Class information for:
Level 1: GPR40//GPR120//GPR119

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15285 721 43.3 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
176 3       DIABETES CARE//ENDOCRINOLOGY & METABOLISM//TYPE 2 DIABETES 58057
1167 2             GLUCAGON LIKE PEPTIDE 1//GLP 1//INCRETIN 9383
15285 1                   GPR40//GPR120//GPR119 721

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GPR40 authKW 3849202 14% 87% 104
2 GPR120 authKW 1937940 8% 80% 57
3 GPR119 authKW 1473035 6% 87% 40
4 GPR43 authKW 1079278 4% 88% 29
5 GPR119 AGONIST authKW 891190 3% 96% 22
6 FFAR1 authKW 747048 3% 84% 21
7 FFA1 authKW 635251 2% 100% 15
8 GPR40 AGONIST authKW 465851 2% 100% 11
9 FFAR4 authKW 435597 2% 86% 12
10 GPR41 authKW 406556 2% 80% 12

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 2667 18% 0% 133
2 Endocrinology & Metabolism 2013 21% 0% 152
3 Pharmacology & Pharmacy 821 21% 0% 155
4 Biochemistry & Molecular Biology 388 23% 0% 164
5 Cell Biology 228 11% 0% 79
6 Chemistry, Organic 189 9% 0% 64
7 Nutrition & Dietetics 175 5% 0% 34
8 Physiology 104 5% 0% 37
9 Biophysics 89 5% 0% 37
10 Agriculture, Dairy & Animal Science 28 2% 0% 14

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENOM DRUG DISCOVERY SCI 141452 3% 16% 21
2 LOMONOSOV FINE CHEM TECHNOL 127050 0% 100% 3
3 PHYSIOL SURUGA KU 95286 0% 75% 3
4 MOL PHARMACOL GRP 91270 4% 7% 29
5 GENOM HISTOL 84700 0% 100% 2
6 TARGET BIOINFORMAT EUROPE 84700 0% 100% 2
7 METAB DIS DRUG DISCOVERY UNIT 76228 0% 60% 3
8 MOL CELL SYST BIOL 69509 4% 6% 29
9 MOL MED THER Y 58812 1% 28% 5
10 GYEONG GI BIO 56465 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ACS MEDICINAL CHEMISTRY LETTERS 6022 2% 1% 14
2 FRONTIERS IN ENDOCRINOLOGY 4641 1% 1% 8
3 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2643 6% 0% 40
4 DIABETES OBESITY & METABOLISM 1907 1% 0% 10
5 JOURNAL OF MEDICINAL CHEMISTRY 1508 4% 0% 28
6 ANNUAL REPORTS IN MEDICINAL CHEMISTRY 1181 1% 1% 5
7 MOLECULAR PHARMACOLOGY 712 2% 0% 13
8 BMC PHARMACOLOGY & TOXICOLOGY 653 0% 1% 2
9 BIOORGANIC & MEDICINAL CHEMISTRY 616 2% 0% 14
10 DIABETES 575 2% 0% 13

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 GPR40 3849202 14% 87% 104 Search GPR40 Search GPR40
2 GPR120 1937940 8% 80% 57 Search GPR120 Search GPR120
3 GPR119 1473035 6% 87% 40 Search GPR119 Search GPR119
4 GPR43 1079278 4% 88% 29 Search GPR43 Search GPR43
5 GPR119 AGONIST 891190 3% 96% 22 Search GPR119+AGONIST Search GPR119+AGONIST
6 FFAR1 747048 3% 84% 21 Search FFAR1 Search FFAR1
7 FFA1 635251 2% 100% 15 Search FFA1 Search FFA1
8 GPR40 AGONIST 465851 2% 100% 11 Search GPR40+AGONIST Search GPR40+AGONIST
9 FFAR4 435597 2% 86% 12 Search FFAR4 Search FFAR4
10 GPR41 406556 2% 80% 12 Search GPR41 Search GPR41

