Class information for:
Level 1: OTILONIUM BROMIDE//OTILONIUM//PINAVERIUM

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
28776 200 24.2 39%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
6 4 GASTROENTEROLOGY & HEPATOLOGY//ONCOLOGY//SURGERY 1371034
337 3       IRRITABLE BOWEL SYNDROME//CONSTIPATION//ENTERIC NERVOUS SYSTEM 37464
111 2             IRRITABLE BOWEL SYNDROME//NEUROGASTROENTEROLOGY AND MOTILITY//FUNCTIONAL DYSPEPSIA 25141
28776 1                   OTILONIUM BROMIDE//OTILONIUM//PINAVERIUM 200

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 OTILONIUM BROMIDE authKW 955632 7% 48% 13
2 OTILONIUM authKW 488565 2% 80% 4
3 PINAVERIUM authKW 348973 2% 57% 4
4 PINAVERIUM BROMIDE authKW 274816 2% 60% 3
5 BENZOCAINE HYDROCHLORIDE authKW 152677 1% 100% 1
6 GASTROINTESTINAL AFFERENTS authKW 152677 1% 100% 1
7 GUT SPASMOLYTIC authKW 152677 1% 100% 1
8 JEJUNUM COLON authKW 152677 1% 100% 1
9 LIZARD LIOLAEMUS TENUIS TENUIS authKW 152677 1% 100% 1
10 MUSCLE BATH authKW 152677 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 1231 46% 0% 92
2 Gastroenterology & Hepatology 133 9% 0% 17
3 Spectroscopy 127 8% 0% 15
4 Chemistry, Multidisciplinary 117 18% 0% 36
5 Physiology 43 6% 0% 12
6 Medicine, Research & Experimental 41 7% 0% 13
7 Chemistry, Medicinal 32 5% 0% 9
8 Crystallography 22 4% 0% 7
9 Zoology 12 4% 0% 7
10 Chemistry, Analytical 6 4% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 STATE BIOMOL ELECT 152677 1% 100% 1
2 UNITE FONCTIONNELLE EXPLORAT FIBRE MUSCULAIRE LIS 152677 1% 100% 1
3 UNIV MELBOURNE CLIN PHARMACOL THER EUT UNIT 152677 1% 100% 1
4 PRECLIN DEV 17527 4% 1% 8
5 ENTER NEUROSCI PROGRAM 14362 2% 2% 4
6 BIOCHIM MEMBRANES 12721 1% 8% 1
7 ORG STATE DRUG CLIN TRIAL 11743 1% 8% 1
8 NEUROMUSCULAR PHYSIOL 10904 1% 7% 1
9 HISTOL EMBRYOL UNIT 10710 1% 4% 2
10 HPLC 5870 1% 4% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE 13248 7% 1% 14
2 ACTA BIOLOGICA CRACOVIENSIA SERIES ZOOLOGIA 7727 1% 3% 2
3 JOURNAL OF PHARMACOLOGICAL METHODS 7089 3% 1% 6
4 SPECTROSCOPY LETTERS 3007 4% 0% 8
5 NEUROGASTROENTEROLOGY AND MOTILITY 2892 4% 0% 7
6 JOURNAL DE MEDECINE DE STRASBOURG 2879 1% 2% 1
7 ACTA THERAPEUTICA 2459 1% 1% 2
8 REVUE ROUMAINE DE CHIMIE 2011 4% 0% 8
9 REVUE ROUMAINE DE BIOCHIMIE 2005 1% 1% 2
10 COSMETICS & TOILETRIES 1838 1% 1% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 OTILONIUM BROMIDE 955632 7% 48% 13 Search OTILONIUM+BROMIDE Search OTILONIUM+BROMIDE
2 OTILONIUM 488565 2% 80% 4 Search OTILONIUM Search OTILONIUM
3 PINAVERIUM 348973 2% 57% 4 Search PINAVERIUM Search PINAVERIUM
4 PINAVERIUM BROMIDE 274816 2% 60% 3 Search PINAVERIUM+BROMIDE Search PINAVERIUM+BROMIDE
5 BENZOCAINE HYDROCHLORIDE 152677 1% 100% 1 Search BENZOCAINE+HYDROCHLORIDE Search BENZOCAINE+HYDROCHLORIDE
6 GASTROINTESTINAL AFFERENTS 152677 1% 100% 1 Search GASTROINTESTINAL+AFFERENTS Search GASTROINTESTINAL+AFFERENTS
7 GUT SPASMOLYTIC 152677 1% 100% 1 Search GUT+SPASMOLYTIC Search GUT+SPASMOLYTIC
8 JEJUNUM COLON 152677 1% 100% 1 Search JEJUNUM+COLON Search JEJUNUM+COLON
9 LIZARD LIOLAEMUS TENUIS TENUIS 152677 1% 100% 1 Search LIZARD+LIOLAEMUS+TENUIS+TENUIS Search LIZARD+LIOLAEMUS+TENUIS+TENUIS
10 MUSCLE BATH 152677 1% 100% 1 Search MUSCLE+BATH Search MUSCLE+BATH

