Class information for:
Level 1: CFU GM ASSAY//PYRAZINE DIAZOHYDROXIDE//SR 4987 CELLS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
30330 170 29.0 62%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
51 3       HEMATOLOGY//BONE MARROW TRANSPLANTATION//BLOOD 91443
209 2             EXPERIMENTAL HEMATOLOGY//THROMBOPOIETIN//HEMATOLOGY 20851
30330 1                   CFU GM ASSAY//PYRAZINE DIAZOHYDROXIDE//SR 4987 CELLS 170

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CFU GM ASSAY authKW 733445 4% 58% 7
2 PYRAZINE DIAZOHYDROXIDE authKW 538862 2% 100% 3
3 SR 4987 CELLS authKW 538862 2% 100% 3
4 HEMATOTOXICOLOGY authKW 410558 2% 57% 4
5 ACUTE NEUTROPENIA authKW 404145 2% 75% 3
6 BFU E CFU E authKW 359241 1% 100% 2
7 COLONY FORMING UNIT GRANULOCYTE MACROPHAGES authKW 359241 1% 100% 2
8 ESMISAB ISAMOR address 359241 1% 100% 2
9 HEMATOTOXICITY INVITRO authKW 359241 1% 100% 2
10 HEMATOTOXICITY authKW 340585 9% 12% 16

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Toxicology 2049 33% 0% 56
2 Pharmacology & Pharmacy 199 22% 0% 37
3 Oncology 189 19% 0% 32
4 Medical Informatics 129 4% 0% 6
5 Cell & Tissue Engineering 102 2% 0% 4
6 Medicine, Research & Experimental 99 10% 0% 17
7 Cell Biology 81 13% 0% 22
8 Hematology 73 7% 0% 12
9 Pathology 58 6% 0% 10
10 Engineering, Biomedical 34 4% 0% 7

