The course comprises approximately 200 full-time study hours, whereof 14 hours of lectures and tutorials, 5 hours of laboratory work, 12 hours of seminars, in addition to self-studies.
FCK3116 Molecular Structure and Dynamics by NMR Spectroscopy in Solution State 7.5 credits
The course provides the basic principals of nuclear magnetic resonance spectroscopy (NMR) and interpretation of spectra for elucidating molecular structures and dynamics. The course contains lectures, tutorials and laboratory work. The tutorials supplement the lectures by solving problems with gradually increasing complexity.
Information for research students about course offerings
Next course offering is planned for the academic year 2023-2024
The course is given in cooperation with Treesearch’s national platform for research. For persons from industries associated to Treesearch the course cost is 5.000 SEK for one person, 9.000 SEK for two persons (4.500 SEK/person) and 12.000 SEK for three persons (4.000 SEK/person). For persons belonging to organizations not associated to Treesearch the cost is 21.300 SEK.
Choose semester and course offering to see current information and more about the course, such as course syllabus, study period, and application information.
Headings with content from the Course syllabus FCK3116 (Spring 2022–) are denoted with an asterisk ( )
Content and learning outcomes
Course disposition
Course contents
- Fundamental principles of NMR spectroscopy
- Spectral parameters (chemical shift, couplings)
- Relaxation, polarization transfer experiments, nuclear Overhauser effect (NOE)
- 2D-NMR spectroscopy
- Protocols for routine structural determination
- Dynamic NMR spectroscopy
Intended learning outcomes
Upon completion of the course the doctoral student should have the knowledge and ability to:
- describe the principles of NMR methods with regard to their advantages and limitations
- analyze NMR spectra, interpret and use the relationship between the spectral parameters and the molecular structure
- design strategies for analyzing and solving structural problems
- analyze and explain the effects of molecular dynamics, such as chemical exchange
Literature and preparations
Specific prerequisites
Eligible for studies at the third-cycle level.
Recommended prerequisites
Basic knowledge in organic chemistry.
Equipment
No information inserted
Literature
Online literature recommended by the lecturers.
Examination and completion
If the course is discontinued, students may request to be examined during the following two academic years.
Grading scale
P, F
Examination
- TEN1 - Home exam, 7.5 credits, grading scale: P, F
Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.
The examiner may apply another examination format when re-examining individual students.
Other requirements for final grade
To pass the course, the student must participate in at least 80% of the tutorials and 80% of the lectures. Participation in the laboratory practice and the oral presentation at the final seminar is mandatory.
Opportunity to complete the requirements via supplementary examination
No information inserted
Opportunity to raise an approved grade via renewed examination
No information inserted
Examiner
Ethical approach
- All members of a group are responsible for the group's work.
- In any assessment, every student shall honestly disclose any help received and sources used.
- In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.
Further information
Course room in Canvas
Registered students find further information about the implementation of the course in the course room in Canvas. A link to the course room can be found under the tab Studies in the Personal menu at the start of the course.
Offered by
Main field of study
This course does not belong to any Main field of study.
Education cycle
Third cycle
Add-on studies
No information inserted
Contact
Zoltan Szabo
Transitional regulations
If the examination form is changed, the student will be examined according to the examination form that applied when the student was admitted to the course. If the course is completed, the student is given the opportunity to be examined on the course for another two academic years.