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 SHIN, BS , KIM, JJ , KIM, J , HU, SK , KIM, HJ , HONG, SH , KIM, HK , LEE, HS , YOO, SD , (2008) ORAL BIOAVAILABILITY AND ENTEROHEPATIC RECIRCULATION OF OTILONIUM BROMIDE IN RATS.ARCHIVES OF PHARMACAL RESEARCH. VOL. 31. ISSUE 1. P. 117-124 12 80% 5
2 EVANGELISTA, S , COCHET, P , BROMET, N , CRISCUOLI, M , MAGGI, CA , (2000) A DISTRIBUTION STUDY WITH C-14-OTILONIUM BROMIDE IN THE RAT: EVIDENCE FOR SELECTIVE TROPISM FOR LARGE INTESTINE AFTER ORAL ADMINISTRATION.DRUG METABOLISM AND DISPOSITION. VOL. 28. ISSUE 6. P. 643-647 12 86% 20
3 EVANGELISTA, S , (1999) OTILONIUM BROMIDE: A SELECTIVE SPASMOLYTIC FOR THE GASTROINTESTINAL TRACT.JOURNAL OF INTERNATIONAL MEDICAL RESEARCH. VOL. 27. ISSUE 5. P. 207 -222 17 55% 17
4 CIPRIANI, G , GIBBONS, SJ , SARAVANAPERUMAL, SA , MALYSZ, J , SHA, L , SZURSZEWSKI, JH , LINDEN, DR , EVANGELISTA, S , FAUSSONE-PELLEGRINI, MS , VANNUCCHI, MG , ET AL (2015) CHANGES IN NITRERGIC AND TACHYKININERGIC PATHWAYS IN RAT PROXIMAL COLON IN RESPONSE TO CHRONIC TREATMENT WITH OTILONIUM BROMIDE.NEUROGASTROENTEROLOGY AND MOTILITY. VOL. 27. ISSUE 7. P. 997 -1009 17 33% 0
5 EVANGELISTA, S , GIACHETTI, A , CHAPELAIN, B , NELIAT, G , MAGGI, CA , (1998) RECEPTOR BINDING PROFILE OF OTILONIUM BROMIDE.PHARMACOLOGICAL RESEARCH. VOL. 38. ISSUE 2. P. 111-117 11 65% 16
6 ZHAO, YR , DING, L , FAN, HW , YU, Y , QI, XM , LENG, Y , RAO, YK , (2010) DETERMINATION OF THE UNSTABLE DRUG OTILONIUM BROMIDE IN HUMAN PLASMA BY LC-ESI-MS AND ITS APPLICATION TO A PHARMACOKINETIC STUDY.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 878. ISSUE 28. P. 2896-2900 9 56% 1
7 PALAFOX, MA , (1997) FAR-INFRARED OF THE LOCAL ANESTHETIC PROCAINE.SPECTROSCOPY LETTERS. VOL. 30. ISSUE 8. P. 1495-1514 8 89% 2
8 RYCHTER, J , ESPIN, F , GALLEGO, D , VERGARA, P , JIMENEZ, M , CLAVE, P , (2014) COLONIC SMOOTH MUSCLE CELLS AND COLONIC MOTILITY PATTERNS AS A TARGET FOR IRRITABLE BOWEL SYNDROME THERAPY: MECHANISMS OF ACTION OF OTILONIUM BROMIDE.THERAPEUTIC ADVANCES IN GASTROENTEROLOGY. VOL. 7. ISSUE 4. P. 156 -166 13 30% 5
9 TRAINI, C , FAUSSONE-PELLEGRINI, MS , EVANGELISTA, S , MAZZAFERRO, K , CIPRIANI, G , SANTICIOLI, P , VANNUCCHI, MG , (2014) INNER AND OUTER PORTIONS OF COLONIC CIRCULAR MUSCLE: ULTRASTRUCTURAL AND IMMUNOHISTOCHEMICAL CHANGES IN RAT CHRONICALLY TREATED WITH OTILONIUM BROMIDE.PLOS ONE. VOL. 9. ISSUE 8. P. - 9 43% 2
10 REN, JM , ZHAO, X , WANG, CP , SUN, Q , YIN, LX , ZHANG, ZQ , (2011) A SENSITIVE AND SPECIFIC LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY METHOD FOR DETERMINATION OF PINAVERIUM BROMIDE IN HUMAN PLASMA: APPLICATION TO A PHARMACOKINETIC STUDY IN HEALTHY VOLUNTEERS.BIOMEDICAL CHROMATOGRAPHY. VOL. 25. ISSUE 12. P. 1369-1373 4 100% 1

Classes with closest relation at Level 1


Rank Class id link
1 35095 ANAESTHETIC PROCEDURE//ANESTHETIC VOLATILE SEVOFLURANE HALOTHANE ISOFLURANE//BLOOD COAGULATION DEGRANULATION
2 30417 3 CHLORO 1 5H DIBENZB FAZEPINE 5 YL PROPAN 1 ONE//DIBROMIDE RADICAL ANION//DITHIOCYANATE RADICAL ANION
3 37561 BICARBONATE SYSTEM//S CHIYODA KU//HORIZONTAL ASYMPTOTE
4 93 IRRITABLE BOWEL SYNDROME//IBS//VISCERAL HYPERSENSITIVITY
5 31784 TRIMEBUTINE//CAS 39133 31 8//CAS 34140 59 5
6 23054 TIROPRAMIDE//ILEAL MUSCLE//INTESTINE SMOOTH
7 28259 METHYLFLAVONOLAMINE//MUSCARINIC AUTOINHIBITION//CERVICAL SMOOTH MUSCLE
8 27176 SMOOTH MUSCLE INSUFFICIENCY//8 OH DPAT 8 HYDROXY 2 N DIPROPYLAMINOTETRALIN//ACUTE AND CHRONIC SEROTONIN INSUFFICIENCY
9 34371 H 1 SPIN LATTICE RELAXATION RATE//AFFINITY INDEX//LIGAND MACROMOLECULES INTERACTION
10 31667 AKW//ANESTHESIOL REANIMATHOL INTENS CARE//ATHYROID CARDIOMYOPATHY

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