Class information for:
Level 1: LGR5//INTESTINAL STEM CELLS//LGR4

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6028 1541 47.2 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
27 3       DEVELOPMENTAL BIOLOGY//DEVELOPMENT//AGR2 109777
1844 2             TREFOIL FACTOR//CDX2//LGR5 6131
6028 1                   LGR5//INTESTINAL STEM CELLS//LGR4 1541

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LGR5 authKW 1242413 7% 58% 108
2 INTESTINAL STEM CELLS authKW 426085 4% 35% 61
3 LGR4 authKW 422685 2% 89% 24
4 CRYPT FISSION authKW 240149 1% 61% 20
5 R SPONDIN authKW 233085 1% 59% 20
6 ENTEROID authKW 186020 1% 72% 13
7 GPR48 authKW 160488 1% 90% 9
8 R SPONDIN2 authKW 158509 1% 100% 8
9 ORGANOID authKW 156026 2% 25% 31
10 DCLK1 authKW 133927 1% 52% 13

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 6418 34% 0% 518
2 Cell & Tissue Engineering 4105 5% 0% 75
3 Gastroenterology & Hepatology 3875 16% 0% 242
4 Developmental Biology 3076 9% 0% 143
5 Oncology 1662 19% 0% 286
6 CYTOLOGY & HISTOLOGY 1122 1% 0% 21
7 Biology 558 6% 0% 93
8 Biochemistry & Molecular Biology 490 19% 0% 289
9 Pathology 481 6% 0% 87
10 Anatomy & Morphology 429 2% 0% 38

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADV THER EUT GASTROINTESTINAL DIS 80900 0% 58% 7
2 ADV THER EUT GI DIS 79246 1% 50% 8
3 HUBRECHT 71849 4% 7% 55
4 ROYAL NETHERLANDS ARTS SCI KNAW 41272 0% 42% 5
5 ADV GI THER EUT 39627 0% 100% 2
6 CRC EPITHELIAL BIOL 39627 0% 100% 2
7 TCRG 39627 0% 100% 2
8 VEGETABLE CROP IMPROVEMENT 39627 0% 100% 2
9 GASTROINTESTINAL STEM CELL BIOL 29717 0% 50% 3
10 EPITHELIAL BIOL GRP 29131 0% 29% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL AND TISSUE KINETICS 14870 1% 4% 21
2 CELL STEM CELL 9499 1% 2% 22
3 CELL PROLIFERATION 6241 1% 2% 20
4 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 6088 3% 1% 44
5 GASTROENTEROLOGY 5511 4% 0% 61
6 STEM CELL REPORTS 4854 1% 2% 12
7 STEM CELLS 2402 1% 1% 23
8 DEVELOPMENT 1972 2% 0% 36
9 INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 1861 1% 0% 22
10 JOURNAL OF PATHOLOGY 1682 1% 0% 22

