Class information for:
Level 1: SERTINDOLE//TORSADES DE POINTES//TORSADE DE POINTES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11919 945 34.4 71%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
11 3       ATRIAL FIBRILLATION//CARDIAC & CARDIOVASCULAR SYSTEM//CATHETER ABLATION 130936
1064 2             LONG QT SYNDROME//BRUGADA SYNDROME//QT INTERVAL 10012
11919 1                   SERTINDOLE//TORSADES DE POINTES//TORSADE DE POINTES 945

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SERTINDOLE authKW 720270 6% 42% 53
2 TORSADES DE POINTES authKW 380100 8% 15% 78
3 TORSADE DE POINTES authKW 373156 8% 16% 74
4 QT PROLONGATION authKW 295110 6% 15% 59
5 QTC PROLONGATION authKW 188694 3% 23% 25
6 PSYCHOPHARMACOL VENTURE address 161555 1% 100% 5
7 QT INTERVAL authKW 140645 8% 6% 71
8 QT INTERVAL PROLONGATION authKW 72786 1% 17% 13
9 CLIN TOXICOL PHARMACOL address 66196 2% 12% 17
10 DRUG INDUCED QTC INTERVAL PROLONGATION authKW 64622 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 4355 40% 0% 380
2 Psychiatry 3685 23% 0% 218
3 Cardiac & Cardiovascular System 1592 17% 0% 161
4 Medicine, General & Internal 647 13% 0% 127
5 Emergency Medicine 350 3% 0% 26
6 Toxicology 297 6% 0% 57
7 Critical Care Medicine 119 3% 0% 24
8 Clinical Neurology 72 5% 0% 51
9 Medicine, Legal 59 1% 0% 9
10 Psychology, Clinical 45 2% 0% 19

