Class information for:
Level 1: ANANDAMIDE//FATTY ACID AMIDE HYDROLASE//N ACYLETHANOLAMINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2851 2131 50.2 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
497 3       CANNABINOID//ANANDAMIDE//ENDOCANNABINOIDS 22707
535 2             CANNABINOID//ENDOCANNABINOIDS//ANANDAMIDE 14838
2851 1                   ANANDAMIDE//FATTY ACID AMIDE HYDROLASE//N ACYLETHANOLAMINE 2131

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANANDAMIDE authKW 2054477 21% 32% 447
2 FATTY ACID AMIDE HYDROLASE authKW 1691137 10% 58% 205
3 N ACYLETHANOLAMINE authKW 1313303 5% 83% 110
4 ENDOCANNABINOIDS authKW 1127064 17% 21% 369
5 2 ARACHIDONOYLGLYCEROL authKW 1117698 8% 44% 176
6 PALMITOYLETHANOLAMIDE authKW 968367 5% 68% 99
7 N ACYLPHOSPHATIDYLETHANOLAMINE authKW 607075 2% 85% 50
8 FAAH authKW 605822 5% 41% 102
9 MONOACYLGLYCEROL LIPASE authKW 519504 3% 49% 74
10 OLEOYLETHANOLAMIDE authKW 464831 2% 66% 49

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 4404 28% 0% 595
2 Chemistry, Medicinal 3966 13% 0% 284
3 Biochemistry & Molecular Biology 3747 37% 0% 781
4 Neurosciences 1536 18% 0% 376
5 Biophysics 1235 10% 0% 206
6 Cell Biology 338 8% 0% 180
7 Chemistry, Organic 218 6% 0% 133
8 Biochemical Research Methods 198 4% 0% 89
9 Chemistry, Analytical 93 4% 0% 94
10 Anesthesiology 61 1% 0% 29

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ENDOCANNABINOID GRP 426088 6% 25% 120
2 UNITE CHIM PHARMACEUT RADIOPHARM 197461 2% 42% 33
3 PHARMACOL CLIN NEUROSCI 184233 4% 16% 79
4 PLANT LIPID 135259 1% 39% 24
5 IST CHIM MOL INTE SE BIOL 89211 2% 17% 36
6 SKAGGS CHEM BIOL 64268 6% 3% 132
7 XIAMEN CHIRAL DRUGS 57309 0% 100% 4
8 IST CIBERNET 56458 2% 10% 38
9 GILL BIOMOL SCI 42133 1% 18% 16
10 BIOANAL PHARMACOL BIOACT LIPIDS GRP 41669 0% 36% 8

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 8064 2% 1% 39
2 CHEMISTRY AND PHYSICS OF LIPIDS 6687 2% 1% 39
3 BRITISH JOURNAL OF PHARMACOLOGY 6288 4% 1% 89
4 CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS 5820 1% 2% 19
5 VITAMINS AND HORMONES SERIES 4015 0% 6% 5
6 JOURNAL OF MEDICINAL CHEMISTRY 3748 4% 0% 76
7 PROSTAGLANDINS & OTHER LIPID MEDIATORS 2831 1% 1% 19
8 PHARMACOLOGICAL RESEARCH 2725 1% 1% 28
9 JOURNAL OF LIPID RESEARCH 2497 2% 0% 39
10 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2452 3% 0% 67

