Class information for:
Level 1: SINOATRIAL NODE//HCN CHANNELS//PACEMAKER CURRENT

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3300 2016 41.7 77%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
11 3       ATRIAL FIBRILLATION//CARDIAC & CARDIOVASCULAR SYSTEM//CATHETER ABLATION 130936
2637 2             IVABRADINE//SINOATRIAL NODE//HCN CHANNELS 3514
3300 1                   SINOATRIAL NODE//HCN CHANNELS//PACEMAKER CURRENT 2016

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SINOATRIAL NODE authKW 1690932 12% 47% 237
2 HCN CHANNELS authKW 1191635 6% 66% 120
3 PACEMAKER CURRENT authKW 574856 3% 72% 53
4 I H authKW 496712 3% 52% 63
5 HYPERPOLARIZATION ACTIVATED CURRENT authKW 451323 2% 65% 46
6 ZD7288 authKW 368418 2% 57% 43
7 HCN4 authKW 343576 2% 69% 33
8 MOL PHYSIOL NEUROBIOL address 275355 1% 91% 20
9 HYPERPOLARIZATION ACTIVATED CHANNELS authKW 243155 1% 94% 17
10 SINUS NODE authKW 243087 3% 31% 51

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Physiology 17606 32% 0% 652
2 Cardiac & Cardiovascular System 9941 28% 0% 567
3 Neurosciences 2905 24% 0% 478
4 Peripheral Vascular Diseases 2515 11% 0% 221
5 Cell Biology 389 9% 0% 183
6 Pharmacology & Pharmacy 303 10% 0% 196
7 Hematology 244 4% 0% 84
8 Biophysics 235 5% 0% 101
9 Mathematical & Computational Biology 138 2% 0% 37
10 Biochemistry & Molecular Biology 86 10% 0% 209

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL PHYSIOL NEUROBIOL 275355 1% 91% 20
2 CIMMBA 70335 1% 39% 12
3 DAVEE NEUROL CLIN NEUROSCI 57733 1% 25% 15
4 FISIOL MOL NEUROBIOL 48462 0% 80% 4
5 PHARM PHARMAKOL NAT WISSEN 42064 0% 56% 5
6 BIOENERGET BIOELECT SYST 30289 0% 100% 2
7 COGNIT SCISTATE ETHN AFFAIRS COMMISS 30289 0% 100% 2
8 RG EXPT NEUROPEDIAT 30289 0% 100% 2
9 SECT PHARMACOL NEUROBIOL 30289 0% 100% 2
10 CORE TECHNOL IL 24996 1% 8% 20

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF PHYSIOLOGY-LONDON 18001 7% 1% 148
2 PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 15134 5% 1% 91
3 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 11680 4% 1% 71
4 CIRCULATION RESEARCH 7475 4% 1% 71
5 JOURNAL OF GENERAL PHYSIOLOGY 6208 2% 1% 37
6 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 6056 4% 1% 71
7 CARDIOVASCULAR RESEARCH 4581 2% 1% 49
8 JAPANESE JOURNAL OF PHYSIOLOGY 4523 1% 1% 25
9 JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY 4092 2% 1% 34
10 AMERICAN JOURNAL OF PHYSIOLOGY 1905 3% 0% 57

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SINOATRIAL NODE 1690932 12% 47% 237 Search SINOATRIAL+NODE Search SINOATRIAL+NODE
2 HCN CHANNELS 1191635 6% 66% 120 Search HCN+CHANNELS Search HCN+CHANNELS
3 PACEMAKER CURRENT 574856 3% 72% 53 Search PACEMAKER+CURRENT Search PACEMAKER+CURRENT
4 I H 496712 3% 52% 63 Search I+H Search I+H
5 HYPERPOLARIZATION ACTIVATED CURRENT 451323 2% 65% 46 Search HYPERPOLARIZATION+ACTIVATED+CURRENT Search HYPERPOLARIZATION+ACTIVATED+CURRENT
6 ZD7288 368418 2% 57% 43 Search ZD7288 Search ZD7288
7 HCN4 343576 2% 69% 33 Search HCN4 Search HCN4
8 HYPERPOLARIZATION ACTIVATED CHANNELS 243155 1% 94% 17 Search HYPERPOLARIZATION+ACTIVATED+CHANNELS Search HYPERPOLARIZATION+ACTIVATED+CHANNELS
9 SINUS NODE 243087 3% 31% 51 Search SINUS+NODE Search SINUS+NODE
10 I F 215388 1% 89% 16 Search I+F Search I+F

