Class information for:
Level 1: CHRNA7//ALPHA 7//ALPHA 7 NICOTINIC RECEPTOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12662 890 53.9 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
305 3       NICOTINIC ACETYLCHOLINE RECEPTOR//BENZODIAZEPINES//NICOTINIC RECEPTORS 40571
1265 2             NICOTINE//NICOTINIC RECEPTORS//NICOTINIC ACETYLCHOLINE RECEPTOR 8795
12662 1                   CHRNA7//ALPHA 7//ALPHA 7 NICOTINIC RECEPTOR 890

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHRNA7 authKW 899852 4% 66% 40
2 ALPHA 7 authKW 561321 5% 38% 43
3 ALPHA 7 NICOTINIC RECEPTOR authKW 478687 4% 36% 39
4 ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR authKW 396715 5% 25% 47
5 GTS 21 authKW 386142 2% 51% 22
6 ALPHA 7 NACHR authKW 323235 4% 27% 35
7 PNU 120596 authKW 308765 1% 75% 12
8 NICOTINIC RECEPTORS authKW 262187 12% 7% 107
9 CHRFAM7A authKW 228713 1% 67% 10
10 ALPHA7 NICOTINIC RECEPTOR authKW 190591 1% 56% 10

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 5199 45% 0% 398
2 Pharmacology & Pharmacy 2875 34% 0% 304
3 Psychiatry 920 12% 0% 111
4 Chemistry, Medicinal 913 10% 0% 90
5 Biochemistry & Molecular Biology 133 15% 0% 130
6 Genetics & Heredity 100 6% 0% 52
7 Clinical Neurology 81 6% 0% 51
8 Behavioral Sciences 71 2% 0% 22
9 Geriatrics & Gerontology 61 2% 0% 15
10 Chemistry, Organic 55 5% 0% 47

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PSYCHIAT C268 71 102924 0% 100% 3
2 R47W 72644 1% 35% 6
3 TSU AGING 68616 0% 100% 2
4 CHEM SCI NEUROSCI DISCOVERY 45743 0% 67% 2
5 NEUROSCI DK 45739 0% 33% 4
6 NEUROTEC MOL NEUROPHARMACOL 44107 0% 43% 3
7 EXCELLENCE PL BIOL 35401 1% 13% 8
8 ANTI INFLAMMATORY SIGNALING 34308 0% 100% 1
9 ASSAYS ARRAYS RD 34308 0% 100% 1
10 CENT NERVOUS SYST NEUROL DIS 34308 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUROPHARMACOLOGY 5819 4% 0% 40
2 JOURNAL OF MOLECULAR NEUROSCIENCE 2454 2% 1% 14
3 SLAS DISCOVERY 1632 0% 5% 1
4 BIOCHEMICAL PHARMACOLOGY 1415 3% 0% 28
5 NEUROPSYCHOPHARMACOLOGY 1303 2% 0% 14
6 ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES 1246 1% 1% 5
7 MOLECULAR PHARMACOLOGY 1240 2% 0% 19
8 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 1236 3% 0% 28
9 BRAIN CELL BIOLOGY 978 0% 3% 1
10 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 952 3% 0% 27

