Class information for:
Level 1: INTERLEUKIN 12//IL 12//IL 12 RECEPTOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5847 1568 42.7 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
10 3       IMMUNOLOGY//JOURNAL OF IMMUNOLOGY//IMMUNOL 134299
1321 2             INTERLEUKIN 12//CD23//INTERLEUKIN 4 8446
5847 1                   INTERLEUKIN 12//IL 12//IL 12 RECEPTOR 1568

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTERLEUKIN 12 authKW 1322035 19% 23% 301
2 IL 12 authKW 591805 14% 14% 221
3 IL 12 RECEPTOR authKW 166149 1% 53% 16
4 INTERLEUKIN 12 RECEPTOR authKW 94234 1% 44% 11
5 INFLAMMAT AUTOIMMUNE DIS address 82456 1% 35% 12
6 IL 12R BETA 2 authKW 77878 1% 40% 10
7 IL12B authKW 76513 1% 30% 13
8 IL 12P40 authKW 60559 1% 22% 14
9 INTERLEUKIN 12 IL 12 authKW 46377 1% 26% 9
10 BOVINE IL 12 authKW 43811 0% 75% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 16413 49% 0% 767
2 Oncology 2587 22% 0% 351
3 Medicine, Research & Experimental 2147 15% 0% 230
4 Cell Biology 882 14% 0% 217
5 Genetics & Heredity 725 10% 0% 160
6 Hematology 483 6% 0% 96
7 Biotechnology & Applied Microbiology 432 8% 0% 132
8 Biochemistry & Molecular Biology 197 14% 0% 217
9 Infectious Diseases 39 2% 0% 36
10 Allergy 33 1% 0% 14

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INFLAMMAT AUTOIMMUNE DIS 82456 1% 35% 12
2 MOL BIOL IMMUNOL MED GENET 42615 1% 24% 9
3 AIRC IMMUNOL TUMORS 37441 0% 38% 5
4 ONCOL C6 34613 0% 44% 4
5 MOL BIOL IMMUNOL GENET 30419 0% 31% 5
6 ANIM MODEL IL 25614 0% 26% 5
7 BIOL THER IES 21903 0% 38% 3
8 ALLERG M4211K 19472 0% 100% 1
9 ANIM PHYSIOL ECOTOXYCOL 19472 0% 100% 1
10 ANIM VIROLMINIST AGR VET PARASIT 19472 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER GENE THERAPY 17479 3% 2% 42
2 VETERINARY PRACTICE STAFF 15576 0% 40% 2
3 JOURNAL OF IMMUNOLOGY 10778 11% 0% 173
4 RESEARCH IN IMMUNOLOGY 7782 1% 2% 19
5 JOURNAL OF INTERFERON AND CYTOKINE RESEARCH 5815 2% 1% 26
6 HUMAN GENE THERAPY 4533 2% 1% 28
7 CYTOKINE 4466 2% 1% 32
8 EUROPEAN JOURNAL OF IMMUNOLOGY 4252 3% 0% 54
9 CHEMICAL IMMUNOLOGY 2593 0% 2% 7
10 JOURNAL OF IMMUNOTHERAPY 2578 1% 1% 15

