 1


Rank Class id link
1 761 ATP SENSITIVE K CHANNEL//K ATP CHANNEL//ATP SENSITIVE POTASSIUM CHANNEL
2 35384 CD 832//PRANIDIPINE//KT 362
3 24830 NIPRADILOL//BOPINDOLOL//BOPINDOLOL METABOLITES
4 11790 INTRACELLULAR ION CHANNELS//DIAZOXIDE//5 HYDROXYDECANOATE
5 1726 NITRATE TOLERANCE//NITROGLYCERIN//ORGANIC NITRATES
6 1374 ISCHEMIC PRECONDITIONING//PRECONDITIONING//ISCHAEMIC PRECONDITIONING
7 32277 I 125 IOMAZENIL//7R TRANS BENZOAPYRENE 7 8 DIHYDRODIOL//AFFILIATED KANGNING HOSP
8 26242 VASOMOTION//RHYTHMIC CONTRACTIONS//VASOMOTION PATTERNS
9 23054 TIROPRAMIDE//ILEAL MUSCLE//INTESTINE SMOOTH
10 34223 BOVINE BRONCHI//8 BRCGMP 8 BROMOGUANOSINE 3 5 CYCLIC MONOPHOSPHATE//ACROLEIN UPTAKE

Go to start page