Class information for:
Level 1: N SUBSTITUTED PIPERAZINYL QUINOLONES//S ENOKI 3394//FLUOROQUINOLONES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11697 961 23.2 61%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
233 3       JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY//ANTIMICROBIAL AGENTS AND CHEMOTHERAPY//FLUOROQUINOLONES 48717
889 2             FLUOROQUINOLONES//QUINOLONES//CIPROFLOXACIN 11411
11697 1                   N SUBSTITUTED PIPERAZINYL QUINOLONES//S ENOKI 3394//FLUOROQUINOLONES 961

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 N SUBSTITUTED PIPERAZINYL QUINOLONES authKW 158865 1% 100% 5
2 S ENOKI 3394 address 142976 1% 75% 6
3 FLUOROQUINOLONES authKW 133104 11% 4% 104
4 DW286 authKW 132386 1% 83% 5
5 PIPERAZINYL QUINOLONES authKW 127092 0% 100% 4
6 QUINOLONES authKW 118793 8% 5% 76
7 REDUCTIVE LACTAMIZATION authKW 101672 0% 80% 4
8 4 OXOTHIENO2 3 BPYRIDINES authKW 95319 0% 100% 3
9 AMINOCYCLOPROPYL SUBSTITUENT authKW 95319 0% 100% 3
10 TRICYCLIC FLUOROQUINOLONE authKW 95319 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 14772 37% 0% 353
2 Chemistry, Organic 7539 40% 0% 386
3 Pharmacology & Pharmacy 1087 21% 0% 206
4 Chemistry, Multidisciplinary 996 23% 0% 219
5 Microbiology 90 6% 0% 53
6 Crystallography 26 2% 0% 20
7 Chemistry, Inorganic & Nuclear 24 3% 0% 28
8 Infectious Diseases 17 2% 0% 20
9 Chemistry, Applied 6 2% 0% 15
10 Spectroscopy 0 1% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 S ENOKI 3394 142976 1% 75% 6
2 INSERM 0004 63546 0% 100% 2
3 QUIM ORGAN 210 47657 0% 50% 3
4 INSERM 511 42363 0% 67% 2
5 BIOL BIOINFORMAT 39100 0% 31% 4
6 BEIJING DRUG ISTANCE TB PHARM 31773 0% 100% 1
7 BIOL S MINAMI KU 31773 0% 100% 1
8 BOMMASANDRA IND AREA 49 31773 0% 100% 1
9 CD NENITESCU ORGAN CHIMISTRY 31773 0% 100% 1
10 EA 2414 PHARMACOL BIOMOL 31773 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF HETEROCYCLIC CHEMISTRY 22623 9% 1% 88
2 JOURNAL OF MEDICINAL CHEMISTRY 14470 10% 0% 99
3 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 7490 5% 1% 47
4 CHEMICAL & PHARMACEUTICAL BULLETIN 4926 5% 0% 52
5 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 3752 6% 0% 55
6 SOUTH AFRICAN JOURNAL OF CHEMISTRY-SUID-AFRIKAANSE TYDSKRIF VIR CHEMIE 2777 1% 1% 8
7 MEDICINAL CHEMISTRY RESEARCH 1938 1% 0% 14
8 FARMACO-EDIZIONE SCIENTIFICA 1864 1% 1% 7
9 ARCHIV DER PHARMAZIE 1424 1% 0% 14
10 HETEROCYCLES 1240 2% 0% 23