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LGR5 1242413 7% 58% 108 Search LGR5 Search LGR5
2 INTESTINAL STEM CELLS 426085 4% 35% 61 Search INTESTINAL+STEM+CELLS Search INTESTINAL+STEM+CELLS
3 LGR4 422685 2% 89% 24 Search LGR4 Search LGR4
4 CRYPT FISSION 240149 1% 61% 20 Search CRYPT+FISSION Search CRYPT+FISSION
5 R SPONDIN 233085 1% 59% 20 Search R+SPONDIN Search R+SPONDIN
6 ENTEROID 186020 1% 72% 13 Search ENTEROID Search ENTEROID
7 GPR48 160488 1% 90% 9 Search GPR48 Search GPR48
8 R SPONDIN2 158509 1% 100% 8 Search R+SPONDIN2 Search R+SPONDIN2
9 ORGANOID 156026 2% 25% 31 Search ORGANOID Search ORGANOID
10 DCLK1 133927 1% 52% 13 Search DCLK1 Search DCLK1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 BARKER, N , (2014) ADULT INTESTINAL STEM CELLS: CRITICAL DRIVERS OF EPITHELIAL HOMEOSTASIS AND REGENERATION.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 15. ISSUE 1. P. 19-33 91 81% 138
2 CLEVERS, H , (2013) THE INTESTINAL CRYPT, A PROTOTYPE STEM CELL COMPARTMENT.CELL. VOL. 154. ISSUE 2. P. 274-284 77 73% 164
3 HENNING, SJ , VON FURSTENBERG, RJ , (2016) GI STEM CELLS - NEW INSIGHTS INTO ROLES IN PHYSIOLOGY AND PATHOPHYSIOLOGY.JOURNAL OF PHYSIOLOGY-LONDON. VOL. 594. ISSUE 17. P. 4769 -4779 69 90% 1
4 POTTEN, CS , GANDARA, R , MAHIDA, YR , LOEFFLER, M , WRIGHT, NA , (2009) THE STEM CELLS OF SMALL INTESTINAL CRYPTS: WHERE ARE THEY?.CELL PROLIFERATION. VOL. 42. ISSUE 6. P. 731 -750 88 71% 89
5 SATO, T , CLEVERS, H , (2013) GROWING SELF-ORGANIZING MINI-GUTS FROM A SINGLE INTESTINAL STEM CELL: MECHANISM AND APPLICATIONS.SCIENCE. VOL. 340. ISSUE 6137. P. 1190-1194 42 84% 208
6 CARULLI, AJ , SAMUELSON, LC , SCHNELL, S , (2014) UNRAVELING INTESTINAL STEM CELL BEHAVIOR WITH MODELS OF CRYPT DYNAMICS.INTEGRATIVE BIOLOGY. VOL. 6. ISSUE 3. P. 243-257 71 77% 15
7 TAN, S , BARKER, N , (2015) EPITHELIAL STEM CELLS AND INTESTINAL CANCER.SEMINARS IN CANCER BIOLOGY. VOL. 32. ISSUE . P. 40 -53 87 65% 4
8 DE LAU, W , PENG, WC , GROS, P , CLEVERS, H , (2014) THE R-SPONDIN/LGR5/RNF43 MODULE: REGULATOR OF WNT SIGNAL STRENGTH.GENES & DEVELOPMENT. VOL. 28. ISSUE 4. P. 305-316 68 61% 63
9 BARKER, N , TAN, S , CLEVERS, H , (2013) LGR PROTEINS IN EPITHELIAL STEM CELL BIOLOGY.DEVELOPMENT. VOL. 140. ISSUE 12. P. 2484-2494 66 78% 29
10 GRACZ, AD , MAGNESS, ST , (2014) DEFINING HIERARCHIES OF STEMNESS IN THE INTESTINE: EVIDENCE FROM BIOMARKERS AND REGULATORY PATHWAYS.AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY. VOL. 307. ISSUE 3. P. G260 -G273 70 75% 10

Classes with closest relation at Level 1


Rank Class id link
1 27550 SPASMOLYTIC POLYPEPTIDE EXPRESSING METAPLASIA//NASHVILLE VA MED//GASTRIC STEM CELL
2 29848 MUSASHI//MUSASHI 1//MUSASHI 2
3 16185 APC//ADENOMATOUS POLYPOSIS COLI//MIN MOUSE
4 33865 IMMORTAL DNA//ADULT STEM CELL TECHNOL//IMMORTAL STRAND HYPOTHESIS
5 19363 PEPSINOGEN GENE//ECPG//PROVENTRICULAR GLAND
6 17256 CDX2//CDX1//CDX
7 30791 PUMA//PUMA GENE//P53 UPREGULATED MODULATOR OF APOPTOSIS PUMA
8 981 BETA CATENIN//AXIN//WNT
9 26550 CARP 1//ERRP//JOHN D DINGLE VA MED
10 18307 ABERRANT CRYPT FOCI//COLON CARCINOGENESIS//AZOXYMETHANE

Go to start page