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ESMISAB ISAMOR 359241 1% 100% 2
2 MICROBIOL SECUR ALIMENTAIRE 258644 4% 24% 6
3 ESMISAB UBO 179621 1% 100% 1
4 EUROPEAN VALIDAT ALTERNAT MEHTODS 179621 1% 100% 1
5 GAIL WALTER 179621 1% 100% 1
6 HCV ANIM PATHOL 179621 1% 100% 1
7 PATHOL P CORE S 179621 1% 100% 1
8 PRECLIN BIOMETR 179621 1% 100% 1
9 RECH ELECT SIGNAL OPTRON TELECOMMUN 179621 1% 100% 1
10 SA POLIGONO IND LA MINA 179621 1% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TOXICOLOGY IN VITRO 15003 11% 0% 19
2 CELL BIOLOGY AND TOXICOLOGY 7515 4% 1% 7
3 IN VITRO & MOLECULAR TOXICOLOGY-A JOURNAL OF BASIC AND APPLIED RESEARCH 7328 1% 2% 2
4 INVESTIGATIONAL NEW DRUGS 4497 5% 0% 8
5 ATLA-ALTERNATIVES TO LABORATORY ANIMALS 3275 3% 0% 5
6 METHODS IN MOLECULAR AND CELLULAR BIOLOGY 2895 1% 2% 1
7 THERAPEUTIC INNOVATION & REGULATORY SCIENCE 1975 1% 1% 2
8 PATHOBIOLOGY 1477 2% 0% 3
9 TOXICOLOGIC PATHOLOGY 1125 2% 0% 4
10 STEM CELLS TRANSLATIONAL MEDICINE 1051 1% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CFU GM ASSAY 733445 4% 58% 7 Search CFU+GM+ASSAY Search CFU+GM+ASSAY
2 PYRAZINE DIAZOHYDROXIDE 538862 2% 100% 3 Search PYRAZINE+DIAZOHYDROXIDE Search PYRAZINE+DIAZOHYDROXIDE
3 SR 4987 CELLS 538862 2% 100% 3 Search SR+4987+CELLS Search SR+4987+CELLS
4 HEMATOTOXICOLOGY 410558 2% 57% 4 Search HEMATOTOXICOLOGY Search HEMATOTOXICOLOGY
5 ACUTE NEUTROPENIA 404145 2% 75% 3 Search ACUTE+NEUTROPENIA Search ACUTE+NEUTROPENIA
6 BFU E CFU E 359241 1% 100% 2 Search BFU+E+CFU+E Search BFU+E+CFU+E
7 COLONY FORMING UNIT GRANULOCYTE MACROPHAGES 359241 1% 100% 2 Search COLONY+FORMING+UNIT+GRANULOCYTE+MACROPHAGES Search COLONY+FORMING+UNIT+GRANULOCYTE+MACROPHAGES
8 HEMATOTOXICITY INVITRO 359241 1% 100% 2 Search HEMATOTOXICITY+INVITRO Search HEMATOTOXICITY+INVITRO
9 HEMATOTOXICITY 340585 9% 12% 16 Search HEMATOTOXICITY Search HEMATOTOXICITY
10 MYELOTOXICITY 277185 8% 11% 14 Search MYELOTOXICITY Search MYELOTOXICITY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 YADAV, NK , SHUKLA, P , OMER, A , SINGH, P , SINGH, RK , (2016) ALTERNATIVE METHODS IN TOXICOLOGY: CFU ASSAYS APPLICATION, LIMITATION AND FUTURE PROSPECTIVE.DRUG AND CHEMICAL TOXICOLOGY. VOL. 39. ISSUE 1. P. 1 -12 36 39% 0
2 PARENT-MASSIN, D , HYMERY, N , SIBIRIL, Y , (2010) STEM CELLS IN MYELOTOXICITY.TOXICOLOGY. VOL. 267. ISSUE 1-3. P. 112 -117 22 43% 7
3 HAGLUND, C , ALESKOG, A , HAKANSSON, LD , HOGLUND, M , JACOBSSON, S , LARSSON, R , LINDHAGEN, E , (2010) THE FMCA-GM ASSAYS, HIGH THROUGHPUT NON-CLONOGENIC ALTERNATIVES TO CFU-GM IN PRECLINICAL HEMATOTOXICITY TESTING.TOXICOLOGY LETTERS. VOL. 194. ISSUE 3. P. 102-107 15 60% 7
4 GUO, L , HAMRE, J , DAVIS, M , PARCHMENT, RE , (2016) HUMAN CD34(+) PROGENITOR HEMATOPOIESIS IN LIQUID CULTURE FOR IN VITRO ASSESSMENT OF DRUG-INDUCED MYELOTOXICITY.TOXICOLOGY IN VITRO. VOL. 31. ISSUE . P. 103 -113 14 56% 0
5 PESSINA, A , BONOMI, A , BAGLIO, C , CAVICCHINI, L , GRIBALDO, L , (2009) REFINEMENT AND OPTIMISATION OF THE RAT CFU-GM ASSAY TO INCORPORATE THE USE OF CRYOPRESERVED BONE-MARROW CELLS FOR IN VITRO TOXICOLOGY APPLICATIONS.ATLA-ALTERNATIVES TO LABORATORY ANIMALS. VOL. 37. ISSUE 4. P. 417-425 9 75% 1
6 PESSINA, A , MALERBA, F , GRIBALDO, L , (2005) HEMATOTOXICITY TESTING BY CELL CLONOGENIC ASSAY IN DRUG DEVELOPMENT AND PRECLINICAL TRIALS.CURRENT PHARMACEUTICAL DESIGN. VOL. 11. ISSUE 8. P. 1055 -1065 19 37% 36
7 MANDARAPU, R , PRAKHYA, BM , (2015) IN VITRO MYELOTOXIC EFFECTS OF CYPERMETHRIN AND MANCOZEB ON HUMAN HEMATOPOIETIC PROGENITOR CELLS.JOURNAL OF IMMUNOTOXICOLOGY. VOL. 12. ISSUE 1. P. 48 -55 12 43% 3
8 CROSTA, GF , FUMAROLA, L , MALERBA, F , GRIBALDO, L , (2007) SCORING CFU-GM COLONIES IN VITRO BY DATA FUSION: A FIRST ACCOUNT.EXPERIMENTAL HEMATOLOGY. VOL. 35. ISSUE 1. P. 1-12 10 59% 2
9 WHITEHEAD, RP , UNGER, JM , FLAHERTY, LE , KRAUT, EH , MILLS, GM , KLEIN, CE , CHAPMAN, RA , DOOLITTLE, GC , HAMMOND, N , SONDAK, VK , (2002) A PHASE II TRIAL OF PYRAZINE DIAZOHYDROXIDE IN PATIENTS WITH DISSEMINATED MALIGNANT MELANOMA AND NO PRIOR CHEMOTHERAPY - SOUTHWEST ONCOLOGY GROUP STUDY.INVESTIGATIONAL NEW DRUGS. VOL. 20. ISSUE 1. P. 105-111 6 100% 4
10 CERRATO, L , VALERI, A , BUEREN, JA , ALBELLA, B , (2009) IN VITRO SENSITIVITY OF GRANULO-MONOCYTIC PROGENITORS AS A NEW TOXICOLOGICAL CELL SYSTEM AND ENDPOINT IN THE ACUTETOX PROJECT.TOXICOLOGY AND APPLIED PHARMACOLOGY. VOL. 238. ISSUE 2. P. 111-119 11 42% 5

Classes with closest relation at Level 1


Rank Class id link
1 36901 BRILLANTAISIA NITENS//HAEMATINIC ACTIVITY//METHYLENE CHLORIDE METHANOL EXTRACT
2 33571 MOL FOOD MICROBIOL//AUTOMATED COLONY COUNTING//BACTERIAL COLONY COUNTING
3 34665 DINALINE//ACETYLDINALINE//SEMI ALLOGENEIC
4 30871 PROPANIL//PCT ABS//POLYCHLORINATED AZOBENZENES
5 35959 CARBOXYAMIDOTRIAZOLE//PROOFREADING STIMULATION//EQUIMOLAR COMBINATIONS OF NUCLEOTIDES PRECURSORS
6 16177 AGRANULOCYTOSIS//DRUG INDUCED AGRANULOCYTOSIS//EVALUATION SCORE
7 10061 CFU S//EXPERIMENTAL HEMATOLOGY//FRANKEL BONE MARROW TRANSPLANTAT
8 34583 CHENOPODIUM AMBROSIOIDES//ASCARIDOLE//MASTRUZ
9 27104 ANGELICA SINENSIS POLYSACCHARIDE IRON COMPLEX//16 RUE H HUCHARD//AEROGENIC HYPOXIA
10 5405 ZIDOVUDINE//DIDANOSINE//ZALCITABINE

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