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 INTERLEUKIN 12 1322035 19% 23% 301 Search INTERLEUKIN+12 Search INTERLEUKIN+12
2 IL 12 591805 14% 14% 221 Search IL+12 Search IL+12
3 IL 12 RECEPTOR 166149 1% 53% 16 Search IL+12+RECEPTOR Search IL+12+RECEPTOR
4 INTERLEUKIN 12 RECEPTOR 94234 1% 44% 11 Search INTERLEUKIN+12+RECEPTOR Search INTERLEUKIN+12+RECEPTOR
5 IL 12R BETA 2 77878 1% 40% 10 Search IL+12R+BETA+2 Search IL+12R+BETA+2
6 IL12B 76513 1% 30% 13 Search IL12B Search IL12B
7 IL 12P40 60559 1% 22% 14 Search IL+12P40 Search IL+12P40
8 INTERLEUKIN 12 IL 12 46377 1% 26% 9 Search INTERLEUKIN+12+IL+12 Search INTERLEUKIN+12+IL+12
9 BOVINE IL 12 43811 0% 75% 3 Search BOVINE+IL+12 Search BOVINE+IL+12
10 ANTITUMORAL VACCINATION 38945 0% 100% 2 Search ANTITUMORAL+VACCINATION Search ANTITUMORAL+VACCINATION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 TRINCHIERI, G , (1998) INTERLEUKIN-12: A CYTOKINE AT THE INTERFACE OF INFLAMMATION AND IMMUNITY.ADVANCES IN IMMUNOLOGY, VOL 70. VOL. 70. ISSUE . P. 83 -243 257 36% 595
2 TRINCHIERI, G , (1995) INTERLEUKIN-12 - A PROINFLAMMATORY CYTOKINE WITH IMMUNOREGULATORY FUNCTIONS THAT BRIDGE INNATE RESISTANCE AND ANTIGEN-SPECIFIC ADAPTIVE IMMUNITY.ANNUAL REVIEW OF IMMUNOLOGY. VOL. 13. ISSUE . P. 251-276 62 72% 1937
3 TUGUES, S , BURKHARD, SH , OHS, I , VROHLINGS, M , NUSSBAUM, K , BERG, JV , KULIG, P , BECHER, B , (2015) NEW INSIGHTS INTO IL-12-MEDIATED TUMOR SUPPRESSION.CELL DEATH AND DIFFERENTIATION. VOL. 22. ISSUE 2. P. 237 -246 88 57% 24
4 GATELY, MK , RENZETTI, LM , MAGRAM, J , STERN, AS , ADORINI, L , GUBLER, U , PRESKY, DH , (1998) THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: ROLE IN NORMAL AND PATHOLOGIC IMMUNE RESPONSES.ANNUAL REVIEW OF IMMUNOLOGY. VOL. 16. ISSUE . P. 495 -521 89 55% 924
5 LASEK, W , ZAGOZDZON, R , JAKOBISIAK, M , (2014) INTERLEUKIN 12: STILL A PROMISING CANDIDATE FOR TUMOR IMMUNOTHERAPY?.CANCER IMMUNOLOGY IMMUNOTHERAPY. VOL. 63. ISSUE 5. P. 419 -435 85 49% 39
6 TRINCHIERI, G , (2003) INTERLEUKIN-12 AND THE REGULATION OF INNATE RESISTANCE AND ADAPTIVE IMMUNITY.NATURE REVIEWS IMMUNOLOGY. VOL. 3. ISSUE 2. P. 133-146 59 43% 2078
7 TRINCHIERI, G , (1994) INTERLEUKIN-12 - A CYTOKINE PRODUCED BY ANTIGEN-PRESENTING CELLS WITH IMMUNOREGULATORY FUNCTIONS IN THE GENERATION OF T-HELPER CELLS TYPE-1 AND CYTOTOXIC LYMPHOCYTES.BLOOD. VOL. 84. ISSUE 12. P. 4008-4027 75 60% 874
8 HENDRZAK, JA , BRUNDA, MJ , (1995) BIOLOGY OF DISEASE - INTERLEUKIN-12 - BIOLOGIC ACTIVITY, THERAPEUTIC UTILITY, AND ROLE IN DISEASE.LABORATORY INVESTIGATION. VOL. 72. ISSUE 6. P. 619-637 110 61% 162
9 PORTIELJE, JEA , GRATAMA, JW , VAN OJIK, HH , STOTER, G , KRUIT, WHJ , (2003) IL-12: A PROMISING ADJUVANT FOR CANCER VACCINATION.CANCER IMMUNOLOGY IMMUNOTHERAPY. VOL. 52. ISSUE 3. P. 133-144 93 60% 69
10 WHITWORTH, JM , ALVAREZ, RD , (2011) EVALUATING THE ROLE OF IL-12 BASED THERAPIES IN OVARIAN CANCER: A REVIEW OF THE LITERATURE.EXPERT OPINION ON BIOLOGICAL THERAPY. VOL. 11. ISSUE 6. P. 751 -762 66 68% 6

Classes with closest relation at Level 1


Rank Class id link
1 16228 IL 27//INTERLEUKIN 27//IL 35
2 8124 TUMOR VACCINE//GENE THERAPY//B71
3 8274 INTERLEUKIN 4//IL 4//IGE SYNTHESIS
4 4871 INTERLEUKIN 18//IL 18//INTERLEUKIN 18 BINDING PROTEIN
5 10271 T BET//GATA 3//TBX21
6 33397 AK 5 TUMOR//AK 5 TUMOUR CELLS//ANTIBODY DAUNOMYCIN CONJUGATE
7 8997 INTERLEUKIN 10//IL 10//IL 10R1
8 643 DENDRITIC CELLS//IMMUNOTHERAPY//TUMOR LYSATE
9 28833 GENETIC RADIOTHERAPY//TNFERADE//CARG ELEMENTS
10 16780 CANC VACCINE DEV PROGRAM//CANC IMMUNOL IMMUNOTHER Y//TUMOR VACCINE GRP

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