Class information for:
Level 1: TACRINE//METRIFONATE//TETRAHYDROAMINOACRIDINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
10092 1093 35.3 62%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
471 3       ACETYLCHOLINESTERASE//PARAOXONASE//SULFUR MUSTARD 23986
1440 2             ACETYLCHOLINESTERASE//BUTYRYLCHOLINESTERASE//TACRINE 7842
10092 1                   TACRINE//METRIFONATE//TETRAHYDROAMINOACRIDINE 1093

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TACRINE authKW 1474176 14% 33% 158
2 METRIFONATE authKW 537816 3% 51% 38
3 TETRAHYDROAMINOACRIDINE authKW 493180 3% 55% 32
4 NIK 247 authKW 205705 1% 82% 9
5 EPTASTIGMINE authKW 186231 1% 67% 10
6 PHYSOSTIGMINE authKW 148806 5% 10% 53
7 VELNACRINE authKW 137523 1% 62% 8
8 HEPTYLPHYSOSTIGMINE authKW 125707 1% 75% 6
9 CHOLINESTERASE INHIBITORS authKW 121037 6% 6% 67
10 METHOXYTACRINE authKW 89392 0% 80% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 5847 43% 0% 471
2 Psychiatry 2306 17% 0% 189
3 Clinical Neurology 1865 19% 0% 208
4 Neurosciences 1615 24% 0% 262
5 Geriatrics & Gerontology 933 5% 0% 57
6 Behavioral Sciences 291 4% 0% 45
7 Toxicology 243 5% 0% 57
8 Gerontology 162 2% 0% 19
9 Chemistry, Analytical 137 6% 0% 69
10 Chemistry, Medicinal 91 3% 0% 38

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACOL CLIN PHARMACOL DRUG TOXICOL 63849 0% 57% 4
2 BAYER CNS 55871 0% 100% 2
3 SERV RETROCESS PHARM 55871 0% 100% 2
4 MED NEUROBIOL CELLULAR MOL 41900 0% 50% 3
5 AZ ST ELISABETH 27936 0% 100% 1
6 BEHAV PHARMACOL TOXCIOL 27936 0% 100% 1
7 CANTHIA CLIN PHYSIOL 27936 0% 100% 1
8 CATTEDRA CHIM FARMACEUT 27936 0% 100% 1
9 CELLULAR MOL BIOL DRUG DESIGN DEV 27936 0% 100% 1
10 CENT PR PAULI 27936 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ALZHEIMER DISEASE & ASSOCIATED DISORDERS 13438 2% 2% 26
2 DEMENTIA 12498 1% 4% 11
3 ALZHEIMERS REPORTS 7438 1% 4% 6
4 HOMEOSTASIS IN HEALTH AND DISEASE 4549 1% 2% 7
5 PSYCHOPHARMACOLOGY BULLETIN 3970 1% 1% 16
6 JOURNAL OF NEURAL TRANSMISSION-PARKINSONS DISEASE AND DEMENTIA SECTION 3108 0% 2% 5
7 ACTA NEUROLOGICA SCANDINAVICA 2619 2% 0% 24
8 CNS DRUGS 1918 1% 1% 11
9 DRUG DEVELOPMENT RESEARCH 1835 1% 0% 14
10 JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS 1729 1% 0% 15

