Class information for:
Level 1: KCC2//NKCC1//CHLORIDE HOMEOSTASIS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9441 1155 54.9 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
143 3       EPILEPSY//EPILEPSIA//EPILEPSY & BEHAVIOR 64226
984 2             KINDLING//EPILEPSY RESEARCH//KCC2 10569
9441 1                   KCC2//NKCC1//CHLORIDE HOMEOSTASIS 1155

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 KCC2 authKW 2624129 12% 69% 143
2 NKCC1 authKW 1004179 7% 46% 82
3 CHLORIDE HOMEOSTASIS authKW 639732 3% 73% 33
4 CATION CHLORIDE COTRANSPORTER authKW 466702 3% 55% 32
5 U901 address 464105 5% 34% 52
6 INMED address 304242 3% 29% 40
7 BUMETANIDE authKW 268022 5% 16% 62
8 MYOCLONIC TWITCHING authKW 237918 1% 75% 12
9 CHLORIDE COTRANSPORTER authKW 223375 1% 65% 13
10 INTRACELLULAR CHLORIDE authKW 190317 2% 40% 18

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 20318 75% 0% 871
2 Physiology 2013 15% 0% 174
3 Developmental Biology 394 4% 0% 47
4 Clinical Neurology 339 9% 0% 103
5 Cell Biology 38 5% 0% 59
6 Anesthesiology 35 1% 0% 16
7 Pharmacology & Pharmacy 28 6% 0% 66
8 Behavioral Sciences 7 1% 0% 12
9 Medicine, Research & Experimental 4 2% 0% 23
10 Anatomy & Morphology 4 0% 0% 5

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 U901 464105 5% 34% 52
2 INMED 304242 3% 29% 40
3 U29 156424 3% 18% 32
4 PROGRAM BEHAV COGNIT NEUROSCI 146900 1% 33% 17
5 NEUROBIOL MEDITERRANEE 90210 1% 21% 16
6 NEUROCHLORE 84593 0% 80% 4
7 UMR AIX MARSEILLE 2 S901 64759 1% 35% 7
8 INMED U29 59479 0% 75% 3
9 INSERM U901 55069 0% 42% 5
10 INSERM URM 1106 52872 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FRONTIERS IN CELLULAR NEUROSCIENCE 15748 3% 2% 31
2 JOURNAL OF NEUROSCIENCE 14001 12% 0% 134
3 JOURNAL OF NEUROPHYSIOLOGY 8450 6% 0% 74
4 EUROPEAN JOURNAL OF NEUROSCIENCE 6424 5% 0% 52
5 DEVELOPMENTAL NEUROBIOLOGY 4667 1% 1% 13
6 JOURNAL OF PHYSIOLOGY-LONDON 3990 5% 0% 53
7 BRAIN CELL BIOLOGY 3017 0% 6% 2
8 EPILEPSIA 2452 3% 0% 29
9 NEURAL PLASTICITY 2053 1% 1% 8
10 NEURON 1986 2% 0% 25

