Class information for:
Level 1: RNASE L//2 5A//2 5 OLIGOADENYLATE SYNTHETASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4170 1834 35.2 58%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
210 3       IMMUNOLOGY//JOURNAL OF INTERFERON RESEARCH//NK CELLS 51916
1202 2             JOURNAL OF INTERFERON RESEARCH//INTERFERON//JOURNAL OF INTERFERON AND CYTOKINE RESEARCH 9220
4170 1                   RNASE L//2 5A//2 5 OLIGOADENYLATE SYNTHETASE 1834

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RNASE L authKW 515449 3% 61% 51
2 2 5A authKW 379250 1% 84% 27
3 2 5 OLIGOADENYLATE SYNTHETASE authKW 340475 2% 45% 45
4 JOURNAL OF INTERFERON RESEARCH journal 307943 7% 14% 134
5 SECT BIOMED CHEM address 289523 1% 87% 20
6 2 5 OLIGOADENYLATE authKW 266358 1% 80% 20
7 RIBONUCLEASE L authKW 175838 1% 81% 13
8 OLIGOADENYLATE SYNTHETASE authKW 127875 1% 59% 13
9 RNASE L INHIBITOR authKW 96856 0% 73% 8
10 2 5A SYNTHETASE authKW 83229 1% 50% 10

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Virology 9277 17% 0% 319
2 Biochemistry & Molecular Biology 6810 51% 0% 931
3 Cell Biology 1239 15% 0% 274
4 Biophysics 571 7% 0% 136
5 Immunology 296 8% 0% 145
6 Biology 192 4% 0% 66
7 Oncology 162 7% 0% 129
8 Medicine, Research & Experimental 113 4% 0% 76
9 Biotechnology & Applied Microbiology 91 5% 0% 83
10 CYTOLOGY & HISTOLOGY 46 0% 0% 5

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SECT BIOMED CHEM 289523 1% 87% 20
2 BENTH ECOL BIO ERS 49944 0% 100% 3
3 INTERFERONS SARCOLECTINE 38049 0% 57% 4
4 ADBEA 37456 0% 75% 3
5 ERS CNRS 572 33296 0% 100% 2
6 INTERFERONS SARCOLECTINE H440 33296 0% 100% 2
7 CLIN CHEM PROGRAM 24475 0% 29% 5
8 LERNER 22904 5% 2% 84
9 MOL BIOL NC20 20484 0% 31% 4
10 UNITE VIROL IMMUNOL CELLULAIRE 20382 0% 18% 7

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF INTERFERON RESEARCH 307943 7% 14% 134
2 TEXAS REPORTS ON BIOLOGY AND MEDICINE 26167 1% 10% 15
3 JOURNAL OF INTERFERON AND CYTOKINE RESEARCH 12391 2% 2% 41
4 UCLA SYMPOSIA ON MOLECULAR AND CELLULAR BIOLOGY 8718 0% 7% 8
5 VIROLOGY 6219 5% 0% 84
6 JOURNAL OF GENERAL VIROLOGY 4402 3% 0% 60
7 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 4073 2% 1% 34
8 MOLECULAR BIOTHERAPY 2293 0% 7% 2
9 ANNALES DE L INSTITUT PASTEUR-VIROLOGY 2265 0% 3% 5
10 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 1973 2% 0% 31

