Class information for:
Level 1: CARCINOGENESIS//MEDIUM TERM BIOASSAY//FOCI OF ALTERED HEPATOCYTES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5237 1652 40.1 51%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
116 3       MUTATION RESEARCH//TOXICOLOGY//CARCINOGENESIS 70215
3033 2             CARCINOGENESIS//HEPATOCARCINOGENESIS//MEDIUM TERM BIOASSAY 2478
5237 1                   CARCINOGENESIS//MEDIUM TERM BIOASSAY//FOCI OF ALTERED HEPATOCYTES 1652

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARCINOGENESIS journal 193670 21% 3% 348
2 MEDIUM TERM BIOASSAY authKW 164386 1% 68% 13
3 FOCI OF ALTERED HEPATOCYTES authKW 159734 1% 79% 11
4 HEPATOCARCINOGENESIS authKW 127043 5% 9% 80
5 ENZYME ALTERED FOCI authKW 83161 1% 50% 9
6 TRANS 4 ACETYLAMINOSTILBENE authKW 73929 0% 100% 4
7 GST P POSITIVE FOCI authKW 71073 1% 38% 10
8 SEZ PATOL SPERIMENTALE ONCOL address 66531 0% 60% 6
9 DIETHYLNITROSAMINE authKW 59949 2% 10% 31
10 INITIATION ASSAY authKW 59141 0% 80% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 20609 57% 0% 947
2 Toxicology 6037 19% 0% 306
3 Pathology 2066 11% 0% 174
4 CYTOLOGY & HISTOLOGY 598 1% 0% 16
5 Gastroenterology & Hepatology 53 3% 0% 42
6 Medicine, Research & Experimental 28 3% 0% 46
7 Pharmacology & Pharmacy 20 5% 0% 81
8 Public, Environmental & Occupational Health 20 3% 0% 48
9 Biochemistry & Molecular Biology 18 8% 0% 132
10 Biophysics 12 2% 0% 36

