Class information for:
Level 1: PLASMINOGEN ACTIVATOR INHIBITOR 1//PAI 1//FIBRINOLYSIS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
961 2936 38.5 80%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
111 3       THROMBOSIS RESEARCH//THROMBOSIS AND HAEMOSTASIS//HEMATOLOGY 71244
1157 2             FIBRINOLYSIS//PLASMINOGEN ACTIVATOR INHIBITOR 1//PAI 1 9477
961 1                   PLASMINOGEN ACTIVATOR INHIBITOR 1//PAI 1//FIBRINOLYSIS 2936

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PLASMINOGEN ACTIVATOR INHIBITOR 1 authKW 792422 10% 26% 290
2 PAI 1 authKW 642458 9% 25% 250
3 FIBRINOLYSIS journal 509751 6% 28% 178
4 PLASMINOGEN ACTIVATOR INHIBITOR authKW 331109 5% 24% 135
5 PHARMACEUT BIOL PHYTOPHARMACOL address 252143 2% 51% 48
6 PLASMINOGEN ACTIVATOR INHIBITOR TYPE 1 authKW 232335 2% 32% 69
7 4G 5G POLYMORPHISM authKW 199376 1% 91% 21
8 TISSUE TYPE PLASMINOGEN ACTIVATOR authKW 137798 3% 14% 94
9 PAI 1 INHIBITOR authKW 125523 0% 93% 13
10 THROMBOSIS AND HAEMOSTASIS journal 105558 11% 3% 318

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Hematology 59887 43% 0% 1276
2 Peripheral Vascular Diseases 38957 34% 0% 995
3 Cardiac & Cardiovascular System 1952 11% 0% 330
4 Medicine, Research & Experimental 761 7% 0% 209
5 Endocrinology & Metabolism 630 7% 0% 201
6 Biochemistry & Molecular Biology 594 16% 0% 472
7 Medicine, General & Internal 113 5% 0% 137
8 Biophysics 72 3% 0% 87
9 Medical Laboratory Technology 46 1% 0% 27
10 Cell Biology 41 4% 0% 122

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACEUT BIOL PHYTOPHARMACOL 252143 2% 51% 48
2 CELLULAR PROT SCI 97043 0% 67% 14
3 CLIN CHEM BLOOD COAGULAT 56597 0% 39% 14
4 EPI 9936 46790 0% 75% 6
5 DEMOG STAT STUDIES 27727 0% 67% 4
6 HUMAN SERV MANAGEMENT PUBL ADM 20797 0% 100% 2
7 ISOTOPE PHARM 20797 0% 100% 2
8 SERV BIOCHIM HORMONAL 20797 0% 100% 2
9 CLIN EXPT 18621 1% 7% 27
10 CELLULAR PROTEIN SCI 15595 0% 50% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FIBRINOLYSIS 509751 6% 28% 178
2 THROMBOSIS AND HAEMOSTASIS 105558 11% 3% 318
3 FIBRINOLYSIS & PROTEOLYSIS 101412 2% 20% 49
4 THROMBOSIS RESEARCH 53172 8% 2% 229
5 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 12979 3% 1% 97
6 BLOOD COAGULATION & FIBRINOLYSIS 12884 2% 2% 64
7 ARTERIOSCLEROSIS AND THROMBOSIS 4930 1% 2% 20
8 JOURNAL OF THROMBOSIS AND HAEMOSTASIS 4622 1% 1% 42
9 HAEMOSTASIS 3672 1% 2% 21
10 CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS 3334 1% 1% 23

