Class information for:
Level 1: ACAT INHIBITOR//ACYL COA CHOLESTEROL ACYLTRANSFERASE//ACAT

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12318 915 34.5 67%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
171 3       MONASCUS//CITRININ//MONASCUS PURPUREUS 58457
43 2             JOURNAL OF LIPID RESEARCH//HDL//LIPOPROTEINS 30963
12318 1                   ACAT INHIBITOR//ACYL COA CHOLESTEROL ACYLTRANSFERASE//ACAT 915

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ACAT INHIBITOR authKW 1266696 6% 72% 53
2 ACYL COA CHOLESTEROL ACYLTRANSFERASE authKW 560271 4% 44% 38
3 ACAT authKW 414073 5% 28% 44
4 ACYL COA CHOLESTEROL ACYLTRANSFERASE ACAT authKW 310599 1% 85% 11
5 ARTERIOSCLEROSIS PROGRAM address 270299 1% 90% 9
6 ACAT2 authKW 256335 1% 59% 13
7 AVASIMIBE authKW 245725 1% 82% 9
8 ACYL COA CHOLESTEROL ACYLTRANSFERASE ACAT INHIBITOR authKW 233593 1% 100% 7
9 F 1394 authKW 200223 1% 100% 6
10 ACYL COENZYME A CHOLESTEROL ACYLTRANSFERASE authKW 197570 2% 39% 15

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 2424 16% 0% 144
2 Biochemistry & Molecular Biology 1838 39% 0% 355
3 Pharmacology & Pharmacy 1133 22% 0% 204
4 Peripheral Vascular Diseases 991 10% 0% 94
5 Biophysics 566 10% 0% 91
6 Cardiac & Cardiovascular System 236 8% 0% 69
7 Nutrition & Dietetics 221 5% 0% 43
8 Chemistry, Organic 196 8% 0% 75
9 Biotechnology & Applied Microbiology 63 5% 0% 46
10 Microbiology 62 5% 0% 45

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ARTERIOSCLEROSIS PROGRAM 270299 1% 90% 9
2 SECT LIPID SCI 111513 2% 18% 19
3 ATHEROSCLEROSIS THER EUT 75082 0% 75% 3
4 ATHEROSCLEROSIS PROGRAM 69516 1% 42% 5
5 SCREENING NEW MICROBIAL DRUGS 42901 0% 43% 3
6 BIOL EXPLORAT 33370 0% 100% 1
7 BIOL EXPLORATOIRE 33370 0% 100% 1
8 BIOSCI NUTR NUTR TOXICOLNOVUMKAROL 33370 0% 100% 1
9 CHEM MONELL CHEM SENSES 33370 0% 100% 1
10 DIABET LIPID PROGRAM 33370 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF LIPID RESEARCH 14070 7% 1% 60
2 JOURNAL OF ANTIBIOTICS 7981 4% 1% 40
3 ATHEROSCLEROSIS 5239 4% 0% 41
4 LIPIDS 4728 3% 0% 29
5 BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM 3741 1% 1% 11
6 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 2130 2% 0% 22
7 JOURNAL OF MEDICINAL CHEMISTRY 1966 4% 0% 36
8 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 1573 4% 0% 35
9 JAPANESE JOURNAL OF PHARMACOLOGY 1471 2% 0% 14
10 BIOCHIMICA ET BIOPHYSICA ACTA 1296 4% 0% 34

