Class information for:
Level 1: ZNF217//CTBP//CTBP1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
29445 186 44.0 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
27 3       DEVELOPMENTAL BIOLOGY//DEVELOPMENT//AGR2 109777
2641 2             EPITHELIAL MESENCHYMAL TRANSITION//EMT//SNAIL 3501
29445 1                   ZNF217//CTBP//CTBP1 186

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ZNF217 authKW 1237570 8% 54% 14
2 CTBP authKW 1165938 13% 28% 25
3 CTBP1 authKW 945916 6% 52% 11
4 C TERMINAL BINDING PROTEIN authKW 864038 5% 53% 10
5 CTBP2 authKW 552981 4% 42% 8
6 ANGUSTIFOLIA authKW 393999 3% 40% 6
7 C TERMINAL BINDING PROTEIN 2 CTBP2 authKW 328338 1% 100% 2
8 MTOB authKW 218891 1% 67% 2
9 2 HYBRID ANALYSIS authKW 164169 1% 100% 1
10 2 KETO 4 METHYLTHIOBUTYRATE authKW 164169 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 1345 44% 0% 81
2 Biochemistry & Molecular Biology 839 55% 0% 103
3 Oncology 613 31% 0% 57
4 Genetics & Heredity 97 11% 0% 20
5 Biophysics 82 9% 0% 16
6 Developmental Biology 14 2% 0% 4
7 Dermatology 4 2% 0% 3
8 Microscopy 3 1% 0% 1
9 Biotechnology & Applied Microbiology 3 3% 0% 6
10 Biochemical Research Methods 2 2% 0% 4

