Class information for:
Level 1: ENFUVIRTIDE//GP41//FUSION INHIBITOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
10596 1050 42.7 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
29 3       HIV//VIROLOGY//HIV 1 108954
10 2             AIDS RESEARCH AND HUMAN RETROVIRUSES//VIROLOGY//HIV 1 39664
10596 1                   ENFUVIRTIDE//GP41//FUSION INHIBITOR 1050

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ENFUVIRTIDE authKW 1654355 8% 66% 86
2 GP41 authKW 1507577 12% 41% 128
3 FUSION INHIBITOR authKW 1491621 9% 56% 92
4 T 20 authKW 840394 3% 85% 34
5 LINDSLEY F KIMBALL address 393737 9% 15% 90
6 SIX HELIX BUNDLE authKW 377165 2% 62% 21
7 HIV 1 FUSION INHIBITOR authKW 351032 1% 93% 13
8 HIV FUSION INHIBITOR authKW 314047 2% 60% 18
9 ENTRY INHIBITOR authKW 184062 3% 19% 33
10 BMS 378806 authKW 174478 1% 100% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Virology 13056 27% 0% 283
2 Infectious Diseases 2805 16% 0% 167
3 Chemistry, Medicinal 1926 13% 0% 139
4 Biochemistry & Molecular Biology 1384 32% 0% 341
5 Pharmacology & Pharmacy 747 18% 0% 185
6 Immunology 501 12% 0% 127
7 Microbiology 314 9% 0% 90
8 Biophysics 299 7% 0% 75
9 Chemistry, Organic 162 7% 0% 76
10 Cell Biology 54 6% 0% 61

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LINDSLEY F KIMBALL 393737 9% 15% 90
2 LINDSEY F KIMBALL 116319 0% 100% 4
3 TROP DIS CONTROL MOE 87239 0% 100% 3
4 MOL MODELING DRUG DESIGN 60567 1% 21% 10
5 BIOMODULATORS DRUGS 58159 0% 100% 2
6 EDASA SCI 58159 0% 100% 2
7 HUMAN VIROLMINIST EDUC 58159 0% 100% 2
8 UAB HIV OUTPATIENT CLIN 58159 0% 100% 2
9 VIRUS CONTROL 41525 1% 14% 10
10 ABD SEROTEC 38772 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AIDS RESEARCH AND HUMAN RETROVIRUSES 7003 3% 1% 36
2 JOURNAL OF VIROLOGY 5723 8% 0% 89
3 HIV CLINICAL TRIALS 3612 1% 2% 8
4 RETROVIROLOGY 3423 1% 1% 12
5 AIDS 3202 3% 0% 31
6 CHEMMEDCHEM 2123 1% 1% 13
7 ANTIVIRAL THERAPY 1860 1% 1% 11
8 JANAC-JOURNAL OF THE ASSOCIATION OF NURSES IN AIDS CARE 1624 1% 1% 6
9 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 1370 3% 0% 34
10 BIOORGANIC & MEDICINAL CHEMISTRY 1148 2% 0% 23