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ACAT INHIBITOR 1266696 6% 72% 53 Search ACAT+INHIBITOR Search ACAT+INHIBITOR
2 ACYL COA CHOLESTEROL ACYLTRANSFERASE 560271 4% 44% 38 Search ACYL+COA+CHOLESTEROL+ACYLTRANSFERASE Search ACYL+COA+CHOLESTEROL+ACYLTRANSFERASE
3 ACAT 414073 5% 28% 44 Search ACAT Search ACAT
4 ACYL COA CHOLESTEROL ACYLTRANSFERASE ACAT 310599 1% 85% 11 Search ACYL+COA+CHOLESTEROL+ACYLTRANSFERASE+ACAT Search ACYL+COA+CHOLESTEROL+ACYLTRANSFERASE+ACAT
5 ACAT2 256335 1% 59% 13 Search ACAT2 Search ACAT2
6 AVASIMIBE 245725 1% 82% 9 Search AVASIMIBE Search AVASIMIBE
7 ACYL COA CHOLESTEROL ACYLTRANSFERASE ACAT INHIBITOR 233593 1% 100% 7 Search ACYL+COA+CHOLESTEROL+ACYLTRANSFERASE+ACAT+INHIBITOR Search ACYL+COA+CHOLESTEROL+ACYLTRANSFERASE+ACAT+INHIBITOR
8 F 1394 200223 1% 100% 6 Search F+1394 Search F+1394
9 ACYL COENZYME A CHOLESTEROL ACYLTRANSFERASE 197570 2% 39% 15 Search ACYL+COENZYME+A+CHOLESTEROL+ACYLTRANSFERASE Search ACYL+COENZYME+A+CHOLESTEROL+ACYLTRANSFERASE
10 CHOLESTEROL ACYLTRANSFERASE 192859 2% 34% 17 Search CHOLESTEROL+ACYLTRANSFERASE Search CHOLESTEROL+ACYLTRANSFERASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 OHSHIRO, T , TOMODA, H , (2011) ISOFORM-SPECIFIC INHIBITORS OF ACATS: RECENT ADVANCES AND PROMISING DEVELOPMENTS.FUTURE MEDICINAL CHEMISTRY. VOL. 3. ISSUE 16. P. 2039 -2061 107 78% 12
2 PAL, P , GANDHI, H , GIRIDHAR, R , YADAV, MR , (2013) ACAT INHIBITORS: THE SEARCH FOR NOVEL CHOLESTEROL LOWERING AGENTS.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 13. ISSUE 8. P. 1195-1219 89 79% 5
3 CHANG, TY , LI, BL , CHANG, CCY , URANO, Y , (2009) ACYL-COENZYME A: CHOLESTEROL ACYLTRANSFERASES.AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. VOL. 297. ISSUE 1. P. E1-E9 69 71% 117
4 PRAMFALK, C , ERIKSSON, M , PARINI, P , (2012) CHOLESTERYL ESTERS AND ACAT.EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY. VOL. 114. ISSUE 6. P. 624-633 62 78% 7
5 ALEGRET, M , LLAVERIAS, G , SILVESTRE, JS , (2004) ACYL COENZYME A : CHOLESTEROL ACYLTRANSFERASE INHIBITORS AS HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC DRUGS.METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY. VOL. 26. ISSUE 7. P. 563-586 85 67% 23
6 BUHMAN, KF , ACCAD, M , FARESE, RV , (2000) MAMMALIAN ACYL-COA: CHOLESTEROL ACYLTRANSFERASES.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1529. ISSUE 1-3. P. 142-154 58 73% 125
7 BUHMAN, KK , CHEN, HC , FARESE, RV , (2001) THE ENZYMES OF NEUTRAL LIPID SYNTHESIS.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 276. ISSUE 44. P. 40369 -40372 51 75% 91
8 CHANG, TY , CHANG, CCY , LIN, S , YU, CJ , LI, BL , MIYAZAKI, A , (2001) ROLES OF ACYL-COENZYME A : CHOLESTEROL ACYLTRANSFERASE-1 AND-2.CURRENT OPINION IN LIPIDOLOGY. VOL. 12. ISSUE 3. P. 289-296 45 80% 136
9 OHSHIRO, T , MATSUDA, D , SAKAI, K , DEGIROLAMO, C , YAGYU, H , RUDEL, LL , OMURA, S , ISHIBASHI, S , TOMODA, H , (2011) PYRIPYROPENE A, AN ACYL-COENZYME A: CHOLESTEROL ACYLTRANSFERASE 2-SELECTIVE INHIBITOR, ATTENUATES HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS IN MURINE MODELS OF HYPERLIPIDEMIA.ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. VOL. 31. ISSUE 5. P. 1108-U436 32 89% 28
10 LEON, C , HILL, JS , WASAN, KM , (2005) POTENTIAL ROLE OF ACYL-COENZYME A : CHOLESTEROL TRANSFERASE (ACAT) INHIBITORS AS HYPOLIPIDEMIC AND ANTIATHEROSCLEROSIS DRUGS.PHARMACEUTICAL RESEARCH. VOL. 22. ISSUE 10. P. 1578-1588 55 59% 45

Classes with closest relation at Level 1


Rank Class id link
1 19790 BILE SALT DEPENDENT LIPASE//CARBAMATE INHIBITORS//BILE SALT STIMULATED LIPASE
2 10312 ARTERIOSCLEROSIS//PATOCYTOSIS//SPECIALIZED ATHEROSCLEROSIS
3 23598 LOW CASEIN DIET//INVERSE GATED DECOUPLING//SERUM ORNITHINE CARBAMOYLTRANSFERASE
4 17349 DGAT 1 INHIBITOR//MONOACYLGLYCEROL ACYLTRANSFERASE//DGAT
5 34646 DIETARY FAT AND OILS//ENDOGENOUS LIPASE ACTIVITY//ETHYL ESTRADIOL
6 17284 WHHL RABBIT//WHHLMI RABBIT//PATHOPHARMACOL UNIT
7 3142 MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN//APOLIPOPROTEIN B//HYPOBETALIPOPROTEINEMIA
8 13816 HMG COA REDUCTASE//APOMINE//FOOD FUS COMPLEX
9 21799 6 PI AZAELECTROCYCLIZATION//TRICYCLIC PYRONES//ARISUGACIN A
10 9039 CEREBROTENDINOUS XANTHOMATOSIS//CHOLESTEROL 7 ALPHA HYDROXYLASE//STEROL 27 HYDROXYLASE

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