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TACRINE 1474176 14% 33% 158 Search TACRINE Search TACRINE
2 METRIFONATE 537816 3% 51% 38 Search METRIFONATE Search METRIFONATE
3 TETRAHYDROAMINOACRIDINE 493180 3% 55% 32 Search TETRAHYDROAMINOACRIDINE Search TETRAHYDROAMINOACRIDINE
4 NIK 247 205705 1% 82% 9 Search NIK+247 Search NIK+247
5 EPTASTIGMINE 186231 1% 67% 10 Search EPTASTIGMINE Search EPTASTIGMINE
6 PHYSOSTIGMINE 148806 5% 10% 53 Search PHYSOSTIGMINE Search PHYSOSTIGMINE
7 VELNACRINE 137523 1% 62% 8 Search VELNACRINE Search VELNACRINE
8 HEPTYLPHYSOSTIGMINE 125707 1% 75% 6 Search HEPTYLPHYSOSTIGMINE Search HEPTYLPHYSOSTIGMINE
9 CHOLINESTERASE INHIBITORS 121037 6% 6% 67 Search CHOLINESTERASE+INHIBITORS Search CHOLINESTERASE+INHIBITORS
10 METHOXYTACRINE 89392 0% 80% 4 Search METHOXYTACRINE Search METHOXYTACRINE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 WAGSTAFF, AJ , MCTAVISH, D , (1994) TACRINE - A REVIEW OF ITS PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES, AND THERAPEUTIC EFFICACY IN ALZHEIMERS-DISEASE.DRUGS & AGING. VOL. 4. ISSUE 6. P. 510-540 107 69% 103
2 SOARES, JC , GERSHON, S , (1995) THA - HISTORICAL ASPECTS, REVIEW OF PHARMACOLOGICAL PROPERTIES AND THERAPEUTIC EFFECTS.DEMENTIA. VOL. 6. ISSUE 4. P. 225-234 44 94% 29
3 SCHNEIDER, LS , (1993) CLINICAL-PHARMACOLOGY OF AMINOACRIDINES IN ALZHEIMERS-DISEASE.NEUROLOGY. VOL. 43. ISSUE 8. P. S64 -S79 47 84% 28
4 FREEMAN, SE , DAWSON, RM , (1991) TACRINE - A PHARMACOLOGICAL REVIEW.PROGRESS IN NEUROBIOLOGY. VOL. 36. ISSUE 4. P. 257-277 49 74% 139
5 BRAIDA, D , SALA, M , (2001) EPTASTIGMINE: TEN YEARS OF PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETIC, AND CLINICAL STUDIES.CNS DRUG REVIEWS. VOL. 7. ISSUE 4. P. 369-386 40 69% 18
6 MADDEN, S , SPALDIN, V , PARK, BK , (1995) CLINICAL PHARMACOKINETICS OF TACRINE.CLINICAL PHARMACOKINETICS. VOL. 28. ISSUE 6. P. 449-457 33 94% 33
7 ZHAO, B , MOOCHHALA, SM , THAM, SY , (2004) BIOLOGICALLY ACTIVE COMPONENTS OF PHYSOSTIGMA VENENOSUM.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 812. ISSUE 1-2. P. 183-192 29 81% 13
8 AHLIN, A , HASSAN, M , JUNTHE, T , NYBACK, H , (1994) TACRINE IN ALZHEIMERS-DISEASE - PHARMACOKINETIC AND CLINICAL COMPARISON OF ORAL AND RECTAL ADMINISTRATION.INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY. VOL. 9. ISSUE 4. P. 263-270 35 88% 4
9 ROBERTS, CJC , FORD, JM , TRUMAN, CA , SCOTT, M , MAKELA, PM , WILCOCK, GK , (1998) ASSESSMENT OF THE VALUE OF THERAPEUTIC MONITORING OF TACRINE IN ALZHEIMER'S DISEASE.EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. VOL. 54. ISSUE 9-10. P. 721 -724 29 91% 1
10 KUMAR, V , CALACHE, M , (1991) TREATMENT OF ALZHEIMERS-DISEASE WITH CHOLINERGIC DRUGS.INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS. VOL. 29. ISSUE 1. P. 23-37 37 82% 62

Classes with closest relation at Level 1


Rank Class id link
1 2910 DONEPEZIL//RIVASTIGMINE//GALANTAMINE
2 10229 ANIRACETAM//PIRACETAM//OXIRACETAM
3 11228 SOMATOSTATIN LIKE IMMUNOREACTIVITY//IRREGULAR ORIENTATION//MED BIOMED SCI NEUROSCI
4 2765 BUTYRYLCHOLINESTERASE//ACETYLCHOLINESTERASE//ACETYLCHOLINESTERASE INHIBITORS
5 2409 192 IGG SAPORIN//BASAL FOREBRAIN//NUCLEUS BASALIS MAGNOCELLULARIS
6 21950 FP TZTP//IQNP//N C 11METHYL 3 PIPERIDYL BENZILATE
7 35366 CIS DIAMMINEDIAQUAPLATINUM II//ACETYTCHOLINESTERASE//CIS DIAMMINEDIAQUAPLATINUM
8 27449 AMBENONIUM//BROMVALERYLUREA//9 HYDROXYPROPANTHELINE BROMIDE
9 20838 SEROTONIN MODULATED ANTICONSOLIDATION PROTEIN//UMR 7521LN2C//3 2 CARBOXYPIPERAZIN 4 YLPROPYL 1 PHOSPHONIC ACID
10 24854 2 SEC BUTYLPHENYL METHYLCARBAMATE BPMC//CENTRAL CHOLINERGIC SYSTEMS//CHOLINERGIC HYPERTENSION

Go to start page