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOMED INFORMAT COUNTWAY 164169 1% 100% 1
2 BIOMED SCI BIOCHEM MOL BIOLCAN 164169 1% 100% 1
3 BRUSH CANC 164169 1% 100% 1
4 CANS SCI 164169 1% 100% 1
5 ENDOCRINOL MOL TRANSDUCC SENALESIBYME CONI 164169 1% 100% 1
6 INFLAMAC CANC QUIM BIOL 164169 1% 100% 1
7 INFLAMAC CANCIQUIBICENCONICET 164169 1% 100% 1
8 MED TOXICOL EVALUAT SECT 164169 1% 100% 1
9 METAB CHECKPOINT MED 164169 1% 100% 1
10 PEDIAT STRUCT CHEM BIOL 164169 1% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER DISCOVERY 1424 1% 0% 2
2 MOLECULAR AND CELLULAR BIOLOGY 881 6% 0% 11
3 JOURNAL OF MOLECULAR HISTOLOGY 814 1% 0% 2
4 ONCOGENE 572 4% 0% 8
5 DEVELOPMENT GENES AND EVOLUTION 518 1% 0% 2
6 NEOPLASIA 386 1% 0% 2
7 ONCOTARGET 327 3% 0% 5
8 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 295 2% 0% 3
9 NEUROGENETICS 270 1% 0% 1
10 MOLECULAR CELL 266 2% 0% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ZNF217 1237570 8% 54% 14 Search ZNF217 Search ZNF217
2 CTBP 1165938 13% 28% 25 Search CTBP Search CTBP
3 CTBP1 945916 6% 52% 11 Search CTBP1 Search CTBP1
4 C TERMINAL BINDING PROTEIN 864038 5% 53% 10 Search C+TERMINAL+BINDING+PROTEIN Search C+TERMINAL+BINDING+PROTEIN
5 CTBP2 552981 4% 42% 8 Search CTBP2 Search CTBP2
6 ANGUSTIFOLIA 393999 3% 40% 6 Search ANGUSTIFOLIA Search ANGUSTIFOLIA
7 C TERMINAL BINDING PROTEIN 2 CTBP2 328338 1% 100% 2 Search C+TERMINAL+BINDING+PROTEIN+2+CTBP2 Search C+TERMINAL+BINDING+PROTEIN+2+CTBP2
8 MTOB 218891 1% 67% 2 Search MTOB Search MTOB
9 2 HYBRID ANALYSIS 164169 1% 100% 1 Search 2+HYBRID+ANALYSIS Search 2+HYBRID+ANALYSIS
10 2 KETO 4 METHYLTHIOBUTYRATE 164169 1% 100% 1 Search 2+KETO+4+METHYLTHIOBUTYRATE Search 2+KETO+4+METHYLTHIOBUTYRATE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KORWAR, S , MORRIS, BL , PARIKH, HI , COOVER, RA , DOUGHTY, TW , LOVE, IM , HILBERT, BJ , ROYER, WE , KELLOGG, GE , GROSSMAN, SR , ET AL (2016) DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF SUBSTRATE-COMPETITIVE INHIBITORS OF C-TERMINAL BINDING PROTEIN (CTBP).BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 24. ISSUE 12. P. 2707 -2715 24 83% 0
2 MADISON, DL , WIRZ, JA , SIESS, D , LUNDBLAD, JR , (2013) NICOTINAMIDE ADENINE DINUCLEOTIDE-INDUCED MULTIMERIZATION OF THE CO-REPRESSOR CTBP1 RELIES ON A SWITCHING TRYPTOPHAN.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 288. ISSUE 39. P. 27836-27848 26 70% 1
3 HILBERT, BJ , MORRIS, BL , ELLIS, KC , PAULSEN, JL , SCHIFFER, CA , GROSSMAN, SR , ROYER, WE , (2015) STRUCTURE-GUIDED DESIGN OF A HIGH AFFINITY INHIBITOR TO HUMAN CTBP.ACS CHEMICAL BIOLOGY. VOL. 10. ISSUE 4. P. 1118 -1127 23 68% 0
4 HILBERT, BJ , GROSSMAN, SR , SCHIFFER, CA , ROYER, WE , (2014) CRYSTAL STRUCTURES OF HUMAN CTBP IN COMPLEX WITH SUBSTRATE MTOB REVEAL ACTIVE SITE FEATURES USEFUL FOR INHIBITOR DESIGN.FEBS LETTERS. VOL. 588. ISSUE 9. P. 1743 -1748 24 65% 2
5 BIRTS, CN , HARDING, R , SOOSAIPILLAI, G , HAIDER, T , AZIM-ARAGHI, A , DARLEY, M , CUTRESS, RI , BATEMANT, AC , BLAYDES, JP , (2011) EXPRESSION OF CTBP FAMILY PROTEIN ISOFORMS IN BREAST CANCER AND THEIR ROLE IN CHEMORESISTANCE.BIOLOGY OF THE CELL. VOL. 103. ISSUE 1. P. 1 -19 26 58% 6
6 ZHAO, LJ , SUBRAMANIAN, T , ZHOU, Y , CHINNADURAI, G , (2006) ACETYLATION BY P300 REGULATES NUCLEAR LOCALIZATION AND FUNCTION OF THE TRANSCRIPTIONAL COREPRESSOR CTBP2.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 281. ISSUE 7. P. 4183-4189 28 57% 48
7 ZHANG, YW , ARNOSTI, DN , (2011) CONSERVED CATALYTIC AND C-TERMINAL REGULATORY DOMAINS OF THE C-TERMINAL BINDING PROTEIN COREPRESSOR FINE-TUNE THE TRANSCRIPTIONAL RESPONSE IN DEVELOPMENT.MOLECULAR AND CELLULAR BIOLOGY. VOL. 31. ISSUE 2. P. 375-384 25 57% 5
8 BLEVINS, MA , KOUZNETSOVA, J , KRUEGER, AB , KING, R , GRINER, LM , HU, X , SOUTHALL, N , MARUGAN, JJ , ZHANG, QH , FERRER, M , ET AL (2015) SMALL MOLECULE, NSC95397, INHIBITS THE CTBP1-PROTEIN PARTNER INTERACTION AND CTBP1-MEDIATED TRANSCRIPTIONAL REPRESSION.JOURNAL OF BIOMOLECULAR SCREENING. VOL. 20. ISSUE 5. P. 663 -672 18 69% 3
9 COHEN, PA , DONINI, CF , NGUYEN, NT , LINCET, H , VENDRELL, JA , (2015) THE DARK SIDE OF ZNF217, A KEY REGULATOR OF TUMORIGENESIS WITH POWERFUL BIOMARKER VALUE.ONCOTARGET. VOL. 6. ISSUE 39. P. 41566 -41581 32 35% 4
10 STRAZA, MW , PALIWAL, S , KOVI, RC , RAJESHKUMAR, B , TRENH, P , PARKER, D , WHALEN, GF , LYLE, S , SCHIFFER, CA , GROSSMAN, SR , (2010) THERAPEUTIC TARGETING OF C-TERMINAL BINDING PROTEIN IN HUMAN CANCER.CELL CYCLE. VOL. 9. ISSUE 18. P. 3740 -3750 24 53% 17

Classes with closest relation at Level 1


Rank Class id link
1 25417 MOWAT WILSON SYNDROME//ATBF1//ZFHX1B
2 35060 MIR 494//MIR 503//MICRORNA 503
3 23684 HIPK2//SIAH2//SIAH1
4 3242 E1A//ADENOVIRUS E1A//E4ORF6
5 34723 CSE1L//PHOSPHO CSE1L//CELLULAR APOPTOSIS SUSCEPTIBILITY
6 5286 BICOID//GAP GENES//HUNCHBACK
7 35662 A33 ANTIGEN//ADHESION REGULATING MOLECULE 1//ADRM1
8 8082 HISTONE DEMETHYLASE//LSD1//HISTONE DEMETHYLATION
9 36990 TIP30//HTATIP2 TIP30//EASTERN HOSP HEPATOBILIARY SURG
10 16735 EVI1//EVI 1//RIZ1

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