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SEZ PATOL SPERIMENTALE ONCOL 66531 0% 60% 6
2 OCCUPAT TOXICOL GRP 41583 0% 75% 3
3 ABT CYTOPATHOL 0310 36964 0% 100% 2
4 BIOSTAT R0700 36964 0% 100% 2
5 UNITE BIOCHEM TOXICOL CANCEROL 36964 0% 100% 2
6 ABT KREBSFOR 24642 0% 67% 2
7 MED MCARDLE CANC 23759 0% 43% 3
8 BIOSTAT 2070 18482 0% 100% 1
9 CELL PATHOL 0310 18482 0% 100% 1
10 CYTOPATHOL ABT 0310 18482 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARCINOGENESIS 193670 21% 3% 348
2 CANCER LETTERS 22316 7% 1% 121
3 GANN 20780 2% 4% 29
4 TOXICOLOGIC PATHOLOGY 16691 3% 2% 48
5 JAPANESE JOURNAL OF CANCER RESEARCH 14043 3% 1% 52
6 CANCER RESEARCH 8258 8% 0% 133
7 VIRCHOWS ARCHIV B-CELL PATHOLOGY INCLUDING MOLECULAR PATHOLOGY 7130 1% 2% 22
8 TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS 4689 1% 2% 14
9 EKSPERIMENTALNAYA ONKOLOGIYA 3797 1% 1% 16
10 PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY/BK SERIES 3471 0% 5% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MEDIUM TERM BIOASSAY 164386 1% 68% 13 Search MEDIUM+TERM+BIOASSAY Search MEDIUM+TERM+BIOASSAY
2 FOCI OF ALTERED HEPATOCYTES 159734 1% 79% 11 Search FOCI+OF+ALTERED+HEPATOCYTES Search FOCI+OF+ALTERED+HEPATOCYTES
3 HEPATOCARCINOGENESIS 127043 5% 9% 80 Search HEPATOCARCINOGENESIS Search HEPATOCARCINOGENESIS
4 ENZYME ALTERED FOCI 83161 1% 50% 9 Search ENZYME+ALTERED+FOCI Search ENZYME+ALTERED+FOCI
5 TRANS 4 ACETYLAMINOSTILBENE 73929 0% 100% 4 Search TRANS+4+ACETYLAMINOSTILBENE Search TRANS+4+ACETYLAMINOSTILBENE
6 GST P POSITIVE FOCI 71073 1% 38% 10 Search GST+P+POSITIVE+FOCI Search GST+P+POSITIVE+FOCI
7 DIETHYLNITROSAMINE 59949 2% 10% 31 Search DIETHYLNITROSAMINE Search DIETHYLNITROSAMINE
8 INITIATION ASSAY 59141 0% 80% 4 Search INITIATION+ASSAY Search INITIATION+ASSAY
9 2 ACETYLAMINOFLUORENE 52921 1% 15% 19 Search 2+ACETYLAMINOFLUORENE Search 2+ACETYLAMINOFLUORENE
10 PRENEOPLASTIC HEPATOCYTES 49283 0% 67% 4 Search PRENEOPLASTIC+HEPATOCYTES Search PRENEOPLASTIC+HEPATOCYTES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 PITOT, HC , (1990) ALTERED HEPATIC FOCI - THEIR ROLE IN MURINE HEPATOCARCINOGENESIS.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. VOL. 30. ISSUE . P. 465-500 123 73% 158
2 ENZMANN, HG , BRUNNEMANN, KD , KAESTNER, B , IATROPOULOS, MJ , WILLIAMS, GM , (2014) DOSE-DEPENDENT INDUCTION OF PRENEOPLASTIC LESIONS BY THE TOBACCO-SPECIFIC NITROSAMINE CARCINOGEN NNK IN THE IN OVO CARCINOGENICITY ASSESSMENT (IOCA) ASSAY.EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY. VOL. 66. ISSUE 1. P. 35-40 29 83% 0
3 WHYSNER, J , ROSS, PM , WILLIAMS, GM , (1996) PHENOBARBITAL MECHANISTIC DATA AND RISK ASSESSMENT: ENZYME INDUCTION, ENHANCED CELL PROLIFERATION, AND TUMOR PROMOTION.PHARMACOLOGY & THERAPEUTICS. VOL. 71. ISSUE 1-2. P. 153 -191 69 47% 143
4 DRAGAN, YP , PITOT, HC , (1992) THE ROLE OF THE STAGES OF INITIATION AND PROMOTION IN PHENOTYPIC DIVERSITY DURING HEPATOCARCINOGENESIS IN THE RAT.CARCINOGENESIS. VOL. 13. ISSUE 5. P. 739-750 76 54% 63
5 LEE, GH , (2000) PARADOXICAL EFFECTS OF PHENOBARBITAL ON MOUSE HEPATOCARCINOGENESIS.TOXICOLOGIC PATHOLOGY. VOL. 28. ISSUE 2. P. 215 -225 38 83% 39
6 BANNASCH, P , (1986) PRENEOPLASTIC LESIONS AS END-POINTS IN CARCINOGENICITY TESTING .1. HEPATIC PRENEOPLASIA.CARCINOGENESIS. VOL. 7. ISSUE 5. P. 689-695 49 89% 149
7 FARBER, E , SARMA, DSR , (1987) HEPATOCARCINOGENESIS - A DYNAMIC CELLULAR PERSPECTIVE.LABORATORY INVESTIGATION. VOL. 56. ISSUE 1. P. 4-22 46 71% 364
8 MARONPOT, RR , (2009) BIOLOGICAL BASIS OF DIFFERENTIAL SUSCEPTIBILITY TO HEPATOCARCINOGENESIS AMONG MOUSE STRAINS.JOURNAL OF TOXICOLOGIC PATHOLOGY. VOL. 22. ISSUE 1. P. 11 -33 60 35% 15
9 MOORE, MA , KITAGAWA, T , (1986) HEPATOCARCINOGENESIS IN THE RAT - THE EFFECT OF PROMOTERS AND CARCINOGENS INVIVO AND INVITRO.INTERNATIONAL REVIEW OF CYTOLOGY-A SURVEY OF CELL BIOLOGY. VOL. 101. ISSUE . P. 125 -173 101 43% 120
10 DRAGAN, YP , HULLY, J , CROW, R , MASS, M , PITOT, HC , (1994) INCORPORATION OF BROMODEOXYURIDINE IN GLUTATHIONE S-TRANSFERASE-POSITIVE HEPATOCYTES DURING RAT MULTISTAGE HEPATOCARCINOGENESIS.CARCINOGENESIS. VOL. 15. ISSUE 9. P. 1939 -1947 44 71% 23

Classes with closest relation at Level 1


Rank Class id link
1 29510 MOVEMENT ACTIVITY//PIPERONYL BUTOXIDE//ENZYMATICALLY MODIFIED ISOQUERCITRIN
2 24089 PROLIFERATION CULTURED HEPATOCYTE//DUNN OSTEOSARCOMA CELLS//S 1 2 DICARBOXYETHYLGLUTATHIONE
3 32486 HUMAN GENET TOXICOL SECT GENET//17 HYDROXY 3 OXOPREGNA 4 6 DIENE DERIVATIVES//ABERRANT METAPHASE NUMBER
4 15938 GEORGE WHIPPLE CANC PATHOL//CHAWNSHANG CHANG LIVER CANC//ANAT STRUCT SCI
5 3761 PEROXISOME PROLIFERATOR//PEROXISOME PROLIFERATION//3 THIA FATTY ACIDS
6 18907 MODELS OF CARCINOGENESIS//MVK MODEL//CESSATION LAG
7 35373 HEPATIC FOCI//CHONGNRO GU//DIMETHYL PGE2
8 13432 BUTYLATED HYDROXYTOLUENE//BUTYLATED HYDROXYANISOLE//2 TERT BUTYL1 4HYDROQUINONE
9 26099 CHROMATIN SUPRAORGANIZATION//NUCLEAR PHENOTYPES//EXTENDED CHROMATIN FIBERS
10 13514 ORTHO PHENYLPHENOL//EVALUAT ENVIRONM IMPACT HUMAN HLTH TOXICAM//PHENYLHYDROQUINONE

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