Class information for:
Level 1: CYCLOSPORINE A//CYCLOSPORINE//NEPHROTOXICITY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2852 2130 30.3 77%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
98 3       TRANSPLANTATION//TRANSPLANTATION PROCEEDINGS//SURGERY 75394
93 2             TRANSPLANTATION//TRANSPLANTATION PROCEEDINGS//KIDNEY TRANSPLANTATION 26351
2852 1                   CYCLOSPORINE A//CYCLOSPORINE//NEPHROTOXICITY 2130

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYCLOSPORINE A authKW 340339 10% 11% 217
2 CYCLOSPORINE authKW 326533 13% 8% 271
3 NEPHROTOXICITY authKW 153635 9% 6% 188
4 CYCLOSPORINE NEPHROTOXICITY authKW 73392 1% 39% 13
5 TRANSPLANTATION PROCEEDINGS journal 65114 20% 1% 426
6 TRANSPLANTATION WoSSC 60112 35% 1% 744
7 CYCLOSPORIN A authKW 50947 4% 4% 82
8 CHRONIC NEPHROTOXICITY authKW 43675 0% 38% 8
9 CHRONIC CYCLOSPORINE A NEPHROTOXICITY authKW 43002 0% 100% 3
10 CYCLOSPORINE A CSA authKW 34136 0% 26% 9

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Transplantation 60112 35% 1% 744
2 Urology & Nephrology 11474 22% 0% 464
3 Immunology 8656 31% 0% 666
4 Surgery 8022 34% 0% 716
5 Pharmacology & Pharmacy 1165 16% 0% 337
6 Peripheral Vascular Diseases 436 5% 0% 105
7 Toxicology 283 4% 0% 90
8 Pathology 220 4% 0% 76
9 Cardiac & Cardiovascular System 194 5% 0% 108
10 Medicine, General & Internal 129 5% 0% 114

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEPHROL HEM HE E TRANSPLANTAT 32250 0% 75% 3
2 RENMIN HOSP QINGYUAN 28668 0% 100% 2
3 RENMIN HOSP YICHANG 28668 0% 100% 2
4 EXERCISE OXIDAT ST S GRP 17636 0% 31% 4
5 ANAL CLIN NEPHROL SECT 14334 0% 100% 1
6 BIOCHIM INGN PROTSECTEUR NORD 14334 0% 100% 1
7 BIOMED SCI HUMAN ONCOL MORBIDY ANAT SECT 14334 0% 100% 1
8 BIOQUIM CSIC UCM 14334 0% 100% 1
9 BIOQUM QUIM FARM 14334 0% 100% 1
10 CANTONAL HOSP PATHOL 14334 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TRANSPLANTATION PROCEEDINGS 65114 20% 1% 426
2 TRANSPLANTATION 27427 9% 1% 188
3 CLINICAL NEPHROLOGY 10040 3% 1% 59
4 KIDNEY INTERNATIONAL 8812 4% 1% 95
5 RENAL FAILURE 4573 2% 1% 34
6 NEPHROLOGY DIALYSIS TRANSPLANTATION 4227 3% 0% 61
7 NEPHRON 2811 1% 1% 31
8 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 2228 2% 0% 34
9 BRITISH JOURNAL OF EXPERIMENTAL PATHOLOGY 1653 0% 1% 10
10 EXPERIMENTAL NEPHROLOGY 1649 0% 1% 8

