Class information for:
Level 1: VLA 4//VLA 4 ANTAGONIST//ALPHA4BETA1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5002 1689 38.6 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
307 3       INTEGRIN//ALPORT SYNDROME//LAMININ 40384
821 2             SELECTINS//ADHESION MOLECULES//E SELECTIN 11922
5002 1                   VLA 4//VLA 4 ANTAGONIST//ALPHA4BETA1 1689

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 VLA 4 authKW 295346 3% 28% 59
2 VLA 4 ANTAGONIST authKW 257095 1% 89% 16
3 ALPHA4BETA1 authKW 133111 1% 82% 9
4 VCAM 1 authKW 111926 4% 9% 68
5 INFLAMMAT RHEUMATOL address 97610 1% 60% 9
6 CD49D CD29 authKW 72309 0% 100% 4
7 ADHESION MOLECULES authKW 67486 8% 3% 135
8 ALPHA 4 BETA 1 INTEGRIN authKW 62480 1% 31% 11
9 VERY LATE ANTIGEN 4 authKW 45745 1% 28% 9
10 ALPHA4 INTEGRINS authKW 41316 0% 57% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 13758 43% 0% 733
2 Transplantation 8007 15% 0% 246
3 Rheumatology 2039 7% 0% 111
4 Surgery 1076 15% 0% 259
5 Cell Biology 758 13% 0% 213
6 Chemistry, Medicinal 718 7% 0% 115
7 Pathology 461 5% 0% 90
8 Hematology 232 4% 0% 74
9 Medicine, Research & Experimental 222 5% 0% 92
10 Biochemistry & Molecular Biology 187 13% 0% 225

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INFLAMMAT RHEUMATOL 97610 1% 60% 9
2 DISCOVERY INFLAMMAT P DIS 24102 0% 67% 2
3 PEDIAT RHEUMATOL PROGRAM 24102 0% 67% 2
4 ROCHE 22321 1% 8% 15
5 1825 EASTCHESTER RD 18077 0% 100% 1
6 ABT INFEKTIOL KLIN IMMUNOL 18077 0% 100% 1
7 ABT VISZERAL TRANPLANTAT CHIRURG 18077 0% 100% 1
8 ALLERGY UNIT IMMUNOL ALLERGOL 18077 0% 100% 1
9 ASSAY DEV CPDS PROFILING 18077 0% 100% 1
10 BASIC CHEM ANALYT SCI 18077 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL ADHESION AND COMMUNICATION 29163 1% 8% 21
2 JOURNAL OF IMMUNOLOGY 7877 9% 0% 154
3 TRANSPLANTATION 6348 5% 0% 81
4 TRANSPLANTATION PROCEEDINGS 5731 7% 0% 114
5 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2758 4% 0% 63
6 SCANDINAVIAN JOURNAL OF IMMUNOLOGY 1974 1% 0% 25
7 SPRINGER SEMINARS IN IMMUNOPATHOLOGY 1940 1% 1% 9
8 IMMUNOLOGY 1809 2% 0% 30
9 CELLULAR IMMUNOLOGY 1645 2% 0% 27
10 ARTHRITIS AND RHEUMATISM 1643 2% 0% 31

