Class information for:
Level 1: IMMOBILIZED TRYPSIN//PROTEIN DIGESTION//IMMOBILIZED ENZYME REACTOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15699 697 34.6 85%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
239 3       LIPASE//JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC//BIOCATALYSIS 47598
647 2             LIPASE//PENICILLIN ACYLASE//IMMOBILIZATION 13621
15699 1                   IMMOBILIZED TRYPSIN//PROTEIN DIGESTION//IMMOBILIZED ENZYME REACTOR 697

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IMMOBILIZED TRYPSIN authKW 573470 3% 55% 24
2 PROTEIN DIGESTION authKW 243945 4% 19% 29
3 IMMOBILIZED ENZYME REACTOR authKW 201387 3% 23% 20
4 IMER authKW 195141 1% 64% 7
5 ON LINE DIGESTION authKW 190460 1% 43% 10
6 IMMOBILIZED TRYPSIN REACTORS authKW 175233 1% 100% 4
7 IMMOBILIZED ENZYME MICROREACTOR authKW 156456 1% 71% 5
8 MICROSPACE CHEM address 154271 1% 39% 9
9 CHEMICAL PROTEOLYSIS authKW 131425 0% 100% 3
10 HEXANOL OXIDATION authKW 131425 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Analytical 9566 50% 0% 348
2 Biochemical Research Methods 9132 38% 0% 266
3 Spectroscopy 334 7% 0% 46
4 Biotechnology & Applied Microbiology 238 9% 0% 64
5 Chemistry, Multidisciplinary 136 12% 0% 83
6 Engineering, Chemical 108 7% 0% 46
7 Biochemistry & Molecular Biology 92 14% 0% 98
8 Nanoscience & Nanotechnology 67 4% 0% 30
9 Engineering, Environmental 58 3% 0% 20
10 Materials Science, Biomaterials 45 2% 0% 11

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MICROSPACE CHEM 154271 1% 39% 9
2 NEUROBIOL CELLULAR ERS 58410 0% 67% 2
3 BIOMEA BIOL MOLLUSQUES MARINS ECOSYST ASSOC 43808 0% 100% 1
4 BIOMED ANALYS 43808 0% 100% 1
5 BIONANOCHIPS DIAGNOST TRANSLAT MED 43808 0% 100% 1
6 CANADA CHAIR PROTEOM SYST BIOL 43808 0% 100% 1
7 CHEM REACTOR ENGN MICRO FLOW CHEM PROCESS 43808 0% 100% 1
8 CHROMAT RA 43808 0% 100% 1
9 CHROMATOG RS 43808 0% 100% 1
10 CHROMATOGRPH RA 43808 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROTEOMICS 7807 5% 1% 32
2 ANALYTICAL CHEMISTRY 7775 11% 0% 80
3 JOURNAL OF PROTEOME RESEARCH 7321 5% 1% 32
4 JOURNAL OF CHROMATOGRAPHY A 4521 8% 0% 53
5 JOURNAL OF FLOW CHEMISTRY 2458 0% 2% 3
6 RAPID COMMUNICATIONS IN MASS SPECTROMETRY 2134 3% 0% 21
7 LAB ON A CHIP 1642 2% 0% 14
8 JOURNAL OF SEPARATION SCIENCE 1616 2% 0% 15
9 ELECTROPHORESIS 1476 3% 0% 20
10 JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY 1339 2% 0% 12