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PSYCHOPHARMACOL VENTURE 161555 1% 100% 5
2 CLIN TOXICOL PHARMACOL 66196 2% 12% 17
3 EA NEUROCARDIOL PHYSIOPATHOL TROUBLES RYTHME CARD 64622 0% 100% 2
4 KENT DEV 64622 0% 100% 2
5 ABT PEDIATR KARDIOL 32311 0% 100% 1
6 ABT VERSORGUNGS FOR 32311 0% 100% 1
7 ANESTHESIOL CRIT CARE MEDARMSTRONG P 32311 0% 100% 1
8 ATTIKON GEN HOSPCLIN MOL PSYCHOGENET UNIT 32311 0% 100% 1
9 BLACKROCK 32311 0% 100% 1
10 CARDIOLST ANTONIUS HOSP NIEUWEGEIN 32311 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 6738 2% 1% 22
2 JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 5236 2% 1% 21
3 PSYCHOPHARMAKOTHERAPIE 4145 1% 2% 8
4 INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE 3209 1% 1% 9
5 PHARMACOTHERAPY 3109 2% 0% 21
6 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 2866 3% 0% 27
7 DRUG SAFETY 2596 1% 1% 13
8 INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY 2515 1% 1% 12
9 JOURNAL OF CLINICAL PSYCHIATRY 1617 2% 0% 19
10 EXPERT OPINION ON DRUG SAFETY 1516 1% 1% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SERTINDOLE 720270 6% 42% 53 Search SERTINDOLE Search SERTINDOLE
2 TORSADES DE POINTES 380100 8% 15% 78 Search TORSADES+DE+POINTES Search TORSADES+DE+POINTES
3 TORSADE DE POINTES 373156 8% 16% 74 Search TORSADE+DE+POINTES Search TORSADE+DE+POINTES
4 QT PROLONGATION 295110 6% 15% 59 Search QT+PROLONGATION Search QT+PROLONGATION
5 QTC PROLONGATION 188694 3% 23% 25 Search QTC+PROLONGATION Search QTC+PROLONGATION
6 QT INTERVAL 140645 8% 6% 71 Search QT+INTERVAL Search QT+INTERVAL
7 QT INTERVAL PROLONGATION 72786 1% 17% 13 Search QT+INTERVAL+PROLONGATION Search QT+INTERVAL+PROLONGATION
8 DRUG INDUCED QTC INTERVAL PROLONGATION 64622 0% 100% 2 Search DRUG+INDUCED+QTC+INTERVAL+PROLONGATION Search DRUG+INDUCED+QTC+INTERVAL+PROLONGATION
9 HERG BLOCKADE 64622 0% 100% 2 Search HERG+BLOCKADE Search HERG+BLOCKADE
10 PROLONGATION OF QT INTERVAL 64622 0% 100% 2 Search PROLONGATION+OF+QT+INTERVAL Search PROLONGATION+OF+QT+INTERVAL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 HASNAIN, M , VIEWEG, WVR , (2014) QTC INTERVAL PROLONGATION AND TORSADE DE POINTES ASSOCIATED WITH SECOND-GENERATION ANTIPSYCHOTICS AND ANTIDEPRESSANTS: A COMPREHENSIVE REVIEW.CNS DRUGS. VOL. 28. ISSUE 10. P. 887 -920 68 39% 19
2 ZELTSER, D , JUSTO, D , HALKIN, A , PROKHOROV, F , HELLER, K , VISKIN, S , (2003) TORSADE DE POINTES DUE TO NONCARDIAC DRUGS - MOST PATIENTS HAVE EASILY IDENTIFIABLE RISK FACTORS.MEDICINE. VOL. 82. ISSUE 4. P. 282-290 62 53% 108
3 GUO, DH , CAI, Y , CHAI, D , LIANG, BB , BAI, N , WANG, R , (2010) THE CARDIOTOXICITY OF MACROLIDES: A SYSTEMATIC REVIEW.PHARMAZIE. VOL. 65. ISSUE 9. P. 631-640 34 77% 12
4 ZOCCALI, RA , BRUNO, A , MUSCATELLO, MRA , (2015) EFFICACY AND SAFETY OF SERTINDOLE IN SCHIZOPHRENIA A CLINICAL REVIEW.JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. VOL. 35. ISSUE 3. P. 286 -295 41 53% 0
5 TITIER, K , GIRODET, PO , VERDOUX, H , MOLIMARD, M , BEGAUD, B , HAVERKAMP, W , LADER, M , MOORE, N , (2005) ATYPICAL ANTIPSYCHOTICS - FROM POTASSIUM CHANNELS TO TORSADE DE POINTES AND SUDDEN DEATH.DRUG SAFETY. VOL. 28. ISSUE 1. P. 35-51 44 57% 57
6 JUSTO, D , ZELTSER, D , (2006) TORSADES DE POINTES INDUCED BY ANTIBIOTICS.EUROPEAN JOURNAL OF INTERNAL MEDICINE. VOL. 17. ISSUE 4. P. 254-259 38 66% 13
7 BEACH, SR , CELANO, CM , NOSEWORTHY, PA , JANUZZI, JL , HUFFMAN, JC , (2013) QTC PROLONGATION, TORSADES DE POINTES, AND PSYCHOTROPIC MEDICATIONS.PSYCHOSOMATICS. VOL. 54. ISSUE 1. P. 1 -13 33 45% 61
8 OWENS, RC , (2004) QT PROLONGATION WITH ANTIMICROBIAL AGENTS - UNDERSTANDING THE SIGNIFICANCE.DRUGS. VOL. 64. ISSUE 10. P. 1091-1124 52 43% 65
9 CALDERONE, V , TESTAI, L , MARTINOTTI, E , DEL TACCA, M , BRESCHI, MC , (2005) DRUG-INDUCED BLOCK OF CARDIAC HERG POTASSIUM CHANNELS AND DEVELOPMENT OF TORSADE DE POINTES ARRHYTHMIAS: THE CASE OF ANTIPSYCHOTICS.JOURNAL OF PHARMACY AND PHARMACOLOGY. VOL. 57. ISSUE 2. P. 151-161 36 64% 12
10 SCHACHTELE, S , TUMENA, T , GASSMANN, KG , FROMM, MF , MAAS, R , (2016) CO-PRESCRIPTION OF QT-INTERVAL PROLONGING DRUGS: AN ANALYSIS IN A LARGE COHORT OF GERIATRIC PATIENTS.PLOS ONE. VOL. 11. ISSUE 5. P. - 26 68% 0

Classes with closest relation at Level 1


Rank Class id link
1 3490 HERG//I KR//HERG CHANNEL
2 25816 HEART QT INTERVAL//ELECTROCARDIOGRAPHY QT INTERVAL//TORSADOGENIC ACTION
3 30562 GALACTOGOGUE//DOMPERIDONE//RELACTATION
4 2028 QT DISPERSION//QT INTERVAL//REPOLARIZATION
5 1859 LONG QT SYNDROME//KCNQ1//SHORT QT SYNDROME
6 20744 ASENAPINE//ZIPRASIDONE//LURASIDONE
7 10622 CYCLIC ANTIDEPRESSANT//AMITRIPTYLINE POISONING//TRICYCLIC ANTIDEPRESSANTS
8 14377 COCHRANE IZOPHRENIA GRP//ACUTE AGITATION//SCHIZOPHRENIA DRUG THERAPY
9 7609 9 HYDROXYRISPERIDONE//NORCLOZAPINE//CLOZAPINE
10 28567 CODISPENSING//RISK EVALUATION AND MITIGATION STRATEGIES//BOXED WARNINGS

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