Class information for:
Level 1: HOMOCYSTEINE//HYPERHOMOCYSTEINEMIA//FOLATE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
63 4660 38.7 84%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
502 3       HOMOCYSTEINE//FOLATE//FOLIC ACID 22046
254 2             HOMOCYSTEINE//FOLATE//FOLIC ACID 19695
63 1                   HOMOCYSTEINE//HYPERHOMOCYSTEINEMIA//FOLATE 4660

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 HOMOCYSTEINE authKW 5377632 49% 36% 2263
2 HYPERHOMOCYSTEINEMIA authKW 1112150 8% 45% 375
3 FOLATE authKW 360154 9% 13% 438
4 METHYLENETETRAHYDROFOLATE REDUCTASE authKW 329764 4% 27% 189
5 FOLIC ACID authKW 290411 8% 12% 386
6 HOMOCYSTEINE THIOLACTONE authKW 279529 1% 68% 63
7 HYPERHOMOCYSTEINAEMIA authKW 185018 1% 50% 56
8 VITAMIN B 12 authKW 159094 4% 12% 203
9 MTHFR authKW 137821 3% 15% 140
10 PLASMA HOMOCYSTEINE authKW 112988 1% 49% 35

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Peripheral Vascular Diseases 14948 17% 0% 796
2 Medical Laboratory Technology 9869 8% 0% 365
3 Nutrition & Dietetics 8621 12% 0% 551
4 Cardiac & Cardiovascular System 5222 14% 0% 660
5 Urology & Nephrology 2350 7% 0% 337
6 Hematology 2330 8% 0% 352
7 Medicine, General & Internal 1636 10% 0% 474
8 Medicine, Research & Experimental 1415 8% 0% 354
9 Endocrinology & Metabolism 1293 8% 0% 354
10 Transplantation 688 3% 0% 136

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INT PUBL HLTH 42836 1% 14% 46
2 LOCUS HOMOCYSTEINE RELATED VITAMINS 28659 0% 26% 17
3 VITAMIN BIOAVAI IL 26521 0% 45% 9
4 ARMAUER HANSEN HUS 23393 0% 71% 5
5 NEPHROL 1 19432 0% 21% 14
6 CARDIOVASC SCI GRP 19370 0% 20% 15
7 EA 3508 18285 0% 31% 9
8 GUANGDONG NEPHROL 18134 0% 46% 6
9 KLIN ABT NEPHROL DIALYSE 15703 0% 20% 12
10 STROKE PREVENT ATHEROSCLEROSIS 15655 0% 16% 15

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLINICAL CHEMISTRY AND LABORATORY MEDICINE 19479 2% 3% 112
2 ATHEROSCLEROSIS 13318 3% 1% 148
3 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 4813 2% 1% 75
4 NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES 3777 1% 2% 33
5 AMERICAN JOURNAL OF CLINICAL NUTRITION 3088 2% 1% 80
6 CLINICAL CHEMISTRY 2842 2% 1% 73
7 EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 2735 1% 1% 44
8 METABOLISM-CLINICAL AND EXPERIMENTAL 2563 1% 1% 60
9 THROMBOSIS RESEARCH 2433 1% 1% 63
10 JOURNAL OF NUTRITION 1991 1% 0% 65