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CHRNA7 899852 4% 66% 40 Search CHRNA7 Search CHRNA7
2 ALPHA 7 561321 5% 38% 43 Search ALPHA+7 Search ALPHA+7
3 ALPHA 7 NICOTINIC RECEPTOR 478687 4% 36% 39 Search ALPHA+7+NICOTINIC+RECEPTOR Search ALPHA+7+NICOTINIC+RECEPTOR
4 ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR 396715 5% 25% 47 Search ALPHA+7+NICOTINIC+ACETYLCHOLINE+RECEPTOR Search ALPHA+7+NICOTINIC+ACETYLCHOLINE+RECEPTOR
5 GTS 21 386142 2% 51% 22 Search GTS+21 Search GTS+21
6 ALPHA 7 NACHR 323235 4% 27% 35 Search ALPHA+7+NACHR Search ALPHA+7+NACHR
7 PNU 120596 308765 1% 75% 12 Search PNU+120596 Search PNU+120596
8 NICOTINIC RECEPTORS 262187 12% 7% 107 Search NICOTINIC+RECEPTORS Search NICOTINIC+RECEPTORS
9 CHRFAM7A 228713 1% 67% 10 Search CHRFAM7A Search CHRFAM7A
10 ALPHA7 NICOTINIC RECEPTOR 190591 1% 56% 10 Search ALPHA7+NICOTINIC+RECEPTOR Search ALPHA7+NICOTINIC+RECEPTOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BERTRAND, D , LEE, CHL , FLOOD, D , MARGER, F , DONNELLY-ROBERTS, D , (2015) THERAPEUTIC POTENTIAL OF ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTORS.PHARMACOLOGICAL REVIEWS. VOL. 67. ISSUE 4. P. 1025 -1073 179 35% 10
2 WALLACE, TL , PORTER, RHP , (2011) TARGETING THE NICOTINIC ALPHA7 ACETYLCHOLINE RECEPTOR TO ENHANCE COGNITION IN DISEASE.BIOCHEMICAL PHARMACOLOGY. VOL. 82. ISSUE 8. P. 891-903 83 53% 102
3 HASHIMOTO, K , (2015) TARGETING OF ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTORS IN THE TREATMENT OF SCHIZOPHRENIA AND THE USE OF AUDITORY SENSORY GATING AS A TRANSLATIONAL BIOMARKER.CURRENT PHARMACEUTICAL DESIGN. VOL. 21. ISSUE 26. P. 3797 -3806 70 56% 9
4 UTESHEV, VV , (2016) ALLOSTERIC MODULATION OF NICOTINIC ACETYLCHOLINE RECEPTORS: THE CONCEPT AND THERAPEUTIC TRENDS.CURRENT PHARMACEUTICAL DESIGN. VOL. 22. ISSUE 14. P. 1986 -1997 95 40% 1
5 THOMSEN, MS , HANSEN, HH , TIMMERMAN, DB , MIKKELSEN, JD , (2010) COGNITIVE IMPROVEMENT BY ACTIVATION OF ALPHA(7) NICOTINIC ACETYLCHOLINE RECEPTORS: FROM ANIMAL MODELS TO HUMAN PATHOPHYSIOLOGY.CURRENT PHARMACEUTICAL DESIGN. VOL. 16. ISSUE 3. P. 323-343 96 35% 100
6 CORRADI, J , BOUZAT, C , (2016) UNDERSTANDING THE BASES OF FUNCTION AND MODULATION OF ALPHA 7 NICOTINIC RECEPTORS: IMPLICATIONS FOR DRUG DISCOVERY.MOLECULAR PHARMACOLOGY. VOL. 90. ISSUE 3. P. 288 -299 70 40% 4
7 MAZUROV, AA , SPEAKE, JD , YOHANNES, D , (2011) DISCOVERY AND DEVELOPMENT OF ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 54. ISSUE 23. P. 7943 -7961 50 69% 30
8 SINKUS, ML , GRAW, S , FREEDMAN, R , ROSS, RG , LESTER, HA , LEONARD, S , (2015) THE HUMAN CHRNA7 AND CHRFAM7A GENES: A REVIEW OF THE GENETICS, REGULATION, AND FUNCTION.NEUROPHARMACOLOGY. VOL. 96. ISSUE . P. 274 -288 65 36% 15
9 HAYDAR, SN , DUNLOP, J , (2010) NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS - TARGETS FOR THE DEVELOPMENT OF DRUGS TO TREAT COGNITIVE IMPAIRMENT ASSOCIATED WITH SCHIZOPHRENIA AND ALZHEIMER'S DISEASE.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 10. ISSUE 2. P. 144-152 40 70% 54
10 HAJOS, M , ROGERS, BN , (2010) TARGETING ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTORS IN THE TREATMENT OF SCHIZOPHRENIA.CURRENT PHARMACEUTICAL DESIGN. VOL. 16. ISSUE 5. P. 538-554 69 39% 50

Classes with closest relation at Level 1


Rank Class id link
1 111 NICOTINE//NICOTINIC RECEPTORS//MECAMYLAMINE
2 15123 SENSORY GATING//P50//P50 SUPPRESSION
3 6766 CHOLINERGIC ANTI INFLAMMATORY PATHWAY//NON NEURONAL CHOLINERGIC SYSTEM//ALPHA 7 NACHR
4 9955 EPIBATIDINE//ABT 594//A 85380
5 22367 CELLULAR NEUROSCI NEURODEGENERAT REPAIR PROGRAM//AMYLOID BETA PEPTIDE 25 35//AMYLOID BETA PROTEIN OLIGOMERS
6 754 CYS LOOP RECEPTOR//NICOTINIC ACETYLCHOLINE RECEPTOR//RECEPTOR BIOL
7 10380 XANOMELINE//M 1//ALCURONIUM
8 14976 5 CSRTT//5 CHOICE SERIAL REACTION TIME TASK//REVERSAL LEARNING
9 6562 NICOTINE DEPENDENCE//SMOKING//SMOKING CESSATION
10 20963 GLUTAMINYL CYCLASE//INTRANEURONAL A BETA//PYROGLUTAMATE

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