Class information for:
Level 1: APTAMER//SELEX//APTASENSOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
293 3718 44.2 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
183 3       APTAMER//G QUADRUPLEX//RIBOZYME 56307
1286 2             APTAMER//SELEX//APTASENSOR 8682
293 1                   APTAMER//SELEX//APTASENSOR 3718

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 APTAMER authKW 5705442 37% 50% 1382
2 SELEX authKW 1893496 10% 62% 372
3 APTASENSOR authKW 875258 5% 54% 197
4 DNA APTAMER authKW 574213 3% 64% 110
5 ELECTROCHEMICAL APTASENSOR authKW 438784 2% 74% 72
6 CELL SELEX authKW 323016 1% 91% 43
7 THROMBIN authKW 161795 8% 7% 280
8 RNA APTAMER authKW 160104 1% 37% 53
9 IN VITRO SELECTION authKW 123794 2% 18% 86
10 BIO NANO INTER E address 108856 1% 24% 55

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Chemistry, Analytical 32900 40% 0% 1503
2 Electrochemistry 11196 15% 0% 561
3 Nanoscience & Nanotechnology 5027 13% 0% 489
4 Biotechnology & Applied Microbiology 4029 15% 0% 560
5 Biophysics 3996 13% 0% 473
6 Biochemical Research Methods 2602 10% 0% 358
7 Biochemistry & Molecular Biology 1744 22% 0% 803
8 Chemistry, Multidisciplinary 1339 15% 0% 554
9 Chemistry, Medicinal 516 4% 0% 158
10 Materials Science, Biomaterials 326 2% 0% 67

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIO NANO INTER E 108856 1% 24% 55
2 SHANDS CANC 77758 2% 12% 77
3 UF GENET 68012 1% 19% 43
4 TARGETED DRUG DELIVERY 55102 1% 22% 30
5 STATE CHEMO BIOSENSING CHEMOMETR 50844 4% 5% 132
6 PROGRAM UNIT CHEM BIOL MED CHEM 34760 0% 35% 12
7 BIONANOTECHNOL MOL ENGN HUNAN PROV 34377 1% 15% 28
8 RNA SCI TECHNOL 34211 0% 83% 5
9 DUKE TRANSLAT 31519 0% 30% 13
10 LUMINESCENCE REAL TIME ANAL 29263 1% 8% 47

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOSENSORS & BIOELECTRONICS 101263 9% 4% 344
2 NUCLEIC ACID THERAPEUTICS 54272 1% 16% 41
3 ANALYTICAL CHEMISTRY 15076 7% 1% 259
4 ANALYST 10833 4% 1% 140
5 OLIGONUCLEOTIDES 8790 0% 6% 17
6 MOLECULAR THERAPY-NUCLEIC ACIDS 8775 0% 6% 18
7 MICROCHIMICA ACTA 4283 1% 1% 40
8 ANALYTICAL AND BIOANALYTICAL CHEMISTRY 4227 2% 1% 76
9 ANALYTICAL METHODS 4209 2% 1% 56
10 TALANTA 3928 2% 1% 91

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 APTAMER 5705442 37% 50% 1382 Search APTAMER Search APTAMER
2 SELEX 1893496 10% 62% 372 Search SELEX Search SELEX
3 APTASENSOR 875258 5% 54% 197 Search APTASENSOR Search APTASENSOR
4 DNA APTAMER 574213 3% 64% 110 Search DNA+APTAMER Search DNA+APTAMER
5 ELECTROCHEMICAL APTASENSOR 438784 2% 74% 72 Search ELECTROCHEMICAL+APTASENSOR Search ELECTROCHEMICAL+APTASENSOR
6 CELL SELEX 323016 1% 91% 43 Search CELL+SELEX Search CELL+SELEX
7 THROMBIN 161795 8% 7% 280 Search THROMBIN Search THROMBIN
8 RNA APTAMER 160104 1% 37% 53 Search RNA+APTAMER Search RNA+APTAMER
9 IN VITRO SELECTION 123794 2% 18% 86 Search IN+VITRO+SELECTION Search IN+VITRO+SELECTION
10 STRUCTURE SWITCHING 97229 0% 79% 15 Search STRUCTURE+SWITCHING Search STRUCTURE+SWITCHING

