Class information for:
Level 1: G QUADRUPLEX//QUADRUPLEX//G QUADRUPLEX DNA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
575 3287 49.6 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
183 3       APTAMER//G QUADRUPLEX//RIBOZYME 56307
2728 2             G QUADRUPLEX//QUADRUPLEX//G QUADRUPLEX DNA 3287
575 1                   G QUADRUPLEX//QUADRUPLEX//G QUADRUPLEX DNA 3287

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 G QUADRUPLEX authKW 3764772 20% 62% 658
2 QUADRUPLEX authKW 697553 3% 66% 113
3 G QUADRUPLEX DNA authKW 639062 3% 81% 85
4 I MOTIF authKW 454550 2% 74% 66
5 G QUARTET authKW 307137 2% 53% 63
6 CRUK BIOMOL STRUCT GRP address 276979 1% 76% 39
7 CANC UK BIOMOL STRUCT GRP address 235268 1% 67% 38
8 G QUADRUPLEX LIGANDS authKW 225690 1% 90% 27
9 ARNA address 217285 2% 38% 61
10 DNA QUADRUPLEX authKW 202527 1% 84% 26

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 10950 48% 0% 1590
2 Chemistry, Medicinal 3589 10% 0% 342
3 Chemistry, Multidisciplinary 3351 23% 0% 744
4 Biophysics 1773 9% 0% 308
5 Chemistry, Organic 880 9% 0% 294
6 Biochemical Research Methods 269 4% 0% 131
7 Chemistry, Analytical 226 5% 0% 168
8 Spectroscopy 65 2% 0% 63
9 Chemistry, Inorganic & Nuclear 64 3% 0% 89
10 Chemistry, Physical 52 6% 0% 204

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CRUK BIOMOL STRUCT GRP 276979 1% 76% 39
2 CANC UK BIOMOL STRUCT GRP 235268 1% 67% 38
3 ARNA 217285 2% 38% 61
4 U869 139281 2% 27% 56
5 PROTE STRUCT BIOL UNIT 132513 1% 42% 34
6 PHYS CHEM MASS SPE OMETRY 92326 0% 76% 13
7 IECB 89920 1% 22% 45
8 DIPARTIMENTO CHIM SOSTANZE NAT 86859 2% 13% 73
9 MINIST EDUC CHEM BIOL CHEM MOL ENGN 86678 0% 67% 14
10 RIMSTONE 74303 0% 100% 8

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NUCLEIC ACIDS RESEARCH 28066 11% 1% 347
2 BIOCHIMIE 6255 2% 1% 64
3 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 5721 2% 1% 54
4 BIOCHEMISTRY 4980 5% 0% 173
5 ORGANIC & BIOMOLECULAR CHEMISTRY 4476 2% 1% 76
6 CHEMICAL COMMUNICATIONS 4191 4% 0% 142
7 CHEMBIOCHEM 4154 1% 1% 45
8 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 3873 6% 0% 203
9 BIOPOLYMERS 3493 2% 1% 50
10 METHODS 3078 1% 1% 32