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 HOMOCYSTEINE 5377632 49% 36% 2263 Search HOMOCYSTEINE Search HOMOCYSTEINE
2 HYPERHOMOCYSTEINEMIA 1112150 8% 45% 375 Search HYPERHOMOCYSTEINEMIA Search HYPERHOMOCYSTEINEMIA
3 FOLATE 360154 9% 13% 438 Search FOLATE Search FOLATE
4 METHYLENETETRAHYDROFOLATE REDUCTASE 329764 4% 27% 189 Search METHYLENETETRAHYDROFOLATE+REDUCTASE Search METHYLENETETRAHYDROFOLATE+REDUCTASE
5 FOLIC ACID 290411 8% 12% 386 Search FOLIC+ACID Search FOLIC+ACID
6 HOMOCYSTEINE THIOLACTONE 279529 1% 68% 63 Search HOMOCYSTEINE+THIOLACTONE Search HOMOCYSTEINE+THIOLACTONE
7 HYPERHOMOCYSTEINAEMIA 185018 1% 50% 56 Search HYPERHOMOCYSTEINAEMIA Search HYPERHOMOCYSTEINAEMIA
8 VITAMIN B 12 159094 4% 12% 203 Search VITAMIN+B+12 Search VITAMIN+B+12
9 MTHFR 137821 3% 15% 140 Search MTHFR Search MTHFR
10 PLASMA HOMOCYSTEINE 112988 1% 49% 35 Search PLASMA+HOMOCYSTEINE Search PLASMA+HOMOCYSTEINE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 REFSUM, H , UELAND, PM , NYGARD, O , VOLLSET, SE , (1998) HOMOCYSTEINE AND CARDIOVASCULAR DISEASE.ANNUAL REVIEW OF MEDICINE. VOL. 49. ISSUE . P. 31 -62 159 73% 1325
2 NYGARD, O , VOLLSET, SE , REFSUM, H , BRATTSTROM, L , UELAND, PM , (1999) TOTAL HOMOCYSTEINE AND CARDIOVASCULAR DISEASE.JOURNAL OF INTERNAL MEDICINE. VOL. 246. ISSUE 5. P. 425 -454 241 79% 172
3 DURAND, P , PROST, M , LOREAU, N , LUSSIER-CACAN, S , BLACHE, D , (2001) IMPAIRED HOMOCYSTEINE METABOLISM AND ATHEROTHROMBOTIC DISEASE.LABORATORY INVESTIGATION. VOL. 81. ISSUE 5. P. 645 -672 197 85% 140
4 WALD, DS , LAW, M , MORRIS, JK , (2002) HOMOCYSTEINE AND CARDIOVASCULAR DISEASE: EVIDENCE ON CAUSALITY FROM A META-ANALYSIS.BRITISH MEDICAL JOURNAL. VOL. 325. ISSUE 7374. P. 1202-1206K 97 78% 1096
5 BOUSHEY, CJ , BERESFORD, SAA , OMENN, GS , MOTULSKY, AG , (1995) A QUANTITATIVE ASSESSMENT OF PLASMA HOMOCYSTEINE AS A RISK FACTOR FOR VASCULAR-DISEASE - PROBABLE BENEFITS OF INCREASING FOLIC-ACID INTAKES.JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. VOL. 274. ISSUE 13. P. 1049-1057 63 85% 2703
6 MCKINLEY, MC , (2000) NUTRITIONAL ASPECTS AND POSSIBLE PATHOLOGICAL MECHANISMS OF HYPERHOMOCYSTEINAEMIA: AN INDEPENDENT RISK FACTOR FOR VASCULAR DISEASE.PROCEEDINGS OF THE NUTRITION SOCIETY. VOL. 59. ISSUE 2. P. 221 -237 168 83% 25
7 DE BREE, A , VERSCHUREN, WMM , KROMHOUT, D , KLUIJTMANS, LAJ , BLOM, HJ , (2002) HOMOCYSTEINE DETERMINANTS AND THE EVIDENCE TO WHAT EXTENT HOMOCYSTEINE DETERMINES THE RISK OF CORONARY HEART DISEASE.PHARMACOLOGICAL REVIEWS. VOL. 54. ISSUE 4. P. 599 -618 139 76% 171
8 WELCH, GN , LOSCALZO, J , (1998) HOMOCYSTEINE AND ATHEROTHROMBOSIS.NEW ENGLAND JOURNAL OF MEDICINE. VOL. 338. ISSUE 15. P. 1042 -1050 68 84% 1362
9 FONSECA, V , GUBA, SC , FINK, LM , (1999) HYPERHOMOCYSTEINEMIA AND THE ENDOCRINE SYSTEM: IMPLICATIONS FOR ATHEROSCLEROSIS AND THROMBOSIS.ENDOCRINE REVIEWS. VOL. 20. ISSUE 5. P. 738 -759 137 82% 79
10 REFSUM, H , SMITH, AD , UELAND, PM , NEXO, E , CLARKE, R , MCPARTLIN, J , JOHNSTON, C , ENGBAEK, F , SCHNEEDE, J , MCPARTLIN, C , ET AL (2004) FACTS AND RECOMMENDATIONS ABOUT TOTAL HOMOCYSTEINE DETERMINATIONS: AN EXPERT OPINION.CLINICAL CHEMISTRY. VOL. 50. ISSUE 1. P. 3 -32 125 50% 547

Classes with closest relation at Level 1


Rank Class id link
1 21832 HOMOCYSTINURIA//CYSTATHIONINE BETA SYNTHASE//CYSTATHIONINE BETA SYNTHASE DEFICIENCY
2 26698 S ADENOSYLHOMOCYSTEINE//W CHINA PRECLIN FORENS MED SCI//BASIC CARDIOCEREBRAL VASC DIS
3 27004 HOMOCYSTEINE//ABT KLIN CHEM MED ZENT OR//AFFILIATED JIANGSU SHENZE HOSP
4 6805 HOMOCYSTEINE//FOLATE//CELLULAR NEUROBIOL NEURODEGENERAT
5 3501 MTHFR//FOLATE//METHYLENETETRAHYDROFOLATE REDUCTASE
6 17681 FOLATE//L METHYLFOLATE//METHYLENETETRAHYDROFOLATE REDUCTASE GENE MTHFR
7 1292 NEURAL TUBE DEFECTS//FOLIC ACID//ANENCEPHALY
8 1766 VITAMIN B 12 DEFICIENCY//COBALAMIN//METHYLMALONIC ACID
9 25954 STAVANGER NEUROL UNIT//ADDUCTION LAG//AGE ACCELERATED ATHEROSCLEROSIS
10 2043 FACTOR V LEIDEN//THROMBOPHILIA//APC RESISTANCE

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