Class information for:
Level 1: COMET ASSAY//SINGLE CELL GEL ELECTROPHORESIS//JACVAM VALIDATION STUDY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
7517 1359 33.2 79%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
116 3       MUTATION RESEARCH//TOXICOLOGY//CARCINOGENESIS 70215
469 2             MUTATION RESEARCH//MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS//COMET ASSAY 15922
7517 1                   COMET ASSAY//SINGLE CELL GEL ELECTROPHORESIS//JACVAM VALIDATION STUDY 1359

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 COMET ASSAY authKW 2042935 42% 16% 576
2 SINGLE CELL GEL ELECTROPHORESIS authKW 781462 7% 37% 94
3 JACVAM VALIDATION STUDY authKW 247141 1% 100% 11
4 MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS journal 240205 14% 6% 188
5 DNA DAMAGE authKW 218060 23% 3% 311
6 ALKALINE COMET ASSAY authKW 205370 2% 29% 32
7 COMET FISH authKW 199833 1% 68% 13
8 ALKALINE SINGLE CELL GEL ELECTROPHORESIS authKW 187214 1% 56% 15
9 MICROGEL ELECTROPHORESIS authKW 124810 1% 56% 10
10 IN VIVO COMET ASSAY authKW 118186 1% 48% 11

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Toxicology 34995 48% 0% 649
2 Genetics & Heredity 11590 39% 0% 524
3 Biotechnology & Applied Microbiology 3719 23% 0% 312
4 Oncology 454 11% 0% 155
5 Environmental Sciences 271 9% 0% 117
6 Biology 191 4% 0% 55
7 Nutrition & Dietetics 85 3% 0% 37
8 Cell Biology 76 6% 0% 81
9 Radiology, Nuclear Medicine & Medical Imaging 72 4% 0% 56
10 Public, Environmental & Occupational Health 65 4% 0% 58

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RADIAT ENVIRONM BIOL 95772 1% 47% 9
2 KLIN EXPT ONKOL 67396 0% 50% 6
3 CLIN RADIOTHER Y RADIOL ONCOL 44935 0% 100% 2
4 MED BIOL GEN GENET 44935 0% 100% 2
5 REPROD ENDOCRINOL REPROD GENET 44935 0% 100% 2
6 MUTAGENESIS UNIT 35573 1% 11% 15
7 OTOLARYNGOL ONCOL 35098 0% 31% 5
8 DNA ABIL 29955 0% 67% 2
9 DEV TOXICOL SECT 28883 0% 43% 3
10 SEZ NUTR UMANA 28883 0% 43% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS 240205 14% 6% 188
2 MUTAGENESIS 99531 7% 4% 100
3 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 22103 5% 2% 62
4 ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 19928 3% 2% 45
5 MUTATION RESEARCH-DNA REPAIR 9015 1% 3% 14
6 MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH 8231 1% 2% 15
7 MUTATION RESEARCH-DNAGING GENETIC INSTABILITY AND AGING 5050 0% 8% 3
8 MUTATION RESEARCH-GENETIC TOXICOLOGY 3809 1% 2% 7
9 NEOPLASMA 3164 2% 1% 21
10 TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS 2906 1% 1% 10