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 KCC2 2624129 12% 69% 143 Search KCC2 Search KCC2
2 NKCC1 1004179 7% 46% 82 Search NKCC1 Search NKCC1
3 CHLORIDE HOMEOSTASIS 639732 3% 73% 33 Search CHLORIDE+HOMEOSTASIS Search CHLORIDE+HOMEOSTASIS
4 CATION CHLORIDE COTRANSPORTER 466702 3% 55% 32 Search CATION+CHLORIDE+COTRANSPORTER Search CATION+CHLORIDE+COTRANSPORTER
5 BUMETANIDE 268022 5% 16% 62 Search BUMETANIDE Search BUMETANIDE
6 MYOCLONIC TWITCHING 237918 1% 75% 12 Search MYOCLONIC+TWITCHING Search MYOCLONIC+TWITCHING
7 CHLORIDE COTRANSPORTER 223375 1% 65% 13 Search CHLORIDE+COTRANSPORTER Search CHLORIDE+COTRANSPORTER
8 INTRACELLULAR CHLORIDE 190317 2% 40% 18 Search INTRACELLULAR+CHLORIDE Search INTRACELLULAR+CHLORIDE
9 POTASSIUM CHLORIDE COTRANSPORTER 130140 1% 62% 8 Search POTASSIUM+CHLORIDE+COTRANSPORTER Search POTASSIUM+CHLORIDE+COTRANSPORTER
10 GIANT DEPOLARIZING POTENTIALS 129532 1% 70% 7 Search GIANT+DEPOLARIZING+POTENTIALS Search GIANT+DEPOLARIZING+POTENTIALS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KAILA, K , PRICE, TJ , PAYNE, JA , PUSKARJOV, M , VOIPIO, J , (2014) CATION-CHLORIDE COTRANSPORTERS IN NEURONAL DEVELOPMENT, PLASTICITY AND DISEASE.NATURE REVIEWS NEUROSCIENCE. VOL. 15. ISSUE 10. P. 637 -654 160 59% 82
2 MEDINA, I , FRIEDEL, P , RIVERA, C , KAHLE, KT , KOURDOUGLI, N , UVAROV, P , PELLEGRINO, C , (2014) CURRENT VIEW ON THE FUNCTIONAL REGULATION OF THE NEURONAL K+-CL- COTRANSPORTER KCC2.FRONTIERS IN CELLULAR NEUROSCIENCE. VOL. 8. ISSUE . P. - 135 69% 23
3 BLAESSE, P , AIRAKSINEN, MS , RIVERA, C , KAILA, K , (2009) CATION-CHLORIDE COTRANSPORTERS AND NEURONAL FUNCTION.NEURON. VOL. 61. ISSUE 6. P. 820-838 130 58% 304
4 BEN-ARI, Y , WOODIN, MA , SERNAGOR, E , CANCEDDA, L , VINAY, L , RIVERA, C , LEGENDRE, P , LUHMANN, H , BORDEY, A , WENNER, P , ET AL (2012) REFUTING THE CHALLENGES OF THE DEVELOPMENTAL SHIFT OF POLARITY OF GABA ACTIONS: GABA MORE EXCITING THAN EVER!.FRONTIERS IN CELLULAR NEUROSCIENCE. VOL. 6. ISSUE . P. - 106 68% 34
5 BEN-ARI, Y , KHALILOV, I , KAHLE, KT , CHERUBINI, E , (2012) THE GABA EXCITATORY/INHIBITORY SHIFT IN BRAIN MATURATION AND NEUROLOGICAL DISORDERS.NEUROSCIENTIST. VOL. 18. ISSUE 5. P. 467 -486 83 63% 114
6 BEN-ARI, Y , GAIARSA, JL , TYZIO, R , KHAZIPOV, R , (2007) GABA: A PIONEER TRANSMITTER THAT EXCITES IMMATURE NEURONS AND GENERATES PRIMITIVE OSCILLATIONS.PHYSIOLOGICAL REVIEWS. VOL. 87. ISSUE 4. P. 1215 -1284 166 27% 489
7 KHAZIPOV, R , VALEEVA, G , KHALILOV, I , (2015) DEPOLARIZING GABA AND DEVELOPMENTAL EPILEPSIES.CNS NEUROSCIENCE & THERAPEUTICS. VOL. 21. ISSUE 2. P. 83 -91 83 75% 4
8 WU, HJ , CHE, XR , TANG, JJ , MA, FQ , PAN, K , ZHAO, MF , SHAO, A , WU, Q , ZHANG, JM , HONG, Y , (2016) THE K+-CL- COTRANSPORTER KCC2 AND CHLORIDE HOMEOSTASIS: POTENTIAL THERAPEUTIC TARGET IN ACUTE CENTRAL NERVOUS SYSTEM INJURY.MOLECULAR NEUROBIOLOGY. VOL. 53. ISSUE 4. P. 2141 -2151 80 74% 1
9 BEN-ARI, Y , (2014) THE GABA EXCITATORY/INHIBITORY DEVELOPMENTAL SEQUENCE: A PERSONAL JOURNEY.NEUROSCIENCE. VOL. 279. ISSUE . P. 187 -219 97 54% 24
10 CHAMMA, I , CHEVY, Q , PONCER, JC , LEVI, S , (2012) ROLE OF THE NEURONAL K-CL CO-TRANSPORTER KCC2 IN INHIBITORY AND EXCITATORY NEUROTRANSMISSION.FRONTIERS IN CELLULAR NEUROSCIENCE. VOL. 6. ISSUE . P. - 91 62% 38

Classes with closest relation at Level 1


Rank Class id link
1 7677 K CL COTRANSPORT//POTASSIUM CHLORIDE COTRANSPORT//BUMETANIDE
2 9426 PAROXYSMAL DEPOLARIZATION SHIFT//SEIZURE LIKE EVENTS//INTERICTAL BURSTING
3 29218 CL PUMP//CL ATPASE//INTRACELLULAR CL CONCENTRATION
4 14086 INTRACELLULAR PH//SLC4A4//BICARBONATE METABOLISM
5 15955 MOTOR SEIZURES//EPILEPTIC AFTERDISCHARGES//IMMATURE BRAIN
6 19612 SUBPLATE//SUBPLATE NEURONS//WHITE MATTER NEURONS
7 806 GABAA RECEPTOR//TONIC INHIBITION//SECT BIOCHEM PSYCHIAT
8 35909 MEGAKARYOCYTE RAT//PRESYNAPTIC GABAA RECEPTORS//SYNAPTIC BOUTON PREPARATION
9 20863 GLUTAMIC ACID DECARBOXYLASE//GLUTAMATE DECARBOXYLASE//GABA SYNTHESIS
10 5603 GABAB RECEPTOR//BACLOFEN//GABAB

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