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BIEL, M , WAHL-SCHOTT, C , MICHALAKIS, S , ZONG, XG , (2009) HYPERPOLARIZATION-ACTIVATED CATION CHANNELS: FROM GENES TO FUNCTION.PHYSIOLOGICAL REVIEWS. VOL. 89. ISSUE 3. P. 847 -885 252 59% 324
2 MANGONI, ME , NARGEOT, J , (2008) GENESIS AND REGULATION OF THE HEART AUTOMATICITY.PHYSIOLOGICAL REVIEWS. VOL. 88. ISSUE 3. P. 919-982 239 49% 201
3 ROMANELLI, MN , SARTIANI, L , MASI, A , MANNAIONI, G , MANETTI, D , MUGELLI, A , CERBAI, E , (2016) HCN CHANNELS MODULATORS: THE NEED FOR SELECTIVITY.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 16. ISSUE 16. P. 1764 -1791 177 66% 0
4 HE, C , CHEN, F , LI, B , HU, Z , (2014) NEUROPHYSIOLOGY OF HCN CHANNELS: FROM CELLULAR FUNCTIONS TO MULTIPLE REGULATIONS.PROGRESS IN NEUROBIOLOGY. VOL. 112. ISSUE . P. 1-23 132 55% 62
5 POSTEA, O , BIEL, M , (2011) EXPLORING HCN CHANNELS AS NOVEL DRUG TARGETS.NATURE REVIEWS DRUG DISCOVERY. VOL. 10. ISSUE 12. P. 903 -914 112 82% 70
6 WICKENDEN, AD , MAHER, MP , CHAPLAN, SR , (2009) HCN PACEMAKER CHANNELS AND PAIN: A DRUG DISCOVERY PERSPECTIVE.CURRENT PHARMACEUTICAL DESIGN. VOL. 15. ISSUE 18. P. 2149-2168 138 75% 24
7 VERKERK, AO , VAN GINNEKEN, ACG , WILDERS, R , (2009) PACEMAKER ACTIVITY OF THE HUMAN SINOATRIAL NODE: ROLE OF THE HYPERPOLARIZATION-ACTIVATED CURRENT, I-F.INTERNATIONAL JOURNAL OF CARDIOLOGY. VOL. 132. ISSUE 3. P. 318 -336 124 82% 20
8 DIFRANCESCO, D , (2010) THE ROLE OF THE FUNNY CURRENT IN PACEMAKER ACTIVITY.CIRCULATION RESEARCH. VOL. 106. ISSUE 3. P. 434-446 85 81% 169
9 ROBINSON, RB , (2003) HYPERPOLARIZATION-ACTIVATED CATION CURRENTS: FROM MOLECULES TO PHYSIOLOGICAL FUNCTION.ANNUAL REVIEW OF PHYSIOLOGY. VOL. 65. ISSUE . P. 453-480 94 69% 635
10 WAHL-SCHOTT, C , BIEL, M , (2009) HCN CHANNELS: STRUCTURE, CELLULAR REGULATION AND PHYSIOLOGICAL FUNCTION.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 66. ISSUE 3. P. 470 -494 127 54% 155

Classes with closest relation at Level 1


Rank Class id link
1 26073 ZATEBRADINE//ALINIDINE//YM758
2 20758 SINUS NODE ELECTROGRAM//SINOATRIAL CONDUCTION//SINOATRIAL CONDUCTION TIME
3 10195 IVABRADINE//RESTING HEART RATE//HOWARD GILMAN HEART VALVE DIS
4 7174 R 56865//DELAYED AFTERDEPOLARIZATION//DIASTOLIC DEPOLARIZATION
5 23085 PARASYSTOLE//SUPERNORMAL CONDUCTION//ESCAPE CAPTURE BIGEMINY
6 2752 BIDOMAIN MODEL//BIDOMAIN//OPTICAL MAPPING
7 7026 TRANSIENT OUTWARD CURRENT//KV43//KCHIP
8 5440 GIRK//ANDERSEN TAWIL SYNDROME//INWARD RECTIFIER
9 6586 SYNAPTIC INTEGRATION//DENDRITIC INTEGRATION//DENDRITE
10 7460 CARDIOMYOCYTES//CARDIAC DIFFERENTIATION//STEM CELL REGENERAT MED CONSORTIUM

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