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 COMET ASSAY 2042935 42% 16% 576 Search COMET+ASSAY Search COMET+ASSAY
2 SINGLE CELL GEL ELECTROPHORESIS 781462 7% 37% 94 Search SINGLE+CELL+GEL+ELECTROPHORESIS Search SINGLE+CELL+GEL+ELECTROPHORESIS
3 JACVAM VALIDATION STUDY 247141 1% 100% 11 Search JACVAM+VALIDATION+STUDY Search JACVAM+VALIDATION+STUDY
4 DNA DAMAGE 218060 23% 3% 311 Search DNA+DAMAGE Search DNA+DAMAGE
5 ALKALINE COMET ASSAY 205370 2% 29% 32 Search ALKALINE+COMET+ASSAY Search ALKALINE+COMET+ASSAY
6 COMET FISH 199833 1% 68% 13 Search COMET+FISH Search COMET+FISH
7 ALKALINE SINGLE CELL GEL ELECTROPHORESIS 187214 1% 56% 15 Search ALKALINE+SINGLE+CELL+GEL+ELECTROPHORESIS Search ALKALINE+SINGLE+CELL+GEL+ELECTROPHORESIS
8 MICROGEL ELECTROPHORESIS 124810 1% 56% 10 Search MICROGEL+ELECTROPHORESIS Search MICROGEL+ELECTROPHORESIS
9 IN VIVO COMET ASSAY 118186 1% 48% 11 Search IN+VIVO+COMET+ASSAY Search IN+VIVO+COMET+ASSAY
10 MINI ORGAN CULTURES 101100 0% 75% 6 Search MINI+ORGAN+CULTURES Search MINI+ORGAN+CULTURES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ROJAS, E , LOPEZ, MC , VALVERDE, M , (1999) SINGLE CELL GEL ELECTROPHORESIS ASSAY: METHODOLOGY AND APPLICATIONS.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 722. ISSUE 1-2. P. 225 -254 113 50% 337
2 TICE, RR , AGURELL, E , ANDERSON, D , BURLINSON, B , HARTMANN, A , KOBAYASHI, H , MIYAMAE, Y , ROJAS, E , RYU, JC , SASAKI, YF , (2000) SINGLE CELL GEL/COMET ASSAY: GUIDELINES FOR IN VITRO AND IN VIVO GENETIC TOXICOLOGY TESTING.ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. VOL. 35. ISSUE 3. P. 206 -221 35 73% 2503
3 AZQUETA, A , COLLINS, AR , (2013) THE ESSENTIAL COMET ASSAY: A COMPREHENSIVE GUIDE TO MEASURING DNA DAMAGE AND REPAIR.ARCHIVES OF TOXICOLOGY. VOL. 87. ISSUE 6. P. 949 -968 59 65% 74
4 COLLINS, A , KOPPEN, G , VALDIGLESIAS, V , DUSINSKA, M , KRUSZEWSKI, M , MOLLER, P , ROJAS, E , DHAWAN, A , BENZIE, I , COSKUN, E , ET AL (2014) THE COMET ASSAY AS A TOOL FOR HUMAN BIOMONITORING STUDIES: THE COMNET PROJECT.MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH. VOL. 759. ISSUE . P. 27 -39 79 49% 41
5 OLIVE, PL , BANATH, JP , (2006) THE COMET ASSAY: A METHOD TO MEASURE DNA DAMAGE IN INDIVIDUAL CELLS.NATURE PROTOCOLS. VOL. 1. ISSUE 1. P. 23 -29 32 86% 509
6 DUSINSKA, M , COLLINS, AR , (2008) THE COMET ASSAY IN HUMAN BIOMONITORING: GENE-ENVIRONMENT INTERACTIONS.MUTAGENESIS. VOL. 23. ISSUE 3. P. 191 -205 66 52% 127
7 ANDERSON, D , YU, TW , MCGREGOR, DB , (1998) COMET ASSAY RESPONSES AS INDICATORS OF CARCINOGEN EXPOSURE.MUTAGENESIS. VOL. 13. ISSUE 6. P. 539 -555 103 48% 121
8 LANIER, C , MANIER, N , CUNY, D , DERAM, A , (2015) THE COMET ASSAY IN HIGHER TERRESTRIAL PLANT MODEL: REVIEW AND EVOLUTIONARY TRENDS.ENVIRONMENTAL POLLUTION. VOL. 207. ISSUE . P. 6 -20 65 45% 4
9 COLLINS, AR , (2004) THE COMET ASSAY FOR DNA DAMAGE AND REPAIR - PRINCIPLES, APPLICATIONS, AND LIMITATIONS.MOLECULAR BIOTECHNOLOGY. VOL. 26. ISSUE 3. P. 249-261 22 85% 1105
10 MOLLER, P , (2006) ASSESSMENT OF REFERENCE VALUES FOR DNA DAMAGE DETECTED BY THE COMET ASSAY IN HUMAN BLOOD CELL DNA.MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH. VOL. 612. ISSUE 2. P. 84 -104 66 48% 86

Classes with closest relation at Level 1


Rank Class id link
1 10689 NUCLEAR ABNORMALITIES//COMET ASSAY//GENOTOXICITY
2 22280 G2 ASSAY//MUTAGEN SENSITIVITY//CHROMOSOMAL RADIOSENSITIVITY
3 14247 CATEDRA CITOL//N NITROSOCARBOFURAN//AZZURRO
4 8957 8 HYDROXY 2 DEOXYGUANOSINE//8 OXODG//8 HYDROXYDEOXYGUANOSINE
5 21702 GREENSCREEN HC//MISLEADING POSITIVE RESULTS//VIRACEPT
6 3410 MICRONUCLEI//MUTAGENESIS//MICRONUCLEUS
7 24817 UNIT ANALYT TOXICOL MINERAL METAB//GENET BREEDING SEED PROD//25 DIMERCAPTO 1 3 4 THIADIAZOLE
8 7496 INTERNATIONAL JOURNAL OF RADIATION BIOLOGY//RADIATION RESEARCH//L5178Y MURINE LYMPHOMA SUBLINES
9 11300 LIVER MICRONUCLEUS ASSAY//MUTATION RESEARCH//MICRONUCLEUS TEST
10 25015 ADV AGING BRAIN//AMALAKI RASAYANA//DNA GAP REPAIR

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