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PLASMINOGEN ACTIVATOR INHIBITOR 1 792422 10% 26% 290 Search PLASMINOGEN+ACTIVATOR+INHIBITOR+1 Search PLASMINOGEN+ACTIVATOR+INHIBITOR+1
2 PAI 1 642458 9% 25% 250 Search PAI+1 Search PAI+1
3 FIBRINOLYSIS 434700 14% 11% 398 Search FIBRINOLYSIS Search FIBRINOLYSIS
4 PLASMINOGEN ACTIVATOR INHIBITOR 331109 5% 24% 135 Search PLASMINOGEN+ACTIVATOR+INHIBITOR Search PLASMINOGEN+ACTIVATOR+INHIBITOR
5 PLASMINOGEN ACTIVATOR INHIBITOR TYPE 1 232335 2% 32% 69 Search PLASMINOGEN+ACTIVATOR+INHIBITOR+TYPE+1 Search PLASMINOGEN+ACTIVATOR+INHIBITOR+TYPE+1
6 4G 5G POLYMORPHISM 199376 1% 91% 21 Search 4G+5G+POLYMORPHISM Search 4G+5G+POLYMORPHISM
7 TISSUE TYPE PLASMINOGEN ACTIVATOR 137798 3% 14% 94 Search TISSUE+TYPE+PLASMINOGEN+ACTIVATOR Search TISSUE+TYPE+PLASMINOGEN+ACTIVATOR
8 PAI 1 INHIBITOR 125523 0% 93% 13 Search PAI+1+INHIBITOR Search PAI+1+INHIBITOR
9 PLASMINOGEN ACTIVATOR 86548 3% 8% 101 Search PLASMINOGEN+ACTIVATOR Search PLASMINOGEN+ACTIVATOR
10 TISSUE PLASMINOGEN ACTIVATOR 67220 3% 7% 99 Search TISSUE+PLASMINOGEN+ACTIVATOR Search TISSUE+PLASMINOGEN+ACTIVATOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 VAN DE CRAEN, B , DECLERCK, PJ , GILS, A , (2012) THE BIOCHEMISTRY, PHYSIOLOGY AND PATHOLOGICAL ROLES OF PAI-1 AND THE REQUIREMENTS FOR PAI-1 INHIBITION IN VIVO.THROMBOSIS RESEARCH. VOL. 130. ISSUE 4. P. 576-585 129 81% 31
2 GILS, A , DECLERCK, PJ , (2004) PLASMINOGEN ACTIVATOR INHIBITOR-1.CURRENT MEDICINAL CHEMISTRY. VOL. 11. ISSUE 17. P. 2323-2334 145 76% 36
3 GILS, A , DECLERCK, PJ , (2004) THE STRUCTURAL BASIS FOR THE PATHOPHYSIOLOGICAL RELEVANCE OF PAL-L IN CARDIOVASCULAR DISEASES AND THE DEVELOPMENT OF POTENTIAL PAL-L INHIBITORS.THROMBOSIS AND HAEMOSTASIS. VOL. 91. ISSUE 3. P. 425-437 133 76% 66
4 DECLERCK, PJ , GILS, A , (2013) THREE DECADES OF RESEARCH ON PLASMINOGEN ACTIVATOR INHIBITOR-1: A MULTIFACETED SERPIN.SEMINARS IN THROMBOSIS AND HEMOSTASIS. VOL. 39. ISSUE 4. P. 356-364 103 69% 33
5 HUBER, K , (2001) PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 (PART ONE): BASIC MECHANISMS, REGULATION, AND ROLE FOR THROMBOEMBOLIC DISEASE.JOURNAL OF THROMBOSIS AND THROMBOLYSIS. VOL. 11. ISSUE 3. P. 183 -193 118 71% 52
6 ROUCH, A , VANUCCI-BACQUE, C , BEDOS-BELVAL, F , BALTAS, M , (2015) SMALL MOLECULES INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1-AN OVERVIEW.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 92. ISSUE . P. 619 -636 64 79% 9
7 BARNARD, SA , PIETERS, M , DE LANGE, Z , (2016) THE CONTRIBUTION OF DIFFERENT ADIPOSE TISSUE DEPOTS TO PLASMA PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) LEVELS.BLOOD REVIEWS. VOL. 30. ISSUE 6. P. 421 -429 68 71% 2
8 DE TAEYE, B , GILS, A , DECLERCK, PJ , (2004) THE STORY OF THE SERPIN PLASMINOGEN ACTIVATOR INHIBITOR I: IS THERE ANY NEED FOR ANOTHER MUTANT?.THROMBOSIS AND HAEMOSTASIS. VOL. 92. ISSUE 5. P. 898-924 105 66% 18
9 KRISHNAMURTI, C , ALVING, BM , (1992) PLASMINOGEN-ACTIVATOR INHIBITOR TYPE-1 - BIOCHEMISTRY AND EVIDENCE FOR MODULATION OF FIBRINOLYSIS INVIVO.SEMINARS IN THROMBOSIS AND HEMOSTASIS. VOL. 18. ISSUE 1. P. 67-80 120 81% 60
10 CESARI, M , PAHOR, M , INCALZI, RA , (2010) PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1): A KEY FACTOR LINKING FIBRINOLYSIS AND AGE-RELATED SUBCLINICAL AND CLINICAL CONDITIONS.CARDIOVASCULAR THERAPEUTICS. VOL. 28. ISSUE 5. P. E72 -E91 113 43% 72

Classes with closest relation at Level 1


Rank Class id link
1 19715 VITRONECTIN//KERCKHOFF KLIN HAEMOSTASIS UNIT//BIOL BUNKYO KU
2 17825 INTERNAL MED THER EUTCLIN MED//24 H PLATELET ACTIVITY//AB INITIO SCF DFT
3 27184 ALPHA2 ANTIPLASMIN//CLIN PATHOL BIOCHEM//NC100692
4 18741 ATHLETIC HORSE//B TG//FISIOL COMPARATA ESERCIZIO FIS
5 4791 FIBRINOGEN//FACTOR VII//FIBRINOGEN ASSAYS
6 16953 PLASMINOGEN ACTIVATOR INHIBITOR TYPE 2//PAI 2//SERPINB2
7 2760 FIBRINOLYSIS//BM 06022//T PA VARIANTS
8 23907 CROSS LINKED FIBRIN//NEPHROL A//AKT PHOSHPHORYLATION
9 21510 ADMINISTRATION BY INHALATION//SPECIALTY CARE SERV//TEXAS LUNG INJURY
10 458 UROKINASE RECEPTOR//UPAR//UPA

Go to start page