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CYCLOSPORINE A 340339 10% 11% 217 Search CYCLOSPORINE+A Search CYCLOSPORINE+A
2 CYCLOSPORINE 326533 13% 8% 271 Search CYCLOSPORINE Search CYCLOSPORINE
3 NEPHROTOXICITY 153635 9% 6% 188 Search NEPHROTOXICITY Search NEPHROTOXICITY
4 CYCLOSPORINE NEPHROTOXICITY 73392 1% 39% 13 Search CYCLOSPORINE+NEPHROTOXICITY Search CYCLOSPORINE+NEPHROTOXICITY
5 CYCLOSPORIN A 50947 4% 4% 82 Search CYCLOSPORIN+A Search CYCLOSPORIN+A
6 CHRONIC NEPHROTOXICITY 43675 0% 38% 8 Search CHRONIC+NEPHROTOXICITY Search CHRONIC+NEPHROTOXICITY
7 CHRONIC CYCLOSPORINE A NEPHROTOXICITY 43002 0% 100% 3 Search CHRONIC+CYCLOSPORINE+A+NEPHROTOXICITY Search CHRONIC+CYCLOSPORINE+A+NEPHROTOXICITY
8 CYCLOSPORINE A CSA 34136 0% 26% 9 Search CYCLOSPORINE+A+CSA Search CYCLOSPORINE+A+CSA
9 ARTERIOLOPATHY 32752 0% 29% 8 Search ARTERIOLOPATHY Search ARTERIOLOPATHY
10 APOPTOTIC MECHANISMS 28668 0% 100% 2 Search APOPTOTIC+MECHANISMS Search APOPTOTIC+MECHANISMS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MCNALLY, PG , FEEHALLY, J , (1992) PATHOPHYSIOLOGY OF CYCLOSPORINE-A NEPHROTOXICITY - EXPERIMENTAL AND CLINICAL OBSERVATIONS.NEPHROLOGY DIALYSIS TRANSPLANTATION. VOL. 7. ISSUE 8. P. 791-804 135 83% 92
2 NAESENS, M , KUYPERS, DRJ , SARWAL, M , (2009) CALCINEURIN INHIBITOR NEPHROTOXICITY.CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. VOL. 4. ISSUE 2. P. 481-508 104 30% 405
3 BURDMANN, EA , ANDOH, TF , YU, L , BENNETT, WM , (2003) CYCLOSPORINE NEPHROTOXICITY.SEMINARS IN NEPHROLOGY. VOL. 23. ISSUE 5. P. 465-476 67 77% 138
4 LASSILA, M , (2002) INTERACTION OF CYCLOSPORINE A AND THE RENIN-ANGIOTENSIN SYSTEM; NEW PERSPECTIVES.CURRENT DRUG METABOLISM. VOL. 3. ISSUE 1. P. 61 -71 74 67% 37
5 KOPP, JB , KLOTMAN, PE , (1990) CELLULAR AND MOLECULAR MECHANISMS OF CYCLOSPORINE NEPHROTOXICITY.JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. VOL. 1. ISSUE 2. P. 162-179 91 61% 170
6 BENNETT, WM , DEMATTOS, A , MEYER, MM , ANDOH, T , BARRY, JM , (1996) CHRONIC CYCLOSPORINE NEPHROPATHY: THE ACHILLES' HEEL OF IMMUNOSUPPRESSIVE THERAPY.KIDNEY INTERNATIONAL. VOL. 50. ISSUE 4. P. 1089-1100 70 53% 312
7 CARLOS, CP , MENDES, GEF , MIQUELIN, AR , LUZ, MAM , DA SILVA, CGA , VAN ROOIJEN, N , COIMBRA, TM , BURDMANN, EA , (2010) MACROPHAGE DEPLETION ATTENUATES CHRONIC CYCLOSPORINE A NEPHROTOXICITY.TRANSPLANTATION. VOL. 89. ISSUE 11. P. 1362-1370 47 60% 12
8 CAMPISTOL, JM , SPAIN, B , SACKS, SH , (2000) MECHANISMS OF NEPHROTOXICITY.TRANSPLANTATION. VOL. 69. ISSUE 12. P. SS5-SS10 47 75% 51
9 KOROLCZUK, A , MACIEJEWSKI, M , CZECHOWSKA, G , ORZEL-PANKOWSKA, M , (2013) ULTRASTRUCTURAL EXAMINATION OF RENAL TUBULAR EPITHELIAL CELLS AND HEPATOCYTES IN THE COURSE OF CHRONIC CYCLOSPORIN A TREATMENT-A POSSIBLE LINK TO OXIDATIVE STRESS.ULTRASTRUCTURAL PATHOLOGY. VOL. 37. ISSUE 5. P. 332 -339 34 69% 5
10 YANG, JJ , FINN, WF , (1998) EFFECT OF OXYPURINOL ON CYCLOSPORINE TOXICITY IN CULTURED EA, LLC-PK1 AND MDCK CELLS.RENAL FAILURE. VOL. 20. ISSUE 1. P. 85 -101 41 87% 12

Classes with closest relation at Level 1


Rank Class id link
1 15390 POST TRANSPLANT HYPERTENSION//POSTTRANSPLANTATION HYPERTENSION//POST TRANSPLANT NEPHROTIC SYNDROME
2 7788 TRANSPLANTATION PROCEEDINGS//STEROID WITHDRAWAL//CORTICOSTEROID WITHDRAWAL
3 1513 CYCLOSPORINE//C 2 MONITORING//NEORAL
4 16475 HEART TRANSPLANTATION//DUAL ORGAN TRANSPLANTATION//HEART KIDNEY TRANSPLANTATION
5 10535 TRANSPLANTATION PROCEEDINGS//TRANSPLANTATION//ANTIINFLAMMATORY AND IMMUNOSUPPRESSIVE DRUGS
6 24144 ABDOMINAL SURG SUB DI HRAGMAT TRANSPLANTA//MED GEN SURG 2//RENAL ALLOGRAFT THROMBOSIS
7 15400 THROMBOTIC MICROANGIOPATHY//SCHISTOCYTES//FRAGMENTED RED CELL
8 15661 VOCLOSPORIN//SOLUBLE MEMBRANE MOLECULES//UVB DITHRANOL TREATMENT
9 24761 URINE LEAK//1 HEXAMETHYL PROPYLENEAMINE OXIME//ACTIVITY IN BLOOD DRAINAGE BAG
10 36822 DONGSAN KIDNEY//DONG SAN KIDNEY//CATALASE H2O2

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