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 N SUBSTITUTED PIPERAZINYL QUINOLONES 158865 1% 100% 5 Search N+SUBSTITUTED+PIPERAZINYL+QUINOLONES Search N+SUBSTITUTED+PIPERAZINYL+QUINOLONES
2 FLUOROQUINOLONES 133104 11% 4% 104 Search FLUOROQUINOLONES Search FLUOROQUINOLONES
3 DW286 132386 1% 83% 5 Search DW286 Search DW286
4 PIPERAZINYL QUINOLONES 127092 0% 100% 4 Search PIPERAZINYL+QUINOLONES Search PIPERAZINYL+QUINOLONES
5 QUINOLONES 118793 8% 5% 76 Search QUINOLONES Search QUINOLONES
6 REDUCTIVE LACTAMIZATION 101672 0% 80% 4 Search REDUCTIVE+LACTAMIZATION Search REDUCTIVE+LACTAMIZATION
7 4 OXOTHIENO2 3 BPYRIDINES 95319 0% 100% 3 Search 4+OXOTHIENO2+3+BPYRIDINES Search 4+OXOTHIENO2+3+BPYRIDINES
8 AMINOCYCLOPROPYL SUBSTITUENT 95319 0% 100% 3 Search AMINOCYCLOPROPYL+SUBSTITUENT Search AMINOCYCLOPROPYL+SUBSTITUENT
9 TRICYCLIC FLUOROQUINOLONE 95319 0% 100% 3 Search TRICYCLIC+FLUOROQUINOLONE Search TRICYCLIC+FLUOROQUINOLONE
10 CIPROFLOXACIN DERIVATIVES 84725 0% 67% 4 Search CIPROFLOXACIN+DERIVATIVES Search CIPROFLOXACIN+DERIVATIVES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 RADL, S , BOUZARD, D , (1992) RECENT ADVANCES IN THE SYNTHESIS OF ANTIBACTERIAL QUINOLONES.HETEROCYCLES. VOL. 34. ISSUE 11. P. 2143-2177 74 93% 50
2 AKHTAR, R , YOUSAF, M , NAQVI, SAR , IRFAN, M , ZAHOOR, AF , HUSSAIN, AI , CHATHA, SAS , (2016) SYNTHESIS OF CIPROFLOXACIN-BASED COMPOUNDS: A REVIEW.SYNTHETIC COMMUNICATIONS. VOL. 46. ISSUE 23. P. 1849 -1879 40 63% 0
3 MOKRUSHINA, GA , NOSOVA, EV , LIPUNOVA, GN , CHARUSHIN, VN , (1999) POLYCYCLIC FLUOROQUINOLONES.ZHURNAL ORGANICHESKOI KHIMII. VOL. 35. ISSUE 10. P. 1447 -1463 44 88% 9
4 LEYSEN, DC , ZHANG, MQ , HAEMERS, A , BOLLAERT, W , (1991) SYNTHESIS OF ANTIBACTERIAL 4-QUINOLONE-3-CARBOXYLIC ACIDS AND THEIR DERIVATIVES .1..PHARMAZIE. VOL. 46. ISSUE 7. P. 485-501 50 81% 13
5 LEYSEN, DC , ZHANG, MQ , HAEMERS, A , BOLLAERT, W , (1991) SYNTHESIS OF ANTIBACTERIAL 4-QUINOLONE-3-CARBOXYLIC ACIDS AND THEIR DERIVATIVES .2..PHARMAZIE. VOL. 46. ISSUE 8. P. 557-572 49 80% 10
6 ZHANG, MQ , HAEMERS, A , (1991) QUINOLONE ANTIMICROBIAL AGENTS - STRUCTURE-ACTIVITY-RELATIONSHIPS.PHARMAZIE. VOL. 46. ISSUE 10. P. 687-700 46 73% 18
7 RADL, S , (1990) STRUCTURE-ACTIVITY-RELATIONSHIPS IN DNA GYRASE INHIBITORS.PHARMACOLOGY & THERAPEUTICS. VOL. 48. ISSUE 1. P. 1-17 58 58% 40
8 GOOTZ, TD , BRIGHTY, KE , (1996) FLUOROQUINOLONE ANTIBACTERIALS: SAR, MECHANISM OF ACTION, RESISTANCE, AND CLINICAL ASPECTS.MEDICINAL RESEARCH REVIEWS. VOL. 16. ISSUE 5. P. 433-486 71 33% 114
9 DA SILVA, AD , DE ALMEIDA, MV , DE SOUZA, MVN , COURI, MRC , (2003) BIOLOGICAL ACTIVITY AND SYNTHETIC METODOLOGIES FOR THE PREPARATION OF FLUOROQUINOLONES, A CLASS OF POTENT ANTIBACTERIAL AGENTS.CURRENT MEDICINAL CHEMISTRY. VOL. 10. ISSUE 1. P. 21-39 34 50% 55
10 HAYAKAWA, I , TAKEMURA, M , KIMURA, Y , (1994) RECENT PROGRESS IN THE STUDIES OF QUINOLONE ANTIBACTERIALS.JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN. VOL. 52. ISSUE 2. P. 92 -102 33 65% 1

Classes with closest relation at Level 1


Rank Class id link
1 33510 PRULIFLOXACIN//RUFLOXACIN//ULIFLOXACIN
2 27262 OXAZOLOQUINOLONES//PYRIDOQUINOXALINES//GOULD JACOBS REACTION
3 13319 INTERACTION WITH CALF THYMUS DNA//NORFLOXACIN//AGR FOOD TECHNOL NUTR
4 18332 1 8 NAPHTHYRIDINE//1 2 4TRIAZOLO4 3 A1 8NAPHTHYRIDINES//UNIV ARTS SCI
5 24385 MANAGEMENT HLTH NPMC//CIPROFLOXACIN//CYST FIBROSIS PULM CLIN TREATMENT
6 23431 2 AMINOCHALCONES//PHYSYNOR//PROD NAT ORIGINE VEGETALE SYNTH ORGAN
7 1143 JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY//ANTIMICROBIAL AGENTS AND CHEMOTHERAPY//FLEROXACIN
8 31577 PROLINE 3 HYDROXYLASE//PROLINE 4 HYDROXYLASE//ALPHA KETOGLUTARATE DEPENDENT IRONII OXYGENASES
9 17671 PHOTOTOXICITY//PHOTOGENOTOXICITY//FLUOROQUINOLONES
10 6168 DNA GYRASE//GYRASE//REVERSE GYRASE

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