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 VLA 4 295346 3% 28% 59 Search VLA+4 Search VLA+4
2 VLA 4 ANTAGONIST 257095 1% 89% 16 Search VLA+4+ANTAGONIST Search VLA+4+ANTAGONIST
3 ALPHA4BETA1 133111 1% 82% 9 Search ALPHA4BETA1 Search ALPHA4BETA1
4 VCAM 1 111926 4% 9% 68 Search VCAM+1 Search VCAM+1
5 CD49D CD29 72309 0% 100% 4 Search CD49D+CD29 Search CD49D+CD29
6 ADHESION MOLECULES 67486 8% 3% 135 Search ADHESION+MOLECULES Search ADHESION+MOLECULES
7 ALPHA 4 BETA 1 INTEGRIN 62480 1% 31% 11 Search ALPHA+4+BETA+1+INTEGRIN Search ALPHA+4+BETA+1+INTEGRIN
8 VERY LATE ANTIGEN 4 45745 1% 28% 9 Search VERY+LATE+ANTIGEN+4 Search VERY+LATE+ANTIGEN+4
9 ALPHA4 INTEGRINS 41316 0% 57% 4 Search ALPHA4+INTEGRINS Search ALPHA4+INTEGRINS
10 VLA 4 INTEGRIN 40672 0% 75% 3 Search VLA+4+INTEGRIN Search VLA+4+INTEGRIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 CARLOS, TM , HARLAN, JM , (1994) LEUKOCYTE-ENDOTHELIAL ADHESION MOLECULES.BLOOD. VOL. 84. ISSUE 7. P. 2068-2101 96 22% 2302
2 HUTT, OE , SAUBERN, S , WINKLER, DA , (2011) MODELING THE MOLECULAR BASIS FOR ALPHA 4 BETA 1 INTEGRIN ANTAGONISM.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 19. ISSUE 19. P. 5903 -5911 41 79% 4
3 BEHREND, M , (2000) IMMUNE-ADHESION MOLECULES IN THE PREVENTION OF ALLOGRAFT REJECTION AND REPERFUSION INJURY.EXPERT OPINION ON INVESTIGATIONAL DRUGS. VOL. 9. ISSUE 4. P. 789-805 65 68% 12
4 YANG, GX , HAGMANN, WK , (2003) VLA-4 ANTAGONISTS: POTENT INHIBITORS OF LYMPHOCYTE MIGRATION.MEDICINAL RESEARCH REVIEWS. VOL. 23. ISSUE 3. P. 369-392 59 59% 41
5 TILLEY, JW , (2008) VERY LATE ANTIGEN-4 INTEGRIN ANTAGONISTS.EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 18. ISSUE 8. P. 841 -859 52 53% 19
6 SZEKANECZ, Z , SZEGEDI, G , KOCH, AE , (1996) CELLULAR ADHESION MOLECULES IN RHEUMATOID ARTHRITIS: REGULATION BY CYTOKINES AND POSSIBLE CLINICAL IMPORTANCE.JOURNAL OF INVESTIGATIVE MEDICINE. VOL. 44. ISSUE 4. P. 124-135 71 49% 29
7 MOJCIK, CF , SHEVACH, EM , (1997) ADHESION MOLECULES - A RHEUMATOLOGIC PERSPECTIVE.ARTHRITIS AND RHEUMATISM. VOL. 40. ISSUE 6. P. 991-1004 71 47% 1
8 TILLEY, JW , (2002) VLA-4 ANTAGONISTS.EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 12. ISSUE 7. P. 991 -1008 53 51% 23
9 HAGMANN, WK , (2004) THE DISCOVERY AND POTENTIAL OF N-SULFONYLATED DIPEPTIDE VLA-4 ANTAGONISTS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 4. ISSUE 14. P. 1461-1471 30 83% 11
10 CARTER, RA , WICKS, IP , (2001) VASCULAR CELL ADHESION MOLECULE 1 (CD106) - A MULTIFACETED REGULATOR OF JOINT INFLAMMATION.ARTHRITIS AND RHEUMATISM. VOL. 44. ISSUE 5. P. 985-994 54 41% 66

Classes with closest relation at Level 1


Rank Class id link
1 12380 ICAM 1//INTERCELLULAR ADHESION MOLECULE 1//SICAM 1
2 10539 MADCAM 1//BETA 7 INTEGRIN//ALPHAEBETA7
3 5709 LFA 1//LEUKOCYTE ADHESION DEFICIENCY//TELENCEPHALIN
4 12201 E SELECTIN//ROYAL CITY DUBLIN HOSP EDUC//INTERCELLULAR ADHESION MOLECULE 1
5 1069 SELECTINS//L SELECTIN//PSGL 1
6 2335 INTEGRIN//INTEGRIN ALPHA 6 BETA 4//VLA 1
7 19364 SECT HUMAN TRANSLAT IMMUNOL//HEART ENDOTHELIAL CELLS//NON MHC
8 34019 ANGINEX//ENDOTOXIN NEUTRALIZING//TUMOR ANGIOGENESIS
9 21472 NEUTROPHIL MARGINATION//PULMONARY MICROCIRCULATION//BRONCHIAL TEMPERATURE
10 7566 GLOMERULONEPHRITIS//INFLAMMATORY DIS//NEPHROTOXIC NEPHRITIS

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