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ANANDAMIDE 2054477 21% 32% 447 Search ANANDAMIDE Search ANANDAMIDE
2 FATTY ACID AMIDE HYDROLASE 1691137 10% 58% 205 Search FATTY+ACID+AMIDE+HYDROLASE Search FATTY+ACID+AMIDE+HYDROLASE
3 N ACYLETHANOLAMINE 1313303 5% 83% 110 Search N+ACYLETHANOLAMINE Search N+ACYLETHANOLAMINE
4 ENDOCANNABINOIDS 1127064 17% 21% 369 Search ENDOCANNABINOIDS Search ENDOCANNABINOIDS
5 2 ARACHIDONOYLGLYCEROL 1117698 8% 44% 176 Search 2+ARACHIDONOYLGLYCEROL Search 2+ARACHIDONOYLGLYCEROL
6 PALMITOYLETHANOLAMIDE 968367 5% 68% 99 Search PALMITOYLETHANOLAMIDE Search PALMITOYLETHANOLAMIDE
7 N ACYLPHOSPHATIDYLETHANOLAMINE 607075 2% 85% 50 Search N+ACYLPHOSPHATIDYLETHANOLAMINE Search N+ACYLPHOSPHATIDYLETHANOLAMINE
8 FAAH 605822 5% 41% 102 Search FAAH Search FAAH
9 MONOACYLGLYCEROL LIPASE 519504 3% 49% 74 Search MONOACYLGLYCEROL+LIPASE Search MONOACYLGLYCEROL+LIPASE
10 OLEOYLETHANOLAMIDE 464831 2% 66% 49 Search OLEOYLETHANOLAMIDE Search OLEOYLETHANOLAMIDE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 TUO, W , LELEU-CHAVAIN, N , SPENCER, J , SANSOOK, S , MILLET, R , CHAVATTE, P , (2017) THERAPEUTIC POTENTIAL OF FATTY ACID AMIDE HYDROLASE, MONOACYLGLYCEROL LIPASE, AND N-ACYLETHANOLAMINE ACID AMIDASE INHIBITORS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 60. ISSUE 1. P. 4 -46 152 89% 0
2 BLANKMAN, JL , CRAVATT, BF , (2013) CHEMICAL PROBES OF ENDOCANNABINOID METABOLISM.PHARMACOLOGICAL REVIEWS. VOL. 65. ISSUE 2. P. 849-871 125 63% 105
3 UEDA, N , TSUBOI, K , UYAMA, T , (2013) METABOLISM OF ENDOCANNABINOIDS AND RELATED N-ACYLETHANOLAMINES: CANONICAL AND ALTERNATIVE PATHWAYS.FEBS JOURNAL. VOL. 280. ISSUE 9. P. 1874-1894 122 73% 52
4 SAARIO, SM , NEVALAINEN, T , MINKKILA, A , (2010) DISCOVERY AND DEVELOPMENT OF ENDOCANNABINOID-HYDROLYZING ENZYME INHIBITORS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 10. ISSUE 8. P. 828 -858 145 78% 33
5 EZZILI, C , OTRUBOVA, K , BOGER, DL , (2010) FATTY ACID AMIDE SIGNALING MOLECULES.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. VOL. 20. ISSUE 20. P. 5959-5968 138 78% 46
6 OTRUBOVA, K , CRAVATT, BF , BOGER, DL , (2014) DESIGN, SYNTHESIS, AND CHARACTERIZATION OF ALPHA-KETOHETEROCYCLES THAT ADDITIONALLY TARGET THE CYTOSOLIC PORT CYS269 OF FATTY ACID AMIDE HYDROLASE.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 57. ISSUE 3. P. 1079 -1089 100 90% 8
7 UEDA, N , TSUBOI, K , UYAMA, T , (2010) N-ACYLETHANOLAMINE METABOLISM WITH SPECIAL REFERENCE TO N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE (NAAA).PROGRESS IN LIPID RESEARCH. VOL. 49. ISSUE 4. P. 299-315 130 68% 62
8 AHN, K , MCKINNEY, MK , CRAVATT, BF , (2008) ENZYMATIC PATHWAYS THAT REGULATE ENDOCANNABINOID SIGNALING IN THE NERVOUS SYSTEM.CHEMICAL REVIEWS. VOL. 108. ISSUE 5. P. 1687 -1707 115 64% 222
9 LAMBERT, DM , FOWLER, CJ , (2005) THE ENDOCANNABINOID SYSTEM: DRUG TARGETS, LEAD COMPOUNDS, AND POTENTIAL THERAPEUTIC APPLICATIONS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 48. ISSUE 16. P. 5059-5087 182 47% 222
10 NICOLUSSI, S , GERTSCH, J , (2015) ENDOCANNABINOID TRANSPORT REVISITED.HORMONES AND TRANSPORT SYSTEMS. VOL. 98. ISSUE . P. 441 -485 104 73% 7

Classes with closest relation at Level 1


Rank Class id link
1 241 CANNABINOID//CANNABINOID RECEPTORS//CB2 RECEPTOR
2 17994 SEZ F BOTTAZZI//SEZ BOTTAZZI//DIPARTIMENTO STUDI
3 29527 2 ARACHIDONOYLGLYCEROL ANANDAMIDE//ANANDAMIDE TRANSPORT INHIBITORS//ANTIGLAUCOMA ACTIVITY
4 651 CANNABINOID//CB1 RECEPTOR//ENDOCANNABINOIDS
5 8413 RIMONABANT//ENDOCANNABINOIDS//TARANABANT
6 33037 TIG3//RARRES3//H REV107
7 13434 CHEMICAL PROTEOMICS//ACTIVITY BASED PROTEIN PROFILING//ACTIVITY BASED PROBES
8 1728 TRPV1//CAPSAICIN//RESINIFERATOXIN
9 34588 GLYCINE N ACYLTRANSFERASE//MEDIUM CHAIN ACYL COA SYNTHETASE//GLYCINE CONJUGATION
10 34013 GLYCEROPHOSPHOINOSITOL//GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE//GDE DOMAIN

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