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ENFUVIRTIDE 1654355 8% 66% 86 Search ENFUVIRTIDE Search ENFUVIRTIDE
2 GP41 1507577 12% 41% 128 Search GP41 Search GP41
3 FUSION INHIBITOR 1491621 9% 56% 92 Search FUSION+INHIBITOR Search FUSION+INHIBITOR
4 T 20 840394 3% 85% 34 Search T+20 Search T+20
5 SIX HELIX BUNDLE 377165 2% 62% 21 Search SIX+HELIX+BUNDLE Search SIX+HELIX+BUNDLE
6 HIV 1 FUSION INHIBITOR 351032 1% 93% 13 Search HIV+1+FUSION+INHIBITOR Search HIV+1+FUSION+INHIBITOR
7 HIV FUSION INHIBITOR 314047 2% 60% 18 Search HIV+FUSION+INHIBITOR Search HIV+FUSION+INHIBITOR
8 ENTRY INHIBITOR 184062 3% 19% 33 Search ENTRY+INHIBITOR Search ENTRY+INHIBITOR
9 BMS 378806 174478 1% 100% 6 Search BMS+378806 Search BMS+378806
10 HIV ENTRY INHIBITOR 155087 1% 67% 8 Search HIV+ENTRY+INHIBITOR Search HIV+ENTRY+INHIBITOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LU, K , ASYIFAH, MR , SHAO, F , ZHANG, D , (2014) DEVELOPMENT OF HIV-1 FUSION INHIBITORS TARGETING GP41.CURRENT MEDICINAL CHEMISTRY. VOL. 21. ISSUE 17. P. 1976 -1996 139 67% 4
2 HE, YX , (2013) SYNTHESIZED PEPTIDE INHIBITORS OF HIV-1 GP41-DEPENDENT MEMBRANE FUSION.CURRENT PHARMACEUTICAL DESIGN. VOL. 19. ISSUE 10. P. 1800-1809 94 93% 14
3 BERKHOUT, B , EGGINK, D , SANDERS, RW , (2012) IS THERE A FUTURE FOR ANTIVIRAL FUSION INHIBITORS?.CURRENT OPINION IN VIROLOGY. VOL. 2. ISSUE 1. P. 50 -59 79 71% 37
4 EGGINK, D , BERKHOUT, B , SANDERS, RW , (2010) INHIBITION OF HIV-1 BY FUSION INHIBITORS.CURRENT PHARMACEUTICAL DESIGN. VOL. 16. ISSUE 33. P. 3716 -3728 100 61% 39
5 DE FEO, CJ , WEISS, CD , (2012) ESCAPE FROM HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) ENTRY INHIBITORS.VIRUSES-BASEL. VOL. 4. ISSUE 12. P. 3859-3911 143 42% 10
6 CAI, LF , JIANG, SB , (2010) DEVELOPMENT OF PEPTIDE AND SMALL-MOLECULE HIV-1 FUSION INHIBITORS THAT TARGET GP41.CHEMMEDCHEM. VOL. 5. ISSUE 11. P. 1813-1824 75 78% 38
7 PAN, CG , LIU, SW , JIANG, SB , (2010) HIV-1 GP41 FUSION INTERMEDIATE: A TARGET FOR HIV THERAPEUTICS.JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION. VOL. 109. ISSUE 2. P. 94-105 70 88% 21
8 YU, F , LU, L , DU, LY , ZHU, XJ , DEBNATH, AK , JIANG, SB , (2013) APPROACHES FOR IDENTIFICATION OF HIV-1 ENTRY INHIBITORS TARGETING GP41 POCKET.VIRUSES-BASEL. VOL. 5. ISSUE 1. P. 127 -149 70 80% 11
9 SU, Y , CHONG, HHU , QIU, ZL , XIONG, SW , HE, YX , (2015) MECHANISM OF HIV-1 RESISTANCE TO SHORT-PEPTIDE FUSION INHIBITORS TARGETING THE GP41 POCKET.JOURNAL OF VIROLOGY. VOL. 89. ISSUE 11. P. 5801 -5811 55 93% 2
10 TAN, JJ , MA, XT , LIU, C , ZHANG, XY , WANG, CX , (2013) THE CURRENT STATUS AND CHALLENGES IN THE DEVELOPMENT OF FUSION INHIBITORS AS THERAPEUTICS FOR HIV-1 INFECTION.CURRENT PHARMACEUTICAL DESIGN. VOL. 19. ISSUE 10. P. 1810-1817 66 81% 4

Classes with closest relation at Level 1


Rank Class id link
1 758 IAVI NEUTRALIZING ANTIBODY//DUKE HUMAN VACCINE//HIV AIDS VACCINE IMMUNOL IMMUNOGEN DISCOVER
2 772 CCR5//CCR5 ANTAGONIST//MARAVIROC
3 4519 FUSION PEPTIDE//MEMBRANE FUSION//TILTED PEPTIDE
4 28117 UF SIDA//P PHENOTYPE//UP A 6033
5 37210 SEVI//ULM PEPTIDE PHARMACEUT//BIOMOL SCI BURNETT BIOMED SCI
6 9263 HUMAN PARAINFLUENZA VIRUS//PORCINE RUBULAVIRUS//PARAMYXOVIRUS
7 1121 AIDS RESEARCH AND HUMAN RETROVIRUSES//V3 LOOP//GP120
8 22345 CYANOVIRIN N//GRIFFITHSIN//SCYTOVIRIN
9 3841 VIRUS CELL INTERACT SECT//GAG//HIV DRUG ISTANCE PROGRAM
10 24095 P15E//HIV 1 GP41//CKS 17

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