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 G QUADRUPLEX 3764772 20% 62% 658 Search G+QUADRUPLEX Search G+QUADRUPLEX
2 QUADRUPLEX 697553 3% 66% 113 Search QUADRUPLEX Search QUADRUPLEX
3 G QUADRUPLEX DNA 639062 3% 81% 85 Search G+QUADRUPLEX+DNA Search G+QUADRUPLEX+DNA
4 I MOTIF 454550 2% 74% 66 Search I+MOTIF Search I+MOTIF
5 G QUARTET 307137 2% 53% 63 Search G+QUARTET Search G+QUARTET
6 G QUADRUPLEX LIGANDS 225690 1% 90% 27 Search G+QUADRUPLEX+LIGANDS Search G+QUADRUPLEX+LIGANDS
7 DNA QUADRUPLEX 202527 1% 84% 26 Search DNA+QUADRUPLEX Search DNA+QUADRUPLEX
8 QUADRUPLEX DNA 185961 1% 69% 29 Search QUADRUPLEX+DNA Search QUADRUPLEX+DNA
9 TELOMERIC DNA 139456 1% 52% 29 Search TELOMERIC+DNA Search TELOMERIC+DNA
10 HUMAN TELOMERE 128948 1% 73% 19 Search HUMAN+TELOMERE Search HUMAN+TELOMERE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 NEIDLE, S , (2016) QUADRUPLEX NUCLEIC ACIDS AS NOVEL THERAPEUTIC TARGETS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 59. ISSUE 13. P. 5987 -6011 224 86% 15
2 DOLINNAYA, NG , OGLOBLINA, AM , YAKUBOVSKAYA, MG , (2016) STRUCTURE, PROPERTIES, AND BIOLOGICAL RELEVANCE OF THE DNA AND RNA G-QUADRUPLEXES: OVERVIEW 50 YEARS AFTER THEIR DISCOVERY.BIOCHEMISTRY-MOSCOW. VOL. 81. ISSUE 13. P. 1602 -1649 357 88% 0
3 MONCHAUD, D , TEULADE-FICHOU, MP , (2008) A HITCHHIKER'S GUIDE TO G-QUADRUPLEX LIGANDS.ORGANIC & BIOMOLECULAR CHEMISTRY. VOL. 6. ISSUE 4. P. 627 -636 177 92% 386
4 OHNMACHT, SA , NEIDLE, S , (2014) SMALL-MOLECULE QUADRUPLEX-TARGETED DRUG DISCOVERY.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. VOL. 24. ISSUE 12. P. 2602 -2612 172 92% 50
5 COLLIE, GW , PARKINSON, GN , (2011) THE APPLICATION OF DNA AND RNA G-QUADRUPLEXES TO THERAPEUTIC MEDICINES.CHEMICAL SOCIETY REVIEWS. VOL. 40. ISSUE 12. P. 5867 -5892 174 76% 229
6 LE, TVT , HAN, S , CHAE, J , PARK, HJ , (2012) G-QUADRUPLEX BINDING LIGANDS: FROM NATURALLY OCCURRING TO RATIONALLY DESIGNED MOLECULES.CURRENT PHARMACEUTICAL DESIGN. VOL. 18. ISSUE 14. P. 1948 -1972 200 87% 28
7 OU, TM , LU, YJ , TAN, JH , HUANG, ZS , WONG, KY , GU, LQ , (2008) G-QUADRUPLEXES: TARGETS IN ANTICANCER DRUG DESIGN.CHEMMEDCHEM. VOL. 3. ISSUE 5. P. 690-713 144 84% 274
8 KAUSHIK, M , KAUSHIK, S , BANSAL, A , SAXENA, S , KUKRETI, S , (2011) STRUCTURAL DIVERSITY AND SPECIFIC RECOGNITION OF FOUR STRANDED G-QUADRUPLEX DNA.CURRENT MOLECULAR MEDICINE. VOL. 11. ISSUE 9. P. 744 -769 204 77% 17
9 BALASUBRAMANIAN, S , HURLEY, LH , NEIDLE, S , (2011) TARGETING G-QUADRUPLEXES IN GENE PROMOTERS: A NOVEL ANTICANCER STRATEGY?.NATURE REVIEWS DRUG DISCOVERY. VOL. 10. ISSUE 4. P. 261 -275 100 75% 470
10 PATEL, DJ , PHAN, AT , KURYAVYI, V , (2007) HUMAN TELOMERE, ONCOGENIC PROMOTER AND 5'-UTR G-QUADRUPLEXES: DIVERSE HIGHER ORDER DNA AND RNA TARGETS FOR CANCER THERAPEUTICS.NUCLEIC ACIDS RESEARCH. VOL. 35. ISSUE 22. P. 7429-7455 153 66% 445

Classes with closest relation at Level 1


Rank Class id link
1 21785 ROSETTE NANOTUBES//NANOTECHNOL NINT NRC//REGENERAT MED W CHINA HOSPW CHINA MED SC
2 3100 TRIPLEX DNA//TRIPLEX//DNA TRIPLEX
3 1312 TELOMERE//TELOMERASE//TRF2
4 16834 SECT GENE STRUCT DIS//REPEAT INSTABILITY//MUTS BETA
5 14439 CATIONIC PORPHYRIN//OUTSIDE BINDING//AMIDINOPHENYLPORPHYRIN
6 217 TELOMERASE//HTERT//TELOMERASE ACTIVITY
7 4182 HYBRIDIZATION CHAIN REACTION//ROLLING CIRCLE AMPLIFICATION//DNAZYME
8 13926 BIOL MACROMOL STRUCT//SHEARED G CENTER DOT A PAIR//SHEARED A CENTER DOT C PAIR
9 21364 NUCLEOLIN//SURFACE NUCLEOLIN//AS1411
10 9916 NEWCAT//WOLFSON RAT STRUCT BASED DESIGN MOL DIAGNOST//CHEM BIOL PL CHEM

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