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MILLIGAN, G , SHIMPUKADE, B , ULVEN, T , HUDSON, BD , (2017) COMPLEX PHARMACOLOGY OF FREE FATTY ACID RECEPTORS.CHEMICAL REVIEWS. VOL. 117. ISSUE 1. P. 67 -110 219 60% 2
2 LI, Z , QIU, QQ , GENG, XQ , YANG, JY , HUANG, WL , QIAN, H , (2016) FREE FATTY ACID RECEPTOR AGONISTS FOR THE TREATMENT OF TYPE 2 DIABETES: DRUGS IN PRECLINICAL TO PHASE II CLINICAL DEVELOPMENT.EXPERT OPINION ON INVESTIGATIONAL DRUGS. VOL. 25. ISSUE 8. P. 871 -890 84 75% 3
3 WATTERSON, KR , HUDSON, BD , ULVEN, T , MILLIGAN, G , (2014) TREATMENT OF TYPE 2 DIABETES BY FREE FATTY ACID RECEPTOR AGONISTS.FRONTIERS IN ENDOCRINOLOGY. VOL. 5. ISSUE . P. - 77 86% 20
4 RITTER, K , BUNING, C , HALLAND, N , POVERLEIN, C , SCHWINK, L , (2016) G PROTEIN-COUPLED RECEPTOR 119 (GPR119) AGONISTS FOR THE TREATMENT OF DIABETES: RECENT PROGRESS AND PREVAILING CHALLENGES.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 59. ISSUE 8. P. 3579 -3592 64 89% 3
5 MILLIGAN, G , ALVAREZ-CURTO, E , WATTERSON, KR , ULVEN, T , HUDSON, BD , (2015) CHARACTERIZING PHARMACOLOGICAL LIGANDS TO STUDY THE LONG-CHAIN FATTY ACID RECEPTORS GPR40/FFA1 AND GPR120/FFA4.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 172. ISSUE 13. P. 3254 -3265 68 85% 12
6 HARA, T , KIMURA, I , INOUE, D , ICHIMURA, A , HIRASAWA, A , (2013) FREE FATTY ACID RECEPTORS AND THEIR ROLE IN REGULATION OF ENERGY METABOLISM.REVIEWS OF PHYSIOLOGY, BIOCHEMISTRY AND PHARMACOLOGY, VOL 164. VOL. 164. ISSUE . P. 77-116 84 71% 23
7 MANCINI, AD , POITOUT, V , (2015) GPR40 AGONISTS FOR THE TREATMENT OF TYPE 2 DIABETES: LIFE AFTER 'TAKING' A HIT.DIABETES OBESITY & METABOLISM. VOL. 17. ISSUE 7. P. 622 -629 60 77% 21
8 YONEZAWA, T , KURATA, R , YOSHIDA, K , MURAYAMA, MA , CUI, XF , HASEGAWA, A , (2013) FREE FATTY ACIDS-SENSING G PROTEIN-COUPLED RECEPTORS IN DRUG TARGETING AND THERAPEUTICS.CURRENT MEDICINAL CHEMISTRY. VOL. 20. ISSUE 31. P. 3855-3871 78 64% 31
9 MOHAMMAD, S , (2016) GPR40 AGONISTS FOR THE TREATMENT OF TYPE 2 DIABETES MELLITUS: BENEFITS AND CHALLENGES.CURRENT DRUG TARGETS. VOL. 17. ISSUE 11. P. 1292 -1300 71 77% 0
10 HARA, T , KASHIHARA, D , ICHIMURA, A , KIMURA, I , TSUJIMOTO, G , HIRASAWA, A , (2014) ROLE OF FREE FATTY ACID RECEPTORS IN THE REGULATION OF ENERGY METABOLISM.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1841. ISSUE 9. P. 1292 -1300 62 70% 36

Classes with closest relation at Level 1


Rank Class id link
1 13751 GLUCOLIPOTOXICITY//LIPOTOXICITY//BETA CELL BIOCHEM
2 28909 GPRC5A//GPR12//GPR139
3 1386 GUT MICROBIOTA//PREBIOTICS//METAB NUTR GRP
4 376 GLUCAGON LIKE PEPTIDE 1//GLP 1//INCRETIN
5 9437 6 N PROPYLTHIOURACIL//PROP//FAT TASTE
6 26108 BIOCHEM TECHNOL SCI TECHNOL//GPR35//RESONANT WAVEGUIDE GRATING BIOSENSOR
7 12751 NIACIN//LAROPIPRANT//GPR109A
8 7109 BUTYRATE//SODIUM BUTYRATE//DIVERSION COLITIS
9 20665 SUCROSE RICH DIET//ADIPOSE TISSUE BIOL//LONG CHAIN MONOUNSATURATED FATTY ACIDS
10 4196 G PROTEIN COUPLED RECEPTOR//GPCR//MEMBRANE PROT STRUCT FUNCT UNIT

Go to start page