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 IMMOBILIZED TRYPSIN 573470 3% 55% 24 Search IMMOBILIZED+TRYPSIN Search IMMOBILIZED+TRYPSIN
2 PROTEIN DIGESTION 243945 4% 19% 29 Search PROTEIN+DIGESTION Search PROTEIN+DIGESTION
3 IMMOBILIZED ENZYME REACTOR 201387 3% 23% 20 Search IMMOBILIZED+ENZYME+REACTOR Search IMMOBILIZED+ENZYME+REACTOR
4 IMER 195141 1% 64% 7 Search IMER Search IMER
5 ON LINE DIGESTION 190460 1% 43% 10 Search ON+LINE+DIGESTION Search ON+LINE+DIGESTION
6 IMMOBILIZED TRYPSIN REACTORS 175233 1% 100% 4 Search IMMOBILIZED+TRYPSIN+REACTORS Search IMMOBILIZED+TRYPSIN+REACTORS
7 IMMOBILIZED ENZYME MICROREACTOR 156456 1% 71% 5 Search IMMOBILIZED+ENZYME+MICROREACTOR Search IMMOBILIZED+ENZYME+MICROREACTOR
8 CHEMICAL PROTEOLYSIS 131425 0% 100% 3 Search CHEMICAL+PROTEOLYSIS Search CHEMICAL+PROTEOLYSIS
9 HEXANOL OXIDATION 131425 0% 100% 3 Search HEXANOL+OXIDATION Search HEXANOL+OXIDATION
10 ENZYMATIC MICROREACTOR 131419 1% 50% 6 Search ENZYMATIC+MICROREACTOR Search ENZYMATIC+MICROREACTOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 SAFDAR, M , SPROSS, J , JANIS, J , (2014) MICROSCALE IMMOBILIZED ENZYME REACTORS IN PROTEOMICS: LATEST DEVELOPMENTS.JOURNAL OF CHROMATOGRAPHY A. VOL. 1324. ISSUE . P. 1 -10 56 50% 23
2 SWITZAR, L , GIERA, M , NIESSEN, WMA , (2013) PROTEIN DIGESTION: AN OVERVIEW OF THE AVAILABLE TECHNIQUES AND RECENT DEVELOPMENTS.JOURNAL OF PROTEOME RESEARCH. VOL. 12. ISSUE 3. P. 1067-1077 54 45% 61
3 MA, JF , ZHANG, LH , LIANG, Z , SHAN, YC , ZHANG, YK , (2011) IMMOBILIZED ENZYME REACTORS IN PROTEOMICS.TRAC-TRENDS IN ANALYTICAL CHEMISTRY. VOL. 30. ISSUE 5. P. 691 -702 40 73% 44
4 CMELIK, R , BOBALOVA, J , (2016) METHODS OF PROTEIN DIGESTION UTILIZABLE IN PROTEOMIC ANALYSIS.CHEMICKE LISTY. VOL. 110. ISSUE 3. P. 174 -178 40 70% 0
5 MA, JF , ZHANG, LH , LIANG, Z , ZHANG, WB , ZHANG, YK , (2009) RECENT ADVANCES IN IMMOBILIZED ENZYMATIC REACTORS AND THEIR APPLICATIONS IN PROTEOME ANALYSIS.ANALYTICA CHIMICA ACTA. VOL. 632. ISSUE 1. P. 1-8 44 61% 67
6 YAMAGUCHI, H , MIYAZAKI, M , (2013) ENZYME-IMMOBILIZED REACTORS FOR RAPID AND EFFICIENT SAMPLE PREPARATION IN MS-BASED PROTEOMIC STUDIES.PROTEOMICS. VOL. 13. ISSUE 3-4. P. 457-466 40 54% 22
7 LIU, S , BAO, HM , ZHANG, LY , CHEN, G , (2013) EFFICIENT PROTEOLYSIS STRATEGIES BASED ON MICROCHIP BIOREACTORS.JOURNAL OF PROTEOMICS. VOL. 82. ISSUE . P. 1-13 32 73% 5
8 LIN, S , YUN, D , QI, DW , DENG, CH , LI, Y , ZHANG, XM , (2008) NOVEL MICROWAVE-ASSISTED DIGESTION BY TRYPSIN-IMMOBILIZED MAGNETIC NANOPARTICLES FOR PROTEOMIC ANALYSIS.JOURNAL OF PROTEOME RESEARCH. VOL. 7. ISSUE 3. P. 1297-1307 31 74% 52
9 GHAFOURIFAR, G , FLEITZ, A , WALDRON, KC , (2013) DEVELOPMENT OF GLUTARALDEHYDE-CROSSLINKED CHYMOTRYPSIN AND AN IN SITU IMMOBILIZED ENZYME MICROREACTOR WITH PEPTIDE MAPPING BY CAPILLARY ELECTROPHORESIS.ELECTROPHORESIS. VOL. 34. ISSUE 12. P. 1804-1811 31 66% 12
10 MONZO, A , SPERLING, E , GUTTMAN, A , (2009) PROTEOLYTIC ENZYME-IMMOBILIZATION TECHNIQUES FOR MS-BASED PROTEIN ANALYSIS.TRAC-TRENDS IN ANALYTICAL CHEMISTRY. VOL. 28. ISSUE 7. P. 854 -864 32 65% 43

Classes with closest relation at Level 1


Rank Class id link
1 23697 ELECTROPHORETICALLY MEDIATED MICROANALYSIS//EMMA//ELECTROINJECTION ANALYSIS
2 14121 HYBRID NANOFLOWER//MESOSTRUCTURED CELLULAR FOAMS//ENZYME IMMOBILIZATION
3 6883 PREFRACTIONATION//FASP//SDS REMOVAL
4 5783 SHEATHLESS INTERFACE//CE MS//CAPILLARY ELECTROPHORESIS MASS SPECTROMETRY
5 1024 CAPILLARY ELECTROCHROMATOGRAPHY//ELECTROCHROMATOGRAPHY//MONOLITHIC COLUMN
6 24940 CROSS LINKED ENZYME AGGREGATES//CROSS LINKED ENZYME AGGREGATES CLEAS//FERMENTAT ENGN HEBEI
7 8239 QUANTITATIVE PROTEOMICS//STABLE ISOTOPE LABELING//ISOBARIC TAG
8 9567 TARGETED PROTEOMICS//SELECTED REACTION MONITORING//MULTIPLE REACTION MONITORING
9 2184 MICROCHIP ELECTROPHORESIS//MICROCHIP//MICROFLUIDIC CHIP
10 3166 FLOW CHEMISTRY//MICROREACTORS//MICROREACTOR

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