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 RNASE L 515449 3% 61% 51 Search RNASE+L Search RNASE+L
2 2 5A 379250 1% 84% 27 Search 2+5A Search 2+5A
3 2 5 OLIGOADENYLATE SYNTHETASE 340475 2% 45% 45 Search 2+5+OLIGOADENYLATE+SYNTHETASE Search 2+5+OLIGOADENYLATE+SYNTHETASE
4 2 5 OLIGOADENYLATE 266358 1% 80% 20 Search 2+5+OLIGOADENYLATE Search 2+5+OLIGOADENYLATE
5 RIBONUCLEASE L 175838 1% 81% 13 Search RIBONUCLEASE+L Search RIBONUCLEASE+L
6 OLIGOADENYLATE SYNTHETASE 127875 1% 59% 13 Search OLIGOADENYLATE+SYNTHETASE Search OLIGOADENYLATE+SYNTHETASE
7 RNASE L INHIBITOR 96856 0% 73% 8 Search RNASE+L+INHIBITOR Search RNASE+L+INHIBITOR
8 2 5A SYNTHETASE 83229 1% 50% 10 Search 2+5A+SYNTHETASE Search 2+5A+SYNTHETASE
9 2 5A SYSTEM 74912 0% 75% 6 Search 2+5A+SYSTEM Search 2+5A+SYSTEM
10 OAS1 66583 0% 50% 8 Search OAS1 Search OAS1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 PLAYER, MR , TORRENCE, PF , (1998) THE 2-5A SYSTEM: MODULATION OF VIRAL AND CELLULAR PROCESSES THROUGH ACCELERATION OF RNA DEGRADATION.PHARMACOLOGY & THERAPEUTICS. VOL. 78. ISSUE 2. P. 55 -113 307 74% 201
2 BISBAL, C , SILVERMAN, RH , (2007) DIVERSE FUNCTIONS OF RNASE L AND IMPLICATIONS IN PATHOLOGY.BIOCHIMIE. VOL. 89. ISSUE 6-7. P. 789 -798 86 69% 60
3 LUXEMBOURG, A , (1988) 2-5A, A MEDIATOR IN SEARCH OF A FUNCTION.BULLETIN DE L INSTITUT PASTEUR. VOL. 86. ISSUE 4. P. 373-417 159 86% 6
4 DRAPPIER, M , SORGELOOS, F , MICHIELS, T , (2014) THE OAS/RNASEL PATHWAY AND ITS INHIBITION BY VIRUSES.VIROLOGIE. VOL. 18. ISSUE 5. P. 264 -277 80 70% 0
5 HOVANESSIAN, AG , JUSTESEN, J , (2007) THE HUMAN 2 '-5 ' OLIGOADENYLATE SYNTHETASE FAMILY: UNIQUE INTERFERON-INDUCIBLE ENZYMES CATALYZING 2 '-5 ' INSTEAD OF 3 '-5 ' PHOSPHODIESTER BOND FORMATION.BIOCHIMIE. VOL. 89. ISSUE 6-7. P. 779-788 64 88% 88
6 SILVERMAN, RH , (2007) VIRAL ENCOUNTERS WITH 2 ',5 '-OLIGOADENYLATE SYNTHETASE AND RNASE L DURING THE INTERFERON ANTIVIRAL RESPONSE.JOURNAL OF VIROLOGY. VOL. 81. ISSUE 23. P. 12720 -12729 72 67% 198
7 REBOUILLAT, D , HOVANESSIAN, AG , (1999) THE HUMAN 2 ',5 '-OLIGOADENYLATE SYNTHETASE FAMILY: INTERFERON-INDUCED PROTEINS WITH UNIQUE ENZYMATIC PROPERTIES.JOURNAL OF INTERFERON AND CYTOKINE RESEARCH. VOL. 19. ISSUE 4. P. 295 -308 71 86% 145
8 JUSTESEN, J , HARTMANN, R , KJELDGAARD, NO , (2000) GENE STRUCTURE AND FUNCTION OF THE 2 '-5 '-OLIGOADENYLATE SYNTHETASE FAMILY.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 57. ISSUE 11. P. 1593-1612 62 90% 119
9 SILVERMAN, RH , (2007) A SCIENTIFIC JOURNEY THROUGH THE 2-5A/RNASE L SYSTEM.CYTOKINE & GROWTH FACTOR REVIEWS. VOL. 18. ISSUE 5-6. P. 381-388 59 71% 49
10 EZELLE, HJ , MALATHI, K , HASSEL, BA , (2016) THE ROLES OF RNASE-L IN ANTIMICROBIAL IMMUNITY AND THE CYTOSKELETON-ASSOCIATED INNATE RESPONSE.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. VOL. 17. ISSUE 1. P. - 70 49% 0

Classes with closest relation at Level 1


Rank Class id link
1 8109 JOURNAL OF INTERFERON RESEARCH//HUMAN INTERFERON GAMMA//HIFN GAMMA
2 23898 POLY ICLC//RAUSCHER MURINE LEUKEMIA VIRUS//BANZI VIRUS
3 9561 PKR//NF90//VA RNA
4 4145 JOURNAL OF INTERFERON RESEARCH//TEXAS REPORTS ON BIOLOGY AND MEDICINE//UCLA SYMPOSIA ON MOLECULAR AND CELLULAR BIOLOGY
5 31822 BETA 1 3 LINKED D GLUCOPYRANOSYL RESIDUES WITH 1 6 LINKED BRANCHED SACCHARIDES//CAP 34//CHROMOSOME SHORTENING
6 22094 SECT STUDIES HOST IMMUNE PONSE//GENE IMMUNE MED//CANC BIOL 173
7 16143 SECT PHARMACOL MED ONCOL//INTERDIPARTIMENTALE EPIDEMIOL//NIKAIA GEN HOSP
8 25600 IFI16//HIN 200//P202
9 15225 MX PROTEIN//MX GENE//MXA PROTEIN
10 13382 INTERFERON RECEPTOR//IFNAR1//IFNAR2

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