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LIU, JW , CAO, ZH , LU, Y , (2009) FUNCTIONAL NUCLEIC ACID SENSORS.CHEMICAL REVIEWS. VOL. 109. ISSUE 5. P. 1948-1998 257 43% 861
2 STOLTENBURG, R , REINEMANN, C , STREHLITZ, B , (2007) SELEX-A (R)EVOLUTIONARY METHOD TO GENERATE HIGH-AFFINITY NUCLEIC ACID LIGANDS.BIOMOLECULAR ENGINEERING. VOL. 24. ISSUE 4. P. 381 -403 180 68% 455
3 MA, HT , LIU, JP , ALI, MM , MAHMOOD, MAI , LABANIEH, L , LU, MR , IQBAL, SM , ZHANG, Q , ZHAO, WA , WAN, Y , (2015) NUCLEIC ACID APTAMERS IN CANCER RESEARCH, DIAGNOSIS AND THERAPY.CHEMICAL SOCIETY REVIEWS. VOL. 44. ISSUE 5. P. 1240 -1256 168 64% 27
4 ILIUK, AB , HU, LH , TAO, WA , (2011) APTAMER IN BIOANALYTICAL APPLICATIONS.ANALYTICAL CHEMISTRY. VOL. 83. ISSUE 12. P. 4440-4452 118 76% 295
5 DARMOSTUK, M , RIMPELOVA, S , GBELCOVA, H , RUML, T , (2015) CURRENT APPROACHES IN SELEX: AN UPDATE TO APTAMER SELECTION TECHNOLOGY.BIOTECHNOLOGY ADVANCES. VOL. 33. ISSUE 6. P. 1141 -1161 133 64% 33
6 SUN, HG , ZHU, X , LU, PY , ROSATO, RR , TAN, W , ZU, YL , (2014) OLIGONUCLEOTIDE APTAMERS: NEW TOOLS FOR TARGETED CANCER THERAPY.MOLECULAR THERAPY-NUCLEIC ACIDS. VOL. 3. ISSUE . P. - 107 78% 70
7 KEEFE, AD , PAI, S , ELLINGTON, A , (2010) APTAMERS AS THERAPEUTICS.NATURE REVIEWS DRUG DISCOVERY. VOL. 9. ISSUE 7. P. 537-550 98 64% 585
8 OZER, A , PAGANO, JM , LIS, JT , (2014) NEW TECHNOLOGIES PROVIDE QUANTUM CHANGES IN THE SCALE, SPEED, AND SUCCESS OF SELEX METHODS AND APTAMER CHARACTERIZATION.MOLECULAR THERAPY-NUCLEIC ACIDS. VOL. 3. ISSUE . P. - 132 75% 31
9 XI, ZJ , HUANG, RR , DENG, Y , HE, NY , (2014) PROGRESS IN SELECTION AND BIOMEDICAL APPLICATIONS OF APTAMERS.JOURNAL OF BIOMEDICAL NANOTECHNOLOGY. VOL. 10. ISSUE 10. P. 3043 -3062 166 61% 26
10 MASCINI, M , PALCHETTI, I , TOMBELLI, S , (2012) NUCLEIC ACID AND PEPTIDE APTAMERS: FUNDAMENTALS AND BIOANALYTICAL ASPECTS.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. VOL. 51. ISSUE 6. P. 1316 -1332 135 63% 112

Classes with closest relation at Level 1


Rank Class id link
1 11256 DEOXYRIBOZYME//DNAZYME//CATALYTIC DNA
2 4182 HYBRIDIZATION CHAIN REACTION//ROLLING CIRCLE AMPLIFICATION//DNAZYME
3 30665 PERSONAL GLUCOSE METER//SYNTH LIQUID CRYSTALS//PROTEIN ANTIBODY
4 28738 ELECTROCHEMICAL CYTOSENSOR//CYTOSENSOR//CHEMLIFE ENVIRONM SCI
5 28865 UNITE RECH PHYS SEMICOND C TEURS//OPEN GENOME INFECT DIS//BIOMED NANO DIAGNOST GRP
6 12082 RIBOSWITCH//CANC UK NUCLE ACID STRUCT GRP//RNA SWITCH
7 6080 MERCURY ION//COLORIMETRIC DETECTION//MERCURYII ION
8 24154 IMMUNO PCR//PROXIMITY LIGATION ASSAY//LEHRSTUHL BIOL CHEM MIKROSTRUKTURTECH
9 12480 MOLECULAR BEACON//IN VIVO HYBRIDIZATION//RNA IMAGING
10 29940 CHARGE CHANGING SUBSTRATE//IN GEL PROTEASE ACTIVITY ASSAY//SUBSTRATE SPECIFIC ZYMOGRAPHY

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